• Journal of Korean Academy of Fundamentals of Nursing
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• v.6 no.3
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• pp.477-492
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• 1999

The disease patterns among the Korean was shifted from acute and infectious diseases to chronic diseases. According to the these disease patterns trends, people have concerned about the health promotion and health behaviors. Pender's(1996) revised health promotion model(HPM) is consist of three categories; Individual characteristics and experiences, Behavior-specific cognitions and affect, behavioral outcome. Of these categories, individual characteristics and experiences, this category of variables is considered to be of biological, psychological and socio-cultural personal factors, especially, individual fatigue. Futhermore. these variables constitute a critical core for nursing intervention, as they are subject to modification through nursing actions. But there is no few the research of the relationship between the fatigue and health promotion. Therefore, the purpose of this study is to investigate the correlation between the fatigue and health promoting life style among a rural college students. Additionally, this descriptive correlational study identified the relation of demographic factors and fatigue, health promoting life style. From June 20 to 26, 1998, a convenience sample of 270 college students completed the questionnaire of the fatigue and health promoting life style profile which were developed by the Yoshitake(1978) and Walker, et al.(1987), respectively. The descriptive correlational statistics, mean, t-test, ANONA, Pearson correlation coefficient were used to analyze the data gathered with SAS pc+ program. The results were as it follows: 1. The average fatigue score of the subjects was $64.93{\pm}12.89$. Fatigue scores by subcategory were physical symptoms($23.5{\pm}4.87$). psychological symptoms($22.11{\pm}4.66$) and neuro-sensory symptoms($19.32{\pm}5.14$). With the respect to the demographic characteristics of the subjects, there were statistically significant differences between the demographic factors and fatigue, especially, sex(t==3.69 p<0.01), major(t=-2.89 p<0.01). the experience of family illness(t=2.76 p<0.01). 2. The average health promoting life style item score of the subjects was $2.33{\pm}0.33$. In the subcategories, the highest degree of performance was self-actualization(2.94), following interpersonal support(2.81). stress management(2.33), exercise(2.20), nutrition(2.10), and the lowest degree was health responsibility(1.73). There were the significant differences on the learning of health education(t=2.00 p<0.01). religion(F=3.01, p<0.05), circle activity(t=2.07, p<0.05), nutrition control(t=5.25, p<0.01) of demographical factors with the health promoting life style. 3. The correlation between the fatigue and health promoting life style made statistically no significance(r=-0.09731, p>0.05). But there was negative significant relationship between health promoting life style and psychological symptom as a fatigue subcategory(r=-0.15721, p<0.05). The self-actualization showed negative significant correlation with all fatigue subcategory. The health responsibility showed significant relationship with total fatigue(r=0.13050. p<0.05). For further research, it suggests to replicate the correlational and causal study between the fatigue and the health promoting life style using the another fatigue scale which is able to measure the subjective and objective fatigue degree. And it needs to develop the nursing intervention program for maintaining and promoting the health behavior as well as for decreasing the college students's fatigue.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.18 no.6
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• pp.571-580
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• 1985

Based on the data collected by R/V "Shinkai Maru" of the Japan Marine Fishery Resources Research Center during the period from April 1978 to April 1979, seasonal migration of Merluccius hubbsi was studied using the catch per fishing effort (tons/30 min. haul) and gonad maturity index (gonad weight /body weight X $10^3$). Merlurccius hubbsi are found in the area between $36^{\circ}S\;and\;54^{\circ}S$ along the coast of Arzentine and are abundant especially above the 100 fathoms in northern offshore of $48^{\circ}S$. It was observed that critical maturity body lengths (spawning minimum body length) in terms of gonad maturity index are 40 cm and 30cm in female and male respectively, while spawning seasons are from December to January and from November to December for female and male respectively. It was assumed that while the group which distrbutes in the north ($36^{\circ}S{\sim}39^{\circ}S$) in spring moves down south to $42^{\circ}{\sim}46^{\circ}S$ for spawning in summer (from December to January), the group which does not move or a part of this group which comes back to the north spawn in the area north of $42^{\circ}S$ throughout the long period except winter time (from July to August). Southern group as well might move north and spawn after mixing together with northern group at $42^{\circ}{\sim}46^{\circ}S$ area around the period of December to January,

• Toxicological Research
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• v.22 no.4
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• pp.381-390
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• 2006

Astaxanthine is a pigment that belongs to the family of the xanthophylls, the oxygenated derivatives of carotenoids whose synthesis in plants derives from lycopene. Astaxanthine is also a carotenoid widely used in salmonid and crustacean aquaculture to provide the pink color characteristic of that. Recent study reported that astaxanthine has the role as a detoxicant against the free radicals. On our study, we estimated the genotoxicity in ICR mice and possibility as antioxidant reagents of mutant Phaffia rhodozyma strain over expressing the astaxanthine by gamma-lay and carophyll pink including astaxanthine in apoE knock out mice, respectively. In our study, we administered Phaffia rhodozyma (2 mg and 3 mg) and carophyll pink for 4 and 8 week. The clinical sign and mortality were not detected compared with control groups. In the mutant frequency of hprt gene and chromosome aberration in splenic cells, there was not detected abnormality. There was not critical change in hematological and serum biochemical test compared to control. In expression level of repair enzyme, increase of catalase were detected and increase of expression level of Nrf-2 was detected in Phaffia rhodozyma (3 mg) and carophyll pink in 8 week treated group. In GSH level, the group of treated with Phaffia rhodozyma (3 mg) showed the increase of the GSH. In conclusion, mutant Phaffia rhodozyma and caphyll pink may be applied to the effective food additives to reduce the free radical.

