• Journal of Korean Society of Steel Construction
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• v.27 no.6
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• pp.503-511
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• 2015

In long span steel structure, the plate girder reinforced with stiffeners are commonly used. When choosing the cross section with deep depth of girder as well as narrow width, however, out of plane buckling can be a problem due to web slenderness. In an effort to solve this issue, current study determined the applicability of using corrugated web girder with deep depth as bending member, which is generally being utilized in both factory and warehouse nationwide. To accomplish this, we performed the loading test of H-shaped beam with sinusoidal corrugated web. Corrugated web CP-2.3 specimen exhibited 12% less maximal bending strength but CP-3.2 specimen exerted 24% increase in strength compared to plate web P-4.5. this result indicates that corrugated web provides enough strength even with unfavorable width-thickness ratio of plate. And bending as well as shear strength estimated by the Eurocode (EN 1993-1-5) were compared with both bending strength by loading test and shear strength estimated by KBC2009. In case of eurocode, increase in plate thickness did not help in bending performance improvement. moreover, shear performance was sensitive to the thickness of the web folds and the shape of the web plate.

• Journal of the Korea Concrete Institute
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• v.26 no.1
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• pp.3-12
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• 2014

Hybrid Truss Bridge (HTB) uses steel truss webs instead of concrete webs in prestressed box girder bridges, which is becoming popular due to its structural benefits such as relatively light self-weight and good aesthetics appearance. Since the core technology of this bridge is the connection system between concrete slabs and steel truss members, several connection systems were proposed and experimentally evaluated. Also, the selected joint system was applied to the real bride design and construction. The research was performed on the connection system, since it can affect the global behavior of this bridge such as flexural and fatigue behaviors as well as the local behavior around the connection region. The evaluation study showed that HTB applied to a curved bridge or an eccentrically loaded bridge had a weak torsional capacity compared to an ordinary PSC box girder bridge due to the open cross-sectional characteristic of HTB. Therefore, three types of girders with different joint system between truss web member and concrete slab were tested for their torsional capacity. In this study, the three different types of HTB girders under torsional loading were simulated using FEM analysis to investigate the torsional behavior of HTB girders more in detail. The results are discussed in detail in the paper.

• IMMUNE NETWORK
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• v.3 no.1
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• pp.16-22
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• 2003

Background: The S100A2 gene, also known as S100L or CaN19, encodes a protein comprised of 99-amino acids, is a member of the calcium-binding proteins of EF-hand family. According to a recent study, this gene was over-expressed in several early and malignant carcinomas compared to normal tissues. To elucidate the role of S100A2 protein in the process during carcinogenesis, production of monoclonal antibody specific to the protein is essential. Methods: First, cDNA sequence coding for ORF region of human S100A2 gene was amplified and cloned into an expression vector to produce GST fusion protein. Recombinant S100A2 protein and subsequently, monoclonal antibody to the protein were produced. The specificity of anti-S100A2 monoclonal antibody was confirmed by immunoblot analysis of cross reactivity to other recombinant proteins of S100A family (GST-S100A1, GST-S100A4 and GST-S100A6). To confirm the relation of S100A2 to cervical carcinogenesis, S100A2 protein in early cervical carcinoma tissue was immunostained using the monoclonal antibody. Results: GST-S100A2 recombinant protein was purified by affinity chromatography and then fusion protein was cleaved and S100A2 protein was isolated. The monoclonal antibody (KK0723; Korean patent pending #2001-30294) to the protein was produced and the antibody did not react with other members of EF-hand family proteins such as S100A1, S100A4 and S100A6. Conclusion: These data suggest that anti-S100A2 monoclonal antibody produced in this study can be very useful for the early detection of cervical carcinoma and elucidation of mechanism during the early cervical carcinogenesis.

