• Advances in concrete construction
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• v.15 no.1
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• pp.41-46
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• 2023

Sport has no age limit and can be done anywhere and in any condition with minimal equipment. The existence of sports spaces in all parts of the world is considered a citizen's right. One of the activities carried out in this field is installing sports equipment and structures in parks and encouraging citizens to use this equipment for physical health with the least cost and facilities. Installing sports structures in open spaces such as parks is a practical step for developing citizens' sports. Although using devices in parks is acceptable, it is more critical to meet scientific and technical standards. The components of these structures must have high strength and endurance against changes in environmental conditions such as humidity, temperature difference, and corrosion. Among the various causes of material degradation, corrosion has always been one of several fundamental causes of metal equipment failure. Sports structures in open spaces are not safe from corrosion. Uniform corrosion is the most common type of corrosion. This corrosion usually occurs uniformly through a chemical or electrochemical reaction across the surface exposed to the corrosive environment. Rust and corrosion of outdoor sports structures are examples of this corrosion. For this reason, in this research, with the green synthesis of silica nanoparticles and its application in outdoor sports structures, the life span of these structures can be increased for the use of physical exercises as well as their quality.

• Steel and Composite Structures
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• v.46 no.3
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• pp.417-433
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• 2023

The maximum ductility and cumulative ductility of connection joints of Buckling-Restrained Braced Frames (BRBF) are critical to the structural overall performance, which should be matched with the BRB ductility. The two-story and one-span BRBF with a one-third scale was tested under cyclic quasi-static loading, and the top-flange beam splice (TFBS) rotational connections were proposed and adopted in BRBF. The deformation capacity of TFBS connections was observed during the test, and the relationship between structural global ductility and local connection ductility was studied. The rotational capacity of the beam-column connections and the stability performance of the BRBs are highly relevant to the structural overall performance. The hysteretic curves of BRBF are stable and full under large displacement demand imposed up to 2% story drift, and energy is dissipated as the large plastic deformation developed in the structural components. The BRBs acted as fuses and yielded first, and the cumulative plastic ductility (CPD) of BRBs is 972.6 of the second floor and 439.7 of the first floor, indicating the excellent energy dissipation capacity of BRBs. Structural members with good local ductility ensure the large global ductility of BRBF. The ductile capacity and hysteretic behavior of BRBF with TFBS connections were compared with those of BRBF with Reduced Beam Section (RBS) connections in terms of the experimental results.

• Annual Conference on Human and Language Technology
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• 2023.10a
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• pp.80-85
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• 2023

기계 번역에서 품질 검증은 정답 문장 없이 기계 번역 시스템에서 생성된 번역의 품질을 자동으로 추정하는 것을 목표로 한다. 일반적으로 이 작업은 상용화된 기계 번역 시스템에서 후처리 모듈 역할을 하여 사용자에게 잠재적인 번역 오류를 경고한다. 품질 검증의 하위 작업인 치명적인 오류 탐지는 번역의 오류 중에서도 정치, 경제, 사회적으로 문제를 일으킬 수 있을 만큼 심각한 오류를 찾는 것을 목표로 한다. 본 논문은 치명적인 오류의 유무를 분류하는 것을 넘어 문장에서 치명적인 오류가 존재하는 부분을 제시하기 위한 새로운 데이터셋과 모델을 제안한다. 이 데이터셋은 거대 언어 모델을 활용하는 구축 방식을 채택하여 오류의 구체적인 범위를 표시한다. 또한, 우리는 우리의 데이터를 효과적으로 활용할 수 있는 다중 작업 학습 모델을 제시하여 오류 범위 탐지에서 뛰어난 성능을 입증한다. 추가적으로 언어 모델을 활용하여 번역 오류를 삽입하는 데이터 증강 방법을 통해 보다 향상된 성능을 제시한다. 우리의 연구는 기계 번역의 품질을 향상시키고 치명적인 오류를 줄이는 실질적인 해결책을 제공할 것이다.

• Advances in aircraft and spacecraft science
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• v.10 no.5
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• pp.419-437
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• 2023

This paper presents the study of the effects of rigid-body motion simultaneously with the presence of the effects of temporal variation due to the existence of morphing speed on the aeroelastic stability of the two-stage telescopic wings, and hence this is the main novelty of this study. To this aim, Euler-Bernoulli beam theory is used to model the bending-torsional dynamics of the wing. The aerodynamic loads on the wing in an incompressible flow regime are determined by using Peters' unsteady aerodynamic model. The governing aeroelastic equations are discretized employing a finite element method based on the beam-rod model. The effects of rigid-body motion on the length-based stability of the wing are determined by checking the eigenvalues of system. The obtained results are compared with those available in the literature, and a good agreement is observed. Furthermore, the effects of different parameters of rigid-body such as the mass, radius of gyration, fuselage center of gravity distance from wing elastic axis on the aeroelastic stability are discussed. It is found that some parameters can cause unpredictable changes in the critical length and frequency. Also, paying attention to the fuselage parameters and how they affect stability is very important and will play a significant role in the design.

