• Toxicological Research
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• v.11 no.1
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• pp.1-8
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• 1995

Fumonisins are a family of mycotoxins produced by the fungus Fusarium moniliforme which is a common contaminant in corn. Fumonisins are potent inhibitors of sphingosine and sphinganine N-acyltransferase (ceramide synthase), key enzymes in sphingolipid metabolism. The purpose of this study was to provide the evidence that the elevated levels of free sphingoid bases (primarily sphinganine) and depletion of complex sphingolipids were closely related to the inhibition of cell growth in LLC-$PK_1$ cells exposed to fumonisin $B_1$$(\leq 35 {\mu}M)$. Concentrations of fumonisin $B_1$ between 10 and $35 {\mu}M$ were known to inhibit cell growth without cytotoxicity in $LLC-PK_1$ cells (Yoo et al. Toxicol. Appl. Pharmacol. 114, 9-15, 1992). Cells exposed to 35$\mu M$ fumonisin B$_1$ for 48 and 72 hr developed a fibroblast-like (elongated and spindle-shaped) appearance and were less confluent than normal cells. At between 24 and 48 hr after exposure to fumonisin $B_1$ cells were beginning to show the inhibition of cell growth and at 72 hr the number of viable cells in fumonisin-treated cultures was about 50% of concurrent control cultures. During the 24 hr lag period preceding inhibition of cell growth, the free sphinganine levels in cells exposed to $35 {\mu}M$ fumonisin $B_1$ were highly elevated (approximately 230 fold higher than normal cells). The elevated levels of free sphinganine were $435\pm14$$pmoles/{10^6}$ cells at 48 hr and approximately TEX>$333\pm11$$pmoles/{10^6}$ cells in cells exposed to $35{\mu}M$ fumonisin$B_1$ at 72 hr, while the levels of free sphinganine in normal cells were less than 2$pmoles/{10^6}$ cells. Under the same condition, depletion of intracellular complex sphingolipids as a consequence of fumonisin inhibition of de novo sphingolipid biosynthesis and turnover pathway was appeared. Content of free sphingold bases in dividing cells was more elevated than in confluent cells at 24-48 hr after cells were exposed to $20{\mu}M$ fumonisin $B_1$. The dividing cells were showing the inhibition of cell growth at 48-72 hr and $20{\mu}M$ fumonisin $B_1$. The results of this study support the hypothesis that the inhibition of cell growth is very well related to the disruption of sphingolipid metabolism in $LLC-PK_1$ cells.

• Journal of Preventive Medicine and Public Health
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• v.30 no.1 s.56
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• pp.209-228
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• 1997

In ordo to investigate the professional job perception and job satisfaction of interns and residents and its related factors, the author conducted survey using self administered questionnaire for 2 months(August and September, 1996). The study subjects were 562 interns and residents who worked at one university hospital(tertiary hospital) and two general hospitals(secondary hospital) in Taegu, Korea. Among them, 297 (52.8%) responded completely. The results were as follows ; Respondents thought that people component was most important, science and status components were next among professional value scales which meant the desirable attitudes required to conduct professional works. But, the score of professional value scales was generally high and not affected by other variables in multiple linear regression analysis. They seemed to have very normative and ideal perceptions about professional values. The score of professionalism scales, which were attitudinal and behavioral traits about professional job, of high grade residents was significantly higher than that of interns and lower grade residents. The score of reference to professional organization and autonomy factor were increasing significantly as the grade increased. Working conditions and perception for socioeconomic status of doctors influenced the score of professionalism scale significantly. It seemed that professional socialization was made during the training periods of interns and residents. Most of respondents answered that current socioeconomic status of doctors were middle and high strata but they responded that the socioeconomic status of doctors would fall in the future. They seemed to have a pessimistic thought about doctor's status. Generally the respondents thought that they were satisfied with doctor job and fit to the job, but 51.9% answered that if possible they would get other jobs. It seemed to reflect their critical thinking on doctors' status. Perceptions about socioeconomic status of doctors, professional value and professionalism influenced job satisfaction significantly. The interns and residents had high sense of calling to doctors and thought that doctors were socially important job. Generally they were satisfied with their job. Interns and residents had normative thoughts about the trait which compentent doctors must have. During the training period, they seemed to have attitude and perception as a professional and to make professional socializations.

