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Electrochemical Properties of Organic Ultra Thin Films of Fatty Acid and Phospholipid Mixture (지방산과 인지질 혼합 유가초박막의 전기화학적 특성)

  • Park, Keun-Ho;Choi, Sung-Hyun;Son, Tae-Churl;Song, Ju-Yeong
    • Journal of the Korean Applied Science and Technology
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    • v.23 no.2
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    • pp.137-146
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    • 2006
  • We investigated the electrochemical properties for Langmuir-Blodgett (LB) films mixed with fatty acid (8A5H) and phospholipid (DLPE, DMPC, and DPPA). LB films of 8A5H monolayer and 8A5H-phospholipid mixture were deposited using the Langmuir-Blodgett method on the indium tin oxide(ITO) glass. The electrochemical properties measured using cyclic voltammetry with three-electrode system, an Ag/AgCl reference electrode, a platinum wire counter electrode and LB film-coated ITO working electrode at various concentrations(0.1, 0.5, and 1.0 mol/L) of $NaClO_4$ solution. A measuring range was reduced from initial potential to -1350 mV, continuously oxidized to 1650 mV and measured to the initial point. The scan rate was 50, 100, 150 and 200 mV/s, respectively. As a result, LB films of fatty acid and phospholipid (8A5H/DLPE and DPPA) appeared irreversible process were caused by only the reduction current from the cyclic voltammogram and LB film of 8A5H-DMPC mixture was found to be caused by a reversible oxidation-reduction process.

A Study on the Electrochemical Characteristics of Langmuir-Blodgett Nano-Films of Phospholipid Compound (인지질 화합물의 나노 Langmuir-Blodgett막의 전기화학적 특성에 관한 연구)

  • Jung, A-Jin;Park, Keun-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.29 no.2
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    • pp.311-316
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    • 2012
  • We are investigated to an electrochemical characteristic for Langmuir-Blodgett (LB) films by cyclic voltammetry method. The phospholipid compound was deposited by using the LB method on the Indium tin oxide(ITO) glass. We tried to measure the electrochemical by using cyclic voltammetry with three-electrode system(an Ag/AgCl reference electrode, a platinum wire counter electrode and LB film-coated ITO working electrode) in 0.5, 1.0, 1.5 and 2.0 N $NaClO_4$ solution. A measuring range was reduced from initial potential -1350 mV, continuously oxidized to 1650 mV. As a result, LB films of the phospholipid compounds are appeared irreversible process caused by only the oxidation current from the cyclic voltammogram. The diffusivity(D) effect of LB films decreased with increasing of phospholipid compound amount.

Application and therapeutic effects of sickle red blood cells for targeted cancer therapy (표적항암치료를 위한 겸형적혈구의 응용 및 치료 효과)

  • Choe, Se-woon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.12
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    • pp.2395-2400
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    • 2016
  • Conventional drug carriers such as liposomes, nanoparticles, polymer micelles, polymeric conjugate and lipid microemulsion for cancer chemotherapy shield normal tissues from toxic drugs to treat cancer cells in tumors. However, inaccurate tumor targeting uncontrolled drug release from the carriers and unwanted accumulation in healthy sites can limit treatment efficacy with current conventional drug carriers with insufficient concentrations of drugs in the tumors and unexpected side effects as a result. Sickle red blood cells show natural tumor preferential accumulation without any manipulation due to the adhesive interaction between molecular receptors on the membrane surface and counter-receptor on endothelial cells. In addition, structural changes of microvascular in tumor sites enhances polymerization of sickle red blood cells. In this research, we examined the use of sickle red blood cells as a new drug carrier with novel tumor targeting and controlled release properties to quantify its therapeutic effects.