• Journal of Korean Society of Steel Construction
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• v.19 no.6
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• pp.611-620
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• 2007

The beam-column connection is the critical design section of general steel frame structures owing to the behavioral characteristics of the structural system. As most members of a frame structure are composed of rolled section beams, the cross-section of the beam members is governed by the negative bending moment near beam-column connections. Such a design concept leaves a redundant load-carrying capacity at the positive bending regions of the beam members leading to design inefficiency. Therefore, it is of utmost importance to redistribute the beam end moments and reduce the stresses at the beam-column connections for a more efficient design of steel frame structures. In this study, reaction-moment prestressing method (RMPM) was proposed for the innovative design and construction of steel frame structures. The RMPM is a prestressing method utilizing the elastic bending deformation of a beam member induced by temporary prestressing for the distribution of a relatively large bending moment to other sections for the efficient use of the beam section. By the application of the RMPM, the negative bending moment at the beam-column connections can be significantly reduced, ultimately leading to possible use of smaller beam sections. Through a series of model tests and numerical analyses of steel frame structures, the moment distributing effect and feasibility of the RMPM was verified.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.2
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• pp.187-196
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• 2020

Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (F_ST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r² = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r² = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

• Journal of the Korean Wood Science and Technology
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• v.46 no.1
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• pp.85-92
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• 2018

In order to use glued built up timber beam as a structural member for post and beam construction, it must be possible to manufacture long-span lumber. In this study, the researchers conducted a performance evaluation for longitudinal bonding of lumber (cross-section $89{\times}120mm$) made from larch. The specimens were prepared in six different forms using the longitudinal bonding method. The bonding strength of these specimens was tested through tensile strength tests and bending strength tests. The tensile strength test result of the longitudinally bonded parts was better than that of the double lap specimens. And, the tensile strength value of the scarf specimen was better than that of the hooked scarf specimen. The tensile strength of the GFRP (Glass Fiber Reinforced Plastic) rod insertion bonding specimen was 3.6 MPa, which was the highest. As for the bending strength test result of the longitudinally bonded part, the average MOR (modulus of rupture) of the specimen where a GFRP rod was inserted and bonded measured 29 MPa, while the specimens of other bonded parts showed a MOR no more than 11 MPa. Toughness destruction was observed in specimens where a GFRP rod was insertion-bonded. The rest of the specimens showed brittle destruction. The average MOR strength of the Rod + Lap specimen was 30.5 MPa, which was the highest among all longitudinally bonded specimens. The bending strength of the Rod + Lap specimens showed an effective strength that was 66% of that of the control group which were not longitudinally bonded.

• Journal of the Korea Concrete Institute
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• v.21 no.6
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• pp.789-796
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• 2009

The randomness in the strength of a RC member is caused mainly by the variability of the mechanical properties of concrete and steel, the dimensions of concrete cross sections, and the placement of reinforcing bars and so on . Among those variations, the randomness and uncertainty of mechanical properties of concrete, such as compressive strength, tensile strength, and elastic modulus give the most significant influences and show relatively large statistical variations. In Korea, there has been little effort for the construction of its own statistical models for mechanical properties of concrete and steel, thus the foreign data have been utilized till now. In this paper, variability of compressive strength, tensile strength and elastic modulus of normal-weight structural concrete with various specified design compressive strength levels are examined based on the data obtained from a number of published and unpublished sources in this country and additional laboratory tests done by the authors. The inherent probabilistic models for compressive and tensile strength of normal-weight concrete are proposed as Gaussian distribution. Also, the relationships between compressive and splitting tensile strength and between compressive strength and elastic modulus in current KCI Code are verified and new ones are suggested based on local data.