• Childhood Kidney Diseases
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• v.28 no.1
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• pp.8-15
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• 2024

With the rapid evolution of diagnostic tools, particularly next-generation sequencing, the identification of genetic diseases, predominantly those with pediatric-onset, has significantly advanced. However, this progress presents challenges that span from selecting appropriate tests to the final interpretation of results. This review examines various genetic testing methodologies, each with specific indications and characteristics, emphasizing the importance of selecting the appropriate genetic test in clinical practice, taking into account factors like detection range, cost, turnaround time, and specificity of the clinical diagnosis. Interpretation of variants has become more challenging, often requiring further validation and significant resource allocation. Laboratories primarily classify variants based on the American College of Medical Genetics and Genomics and the Association for Clinical Genomic Science guidelines, however, this process has limitations. This review underscores the critical role of clinicians in matching patient phenotypes with reported genes/variants and considering additional factors such as variable expressivity, disease pleiotropy, and incomplete penetrance. These considerations should be aligned with specific gene-disease characteristics and segregation results based on an extended pedigree. In conclusion, this review aims to enhance understanding of the complexities of clinical genetic testing, advocating for a multidisciplinary approach to ensure accurate diagnosis and effective management of rare genetic diseases.

• Wind and Structures
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• v.10 no.4
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• pp.367-382
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• 2007

A nonlinear numerical method was developed to assess the stability of suspension bridge catwalks under a wind load. A section model wind tunnel test was used to obtain a catwalk's aerostatic coefficients, from which the displacement-dependent wind loads were subsequently derived. The stability of a suspension bridge catwalk was analyzed on the basis of the geometric nonlinear behavior of the structure. In addition, a full model test was conducted on the catwalk, which spanned 960 m. A comparison of the displacement values between the test and the numerical simulation shows that a numerical method based on a section model test can be used to effectively and accurately evaluate the stability of a catwalk. A case study features the stability of the catwalk of the Runyang Yangtze suspension bridge, the main span of which is 1490 m. Wind can generally attack the structure from any direction. Whenever the wind comes at a yaw angle, there are six wind load components that act on the catwalk. If the yaw angle is equal to zero, the wind is normal to the catwalk (called normal wind) and the six load components are reduced to three components. Three aerostatic coefficients of the catwalk can be obtained through a section model test with traditional test equipment. However, six aerostatic coefficients of the catwalk must be acquired with the aid of special section model test equipment. A nonlinear numerical method was used study the stability of a catwalk under a yaw wind, while taking into account the six components of the displacement-dependent wind load and the geometric nonlinearity of the catwalk. The results show that when wind attacks with a slight yaw angle, the critical velocity that induces static instability of the catwalk may be lower than the critical velocity of normal wind. However, as the yaw angle of the wind becomes larger, the critical velocity increases. In the atmospheric boundary layer, the wind is turbulent and the velocity history is a random time history. The effects of turbulent wind on the stability of a catwalk are also assessed. The wind velocity fields are regarded as stationary Gaussian stochastic processes, which can be simulated by a spectral representation method. A nonlinear finite-element model set forepart and the Newmark integration method was used to calculate the wind-induced buffeting responses. The results confirm that the turbulent character of wind has little influence on the stability of the catwalk.

• Tuberculosis and Respiratory Diseases
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• v.54 no.5
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• pp.495-509
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• 2003

Background : Neutrophil-mediated inflammation is usually self-limiting, because neutrophils have a remarkably short life span. Prolonged neutrophil survival, which is caused by decreased spontaneous apoptosis, leads to persistent inflammation in sepsis. Because many inflammatory cytokines, which generate signals that delay apoptosis, are regulated by nuclear factor-${\kappa}B$ transcription factor, we hypothesized that nuclear factor-${\kappa}B$ might be related to the reduced neutrophil apoptosis observed in sepsis. Methods : Neutrophils of healthy volunteers and sepsis patients were freshly isolated from venous blood. Neutrophil apoptosis was assayed with two approaches : by counting apoptotic cells under a microscope and by flow cytometry using Annexin V. The activity of nuclear factor-${\kappa}B$ was assessed by immunofluorescent staining or electrophoretic mobility shift assay. Expression of X-linked inhibitor of apoptosis was measured by western blot assay. Results : We confirmed reduced spontaneous neutrophil apoptosis in patients with sepsis. The number of apoptotic neutrophils in patients with sepsis increased to the level of that in healthy controls after cycloheximide treatment, suggesting that decreased spontaneous neutrophil apoptosis is dependent on de novo protein synthesis. In patients with sepsis, basal neutrophil nuclear factor-${\kappa}B$ was activated compared to the level in healthy controls. Moreover, a blockade of nuclear factor-${\kappa}B$ activity reversed the decreased spontaneous neutrophil apoptosis in sepsis patients. Meanwhile, X-linked inhibition of apoptosis expression, which is regulated by nuclear factor-${\kappa}B$, decreased 24 hours after incubation in healthy persons, but persisted for 24 hours in patients with sepsis. Conclusion : These observations suggest that the reduced spontaneous neutrophil apoptosis observed in patients with sepsis may be related to the induction of survival protein by nuclear factor-${\kappa}B$.

