• Title/Summary/Keyword: Critical factor

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The Study on critical Value of Kinematical Evaluation Variables of Lower Extremity Pronation in Biomechanical Evaluation of Running Shoes (운동화의 생체역학적 평가시 하지 회내운동의 운동학적 평가변인에 대한 상해 기준치 연구)

  • Kwak, Chang-Soo;Jeon, Min-Ju;Kwon, Oh-Bok
    • Korean Journal of Applied Biomechanics
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    • v.16 no.4
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    • pp.175-187
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    • 2006
  • The purpose of this study was to find the relationship between Achilles tendon angle, angular velocity from 2D cinematography utilized to easily analyze the functions of shoes, ankle joint moment, knee joint moment, and hip joint moment from 3D cinematography utilized to predict the injury. Also, this study was to provide the optimal standard to analyze the injury related to the shoes. Subjects in this study were 30 university male students and 18 conditions (2 types of running speed, 3 of midsole hardness, 3 of midsole height) were measured using cinematography and force platform. The results were as following. 1) Hip joint abduction moment was effected by many variables such as running speed, midsole height, maximum achilles tendon angle, ground reaction force. 2) Knee joint rotational moment in running was approximately 1/10 - 1/4 times of the injury critical value and eversion moment was approximately 1/4 - 1/2 times of the injury critical value. 3) Ankle joint pronation moment in running was 1/3 - 1/2 times of the injury critical value. 4) Knee joint rotational moment was found to be irrelevant with maximum achilles tendon angle or angular velocity. 5) Pronation from running was thought to be relevant to rather eversion moment activity than rotational moment activity of knee joint. 6) Plantar flexion abductor of ankle showed significant relationship with the ground reaction force variable. 7) When the loading rate for ground reaction force in passive region increased, extensor tended to be exposed to the injury. Main variables in biomechanical analysis of shoes were impact absorption and pronation. Among these variables, pronation factor was reported to be relevant with knee injury from long duration exercise. Achilles tendon angle factor was utilized frequently to evaluate this. However, as the results of this study showed, the relationship between these variables and injury relating variable of knee moment was so important. Studies without consideration on this finding should be reconsidered and reconfirmed.

Co-evolutionary Structural Design Framework: Min(Volume Minimization)-Max(Critical Load) MDO Problem of Topology Design under Uncertainty (구조-하중 설계를 고려한 공진화 구조 설계시스템)

  • 양영순;유원선;김봉재
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.16 no.3
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    • pp.281-290
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    • 2003
  • Co Evolutionary Structural Design(CESD) Framework is presented, which can deal with the load design and structural topology design simultaneously. The load design here is the exploration algorithm that finds the critical load patterns of the given structure. In general, the load pattern is a crucial factor in determining the structural topology and being selected from the experts어 intuition and experience. However, if any of the critical load patterns would be excluded during the process of problem formation, the solution structure might show inadequate performance under the load pattern. Otherwise if some reinforcement method such as safety factor method would be utilized, the solution structure could result in inefficient conservativeness. On the other hand, the CESD has the ability of automatically finding the most critical load patterns and can help the structural solution evolve into the robust design. The CESD is made up of a load design discipline and a structural topology design discipline both of which have the fully coupled relation each other. This coupling is resolved iteratively until the resultant solution can resist against all the possible load patterns and both disciplines evolve into the solution structure with the mutual help or competition. To verify the usefulness of this approach, the 10 bar truss and the jacket type offshore structure are presented. SORA(Sequential Optimization & Reliability Assessment) is adopted in CESD as a probabilistic optimization methodology, and its usefulness in decreasing the computational cost is verified also.

Effect of lamination pressing force for stiffness variation of a laminated rotor (적층로터의 강성 변경을 위한 적층판 압착력의 영향)

  • 김영춘;박희주;김경웅
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.788-792
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    • 2003
  • Rotating machines are widely used in industrial world and especially motor and generator take up much part of it. As for this kind of motor and generator, electrical loss due to eddy current is the very important factor and that is also a primary factor causes heat generation. To solve this kind of problem like the above. insulated laminating silicon steel sheet is used to prevent eddy current effect. Laminated rotor is widely used as rotating shaft of motor and generator. Due to that, electrical loss and heat problem can be solved but designer meets another problem. In general. most of the motor and generator can be normally operated under 3,600 rpm because they are designed to have the first critical speed more than that speed. But nowadays, they should be operated more than the first critical speed as usual with the trend of high speed, large scale and high precision in industrial world. The critical speed can be determined from the inertia and stillness for the rotor and bearing of rotating systems. The laminated rotor stiffness can be hardly determined because it can be derived a lot factors for instance rotor material and shape, lamination material and shape, insulation material. lamination force and so on. In this paper, the change of the natural frequency of the motor was examined with the change of the lamination force as an experimental method and design criteria will be presented for motor & generator designer, who can apply the result of numerical analysis with equivalent diameter scheme with ease.