• Agribusiness and Information Management
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• v.3 no.2
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• pp.43-62
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• 2011

The goal of this study is to determine, based on survey results, the underlying factors that affect the intention of the farmers who have not adopted the Hazard Analysis and Critical Control Points (HACCP) system for the rearing phase of pig production to adopt this system in the future. The research model for this study was con structed based on strategic contingency theory, the theory of the diffusion of innovation, and the technology acceptance model (TAM). Using structural equation modeling with partial least squares (PLS), this study analyzes the effects of the intensity of competition, the environmental uncertainty, the innovativeness and self-efficacy of the individual farmers, and the impact of the credibility of the Agricultural Technology Service Center (ATSC), which acts as the principal agent of technology dissemination and as a leader of change, on the perceived usefulness of technology and the farmers' intention to adopt the system. The results of the analysis are as follows. First, with regard to the underlying factors affecting the intention to adopt the new system, the intensity of competition within the industry and the institutional credibility of the ATSC were inferred to underlie the perceived usefulness. Second, institutional credibility has a positive impact on the perceived usefulness of the system, and the perceived usefulness, in turn, has a positive impact on the intention to adopt. The perceived ease of use also has a positive impact on the intention to adopt. Because the factor that has the biggest impact on the intention of a farm to adopt is the credibility of the ATSC, it is crucial for extension organizations, such as the ATSC, to make greater efforts to promote the expansion of the HACCP system. Because farmers feel that the implementation of the HACCP system is an instrumental strategy for coping with the high intensity of competition within the industry, they attempt to gain a competitive edge through the production of safe livestock products.

• Applied Biological Chemistry
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• v.40 no.3
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• pp.189-195
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• 1997

The structural basis of Iysine specificity of Achromobacter protease I (API) was investigated by means of site-directed mutagenesis. The precursor protein in which Glu190, one of the two candidates for determining Iysine specificity, was substituted by glutamine, aspartic acid or leucine was processed autocatalytically to attaln full pretense activity with lysine specificity. The substitution of the other candidate, Asp225, for asparagine or leucine produced no mature active forms of pro-API. The precursor protein of the mutant D225E slowly matured autocatalytically. The lysylendopeptidase activity of the mature D225E was 0.25% of that of native API, and this reduced activity is mainly due to a decrease in the affinity of the enzyme for lysine. These results suggest that Asp225 plays a critical rol in restricted substrate specificity as a lysylendopeptidase. However, D225E exhibited no measurable activity for synthetic ornithine substrate. Since the hydroxyl group of Ser194 in this mutant retained essentially the same reactivity to DFP or PMSF as that in native API, it can be noted that a methylene unit longer side chain of residue 225 is not compensated by a methylene unit shorter side chain at subsite P1 in the bound substrate.

• Journal of Applied Biological Chemistry
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• v.58 no.3
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• pp.219-226
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• 2015

The anticancer activity of a methanolic extract from lemon leaves (MLL) was assessed in MCF-7-SC human breast cancer stem cells. MLL induced apoptosis in MCF-7-SC, as evidenced by increased apoptotic body formation, sub-G1 cell population, annexin V-positive cells, Bax/Bcl-2 ratio, as well as proteolytic activation of caspase-9 and caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein. Concomitantly, MLL induced the formation of acidic vesicular organelles, increased LC3-II accumulation, and reduced the activation of Akt, mTOR, and p70S6K, suggesting that MLL initiates an autophagic progression in MCF-7-SC via the Akt/mTOR pathway. Epithelial-mesenchymal transition (EMT), a critical step in the acquisition of the metastatic state, is an attractive target for therapeutic interventions directed against tumor metastasis. At low concentrations, MLL induced anti-metastatic effects on MCF-7-SC by inhibiting the EMT process. Exposure to MLL also led to an increase in the epithelial marker E-cadherin, but decreased protein levels of the mesenchymal markers Snail and Slug. Collectively, this study provides evidence that lemon leaves possess cytotoxicity and anti-metastatic properties. Therefore, MLL may prove to be beneficial as a medicinal plant for alternative novel anticancer drugs and nutraceutical products.