• Earthquakes and Structures
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• v.19 no.1
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• pp.29-44
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• 2020

The effectiveness and the sensitivity of a Wireless impedance/Admittance Monitoring System (WiAMS) for the prompt damage diagnosis of two single-storey single-span Reinforced Concrete (RC) frames under cyclic loading is experimentally investigated. The geometrical and the reinforcement characteristics of the RC structural members of the frames represent typical old RC frame structure without consideration of seismic design criteria. The columns of the frames are vulnerable to shear failure under lateral load due to their low height-to-depth ratio and insufficient transverse reinforcement. The proposed Structural Health Monitoring (SHM) system comprises of specially manufactured autonomous portable devices that acquire the in-situ voltage frequency responses of a network of twenty piezoelectric transducers mounted to the RC frames. Measurements of external and internal small-sized piezoelectric patches are utilized for damage localization and assessment at various and increased damage levels as the magnitude of the imposed lateral cycle deformations increases. A bare RC frame and a strengthened one using a pair of steel crossed tension-ties (X-bracing) have been tested in order to check the sensitivity of the developed WiAMS in different structural conditions since crack propagation, damage locations and failure mode of the examined frames vary. Indeed, the imposed loading caused brittle shear failure to the column of the bare frame and the formation of plastic hinges at the beam ends of the X-braced frame. Test results highlighted the ability of the proposed SHM to identify incipient damages due to concrete cracking and steel yielding since promising early indication of the forthcoming critical failures before any visible sign has been obtained.

• Advances in concrete construction
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• v.9 no.3
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• pp.235-248
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• 2020

Progressive collapse in a structure occurs when load bearing members are failed and the adjoining structural elements cannot resist the redistributed forces and fails subsequently, that leads to complete collapse of structure. Recently, construction using precast concrete technology is adopted increasingly because it offers many advantages like faster construction, less requirement of skilled labours at site, reduced formwork and scaffolding, massive production with reduced amount of construction waste, better quality and better surface finishing as compared to conventional reinforced concrete construction. Connections are the critical elements for any precast structure, because in past, major collapse of precast structure took place because of connection failure. In this study, behavior of four different precast wet connections with U shaped reinforcement bars provided at different locations is evaluated. Reduced 1/3^rd scale precast beam column assemblies having two span beam and three columns with removed middle column are constructed and examined by performing experiments. The response of precast connections is compared with monolithic connection, under column removal scenario. The connection region of test specimens are filled by cast-in-place micro concrete with and without polypropylene fibers. Performance of specimen is evaluated on the basis of ultimate load carrying capacity, maximum deflection at the location of removed middle column, crack formation and failure propagation. Further, Finite element (FE) analysis is carried out for validation of experimental studies and understanding the performance of structural components. Monolithic and precast beam column assemblies are modeled using non-linear Finite Element (FE) analysis based software ABAQUS. Actual experimental conditions are simulated using appropriate boundary and loading conditions. Finite Element simulation results in terms of load versus deflection are compared with that of experimental study. The nonlinear FE analysis results shows good agreement with experimental results.

• Journal of the Korea Society for Simulation
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• v.16 no.4
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• pp.77-86
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• 2007

Web services are considered as the critical component in the business plans of corporations as they offers the potential for creating highly dynamic and versatile distributed applications that span across business boundaries. Web Service Orchestration studies composition of already-existing web services to create new value-added services. The composite web services could be executed in a centralized or peer-to-peer(P2P) orchestration model. Compared with centralized-orchestration model, the P2P-based orchestration model provides better scalability, reliability, and performance for the overall services. However, recent P2P-orchestration solutions have limitation in supporting complex workflow patterns. Therefore, they could not effectively handle sophisticated business workflow, which contains complex workflow patterns. In this paper, we propose the WORKGLOW system, which can deal with complex workflow patterns while it is able to perform composite services in P2P orchestration manner. Comparing with centralized orchestration systems, the WORKGLOW brings up more business logic advantages, better performance, and higher flexibility with only a little overhead.