• Journal of Microbiology
• /
• v.43 no.spc1
• /
• pp.110-117
• /
• 2005

Salmonella enterica serovar Typhimurium causes human gastroenteritis and a systemic typhoid-like infection in mice. A critical virulence determinant of Salmonella is the ability to invade mammalian cells. The expression of genes required for invasion is tightly regulated by environmental conditions and a variety of regulatory genes. The hilA regulator encodes an OmpR/ToxR family transcriptional regulator that activates the expression of invasion genes in response to both environmental and genetic regulatory factors. Work from several laboratories has highlighted that regulation of hilA expression is a key point for controlling expression of the invasive phenotype. A number of positive regulators of hilA expression have been identified including csrAB, sirA/barA, pstS, hilC/sirC/sprA, fis, and hilD. HilD, an AraC/XylS type transcriptional regulator, is of particular importance as a mutation in hilD results in a 14-fold decrease in chromosomal hilA::Tn5lacZY-080 expression and a 53-fold decrease in invasion of HEp-2 cells. It is believed that HilD directly regulates hilA expression as it has been shown to bind to hilA promoter sequences. In addition, our research group, and others, have identified genes (hilE, hha, pag, and lon) that negatively affect hilA transcription. HilE appears to be an important Salmonella-specific regulator that plays a critical role in inactivating hilA expression. Recent work in our lab has been directed at understanding how environmental signals that affect hilA expression may be processed through a hilE pathway to modulate expression of hilA and the invasive phenotype. The current understanding of this complex regulatory system is reviewed.

• Journal of Information Technology Applications and Management
• /
• v.20 no.1
• /
• pp.43-51
• /
• 2013

Human being does work to live out and they have their private life because human has sociality. Both work and life are important to live out but they are on the trade-off relationship. Because keeping the balance between work and life is too hard, it has been interested by academic and practical areas. Definition of Work-life balance here is that balance or imbalance arising between work and life has no negative impact on their daily life. Above all, Work-life balance is important because it is strongly related to identity. Recently, the introduction of the mobile office system has emerged as a way to solve the problem of work-life balance. It is based on the teleworking which was formerly generated. Teleworking is to perform the work in the employee's home or office space set aside without going into the workplace. Concept of the mobile office system here is not only using portable devices during work for convenience but also the system which is designed for the performance. Thanks to the diffusion of smart devices(smart phone, tablet pc), mobile office system has been spread. Although the importance of mobile office systems is emerging, there are few researches about it. Even they mostly focus on the standpoint of performance of mobile office system. However, Quality of life is as important as the performance. As a part of Quality of Life field, Work-life balance is the closest to employee's quality of life. So this study aims to examine the effect of the use of mobile office systems on work-life balance. To do so, we try to find factors effecting Work-life balance from existing studies and then set a research model. We set the use of mobile office systems as independent variables which are divided by use of function, use by location and use by situation. There are four dependent variables - sense of self command, sense of balance, solving work problem, solving life problem. We collected data from employees who are using mobile office systems on their job. 215 people were participated in the survey and we used multiple regression analysis to verify our research model. Results show that every independent variable has no impact on solving work problem while they have slight impact on the other dependent variables. Especially use on the business trip has significant effect on dependent variables. It means that there is a possibility use of mobile office system could control the employee's quality of life and system should be evolved until it covers even critical tasks. Also, support for mobile office system -education, encouragement-should be provided. By mobile office system is maturing, future research would be done.