Improving Efficiencies of DSC by Down-conversion of LiGdF4:Eu (Eu이 도핑된 LiGdF4의 Down-conversion을 이용한 염료감응형 태양전지의 효율 향상)

  • 김현주;송재성;김상수
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.17 no.3
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    • pp.323-328
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    • 2004
  • Down-conversion of Eu$^{3+}$ doped LiGdF$_4$ (LGF) for increasing the cell efficiency on dye-sensitized Ti $O_2$ solar cells has been studied. The dye sensitized solar cell (DSC) consisting of mesoporous Ti $O_2$ electrode deposited on transparent substrate, an electrolyte containing I$^{[-10]}$ /I$_3$$^{[-10]}$ redox couple, and Pt counter electrode is a promising alternative to the inorganic solar cell. The structure of DSC is basically a sandwich type, viz., FTO glass/Ru-red dye-absorbed Ti $O_2$/iodine electrolyte/sputtered Pt/FTO glass. The cell without down converter had open circuit potential of approximately 0.66 Volt, the short circuit photocurrent density of 1.632 mA/$\textrm{cm}^2$, and fill factor of about 50 % at the excitation wavelength of 550 nm. In addition, 5.6 mW/$\textrm{cm}^2$ incident light intensity beam was used as a light source. From this result, the calculated monochromatic efficiency at the wavelength of 550 nm of this cell was about 9.62 %. The incident photon to current conversion efficiency (IPCE) of N3 used as a dye in this work is about 80 % at around 590 nm and 610 nm, which is the emission spectrum of Eu$^{3+}$ doped LGF, results in efficiency increasing of DSC.C.

Evaluation of Capture Efficiencies of Push-Pull Hood Systems by Trace Gas Method under the Presence of Some Cross-draft (방해기류 존재시 추적자 가스법을 이용한 푸쉬풀 후드 효율 평가)

  • Kim, Tae-Hyeung;Ha, Hyun-Chul;Kang, Ho-Gyung
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.3
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    • pp.290-301
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    • 2006
  • A push pull hood system is frequently applied to control contaminants evaporated from an open surface tank. Efficiency of push pull hood system is affected by various parameters, such as, cross draft, vessel shapes, tank surface area, liquid temperature. A previous work assisted by flow visualization technique qualitatively showed that a strong cross draft blown from the pull hood to push slot could destroy a stable wall-jet on the surface of tank, resulting in the abrupt escape of smoke from the surface. In this study, the tracer gas method was applied to determine the effect of cross-draft on the capture efficiency qualitatively. A new concept of capture efficiency was introduced, that is, linear efficiency. This can be determined by measuring the mass of tracer gas in the duct of pull hood while the linear tracer source is in between push slot and pull hood. By traversing the linear tracer source from the push slot to the pull hood, it can be found where the contaminant is escaped from the tank. Total capture efficiency can be determined by averaging the linear efficiencies. Under the condition of cross-draft velocities of 0, 0.4, 0.75, 1.05 and 1.47m/s, total capture efficiencies were measured as 97.6, 95.4, 94.6, 92.7 and 70.5% respectively. The abrupt reduction of efficiency with cross-draft velocity of 1.47m/s was due to the destruction of tank surface wall-jet by the counter-current cross-draft. The same phenomenon was observed in the previous flow visualization study. As an alternative to overcome this abrupt efficiency drop, the 20% increase of hood flow rates was tested, resulting in 20% efficiency increase.

