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Gene Sequences Clustering for the Prediction of Functional Domain (기능 도메인 예측을 위한 유전자 서열 클러스터링)

  • Han Sang-Il;Lee Sung-Gun;Hou Bo-Kyeng;Byun Yoon-Sup;Hwang Kyu-Suk
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.10
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    • pp.1044-1049
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    • 2006
  • Multiple sequence alignment is a method to compare two or more DNA or protein sequences. Most of multiple sequence alignment tools rely on pairwise alignment and Smith-Waterman algorithm to generate an alignment hierarchy. Therefore, in the existing multiple alignment method as the number of sequences increases, the runtime increases exponentially. In order to remedy this problem, we adopted a parallel processing suffix tree algorithm that is able to search for common subsequences at one time without pairwise alignment. Also, the cross-matching subsequences triggering inexact-matching among the searched common subsequences might be produced. So, the cross-matching masking process was suggested in this paper. To identify the function of the clusters generated by suffix tree clustering, BLAST and CDD (Conserved Domain Database)search were combined with a clustering tool. Our clustering and annotating tool consists of constructing suffix tree, overlapping common subsequences, clustering gene sequences and annotating gene clusters by BLAST and CDD search. The system was successfully evaluated with 36 gene sequences in the pentose phosphate pathway, clustering 10 clusters, finding out representative common subsequences, and finally identifying functional domains by searching CDD database.

The Determinants of Switching On·Off-Line Channels for Consumers (소비자의 온·오프라인 채널이동 유형의 결정요인에 대한 연구)

  • Jun, Sangmin
    • Journal of Digital Convergence
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    • v.11 no.12
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    • pp.245-256
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    • 2013
  • This study illustrates factors that determine consumer types based on ways in which they alternate between online and offline channels for searching and eventually buying their desired products. This study conducted an online survey targeting 1,040 consumers. As per the study, consumer types fall into five groups: 1) on-on type(online search${\rightarrow}$online buying), 2) off-off type(offline search${\rightarrow}$offline buying), 3) on-off type(online search${\rightarrow}$offline buying), 4) off-on type(offline search${\rightarrow}$online buying), and, 5) on-off-on type(online search${\rightarrow}$ offline search${\rightarrow}$nline buying). The primary factors that determine how the different consumer types switch between online and offline channels are price orientation, convenience orientation,, risk-aversion orientation, and channel familiarity. Although they feel cross-channel shopping can be cumbersome, the findings show that cross-channel consumers would gladly switch channels to buy cheaper and proven products. The findings of this study will be useful for businesses that have both online and offline channels and point out the theoretical aspects of the decision-making process as consumers switch between channels.

Efficient Integer pel and Fractional pel Motion Estimation on H.264/AVC (H.264/AVC에서 효율적인 정화소.부화소 움직임 추정)

  • Yoon, Hyo-Sun;Kim, Hye-Suk;Jung, Mi-Gyoung;Kim, Mi-Young;Cho, Young-Joo;Kim, Gi-Hong;Lee, Guee-Sang
    • The KIPS Transactions:PartB
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    • v.16B no.2
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    • pp.123-130
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    • 2009
  • Motion estimation (ME) plays an important role in digital video compression. But it limits the performance of image quality and encoding speed and is computational demanding part of the encoder. To reduce computational time and maintain the image quality, integer pel and fractional pel ME methods are proposed in this paper. The proposed method for integer pel ME uses a hierarchical search strategy. This strategy method consists of symmetrical cross-X pattern, multi square grid pattern, diamond patterns. These search patterns places search points symmetrically and evenly that can cover the overall search area not to fall into the local minimum and to reduce the computational time. The proposed method for fractional pel uses full search pattern, center biased fractional pel search pattern and the proposed search pattern. According to block sizes, the proposed method for fractional pel decides the search pattern adaptively. Experiment results show that the speedup improvement of the proposed method over Unsymmetrical cross Multi Hexagon grid Search (UMHexagonS) and Full Search (FS) can be up to around $1.2{\sim}5.2$ times faster. Compared to image quality of FS, the proposed method shows an average PSNR drop of 0.01 dB while showing an average PSNR gain of 0.02 dB in comparison to that of UMHexagonS.