• Journal of Biosystems Engineering
• /
• v.41 no.4
• /
• pp.288-293
• /
• 2016

Purpose: The purpose of this study was to investigate the key factors in designing a three-wheeled two-row soybean reaper (riding type) that is suitable for soybean production, and ensure worker safety by proposing optimal work conditions for the prototype of the designed machine in relation to the slope of the road. Methods: A three-wheeled two-row soybean reaper (riding type) was designed and its prototype was fabricated based on the local soybean-production approach. This approach was considered to be closely related to the prototype-designing of the cutter and the wheel driving system of the reaper. Load distribution on the wheels of the prototype, its minimum turning radius, static lateral overturning angle, tilt angle during driving, and The working and rear overturning (back flip) angle were measured. Based on the gathered information, investigations were conducted regarding optimal work conditions for the prototype. The investigations took into account driving stability and worker safety. Results: The minimum ground clearance of the prototype was 0.5 m. The blade height of the prototype was adjusted such that the cutter was operated in line with the height of the ridges. The load distribution on the prototype's wheels was found to be 1 (front wheel: F): 1.35 (rear-left wheel: RL): 1.43 (rear-right wheel: RR). With the ratio of load distribution between the RL and RR wheels being 1: 1.05, the left-to-right lateral loads were found to be well-balanced. The minimum turning radius of the prototype was 2.0 m. Such a small turning radius was considered to be beneficial for cutting work on small-scale fields. The sliding of the prototype started at $25^{\circ}$, and its lateral overturning started at $39.3^{\circ}$. Further, the critical slope angle for the worker to drive the prototype in the direction of the contour line on an incline was found to be $12.8^{\circ}$, and the safe angle of slope for the cutting was measured to be less than $6^{\circ}$. The critical angle of slope that allowed for work was found to be $10^{\circ}$, at which point the prototype would overturn backward when given impact forces of 1,060 N on its front wheel. Conclusions: It was determined that farmers using the prototype would be able to work safely in most soybean production areas, provided that they complied with safe working conditions during driving and cutting.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.6
• /
• pp.475-484
• /
• 2020

This study investigates determinants of talent retention in textile and garment companies located in Vietnam's Binh Duong province to propose feasible actions for their sustainable development in the current context of competition on the labor market. This study uses self-completed questionnaires to collect data which are then analysed with statistical methods including scale reliability, exploratory factor analysis, and multiple linear regression. Specifically, results from an official survey of 129 people who are regarded as talents in related companies show that there are ten determinants, ranked in descending order of their importance, including: working environment; training and promotion opportunities; salary and benefits; personal loyalty; relationship with colleagues; nature of work; organizational recognition; type of ownership; relationship with superiors; and working experience. Moreover, it is also found that foreign companies are better in retaining their talents than private domestic ones. These findings suggest that, depending on their available resources, organizations need to focus on some of these factors to improve their talent retention; among them, it is critical to provide creative space or create conductive working environment by providing talents with proper tools and equipment for them to feel excited with their work and get things done in an optimal, efficient and effective manner.

• Journal of Environmental Health Sciences
• /
• v.36 no.6
• /
• pp.441-455
• /
• 2010

Researchers who work in science and engineering R&D laboratories are commonly exposed to a wide range of chemical, biological and physical hazards. They also may adopt ergonomically poor postures for long periods of time. These factors may increase the risk of adverse health outcomes in laboratory workers. Recently, there were several fatal accidents in the laboratories in universities and research institutes in Korea. Consequently, the 'Laboratory Safety Act' was enacted in 2006. However, there are concerns about the health risk associated with chronic exposures to hazards, as the management measures provided in this Act are very limited, focusing primarily on accident prevention and compensation for lab work-related accidents. In this article, the methods for assessing exposure to chemicals in laboratory environments are discussed. Also, epidemiological studies examining the association between laboratory exposure and health effects, including cancer and reproductive toxicity are extensively reviewed. Finally, the possible roles of environmental health professionals in this area are suggested, along with a list of critical research needs for properly assessing laboratory workers' exposure and risk.

• The Journal of the Korea Contents Association
• /
• v.14 no.1
• /
• pp.158-164
• /
• 2014

This study has been started by the trendy analysis of parody in post-modern dance. Creative parody is not an imitative work but provides new originality of a work of art and serves as the criticism. Since the 1960s the trend and characteristics of using parody in post-modern dance can be classified into five concepts which are the cultural diversity, the autonomous thinking ability, the aesthetic perception, the use of the mass media and the cultural relations of the critical process. In conclusion, the parody elements in post-modern dance are due to the cultural diversity, and the experimental values which are divided into the beauty of content and mode has been acted as the important factors to achieve the parody elements to new dimension.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.8
• /
• pp.577-588
• /
• 2020

