• Tuberculosis and Respiratory Diseases
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• 제80권4호
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• pp.351-357
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• 2017

In 2011, a cluster of peripartum patients were admitted to the intensive care unit of a tertiary hospital in Seoul with signs and symptoms of severe respiratory distress of unknown etiology. Subsequent epidemiological and animal studies suggested that humidifier disinfectant (HD) might represent the source of this pathology. Epidemiological studies, animal studies, and dose-response analysis demonstrated a strong association between HD use and lung injuries. The diagnostic criteria for HD-associated lung injury (HDALI) was defined on the basis of the clinical, pathological, and radiological attributes of the patients. The clinical spectrum of HDALI appears to range from asymptomatic to full-blown acute respiratory failure, and some patients have required actual lung transplantation for survival. The overall mortality of the exposed population was not significant, although peripartum patients and children who were admitted to the intensive care unit did show high mortality rates. Persistent clinical findings such as diffuse ill-defined centrilobular nodules and restrictive lung dysfunction were observed in some of the survivors. The findings of this review emphasize the importance of assessment of the level of toxicity of chemical inhalants utilized in a home setting, as well as the need to identify and monitor afflicted individuals after inhalational injury.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권4호
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• pp.1884-1903
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• 2019

Device-to-Device (D2D) communications can provide proximity based services in the future 5G cellular networks. It allows short range communication in a limited area with the advantages of power saving, high data rate and traffic offloading. However, D2D communications may reuse the licensed channels with cellular communications and potentially result in critical interferences to nearby devices. To control the interference and improve network throughput in overlaid D2D cellular networks, a novel channel assignment approach is proposed in this paper. First, we characterize the performance of devices by using Poisson point process model. Then, we convert the throughput maximization problem into an optimal spectrum allocation problem with signal to interference plus noise ratio constraints and solve it, i.e., assigning appropriate fractions of channels to cellular communications and D2D communications. In order to mitigate the interferences between D2D devices, a cluster-based multi-channel assignment algorithm is proposed. The algorithm first cluster D2D communications into clusters to reduce the problem scale. After that, a multi-channel assignment algorithm is proposed to mitigate critical interferences among nearby devices for each D2D cluster individually. The simulation analysis conforms that the proposed algorithm can greatly increase system throughput.

• Nuclear Engineering and Technology
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• 제53권6호
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• pp.1736-1746
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• 2021

The results of full-scale numerical experiments of a hybrid thorium-containing fuel cell facility operating in a close-to-critical state due to a controlled source of fusion neutrons are discussed in this work. The facility under study was a complex consisting of two blocks. The first block was based on the concept of a high-temperature gas-cooled thorium reactor core. The second block was an axially symmetrical extended plasma generator of additional neutrons that was placed in the near-axial zone of the facility blanket. The calculated models of the blanket and the plasma generator of D-T neutrons created within the work allowed for research of the neutronic parameters of the facility in stationary and pulse-periodic operation modes. This research will make it possible to construct a safe facility and investigate the properties of thorium fuel, which can be continuously used in the epithermal spectrum of the considered hybrid fusion-fission reactor.

• 한국학교보건학회지
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• 제9권2호
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• pp.249-266
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• 1996

AIDS and the spectrum of Human Immunodeficiency Virus(HIV) infections present a monumental challenge to the health of the Korean public. In response to this special challenge, I think public education and voluntary behavior changes are the most effective measures to fight the spread of the disease. Adolescents represent a critical risk group for prevention and intervention programming. Research indicates sexually active adolescents, homosexual contact, illicit drug use are an gradually increasing. These characteristically adolescent risk-taking behaviors suggest the need for schools and communities to mobilize intervention strategies. Schools are highly efficient ways to reach a majority of young people in Korea with HIV prevention programs. These programs include substantial attention to sexual and drug use behaviors with the long term objective of a multidimensional school health program. Information resulting from risk behavior surveillance activities and guidance on school health curricula is particularly useful. What is needed for adolescents is a revamping of education to give students the critical thinking and analytic skills that allow them to apply knowledge, make decisions, and think independently. The best HIV preventive education provides young people with opportunities to learn and practice just those skills. In the early stages of HIV education were focused solely on information. Providing information is easy but unfortunately, behavior change is not that simple to activate. Information must be combined with values exploration and skilly building, including responsible decision making, negotiation, refusal, and critical thinking skills. The same knowledge, attitudes and skills needed for effective HIV prevention also prevent or reduce other risks, including other sexually transmitted diseases, unwanted pregnancies, and alcohol or other drug use. The role of other youth serving organizations in HIV prevention is also important: parental and youth involvement is needed; it's important to presidential and governament leadership is essential to prevention education; promote integrated adolescent programs, to enhance health and education sector collaboration; and of course, we need to expand research on adolescent health and engage the media in health promotion. Among these changes, a school-based systematic health education of AIDS is certainly one of the essentials.