• Journal of the Korean Vacuum Society
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• v.15 no.1
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• pp.81-88
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• 2006

Laterally self-aligned InGaAs/GaAs quantum-dots (QDs) have been fabricated by using a multilayer stacking technique. For the growth optimization, we vary the number of stacks and the growth temperature in the ranges of 1-15 periods and $500-540^{\circ}C$. respectively, Atomic force microscope (AFM) images and photoluminescence (PL) spectra reveal that the lateral alignment of QDs is enhanced in extended length by an increased stack period, but severely degrades into film-like wires above a critical growth temperature. The morphological and the photoluminescence characteristics of laterally self-aligned InGaAs QDs have been analyzed through mutual comparisons among four samples with different parameters. An anisotropic arrangement develops with increasing number of stacks, and high-temperature capping allows isolated QDs to be spontaneously organized into a one-dimensionally aligned chain-like shape over a few ${\mu}m$, Moreover, the migration time allowed by growth interruption plays an additional important role in the chain arrangement of QDs. The QD chains capped at high temperature exhibit blue shifts in the emission energy, which may be attributed to a slight outdiffusion of In from the InGaAs QDs.

• Journal of Korea Water Resources Association
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• v.45 no.5
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• pp.445-454
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• 2012

The present study aims to investigate the long-term channel morphological changes derived from channelization, embankment and levee construction works in unregulated fluvial channel of the Jiseock River. Analyses of aerial photographs taken past (Year 1966) and recent (Year 2002) showed the temporally remarkable changes in channel planform such as channel shape, bar migration, vegetation encroachment in bar. During the period, the natural single threading changed into braided types together with decreasing sinuosity by 9.2%, increasing vegetation occupied bar ranged 97% of total bars area. Because such channel morphological changes are closely similar to those in dam downstream channels, we assume that both/either flow regime alteration and/or sediment transport discontinuity may be critical for the fixed channel and spread of vegetated bars even in unregulated river without dam reservoir upstream. We found more reduced frequency and magnitude of flooding water level comparing with past, but no significant alteration of inter annual water level variation. Bed material has been coarsened by 4~5 times and the riverbed has been degraded in overall channel but aggraded locally in conjunction reach of tributaries. The results indicates that reduced sediment dynamics in fluvial channel which derived by bed material coarsening, river bed degradation and unbalanced sediment transport capacity between tributary and mainstem can be a causal factor to trigger channel morphological changes even in unregulated rivers.

• Journal of Korea Water Resources Association
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• v.45 no.8
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• pp.839-851
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• 2012

When we evaluate the water supply capacity of a river basin, it is a common practice to gradually increase the water demand and check if the water demands are met. This practice is not only used in the simulation approach, but also in the optimization approach. However, this trial and error approach is a tedious task. Hence, we propose a two-phase method. In the first phase, by assuming that the decision maker has complete information on inflow data, we use a goal programming model that can generate the maximum water supply capacity at one time. In the second phase, we simulate the real-time operation for the critical period by utilizing the water supply capacity given by the goal programming model under the condition that there is no foresight of inflow. We applied the two-phase method to the Geum-River basin, where multi-purpose weirs were newly constructed. By comparing the results of the goal programming model with those of the real-time simulation model we could comprehend and estimate the effect of perfect inflow data on the water supply capacity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.78-85
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• 2020

The scaffolding system, which is a construction workbench of the cargo containment for a membrane LNG carrier, is a large truss structure composed of various members. To shorten the installation period and process of the scaffolding system, it is effective to enlarge the mounting unit from the existing two stages to eight stages. Owing to the increase in lifting load according to the large size of the module, the stresses around the pin and hole will be increased significantly. In this study, a tensile strength test and contact stress analysis were performed to confirm the structural safety. The relatively large hole deformation was observed visually near the average load generated in the vertical pipe at the top through tensile strength tests. A contact stress calculation confirmed the stress distribution around the hole. The contact problem was dealt with in terms of the Herzian contact stress. The possibility of 8-stage loading was examined by comparing the yield strength and contact stresses of failure critical locations. As a result, the 8-stage loading method of the existing scaffolding material was inadequate, and a new loading method with proper safety is proposed.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.16 no.2
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• pp.81-89
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• 2002

The Battery Energy Storage System (BESS) has lots of advantages such as load leveling, quick response emergency power (spinning reserve), frequency and voltage control, improvement of reliability, and deferred generation and transmission construction. However, it is very critical that economic feasibility requires justification from the customer side of meter to promoting the dissemination of BESS in nation widely. In this paper, we proposed the economic assessment model of customer owned BESS which is complemented and improved the existing model. The proposed model is applied to the typical customer types, i.e. light industrial, commercial, and residential, which are taken from the statistical analysis on the load profile survey of Korea Electric Power COmpany (KEPCO). The economic viability performed for each customer load type to justifying their economic feasibility of BESS installation from the economic measures such as payback period, Net Present Worth (NPW), Rate Of Return (ROR). The results show that the BESS has economic benefits to the specific customer type, i.e. residential customer. Therefore, the government and the energy agency should be committing the support program, such as tax incentive, financial support, to disseminate the BESS nation widely. The results of this paper are useful to the customer investment decision-making and the national energy policy & strategy in Korea.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.31 no.4
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• pp.447-453
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• 1986