The study investigates by empirical methods the effect of motivation, leadership, and organizational culture on job satisfaction, and employee performance at Wahana Resources Ltd North Seram District, Central Maluku Regency, Indonesia. This examination intends to be a critical review for academics researching the field of human resources management (HRM). The study's sample consisted of 155 employees who were selected using the Proportionate Stratified Random Sampling method. At the same time, data were collected using a questionnaire and then analyzed using the Structural Equation Modeling on Amos. The results of data analysis showed that work motivation and organizational culture had a positive and significant effect on performance, but did not significantly influence employee job satisfaction. While leadership has a substantial impact on employee job satisfaction, it does not affect performance. The results of testing the coefficient of determination show that job satisfaction is influenced for 57.4% by motivation, leadership, and culture variables, while employee performance variables are influenced for 73.5% by motivation, leadership, culture, and job satisfaction variables. Other factors outside this study influence the rest. Motivation, leadership, and organizational culture of employees need to be improved to increase job satisfaction. Invariably, if employee job satisfaction increases, employee performance will also increase.

• Safety and Health at Work
• /
• v.9 no.4
• /
• pp.427-433
• /
• 2018

Background: The purpose of this study was to identify the influence of workers' perceived workload, accident experiences, supervisors' safety leadership, and an organization's safety climate on the cognitive and emotional risk perception. Methods: Six hundred and twenty employees in a variety of manufacturing organizations were asked to complete to a questionnaire. Among them, a total of 376 employees provided valid data for analysis. To test the hypothesis, correlation analysis and hierarchical regression analysis were used. Statistical analyses were conducted using IBM SPSS program, version 23. Results: The results indicated that workload and accident experiences have a positive influence and safety leadership and safety climate have a negative influence on the cognitive and emotional risk perception. Workload, safety leadership, and the safety climate influence perceived risk more than accident experience, especially for the emotional risk perception. Conclusion: These results indicated that multilevel factors (organization, group, and individual) play a critical role in predicting individual risk perceptions. Based on these results, therefore, to reduce risk perception related with unsafe behaviors and accidents, organizations need to conduct a variety of safety programs that enhance their safety climate beyond simple safety-related education and training. Simultaneously, it needs to seek ways to promote supervisors' safety leadership behaviors (e.g., site visits, feedback, safety communication, etc.). In addition, it is necessary to adjust work speed and amount and allocate task considering employees' skill and ability to reduce the workload for reducing risk perception.

• Steel and Composite Structures
• /
• v.41 no.5
• /
• pp.625-636
• /
• 2021

This paper examines the fire performance of uninsulated and uncoated restrained steel-concrete composite beams supplemented with externally prestressed strands through advanced numerical simulation. In this work, a sequentially coupled thermo-mechanical analysis is carried out using ABAQUS. This analysis utilizes a highly nonlinear three-dimensional finite element (FE) model that is specifically developed and validated using full-sized specimens tested in a companion fire testing program. The developed FE model accounts for nonlinearities arising from geometric features and material properties, as well as complexities resulting from prestressing systems, fire conditions, and mechanical loadings. Four factors are of interest to this work including effect of restraints (axial vs. rotational), degree of stiffness of restraints, the configuration of external prestressed tendons, and magnitude of applied loading. The outcome of this analysis demonstrates how the prestressing force in the external tendons is primarily governed by the magnitude of applied loading and experienced temperature level. Interestingly, these results also show that the stiffness of axial restraints has a minor influence on the failure of restrained and prestressed steel-concrete composite beams. When the axial restraint ratio does not exceed 0.5, the critical deflection of the composite beam is lower than that of the composite beam with a restraint ratio of 1.0.

• Structural Engineering and Mechanics
• /
• v.85 no.6
• /
• pp.765-780
• /
• 2023

In this work, a novel combined logarithmic, secant and tangential 2D and quasi-3D refined higher order shear deformation theory is proposed to examine the buckling analysis of simply supported uniform functionally graded plates under uniaxial and biaxial loading. The proposed formulations contain a reduced number of variables compared to others similar solutions. The combined function employed in this study ensures automatically the zero-transverse shear stresses at the free surfaces of the structure. Various models of the material distributions are considered (linear, quadratic, cubic inverse quadratic and power-law). The differentials stability equations are derived via virtual work principle with including the stretching effect. The Navier's approach is applied to solve the governing equations which satisfying the boundary conditions. Several comparative and parametric studies are performed to illustrates the validity and efficacity of the proposed model and the various factors influencing the critical buckling load of thick FG plate.