• 디자인학연구
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• 제16권3호
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• pp.241-252
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• 2003

2003년 현재 광고매체로서 인터넷의 위상이 확고해지고, 기업의 인터넷광고 활용이 높아지면서 소비자들은 다양한 인터넷광고를 접할 수 있게 되었다. 그리하여 비약적으로 발전한 인터넷 환경과 더불어 새로운 기술로 제작된 여러 가지 형태의 헤아릴 수도 없을 만큼 많은 인터넷 광고가 집행되고 또 사라져 가고 있다. 이제 지난 10년간의 급격한 환경변화에 따라 다양하게 제작ㆍ실험되고 있는 인터넷 광고의 여러 가지 유형 및 표현기법들을 체계적으로 분류하고 동시에 국내 인터넷 광고의 발전 방향 및 추세를 파악할 필요성이 있다. 인터넷 광고 디자인은 4대 매체 광고에서처림 거시적인 차원에서 광고 전략 및 표현전략에 의해 제작되어야 하는 시점이기 때문이다. 따라서 본 논문은 먼저 현재까지 제작된 국내 인터넷 광 고의 유형을 마케팅, 광고목적별, 표출형태별, 제작기술별, 표현방식별로 5가지 측면에서 체계적으로 분류하여 그 형태와 특징을 살펴보았다. 다음으로 인터넷 마케팅 패러다임의 변화 를 살펴보는 한편, 소비자 이용성향의 변화와 인터넷 광고 제작기술의 변화에 따른 최근 국내 인터넷 광고의 추세를 살펴보고 마케팅 측면과 제작기술 측면, 크리에이티브 측면에서 그 발전방향을 고찰해 보았다. 마지막으로 이를 바탕으로 인터넷 광고의 효과를 높이기 위해 크리에이티브 측면을 고려한 인터랙션 광고기법의 개발 및 상호작용성을 증진시키는 표현 전략 수립의 필요성을 제안하고자 한다.

• 한국의류학회지
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• 제36권2호
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• pp.194-205
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• 2012

Historically, garments have been spontaneously made with human instinct in order to warm and decorate the body using textiles that have been made and used by various peoples in different cultures. Contemporary garments have been used as a means of warming as well as express individual personality and a desire to pursue beauty. They have a unique formativeness and a symbolic nature according to cultural phenomena that reflect a cultural outcome that expresses contemporary thinking and ideology as well as their aesthetic consciousness. This study globally promotes Chinese opera mask culture and proposes the possibility of creative thinking through the introduction of Chinese opera mask elements into contemporary fashion, expressing them as patchworks. In order to endow artistic value (required in contemporary fashion) this study creates works by analyzing and applying a formative sense seen in patchwork techniques and the characteristics of Chinese opera masks; in addition, it sought the possibility of new expressions in garment designs. The results obtained from the research involve the following. First, the introduction of the traditional patchwork technique to contemporary garments may be a dynamic theme of garment expression and exceed stereotypical ideas that enable the creation of designs attuned to the globalization era. Second, it was possible to pursue independent formativeness which is in harmony with a modern sense through the restructuring of the harmony of colors and practical characteristics found in patchworks. Third, it was possible to demonstrate their artistry and unique effect in the expression of contemporary garments by the expression of the analyzed results of characteristic patterns of Chinese opera masks with a patchwork technique in creating works. Results show that it is necessary to conduct research into a patchwork technique that applies diverse materials as a new method to develop contemporary garment design also as a creative design. In addition, if the analyzed results of the characteristic patterns of Chinese opera masks can be expressed with a patchwork technique, they may be able to exhibit a genuine effect along with the artistry of expression in contemporary garments; thereby, relevant follow-up research should be further continued.