• Journal of Korean Society for Geospatial Information Science
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• v.19 no.3
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• pp.57-66
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• 2011

The purpose of this study is to research into a method of selecting the subject parcel with a change in the category of land given surveying the land alteration state focusing on the present state of road in the government-owned and public land by using the fuzzy membership function and GIS spatial analysis. It selected the old town center of Incheon Jung-gu, and the new downtown & the forest land of Gyeyang-gu as the research subject region, and carried out GIS spatial analysis on a serial cadastral map, urban planning road layer of Korea Land Information System, practical width of road layer of Road Name Address Management System & cadastral data base, and then calculated the suitable index for the subject parcel with a change in the category of land by using the fuzzy membership function with having the critical value as the area ratio of each parcel on a serial cadastral map that was incorporated into road layer or practical width of road layer. It finally selected the parcel, which is different in land category from the real land usage, as the final subject parcel for altering land category, by using the screen of visualizing the suitable index and the aerial ortho photograph. As a result of the final selection, the fuzzy GIS spatial analysis method, which was suggested in this study, is judged to be efficient in the selection period and the methodology compared to the existing manual method. It could be confirmed to be more suitable method for downtown than forest land and for the new downtown than the old town center.

• Science of Emotion and Sensibility
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• v.12 no.1
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• pp.55-64
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• 2009

Previous research has mainly investigated the characteristics of expertise by using typical and routine tasks. This research to overcome these limitations included non-routine task situations and observed expert and novice pilots' situation awareness (SA) performance in routine and non-routine situations. Additionally, whether the ability to aware or perceive the environmental information in limited time varies with the level of expertise was tested. To this end, $2^*2^*2$ mixed factorial design was employed, including expertise (novice/expert) as a between-subjects variable and normality of fight situation (routine/non-routine) and stimulus display time (long/short) as within-subjects variables. As results, there was no performance difference in routine situations between experts and novices, while experts significantly outperformed novices in non-routine situations. When the display time became shorter, overall SA accuracy was decreased for both experts and novices, whereas experts' performance remained significantly higher than novices in short and long conditions. When we examined the interaction between the normality of fight situation and stimulus display time, there was no difference between experts and novices in routine situations for both short and long conditions. In non-routine situations, however, experts' SA accuracy was significantly higher than novices both in short and long conditions. Overall, non-routineness of flight situation does not have any impact on SA performance of experts, while it has a critical impact on SA performance of novices.

• The Journal of Industrial Distribution & Business
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• v.9 no.11
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• pp.93-104
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• 2018

Purpose - For small and medium sized firms, CEO characteristics are main factor influencing firms' prosperity as well as performance. So it is quite natural that many people are interested in factors of CEO that matters. In this research, CEO characteristics in terms of capabilities and skill or special knowledge necessary to run the business are invested for manufacturing firms. Precedent studies reveal that CEO characteristics such as psychological factors including desire to succeed, tendency to take risks, personal factors including age, year of running business, and task related factors including managing capability, communication skills, network influence firm performance for manufacturing firms. However, these studies simply verify whether or not those factors affect firm's managing performance. This study, however, goes further to investigate how is the affecting process from CEO's capabilities and organization characteristics to firm's core competence, and from core competence to advantages, and from advantages to managing performance. Research design, data, and methodology - We make a questionnaire and surveyed manufacturing firm CEO's in Gyeonggi-do area. General characteristics analysis, factor analysis, regression analysis, and control effect analysis was conducted. SPSS 2.0 Win, version was used. Results - The CEO characteristics including basic capability, task capability, leadership, and organization characteristics affect core competence at the statistically significant level. And, core competence affect both price advantage and differentiation advantage at the significant level. Some unique finding is that while differentiation advantage affects both financial achievement and non-financial achievement, price advantage does not affect both financial and non-financial achievement. And firm characteristics mainly measured by CEO characteristics of skills has control effects on the trace from core competence to price advantage. Conclusions - For small and medium sized firms CEO characteristics is the most important factor influencing firm's prosperity. For manufacturing firms, whether CEO has the skill or special knowledge to run the firm is critical factor. The study results show that CEO's for manufacturing firms put importance on price and price advantage which seems to be familiar to them. However, the price advantage does not influential to financial and non-financial achievement. This result suggests that small and medium sized manufacturing firms' CEO's should make effort to improve other aspects of advantages to be more competitive.

• Geophysics and Geophysical Exploration
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• v.23 no.2
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• pp.97-114
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• 2020

Recently, many studies have been actively conducted on the application of machine learning in all branches of science and engineering. Studies applying machine learning are also rapidly increasing in all sectors of seismic exploration, including interpretation, processing, and acquisition. Among them, fault detection is a critical technology in seismic interpretation and also the most suitable area for applying machine learning. In this study, we introduced various machine learning techniques, described techniques suitable for fault detection, and discussed the reasons for their suitability. We collected papers published in renowned international journals and abstracts presented at international conferences, summarized the current status of the research by year and field, and intensively analyzed studies on fault detection using machine learning. Based on the type of input data and machine learning model, fault detection techniques were divided into seismic attribute-, image-, and raw data-based technologies; their pros and cons were also discussed.