• 한국지진공학회논문집
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• 제10권5호
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• pp.63-71
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• 2006

건축구조물의 비선형 지진응답해석에서 입력지진동은 구조물의 탄소성 지진응답을 좌우하는 중요한 요소이다. 지진동파형은 지진발생과 전파경로에 따른 여러 가지 인자에 의해 그 특성이 결정되기 때문에 구조물의 지진응답해석에서 일반성을 갖는 입력지진동을 선정하는 것은 매우 어려운 문제이다. 본 논문은 내진설계용 스펙트럼에 대응하는 인공지진동파형을 작성한 후, 작성된 인공지진동에 대한 탄소성 응답스펙트럼 특성을 분석한 것이다. 여기서 작성된 인공지진동파형은 과거의 지진에서 얻어진 기록지진동파형을 이용하여 기록지진동과 동일한 위상각을 가지며, 감쇠정수 h=5%일 때의 내진설계용 스펙트럼과 거의 일치하도록 작성되었다. 작성된 인공지진동은 원 기록지진동과 동일한 위상각을 가지며, 주기 $T=0.02{\sim}10.0sec$ 범위에서 설계용 스펙트럼과 매우 근접하게 작성되었다. 인공지진동을 입력한 1자유도계의 탄성 및 탄소성 지진응답해석을 수행하여 탄소성 응답스펙트럼 및 탄소성 응답특성을 분석하였다. 본 논문에서 작성된 인공지진동은 건축구조물의 탄소성 지진응답해석용 입력지진동으로 충분히 타당성이 있다고 사료된다.

• 한국지진공학회논문집
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• 제12권1호
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• pp.1-9
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• 2008

건축물의 지진응답해석에서 입력지진동은 구조물의 비선형 응답에 중요한 영향을 미치는 요소이다. 지진동의 특성은 표층지반의 성질과 국부적인 지반 조건에 따른 여러 가지 인자에 의해 그 특성이 결정되기 때문에 구조물의 지진응답해석에서 일반성을 갖는 입력지진동을 선정하는 것은 매우 어려운 문제이다. 본 논문은 내진설계용 스펙트럼에 적합한 인공지진동파형을 작성한 후, 작성된 인공지진동에 의한 철근콘크리트 다층 골조구조물의 탄소성 응답특성을 분석한 것이다. 여기서 작성된 인공지진동파형은 과거 비교적 큰 규모의 지진에서 얻어진 기록지진동과 동일한 위상각을 가지며, 감쇠정수 h=5%일 때의 내진설계용 스펙트럼과 거의 일치하도록 작성하였다. 입력지진동의 탄성 가속도 응답스펙트럼이 동일한반면, 각 입력지진동띄 위상특성이 다른 인공지진동을 입력하여 다자유도 골조 구조물의 지진응답을 분석하여 건축물의 내진설계용 지진동으로서 타당성을 확인하는 것이 목적이다. 본 논문에서 작성된 인공지진동은 기록지진동에 비해 지진응답치가 안정된 값을 나타내는 것을 확인할 수 있었다. 그러므로 다층 골조구조물의 비선형 지진응답해석용 입력지진동으로 타당성이 높다고 사료되며, 비선형 지진응답해석용 입력지진동의 강도를 탄성 가속도 응답스펙트럼으로 규준화 하는 것이 합리적이라고 사료된다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제8권8호
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• pp.2691-2707
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• 2014

Medium access control is critical in wireless networks for efficient spectrum utilization. In this paper, we introduce a novel collision resolution method based on the technique of known interference cancellation, and propose a new MAC protocol named as CR-MAC, in which AP tries to decode all the collided data packets by combining partial retransmissions and known interference cancellation. As the collided transmissions are fully utilized, less retransmission is required, especially in a crowded network. The NS-2simulation and MATLAB numerical results show that, under various network settings, CR-MAC performs much better than the IEEE 802.11 DCF in terms of the aggregation throughput and the expected packet delay.

• IEIE Transactions on Smart Processing and Computing
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• 제3권5호
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• pp.267-270
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• 2014

This paper presents the comparative performance of an adaptive FIR filter for a Delayed LMS algorithm. The delayed error signal was used to obtain a Delayed LMS algorithm to allow efficient pipelining for achieving a small critical path and area efficient implementation. This paper presents hardware efficient results (device utilization parameters) and power consumed. The FPGA families (Artix-7, Virtex-7, and Kintex-7) for a low voltage perspective are shown. The synthesis results showed that the artix-7 CMOS family achieves the lowest power consumption of 1.118 mW with 83.18 % device utilization. Different Precision strategies, such as the speed optimization and power optimization, were imposed to achieve these results. The algorithm was implemented using MATLAB (2013b) and synthesized on the Leonardo spectrum.

• IMMUNE NETWORK
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• 제15권4호
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• pp.191-198
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• 2015

Hepatitis B virus (HBV) is responsible for approximately 350 million chronic infections worldwide and is a leading cause of broad-spectrum liver diseases such as hepatitis, cirrhosis and liver cancer. Although it has been well established that adaptive immunity plays a critical role in viral clearance, the pathogenetic mechanisms that cause liver damage during acute and chronic HBV infection remain largely known. This review describes our current knowledge of the immune-mediated pathogenesis of HBV infection and the role of immune cells in the liver injury during hepatitis B.

• BMB Reports
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• 제30권3호
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• pp.229-233
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• 1997

Indolicidin has been known to have a broad spectrum of antimicrobial activities against Gram negative and positive bacteria. Its eight analogues were chemically synthesized. The analogue design was based on the analysis of sequence to elucidate the role of some residues in the antibacterial mechanism of indolicidin. Bactericidal activities were assayed against Escherichia coli and Proteus vulgaris, and the membrane perturbing abilities of the peptides were assayed using a dye containing liposome. Among the eight analogues, $[Gly^4, Gly^6]-Indo,\;[Ile^6,Ile^8]-Indo,\;[Lys^{12}]-Indo$ and $[Thr^2,Tyr^9]-Indo$ showed enhanced antibacterial activities. These results suggest that proline and cationic residues are important in the bactericidal activity of indolicidin. We tried to describe the antimicrobial mechanism of indolicidin with these results.