Modified harmony search and its application to cost minimization of RC columns

  • Medeiros, Guilherme F.;Kripka, Moacir
    • Advances in Computational Design
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    • v.2 no.1
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    • pp.1-13
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    • 2017
  • This paper presents a variant of the Harmony Search Algorithm (HS) and its application to discrete optimization. The main proposed modifications regarding original HS are related to stopping criterion and reinitialization of population, called Harmony Memory. In order to investigate the efficiency of the algorithm, it was applied for obtaining optimal sections of reinforced concrete columns subjected to uniaxial flexural compression. To minimize the cost of the section, the amount and diameters of the reinforcement bars and the dimensions of the columns cross sections were considered as design variables. The obtained results were compared to those generated by other optimization methods. Since, to the examples, Harmony Search reached the same results achieved by Simulated Annealing, some additional analysis are presented in order to compare these methods regarding success rate and number of iterations to reach the optimum.

Fast Uneven Multi-Hexagon-Grid Search Algorithm for Integer Pel Motion Estimation of H.264 (H.264 의 고속 정수 단위 화소 움직임 예측을 위한 개선된 Uneven Multi-Hexagon-grid 검색 알고리즘)

  • Lee In-Jik;Kim Cheong-Ghil;Kim Shin-Dug
    • Proceedings of the Korea Information Processing Society Conference
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    • 2006.05a
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    • pp.153-156
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    • 2006
  • 본 논문에서는 H.264 표준화 기구인 Joint Video Team(JVT) 권고안의 정수 단위 화소 움직임 예측을 위한 Unsymmetrical-cross Multi-Hexagon-grid Search(UMHexagonS) 알고리즘에서 Uneven Multi-Hexagon-grid Search(UMHGS) 부분을 개선한 알고리즘을 제안한다. 제안하는 알고리즘은 이전 프레임의 동일위치 또는 상위 모드에서 이미 선택된 움직임 벡터(MV: Motion Vector)를 이용하여 신호 대 잡음 비(PSNR: Peak Signal to Noise Ratio) 및 평균 비트 율(Average Bitrates)을 유지하면서, 현재 매크로블록의 검색영역을 줄이는 것이 가능하다. 제안하는 알고리즘의 성능은 Full Search Block Matching Algorithm(FSBMA) 및 UMHexagonS 알고리즘의 integer pel 에 대한 SAD(Sum of Absolute Difference) 연산횟수로 비교평가 하였다. 그 결과, FSBMA 에 비하여 평균 97.64%, UMHexagonS 에 비하여는 평균 17.48%의 연산횟수를 감소시키는 우수함을 보였다.

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An Adaptive Fast Motion Estimation Based on Directional Correlation and Predictive Values in H.264 (움직임 방향 연관 및 예측치 적용 기반 적응적 고속 H.264 움직임 추정 알고리즘의 설계)

  • Kim, Cheong-Ghil
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.10 no.2
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    • pp.53-61
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    • 2011
  • This research presents an adaptive fast motion estimation (ME) computation on the stage of uneven multi-hexagon grid search (UMHGS) algorithm included in an unsymmetrical-cross multi-hexagon-grid search (UMHexagonS) in H.264 standard. The proposed adaptive method is based on statistical analysis and previously obtained motion vectors to reduce the computational complexity of ME. For this purpose, the algorithm is decomposed into three processes: skipping, terminating, and reducing search areas. Skipping and terminating are determined by the statistical analysis of the collected minimum SAD (sum of absolute difference) and the search area is constrained by the slope of previously obtained motion vectors. Simulation results show that 13%-23% of ME time can be reduced compared with UMHexagonS, while still maintaining a reasonable PSNR (peak signal-to-noise ratio) and average bitrates.