Germination and seedling elongation of soybeans [cult. ‘Williams’] were measured at two temperatures (15 and 3$0^{\circ}C$), three seed water contents (30, 50, and 70%), and with and without polyethylene glycol-8000 (PEG) treatments. A split-plot design was used with four replications. Observations were made from two hours to eight days for each treatment combination. Seeds were soaked with 30% PEG solution with 0.2% thiram at 15 C for six days, rinsed with deionized water and dried at 25.5$^{\circ}C$ for three days. Ten treated or untreated seeds were placed on Whatman No. I (9 cm) filter paper in plastic petridishes to which sufficient deionized water was added to adjust seed moisture content to the desired level. The dishes were then sealed with parafilm and placed in a continuous programmed temperature chamber under dark condition. Seedling growth did not occur at either temperature when moisture content was 50 percent or less. Osmo-conditioning with PEG showed positive effects on seedling moisture uptake and seedling growth at 15$^{\circ}C$ but little effect at 3$0^{\circ}C$. Seedling moisture content increased rapidly early in the germination period and reached 60% at 15 C for 56 hours and at 3$0^{\circ}C$ for 28 hours. Seedling growth started when seed moisture reached a critical point of 60% at 15$^{\circ}C$, however, growth started after 20 hours of germination at 3$0^{\circ}C$. Seedlings of soybeans elongated more than four times faster at 3$0^{\circ}C$ than at 15$^{\circ}C$. Water uptake during germination was characterized by two phases in this experiment.

• Economic and Environmental Geology
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• v.36 no.2
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• pp.141-148
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• 2003

We investigated the distribution of sea ice using various microwave remote sensing techniques including radar altimeter, radiometer, and scatterometer data in the part of Drake passage, Antarctica, between the area 45$^{\circ}$-75$^{\circ}$W and 55$^{\circ}$-66$^{\circ}$S. Topex/poseidon radar altimeter data were used to analyze the monthly distribution of sea ice surface area between 1992 and 1999 by using Geo_bad_1 flag or MGDR. From satellite radiometer measurements of DMSP's SSM/I, sea ice concentration was extracted during the period from 1993 to 1996. To select a value of ice concentration, normally ranging from 0 to 100%, that can be used as a critical value of judging the existence for ice, sea ice areas estimated from various ice concentrations of radiometer measurements were correlated with the area estimated from the radar altimeter measurements. As a result, 20% of ice concentration was selected, and, then this value was used to integrate radiometer data with radar altimeter and ERS-1/2 scatterometer data. To indirectly verify the result, the last 20 year's sea ice concentration was correlated with surface temperature data near Esper-anza Observation Station. The two data showed a high correlation coefficient of 0.86. The amount of sea ice and temperature variation were found to be closely related in the study area, and this indirectly verifies the result of this study. We provided a method to judge the existence of sea ice from ice concentration of satellite radiometer data and suggested a method to monitor more detailed temporal and spatial variation of sea ice distribution by integra-tion of various microwave remote sensing techniques.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.3
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• pp.152-158
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• 2015

This paper investigated the membrane fouling potential at the state of passive adsorption which is no permeation with the test modules on COD (Chemical oxygen demand) loading rates, examined the recovery rate and resistance on membrane fouling by three cleaning manners of hydrophobic membrane in a bioreactor. The results showed that high COD loading led to the increase of extra-cellular polymeric substances and filtration resistance. The permeability resistance from 1st day to 63rd day was getting increased, however, the value of permeability resistance after 63th day during the operation period was almost same level at three COD loading rates, it was due that the biomass adhesion on membrane surface at the state of passive adsorption reached to the critical state. Also, the final recovery rates after three cleaning manners were 78%, 72% and 69% at the COD loading concentrations of 250 mg/L, 500 mg/L and 750 mg/L respectively, and then recovery rate by physical cleaning at Run 2 and Run 3 was decreased after 40th day, it proved that biomass cake, which is not easily removed, was formed on the membrane surface because of high COD loading rate and EPS concentration.