• Title/Summary/Keyword: Crude drug

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Studies on the Umbelliferous Rhizoma and Root(III) -The Original Plant of Korean Qianghuo (Gangwhal)- (미나리과 식물(植物)의 지하부(地下部)에 관한 연구(硏究)(III) -우리나라산(産) 강활(羌活)에 대하여-)

  • Suk, Kuy-Duk
    • Korean Journal of Pharmacognosy
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    • v.7 no.1
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    • pp.25-33
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    • 1976
  • Ostericum praeteritum $K_{ITAGAWA}(=Angelica\;koreana\;M_{AXIM}.)$ has been regarded as the original plant of Korean Qianghuo. The morphological and anatomical examination were made on Korean Qianghuo (crude drug fruits, purchased at markets and cultivated), and compared with Gangwhal $(O.\;praeteritum\;K_{ITAG}.)$. It was found that 3 species $A.\; polymorpha\;M_{AXIM}.,O.\;grosseserratum\;K_{ITAG}.,\;and\;O.\;sieboldi \;N_{AKAI}$. were different from Gangwhal. The original plant of Korean Qianghuo was identified as $A.\;polymorpha\;M_{AXIM}$, through this study.

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Pharmacognostical Studies on Alisma Plants (택사의 생약학적 연구)

  • Toh, Chung-Ae
    • Korean Journal of Pharmacognosy
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    • v.26 no.4
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    • pp.411-418
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    • 1995
  • In order to clarify the originality of several Alisma Rhizomes, we investigated the differences of their morphological, anatomical and physiochemical characteristics. Morphological observation shows the variability of Alisma shape and quality. The diversities in morphological shapes and qualities of tuber were observed among different origins. Chinese product looked like corm shape, but korean's irregular shape. The microscopic observation of korean Alisma revealed the presence of irregular vascular bundle which was scattered transversely and longitudinaly, which was different from that of the rhizome. This facts suggest that the portion of crude drug in Alisma should be the corm rather than the rhizome. In the physicochemical differences, chinese Alisma contains larger amount of mineral elements such as K, Na and Ca than korean Alisma. On the contrary, protein contents in lyophilized powder of aqueous extracts in korean Alisma rhizome was significantly higher than chinese Alisma rhizome. The leaves and stems contained larger amount of Ca and Na than tuber, and may be used as the osmotic diuretics for chinese traditional medicine.

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Studies on the Efficacy of Combined Preparations of Crude Drug (II) -The Effect of ‘Kamisamhwang-Tang’ on Cardiovascular System and Antibacterial Activities- (생약복합제제(生藥複合製劑)의 약효연구(藥效硏究) (제2보)(第2報) -가미삼황탕(加味三黃湯)이 순환기계(循環器系) 및 항균작용(抗菌作用)에 대(對)하여-)

  • Hong, N.D.;Kim, J.W.;Song, I.B.;Kim, N.J.
    • Korean Journal of Pharmacognosy
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    • v.12 no.4
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    • pp.190-194
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    • 1981
  • It was prevously shown that 'Kamisamhwang-Tang' had been examined for effects of the anticonvulsion, antipyretic, analgesic and sedative. To investigate the effect on cardiovascular system and antibacterial activities, pharmacological studies have been carried out with each extract. The results of this investigation were summarized as follows: 1) 'Kamisamhwang-Tang' depressed central convulsion induced by strychnine, picrotoxine and caffeine in mice. 2) Antipyretic, analgesic and sedative action were observed. 3) Hypotensive effect was observed in rabbits. 4) Antibacterial activities was observed.

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Gas Chromatographic Analysis and Cholinesterase Activity of the Essential Oil from Korean Agastache rugosa (기체크로마토그래피에 의한 한국산 배초향의 정유 분석과 Cholinesterase 억제활성)

  • Choi, Jae Sue;Song, Byong-Min;Park, Hee-Juhn
    • Korean Journal of Pharmacognosy
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    • v.47 no.2
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    • pp.192-196
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    • 2016
  • The herb of Agastache rugosa (Lamiaceae) called Korean mint as a spice or Agastache Herba as a crude drug is known to contain highly fragrant volatile substances. This research aimed to establish the quantitative gas chromatography (GC) method on the essential oil of A. rugosa using the three standard compounds, estragole, methyleugenol, pulegone, and to find whether the essential oil has anti-Alzheimer's activity. The GC quantification method was established by determining the linearity of calibration curve ($R^2$), linear range, and both limit-of-detection (LOD) and limit-of-quantification (LOQ). The $IC_{50}$ of the essential oil on the activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were determined to be $69.06{\pm}0.26$ and $76.71{\pm}0.58{\mu}g/ml$, respectively.