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Block-Matching Motion Estimation : Classification and Comparison (블록 정합 방법을 이용한 움직임 추정 : 분류 및 비교)

  • Cheoi, Kyung-Joo;Lee, Yill-Byung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2000.10b
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    • pp.931-934
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    • 2000
  • 움직임 추정 및 보상을 위한 방법 중 가장 많이 사용하는 블록 정합 방법은 어떤 평가 함수와 탐색방법(Search Procedure)을 사용했느냐에 따라 그 성능이 달라지게 된다. 본 논문에서는 평가 함수로써 평균 제곱 오차(Mean Squared Error; MSE), 평균 절대값 오차(Mean Absolute Error; MAE), 화소 차분류(Pel Difference Classification: PDC)을, 탐색 방법으로써 전체 탐색 방법(Full Search Method : FSM), 3단계 탐색 방법(Three Step Search : TSS), 대각 탐색 방법(Cross Search Algorithm ;CSA)을 사용하여 이들의 성능을 각각 비교 분석하여 봄으로써 블록 정합 방법을 이용한 움직임 추정에 대한 전반적인 이해를 도모하고자 한다.

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Optimum Design of Truss on Sizing and Shape with Natural Frequency Constraints and Harmony Search Algorithm (하모니 서치 알고리즘과 고유진동수 제약조건에 의한 트러스의 단면과 형상 최적설계)

  • Kim, Bong-Ik;Kown, Jung-Hyun
    • Journal of Ocean Engineering and Technology
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    • v.27 no.5
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    • pp.36-42
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    • 2013
  • We present the optimum design for the cross-sectional(sizing) and shape optimization of truss structures with natural frequency constraints. The optimum design method used in this paper employs continuous design variables and the Harmony Search Algorithm(HSA). HSA is a meta-heuristic search method for global optimization problems. In this paper, HSA uses the method of random number selection in an update process, along with penalty parameters, to construct the initial harmony memory in order to improve the fitness in the initial and update processes. In examples, 10-bar and 72-bar trusses are optimized for sizing, and 37-bar bridge type truss and 52-bar(like dome) for sizing and shape. Four typical truss optimization examples are employed to demonstrate the availability of HSA for finding the minimum weight optimum truss with multiple natural frequency constraints.

Harmony Search Algorithm-Based Approach For Discrete Size Optimization of Truss Structures

  • Lee Kang-Seok;Kim Jeong-Hee;Choi Chang-Sik;Lee Li-Hyung
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2005.04a
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    • pp.351-358
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    • 2005
  • Many methods have been developed and are in use for structural size optimization problems, In which the cross-sectional areas or sizing variables are usually assumed to be continuous. In most practical structural engineering design problems, however, the design variables are discrete. This paper proposes an efficient optimization method for structures with discrete-sized variables based on the harmony search (HS) meta-heuristic algorithm. The recently developed HS algorithm was conceptualized using the musical process of searching for a perfect state of harmony. It uses a stochastic random search instead of a gradient search so that derivative information is unnecessary In this paper, a discrete search strategy using the HS algorithm is presented in detail and its effectiveness and robustness, as compared to current discrete optimization methods, are demonstrated through a standard truss example. The numerical results reveal that the proposed method is a powerful search and design optimization tool for structures with discrete-sized members, and may yield better solutions than those obtained using current method.

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Optimization of RC polygonal cross-sections under compression and biaxial bending with QPSO

  • de Oliveira, Lucas C.;de Almeida, Felipe S.;Gomes, Herbert M.
    • Computers and Concrete
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    • v.30 no.2
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    • pp.127-141
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    • 2022
  • In this paper, a numerical procedure is proposed for achieving the minimum cost design of reinforced concrete polygonal column cross-sections under compression and biaxial bending. A methodology is developed to integrate the metaheuristic algorithm Quantum Particle Swarm Optimization (QPSO) with an algorithm for the evaluation of the strength of reinforced concrete cross-sections under combined axial load and biaxial bending, according to the design criteria of Brazilian Standard ABNT NBR 6118:2014. The objective function formulation takes into account the costs of concrete, reinforcement, and formwork. The cross-section dimensions, the number and diameter of rebar and the concrete strength are taken as discrete design variables. This methodology is applied to polygonal cross-sections, such as rectangular sections, rectangular hollow sections, and L-shaped cross-sections. To evaluate the efficiency of the methodology, the optimal solutions obtained were compared to results reported by other authors using conventional methods or alternative optimization techniques. An additional study investigates the effect on final costs for an alternative parametrization of rebar positioning on the cross-section. The proposed optimization method proved to be efficient in the search for optimal solutions, presenting consistent results that confirm the importance of using optimization techniques in the design of reinforced concrete structures.