Strategy for Insecticide Resistance Management Approach to IPM

  • Motoyama, Naoki;Dauterman, W.C.
    • Korean journal of applied entomology
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    • v.31 no.3
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    • pp.314-327
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    • 1992
  • Insecticide resistance is a serious is a serious threat to IPM, resulting in various adverse effects not to mention the loss of yield in agriculture. One approach to counter the problem is the disruption of resistance mechanisms. This can be achieved by (1) compounds which show a negative correlation with resistance at the site of action, (2) specific metabolic inhibitors which serve as synergists, or (3) a certain combination of two insecticides producing a joint action. This approach, however, requires certain precautions for the side effects may cause an increase in toxicity to mammals. Owing to the recent advances in theoretical studies on resistance management employing computer simulation and mathematical models, a few principles to reduce the risk of development of resistance have been clarified. They are helpful in designing operational strategies with regard to, for instance, insecticide doses to be applied, mode of application, and choice and nature of the insecticide(s) to be used. For restoration of insecticide susceptibility of a resistant population, reintroduction of susceptible individuals to the resistant population is feasible when certain conditions are met. Natural enemies which developed resistance to insecticides can be an important component of IPM as has been shown in the pest management in apple orchards. After all, the implementation of a successful resistance management program depends upon cooperation between different sigments of the agricutural community. Although resistance is a preadaptive phenomenon, in some cases spontaneous loss of resistance does occur without contamination by susceptible individuals. The instability of resistance in these insects implies the possible existence of a switch machanism controlling the expression of resistance gene(s). Elucidation of such a mechanism may eventually provide us with a new technical approach with which we can combat the problem of insecticide resistance.

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Continuous dialysis of selected salts of sulphuric acid

  • Bendova, Helena;Snejdrla, Pavel;Palaty, Zdenek
    • Membrane and Water Treatment
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    • v.1 no.3
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    • pp.171-179
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    • 2010
  • The transport of selected salts of sulphuric acid (cobalt, copper, iron(II), manganese, nickel and zinc sulphate) through an anion-exchange membrane Neosepta-AFN was investigated in a counter-current continuous dialyzer at various salt concentrations and volumetric liquid flow rates. The basic transport characteristics - the rejection coefficient of salt and the permeability of the membrane - were calculated from measurements at steady state. The salt concentration in model mixtures was changed in the limits from 0.1 to 1.0 kmol $m^{-3}$ and the volumetric liquid flow rate of the inlet streams was in the limits from $8{\times}10^{-9}$ to $24{\times}10^{-9}m^3\;s^{-1}$. Under the experimental conditions given, the rejection coefficient of salts tested was in the range from 65% to 94%. The lowest values were obtained for iron(II) sulphate, while the highest for copper sulphate. The maximum rejection of salt was reached at the highest volumetric liquid flow rate and the highest salt concentration in the feed. The permeability ($P_A$) of the Neosepta-AFN membrane for the individual salts was in the range from $0.49{\times}10^{-7}m\;s^{-1}$ to $1.8{\times}10^{-7}m\;s^{-1}$ and it can be described by the following series: $P_{FeSO_4}$ < $P_{NiSO_4}$ < $P_{ZnSO_4}$ < $P_{CoSO_4}$ < $P_{MnSO_4}$ < $P_{CuSO_4}$. The permeability of the membrane was strongly affected by the salt concentration in the feed - it decreased with an increasing salt concentration.

Sensitivity Analyses for Maximum Heat Removal from Debris in the Lower Head

  • Kim, Yong-Hoon;Kune Y. Suh
    • Nuclear Engineering and Technology
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    • v.32 no.4
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    • pp.395-409
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    • 2000
  • Parametric studies were performed to assess the sensitivity in determining the maximum in-vessel heat removal capability from the core material relocated into the lower plenum of the reactor pressure vessel (RPV)during a core melt accident. A fraction of the sensible heat can be removed during the molten jet delivery from the core to the lower plenum, while the remaining sensible heat and the decay heat can be transported by rather complex mechanisms of the counter-current flow limitation (CCFL) and the critical heat flux (CHF)through the irregular, hemispherical gap that may be formed between the freezing oxidic debris and the overheated metallic RPV wall. It is shown that under the pressurized condition of 10MPa with the sensible heat loss being 50% for the reactors considered in this study, i.e. TMI-2, KORI-2 like, YGN-3&4 like and KNGR like reactors, the heat removal through the gap cooling mechanism was capable of ensuring the RPV integrity as much as 30% to 40% of the total core mass was relocated to the lower plenum. The sensitivity analysis indicated that the cooling rate of debris coupled with the sensible heat loss was a significant factor The newly proposed heat removal capability map (HRCM) clearly displays the critical factors in estimating the maximum heat removal from the debris in the lower plenum. This map can be used as a first-principle engineering tool to assess the RPV thermal integrity during a core melt accident. The predictive model also provided ith a reasonable explanation for the non-failure of the test vessel in the LAVA experiments performed at the Korea Atomic Energy Research Institute (KAERI), which apparently indicated a cooling effect of water ingression through the debris-to-vessel gap and the intra-debris pores and crevices.