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Dynamic Fracture Properties of Nylon Thermoplastic Material Depending on Notch Angle with Charpy Impact Machine and Finite Element Method (유한요소법과 샤피충격시험기에 의한 노치각도에 따른 나일론 열가소성 플라스틱 재료의 파괴특성)

  • Park, Myung-Kyun;Lee, Jung-Won;Kim, Tae-Ok
    • Journal of the Korean Institute of Gas
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    • v.12 no.1
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    • pp.1-6
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    • 2008
  • The notched Charpy impact test is one of the most prevalent techniques used to characterize the effect of high impulse loads on polymeric materials. In this study, a method of analysis in nylon plastic materials is suggested to evaluate the critical strain energy release rate for variation of notch angles from the Charpy impact energy measurement. Instrumented Charpy impact tester was used to extract ancillary information concerning fracture parameters in addition to total fracture properties and maximum critical load. The dynamic stress intensity factor of nylon plastic material was calculated for the ASTM Charpy specimen from the obtained maximum critical load. Also, the finite element model was developed to figure out the stress distributions for Charpy specimen with different notch angles subject to 3 point bending load which is equivalent to the load applied in the experiment.

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Pemetrexed Continuation Maintenance versus Conventional Platinum-Based Doublet Chemotherapy in EGFR-Negative Lung Adenocarcinoma: Retrospective Analysis

  • Paik, Seung Sook;Hwang, In Kyoung;Park, Myung Jae;Lee, Seung Hyeun
    • Tuberculosis and Respiratory Diseases
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    • v.81 no.2
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    • pp.148-155
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    • 2018
  • Background: Although targeted therapy and immuno-oncology have shifted the treatment paradigm for lung cancer, platinum-based combination is still the standard of care for advanced non-small cell lung cancer (NSCLC). Pemetrexed continuation maintenance therapy has been approved and increasingly used for patients with nonsquamous NSCLC. However, the efficacy of this strategy has not been proven in patients without driving mutations. The objective of this study was to compare the clinical benefit of pemetrexed continuation maintenance to conventional platinum-based doublet in epidermal growth factor receptor (EGFR)-negative lung adenocarcinoma. Methods: A total of 114 patients with EGFR-negative lung adenocarcinoma who were treated with platinum doublet were retrospectively enrolled. We compared the survival rates between patients received pemetrexed maintenance after four-cycled pemetrexed/cisplatin and those received at least four-cycled platinum doublet without maintenance chemotherapy as a first-line treatment. Results: Forty-one patients received pemetrexed maintenance and 73 received conventional platinum doublet. Median progression-free survival (PFS), which was defined as the time from the day of response evaluation after four cycles of chemotherapy to disease progression or death, was significantly higher in the pemetrexed maintenance group compared to conventional group (5.8 months vs. 2.2 months, p<0.001). Median overall survival showed an increasing trend in the pemetrexed maintenance group (22.3 months vs. 16.1 months, p=0.098). Multivariate analyses showed that pemetrexed maintenance chemotherapy was associated with better PFS (hazard ratio, 0.73; 95% confidence interval, 0.15-0.87). Conclusion: Compared to conventional platinum-based chemotherapy, premetrexed continuation maintenance treatment is associated with better clinical outcome for the patients with EGFR wild-type lung adenocarcinoma.

Estimation of fracture toughness of cast steel container from Charpy impact test data

  • Bellahcenea, Tassadit;Aberkane, Meziane
    • Steel and Composite Structures
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    • v.25 no.6
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    • pp.639-648
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    • 2017
  • Fracture energy values KV have been measured on cast steel, used in the container manufacture, by instrumented Charpy impact testing. This material has a large ductility on the upper transition region at $+20^{\circ}C$ and a ductile tearing with an expended plasticity before a brittle fracture on the lower transition region at $-20^{\circ}C$. To assess the fracture toughness of this material we use, the $K_{IC}$-KV correlations to measure the critical stress intensity factor $K_{IC}$ on the lower transition region and the dynamic force - displacement curves to measure the critical fracture toughness $J{\rho}_C$, the essential work of fracture ${\Gamma}_e$ on the upper transition region. It is found, using the $K_{IC}$-KV correlations, that the critical stress intensity factor $K_{IC}$ remains significant, on the lower transition region, which indicating that our testing material preserves his ductility at low temperature and it is apt to be used as a container's material. It is, also, found that the $J_{\rho}-{\rho}$ energetic criterion, used on the upper transition region, gives a good evaluation of the fracture toughness closest to those found in the literature. Finally, we show, by using the ${\Gamma}_e-K_{IC}$ relation, on the lower transition region, that the essential work of fracture is not suitable for the toughness measurement because the strong scatter of the experimental data. To complete this study by a numerical approach we used the ANSYS code to determine the critical fracture toughness $J_{ANSYS}$ on the upper transition region.