• Journal of the Korea Concrete Institute
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• v.28 no.3
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• pp.365-373
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• 2016

Ultra-High-Performance Steel Fiber-Reinforced Concrete (SUPER Concrete) exhibits improved compressive and tensile strengths far superior to those of conventional concrete. These characteristics can significantly reduce the cross sectional area of the member and the anchorage strength of a headed bar is expected to be improved. In this study, the anchorage strengths of headed bars with $4d_b$ or $6d_b$ embedment length were evaluated by simulated exterior beam-column joint tests where the headed bars were used as beam bars and the joints were cast of 120 or 180 MPa SUPER Concrete. In all specimens, the actual yield strengths of the headed bars over 600 MPa were developed. Some headed bars were fractured due to the high anchorage capacity in SUPER Concrete. Therefore, the headed bar with only $4d_b$ embedment length in 120 MPa SUPER Concrete can develop a yield strength of 600 MPa which is the highest design yield strength permitted by the KCI design code. The previous model derived from tests with normal concrete and the current design code underestimate the anchorage capacity of the headed bar anchored in SUPER Concrete. Because the previous model and the current design code do not consider the effects of the high tensile strength of SUPER Concrete. From a regression analysis assuming that the anchorage strength is proportional to $(f_{ck})^{\alpha}$, the model for predicting anchorage strength of headed bars in SUPER Concrete is developed. The average and coefficient of variation of the test-to-prediction values are 1.01 and 5%, respectively.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3981-3990
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• 2015

Background: Breast cancer is the most common type of cancer in Jordan. Current efforts are focused on annual campaigns aimed at increasing awareness about breast cancer and encouraging women to conduct mammogram screening. In the absence of regular systematic screening for breast cancer in Jordan, there is a need to evaluate current mammography screening uptake and its predictors, assess women's knowledge and attitudes towards breast cancer and screening mammograms and to identify barriers to this preventive service. Materials and Methods: This cross-sectional study was conducted in six governorates in Jordan through face-to-face interviews on a random sample of women aged 40 to 69 years. Results: A total of 507 participants with mean age of $46.8{\pm}7.8$ years were interviewed. There was low participation rate in early detection of breast cancer practices. Breast self-examination, doctor examination and periodic mammography screening were reported by 34.9%, 16.8% and 8.6% of study participants, respectively. Additionally 3.8% underwent breast cancer screening at least once but not periodically, while 87.6% had never undergone mammography screening. Reported reasons for conducting the screening were: perceived benefit (50%); family history of breast cancer (23.1%); perceived severity (21.2%); and advice from friend or family member (5.8%). City residents have shown higher probability of undergoing mammogram than those who live in towns or villages. Results revealed negative perceptions and limited knowledge of study participants on breast cancer and breast cancer screening. The most commonly reported barriers for women who never underwent screening were: fear of results (63.8%); no support from surrounding environment (59.7); cost of the test (53.4%); and religious belief, i.e. Qadaa Wa Qadar (51.1%). Conclusions: In the absence of regular systematic screening for breast cancer in Jordan, the uptake of this preventive service is very low. It is essential for the country of Jordan to work on applying regular systematic mammography screening for breast cancer. Additionally, there is a need for improvement in the current health promotion programmes targeting breast cancer screening. Other areas that could be targeted in future initiatives in this field include access to screening in rural areas and removal of current barriers.

• Management & Information Systems Review
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• v.37 no.2
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• pp.209-233
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• 2018

This study investigates the question of how political and economic factors may affect the export of renewable energy technologies. The relationships are tested using panel data for 19 OECD member countries over the period 1992-2012. Before establishing the empirical model, the current study checks the characteristics of the panel data, which includes various panel framework analyses, such as tests for the presence of normality, structural breaks, first-order autocorrelation, heteroscedasticity, cross-sectional dependence, panel unit-root. From the panel framework analyses, a dynamic panel model is established to test the relationship between the variables examined in this study. In order to reduce the bias of the estimation of the dynamic panel model and obtain efficient parameters, this study uses the bias-corrected least square dummy variable(LSDVC) estimator to estimate the empirical model. The results of this study show that governmental policies expressed as coercive pressure and market size positively affect the export growth of renewable energy technologies. However, public pressure and traditional energy industry have no significant effects on export performance. Policy implications are presented based on the results of this study.