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A Study on the User-driven Urban Park Development Plan Awareness Survey - Focusing on Lawns·Grass Area - (의식조사를 통한 이용자 중심의 도시공원 조성방안 연구 - 잔디·녹지공간을 중심으로 -)

  • Seo, Jung-Young;Sung, Hyun-Chan
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.12 no.2
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    • pp.61-72
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    • 2009
  • This study aims to analyze the current situation of and issues in the structure of urban neighborhood parks and park facility installation in cities in Gyeonggi-do. Then, based on its findings, plans to improve the space structure of the parks were examined and suggested to raise the city environment improvement function and green area base function of urban parks and fully satisfy users' needs for pleasant rest, recreation and cultural activities. The findings showed that, within parks, the area of grass where access was restricted reached about 24.4% in average. In other words, only 75.6% of total park area could be freely used by park visitors. As for an improvement plan, the grass area where access is limited may be converted into a gras area that can be freely used to raise the park use area, which currently stands only at 75.6%, to 100%. The result of cross analysis through Chi-Square Test regarding lawn use as well as regarding (dis)agreement with reduction of lawn, based on the investigation of cognition, showed a significant agreement of park users with reduction of green areas. Therefore it is considered that lawn space must be reduced according the result of the analysis, to set up plans for facility space that would meet the desires of users. The analysis of user behaviors revealed that many of them used square spaces and walks; therefore it is considered that re-structuring of space is necessary according to local characteristics. This study also made some policy suggestion. urban parks must be a base of city green areas to counter climate changes. When developing a park creation plan, a user demand survey must be conducted in advance. In addition. grass construction methods should be improved to tolerate foot pressure.

Application of Differential GPS for the Displacement Measurement of Self-anchored Suspension Bridge under the Static and Dynamic Loading Cases (DGPS 기법을 이용한 자정식 현수교의 정동적 변위응답 측정 및 분석)

  • Kim, Hyung-Tae;Seo, Ju-Won
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.19 no.11
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    • pp.1126-1132
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    • 2009
  • Bridge structures are designed to support ordinary loadings such as vehicles, wind, temperature and current as well as unexpected loadings like earthquakes and storm. Especially, the displacement of Flexible bridges like an suspension bridge under ordinary loading conditions is necessary to be monitored. In case of long span bridges, there are some difficulties in monitoring the displacement of center of the main span using traditional laser displacement sensors. In this study, the static and dynamic displacement responses due to vehicle loadings were measured by DGPS(differential global positioning system) technique. The displacement response data were compared with data obtained from traditional laser displacement sensors so that the static and dynamic behavior of the bridge under vehicle loadings was examined and the applicability of the displacement response measurement using DGPS technique was verified. The static and dynamic loading test for an self-anchored suspension bridge, So-rok Bridge, was performed using vehicles. The displacement response from DGPS technique and that from laser displacement sensors of the bridge monitoring system were compared. The amplitude of white noise from DGPS based measurement was about 7 mm and that of laser displacement sensor based measurement was about 3 mm. On the other hand, dynamic behavior of the center of main span from DGPS based measurement showed better agreement with influence line of the bridge than that from laser displacement sensors. In addition, there were some irregular and discontinuous variation of data due to the instability of GPS receivers or frequent appearance of GPS satellites. Post-processing via the reference station close to an observation post provided by NGII(National Geographic Information Institute) will be a counter-plan for these defects.