Acne-remedy Effects of Extract Mixture of Pulsatillae Radix and Cicadidae Periostracum (백두옹(白頭翁) 및 선퇴(蟬退) 추출 혼합물의 분자 개선 효과)

  • Lim, Jong-Pil
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.4
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    • pp.653-660
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    • 2010
  • Pulsatillae Radix and Cicadidae Periostracum have long been used for treatment of injuries, inflammations or itchiness in Korea. This study was carried out to examine the acne-remedy effects of the mixture made with equal parts of Pulsatillae Radix extract and Cicadidae Periostracum extract (PRCP) compared with 2%-benzoyl peroxide (Standard) used commercially as anti-acne. The results showed the mixture (PRCP) was more effective than each crude drug extract. The 10%-PRCP showed significant antimicrobial activity against Propionibacterium acnes, the major cause of acne, and also showed significant inhibition from type 1 $5{\alpha}$-reductase ($5{\alpha}R$), another cause of acne, And the cream made with PRCP demonstrated anti-sebum and acne-improvement effects on examinee's facial skin.

Pharmacognostical Study on the Korean Folk Medicine 'Da Rae Ip' (한국 민간약 다래잎의 생약학적 연구)

  • Lee, Yu-Jin;Choi, Jeong-Ku;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.36 no.1 s.140
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    • pp.26-33
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    • 2005
  • Korean folk medicine 'Da Rae Ip' has been used to cure intestinal catarrh, stomach cancer and acute gastritis. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'Da Rae Ip', the morphological and anatomical characteristics of the leaves of Actinidia species growing in Korea and Japan; i.e. A. arguta, A. arguta var. rufinervis, A. kolomikta, A. polygama, A. rufa were studied. As a result, it was clarified that 'Da Rae Ip' was the leaf of Actinidia arguta and Actinidia polygama.

Pharmacognostical Evaluation of Sphaeranthus indicus (Linn.)

  • Prabhu, Kirti. S.;Lobo, Richard;Kumar, C. Dinesh;Rajendran, K.;Shirwaikar, Annie
    • Natural Product Sciences
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    • v.12 no.2
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    • pp.85-88
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    • 2006
  • This study presents a detailed pharmacognostical study of the underground portion of the crude drug Sphaeranthus indicus Linn. (Asteraceae), an important plant in the Indian system of medicine. The root and stolon were studied using procedures of light, conofocal microscopy, WHO recommended-physicochemical determinations, and authentic phytochemical procedures. The physicochemical, morphological, and histological parameters presented in this paper may be proposed as parameters to identify and establish the authenticity of S. indicus root and stolon.

Pharmacognostical Studies on the 'O Ga Pi Ip' (오가피잎의 생약학적 연구)

  • Lee, Eun-Sook;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.37 no.1 s.144
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    • pp.1-10
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    • 2006
  • 'O Ga Pi Ip' has been used in Korea to cure rheumatism, neuralgia, edema, dematopathy, and impotence. The botanical origin of the crude drug has not been confirmed pharmacognostically. To clarify the botanical origin of 'O Ga Pi Ip', the morphological and anatomical characteristics of the leaves of Acanthopanax species growing in Korea and Japan, A. chi-isanensis Nakai, A. Koreanum Nakai, A. rufinerve Nakai, A. senticosus (Rupr.et Maxim). Harms, A senticosus (Rupr.et Maxim.) for inermis Harms, A. seoulense Nakai, A sessiliflorus (Rupr. et Maxim.) Seem, A. divaricatus Seem, A. sieboldianum Makino were compared. As a result, it was determined that 'O Ga Pi Ip' was the leaf of A. sessiliflorus (Rupr. et Maxim.) Seem, A chiisanensis Nakai, and A. koreanum $Nakai_I$.

Pharmacognostical Studies on the Folk medicine 'Koaeng I Bab' (민간약 괭이밥의 생약학적 연구)

  • Kim, Jeong-Myo;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.32 no.3 s.126
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    • pp.233-237
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    • 2001
  • Korean folk medicine 'Koaeng I Bab' has been used to cure hemorrhoid, boil and dermatopathy and as an antidote. The botanical origin of the crude drug has not been studied pharmacognostically. To clarify the botanical origin of 'Koaeng I Bab', the morphological and anatomical characteristics of the leaves of Oxalis species growing in Korea, i.e. O. acetosella, O. acetosella var. purpurascens, O. corniculata, O. obtriangulata were studied. As the result, the botanical origin of 'Koaeng I Bab' has been proved to be O. corniculata and O. acetosella var. purpurascens.

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Pharmacognostical Studies on the Folk Medicine 'Am Cho' (민간약 "암초"의 생약학적 연구)

  • Park, Seong-Su;Kim, Jeong-Myo;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.32 no.2 s.125
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    • pp.128-134
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    • 2001
  • The Korean folk medicine 'Am Cho' has been used as the folk remedy for diuretic, stomach and liver cancer. The botanical origin of the crude drug has not been studied pharmacognostically. To clarify the botanical origin of 'Am Cho', the comparative morphological and anatomical characteristics have been studied of Lepisorus species growing wild in Korea, i.e. L. annuifrons, L. onoei, L. thunbergianus, L. ussuriensis and 'Am Cho' form Korea. As a result, it was clarified that 'Am Cho' from Korea was derived from Lepisorus onoei.

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