Factors Influencing Internet Media Credibility among College Students (대학생들의 인터넷 미디어 신뢰도에 영향을 미치는 요인 고찰 - 미디어 리터러시 역량을 중심으로)

  • Kim, Yon-Jong;Ahn, Jung-Im
    • The Journal of the Korea Contents Association
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    • v.19 no.2
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    • pp.438-449
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    • 2019
  • This study explored the perception of internet media credibility and influencing factors among college students who are routine users of internet-based media. Media literacy competences are of primary interest among others in that users' media literacy such as information evaluation, critical understanding of media, and information sharing are assumed to be related to media credibility. The results of analysis revealed critical understanding ability to be statistically significant and consistently influencing factor. Users with more critical view on media ownership, represented reality, commercial intention of media seemed less likely to trust internet media. Whereas media use motive for information was found to be a strong predicting factor, motive for pleasure showed no relationship with credibility. Based on the findings, suggestions for new research and limitations of the study were discussed.

The Deduction of the Success Factor in Construction Projects by Design Build Methods (디자인 빌드(Design Build) 방식 건설 프로젝트의 성공요인 분석에 관한 연구 - 중.소규모 건설 프로젝트를 중심으로)

  • Lee, Chi-Joo;Kim, Sang-Ki;Kim, Jae-Jun
    • Korean Journal of Construction Engineering and Management
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    • v.8 no.5
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    • pp.182-190
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    • 2007
  • The minor construction companies in Korea have grown in focusing on the construction operation field. Also, soft field is vulnerable area, and there are not enough delivery systems, therefore, a capacity of the construction industry expansion and productivity is insufficient. Furthermore, the minor construction companies are losing their areas, because the major construction companies having numerous know-how and ample funds are competitive. As the construction industry are more larger and complicated, the design build methods might be increased in the construction industry and the minor construction companies could have more competitive. Hence, this paper analyzes the success factor in minor construction projects by design build methods focusing on instance $company^{\circ}{\phi}s$ case and survey, and critical success factor deduction and importance degree analysis of this factor using AHP analysis. In addition, this paper gives fundamental data how to manage the construction project effectively for minor construction $companies^{\circ}{\phi}s$ expansion in near future.

Numerical study on buckling of steel web plates with openings

  • Serror, Mohammed H.;Hamed, Ahmed N.;Mourad, Sherif A.
    • Steel and Composite Structures
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    • v.22 no.6
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    • pp.1417-1443
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    • 2016
  • Cellular and castellated steel beams are used to obtain higher stiffness and bending capacity using the same weight of steel. In addition, the beam openings may be used as a pass for different mechanical fixtures such as ducts and pipes. The aim of this study is to investigate the effect of different parameters on both elastic and inelastic critical buckling stresses of steel web plates with openings. These parameters are plate aspect ratio; opening shape (circular or rectangular); end distance to the first opening; opening spacing; opening size; plate slenderness ratio; steel grade; and initial web imperfection. The web/flange interaction has been simplified by web edge restraints representing simply supported boundary conditions. A numerical parametric study has been performed through linear and nonlinear finite element (FE) models, where the FE results have been verified against both experimental and numerical results in the literature. The web plates are subject to in-plane linearly varying compression with different loading patterns, ranging from uniform compression to pure bending. A buckling stress modification factor (${\beta}$-factor) has been introduced as a ratio of buckling stress of web plate with openings to buckling stress of the corresponding solid web plate. The variation of ${\beta}$-factor against the aforementioned parameters has been reported. Furthermore, the critical plate slenderness ratio separating elastic buckling and yielding has been identified and discussed for two steel grades of DIN-17100, namely: ST-37/2 and ST-52/3. The FE results revealed that the minimum ${\beta}$-factor is 0.9 for web plates under uniform compression and 0.7 for those under both compression and tension.

Drosophila GAGA factor-FACT Complex and its Role in Hox Gene Expression

  • Nakayama, Takahiro;Shimojima, Tsukasa;Okada, Masahiro;Ueda, Hitoshi;Hirose, Susumu
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.10a
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    • pp.19-22
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    • 2003
  • Chromatin structure plays a critical role in the regulation of transcription. Drosophila GAGA factor directs chromatin remodeling to its binding sites. We found that Drosaphiia FACT, a heterodimer of dSPT16 and dSSRPl, is associated with GAGA factor through its dSSRPl subunit, binds to a nucleosome and facilitates GAGA factor-directed chromatin remodeling. Immunostaining of polytene chromosomes revealed colocalization of GAGA factor and FACT in many specific loci. (omitted)

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