• 한국교육논총
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• 제43권1호
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• pp.59-87
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• 2022

본 연구는 <사고와 표현2> 수업에서 문학 작품 읽기 연계 다시 쓰기 수업 사례를 소개하는 것을 목적으로 한다. 본 수업에서는 미셸 투르니에의 단편 「기쁨이 내게 머물게 하소서」를 읽고 조별활동에서 작품을 읽은 소감과 느낌을 나누고 각자 작품에 대한 질문을 하나씩 제시하여 조원들과 함께 나누었다. 이어 수업에서 치유의 방향으로 작품 마지막 장면 다음에 올 내용을 창작하는 작품 결말 이어쓰기 리텔링과 성찰의 방향을 독자 자신의 삶의 영역으로 돌려 자기가 바라는 미래 자아상을 상상해보고 그것이 이미 실현된 것으로 가정하는 미래 일상 미리쓰기 리텔링을 하였다. 본 수업에서 시행한 작품 읽기 연계 리텔링은 읽기-생각하기-표현하기를 아우르는 유기적 학습방법으로서의 의의가 있다. 또한 작품에 담긴 인간과 삶에 대한 성찰을 음미하고 작품에 담긴 문제들에 대한 해결방안을 담은 재창작을 통해 리텔링은 치유와 회복의 가치를 만든다. 본 수업에서 시행한 미래 일상 미리 쓰기는 리텔링의 방향을 독자 자신에게로 돌리게 하여 학생들로 하여금 자기가 바라는 미래 자아상을 생생하게 설계하고 자신의 비전을 향해 나아가는 데 도움을 줄 수 있는 실천인문학으로서의 의미가 있다.

• Journal of Microbiology and Biotechnology
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• 제27권12호
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• pp.2129-2140
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• 2017

Silibinin is the major active component of silymarin, extracted from the medicinal plant Silybum marianum. Silibinin has potent antibacterial activity; however, the exact mechanism underlying its activity has not been elucidated. Here, we investigated the novel mechanism of silibinin against Escherichia coli. Time-kill kinetic assay showed that silibinin possess a bactericidal effect at minimal inhibitory concentration (MIC) and higher concentrations (2-and 4-fold MIC). At the membrane, depolarization and increased intracellular $Ca^{2+}$ levels were observed, considered as characteristics of bacterial apoptosis. Additionally, cells treated with MIC and higher concentrations showed apoptotic features like DNA fragmentation, phosphatidylserine exposure, and caspase-like protein expression. Generally, apoptotic death is closely related with ROS generation; however, silibinin did not induce ROS generation but acted as a scavenger of intracellular ROS. These results indicate that silibinin dose-dependently induces bacterial apoptosis-like death, which was affected by ROS depletion, suggesting that silibinin is a potential candidate for controlling bacteria.

• 한국의상디자인학회지
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• 제4권1호
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• pp.173-183
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• 2002

The orchid has a very elegant color and various forms in the nature or the ground for human life and the mother of life, The purpose of this study is to express some creative formative art by using the orchid as motive, and thereby, suggest the possibility of an artistic modern costume design by reviewing the texture of the materials. The results of this study can be summarized as follows; First, it was confirmed through this study that the orchid with diverse forms and colors can be used as design motive in almost infinitely diverse ways, and that all the artificial forms or structures contain the elements of natural beauty. Second, the luxurious and rich sense of orchid‘s color can be maximized by using the complementary contrast effect of the dyeing technique and the color gradation effect through harmony among similar colors. Third, a high value-added costume can be created to meet modern men’s aesthetic desire by using such embroidery techniques as crochet, weaving, dyeing, beads embroidery and art flower. Fourth, different effects of texture can be rendered by using different materials of various textures and characteristics. In addition, the possibility of creative expression for costume as formative art can be enhanced by expanding the expressions of the materials.

• 한국콘텐츠학회논문지
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• 제13권12호
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• pp.672-679
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• 2013

창의성은 문제인식과 해결방법으로 상상력을 통한 새로운 이미지의 사고능력과 표현이다. 이 연구는 신체움직임의 창의성이론을 탐구하고 창의성 요인을 분석하였다. 연구결과, 신체움직임의 창의성은 첫째, 움직임 자각 둘째, 신체움직임 디자인 셋째, 움직임의 발견, 넷째, 움직임활용이라는 단계가 필요하다. 자기지각과 자아개념을 통한 새로운 이미지의 활용은 문제인식과 해결기능에 대한 창의적인 향상을 가져온다. 결론적으로 신체움직임의 창의성은 상호작용에 의한 '제3의 힘'과 '흐름의 유연성'으로 신체움직임의 무한성을 의미한다.

• BMB Reports
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• 제51권5호
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• pp.209-210
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• 2018

NAFLD induces the development of advanced liver diseases such as NASH and liver cancer. Therefore, understanding the mechanism of NAFLD development is critical for its prevention and treatment. Ablation of PTEN or Hippo pathway components induces liver cancer in a murine model by hyperactive AKT or YAP/TAZ, respectively. Although the regulation of these two pathways occurs in the same hepatocyte, the details of crosstalk between Hippo-YAP/TAZ and PTEN-AKT pathways in liver homeostasis and tumorigenesis still remain unclear. Here, we found that depletion of both PTEN and SAV1 in liver promotes spontaneous NAFLD and liver cancer through hyperactive AKT via YAP/TAZ-mediated up-regulation of IRS2 transcription. Conversely, NAFLD is rescued by both ablation of YAP/TAZ and activation of the Hippo pathway. Furthermore, human HCC patients with NAFLD showed strong correlation between YAP/TAZ and IRS2 or phospho-AKT expression. Finally, the inhibition of AKT by MK-2206 treatment attenuates NAFLD development and tumorigenesis. Our findings indicate that Hippo pathway interacts with AKT signaling during the intervention with IRS2 to prevent NAFLD and liver cancer.

• 국제초고층학회논문집
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• 제5권4호
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• pp.271-291
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• 2016

There is much architectural and engineering literature which discusses the virtues of exterior bracing and diagrid systems in regards to sustainability - two systems which generally reduce building materials, enhance structural performance, and decrease overall construction cost. By surveying past, present as well as possible future towers, this paper examines another attribute of these structural systems - the blend of structural functionality and aesthetics. Given the external nature of these structural systems, diagrids and exterior bracings can visually communicate the inherent structural logic of a building while also serving as a medium for artistic effect. Viewed in this light, the visual appeal of these systems can be enhanced to give a tower a more distinct urban identity. This entails the creation of structural elements that are aesthetically pleasing, geometrically coherent and that demonstrate dexterity of application in regards to a building's composition, while also respecting the laws of physics and mechanics. In this fashion, an artistic approach can exhibit structural systems as not just purely rational features that enable the construction of tall buildings, but as important visual components that afford opportunities for creative expression. This paper, therefore, synthesizes the concepts of structural performance and creative artistry to facilitate a better understanding of the aesthetic developments in skyscrapers worldwide.

• BMB Reports
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• 제53권7호
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• pp.385-390
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• 2020

Inflammatory Bowel Disease is caused by an acute or chronic dysfunction of the mucosal inflammatory system in the intestinal tract. In line with the results of our previous study, wherein we found that the PKCα-LSD1-NF-κB signaling plays a critical role in the prolonged activation of the inflammatory response, we aimed to investigate the effect of signaling on colitis in the present study. Lsd1 S112A knock-in (Lsd1^SA/SA) mice, harboring a deficiency in phosphorylation by PKCα, exhibited less severe colitis symptoms and a relatively intact colonic epithelial lining in dextran sulfate sodium (DSS)-induced colitis models. Additionally, a reduction in pro-inflammatory gene expression and immune cell recruitment into damaged colon tissues in Lsd1^SA/SA mice was observed upon DSS administration. Furthermore, LSD1 inhibition alleviated colitis symptoms and reduced colonic inflammatory responses. Both LSD1 phosphorylation and its activity jointly play a role in the progression of DSS-induced colitis. Therefore, the inhibition of LSD1 activity could potentially protect against the colonic inflammatory response.

• 복식
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• 제59권4호
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• pp.41-53
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• 2009

This study analyzed expression types of dot patterns and derived out inherent characteristics to provide fundamental resources for advancement of high value added creative designs. As a result of the study, Firstly, the circular motive was used to form silhouettes or as a symbol of a decoration. Secondly, a simple form and color dot pattern was used to create one side, or a circular shaped accessory was used to be recognized as a construction line or a decoration line. Thirdly, textile printing is mainly used but handicraft and decorative images were used to add vitality through piece technique, embroidery, collage, cut-out, patch work, etc. Fourthly, different circular motives were integrated, partitioned and duplicated for abstract geometrical images. Fifthly, variations were added by mixing different dot patterns that are arranged regularly and irregularly in different sizes and gaps creating compounded designs with handicraft touches, different angles or on top of each other. Sixthly, hybrid images were created with rearrangement of dot patterns and by adding floral shapes, stripes or other abstract and geometrical shapes. Such various and creative attempts construct new formative beauty in fashion design and I believe that it can establish the development of unique images that satisfies the taste of today's consumers.