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Peripheral Neutrophil Count and Respiratory Failure in Preterm Infant (조산아에서 말초혈액 중성구수와 호흡 부전증과의 연관성)

  • Lee, Kum Joo;Yun, Soo Young;Lee, Ran;Hean, Jae Ho;Jung, Ghee Young;Park, Jin Hee;Park, Young Sun
    • Clinical and Experimental Pediatrics
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    • v.45 no.5
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    • pp.596-602
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    • 2002
  • Purpose : The purpose of this study was to analyze the association of peripheral neutrophil count with the development of respiratory failure in preterm infants. Methods : A retrospective study was conducted from January 1993 to December 1999 on 44 preterm infants, who were admitted to the neonatal intensive care unit of St. Francisco hospital. Preterm infants(birth weight 500 to 1,350 gm) who had a complete blood count obtained within 2 hours after delivery. Patients in the lowest of neutrophil count(early neutropenia, < $1.0{\times}10^9/L$) were compared with patients in the remaining group. Results : Low neutrophil count were transient in early neutropenia group. The concentration the circulating neutrophil count rose from $0.85{\pm}0.11{\times}10^9/L$ at average of 2 hours after delivery to $5.3{\pm}2.7{\times}10^9/L$ at 24 hours after delivery in the early neutropenia group and from $3.6{\pm}1.6{\times}10^9/L$ to $5.8{\pm}3.2{\times}10^9/L$ in the non-neutropenia group during the same time period. Compare to the non-neutropenia group, the neutropenia group had a lower birth weight($1,046.50{\pm}180.76gm$ Vs $1,156.70{\pm}124.99gm$), a lower Apgar score(1 min : $3.41{\pm}1.18$ Vs $4.30{\pm}1.46$, 5 min : $5.41{\pm}0.87$ Vs $6.15{\pm}0.95$), and a higher incidence of bronchopulmonary dysplasia(27.27% Vs 7.0%). Patients who had early neutropenia were more likely to require mechanical ventilation, supplemental oxygen and hospital stay. Also, main effect factors for the two groups were birth weight(Odds ratio=5.457, 95% CI=1.551-27.525), initial peripheral blood white cells(odds ratio=8.308, 95% CI=2.054-52.699), and bronchopulmonary dysplasia(odds ratio=0.099, 95% CI=0.017-0.397). Conclusion : A low count of neutrophil in the systemic circulation of premature infants within 2 hours of birth is associated with more severe respiratory distress.

The Effects of Daecheongryoung-tang on Anti-weight Gain and Anti-hyperlipidemic in Obese Sprague Dawley Rat Induced by High Fat Diet (대청룡탕이 비만 유도 흰쥐의 체중 감량과 혈중지질농도 개선에 미치는 영향)

  • Cho, Eun Jin;Yang, Seung Jeong;Cho, Seong Hee
    • Journal of Korean Medicine for Obesity Research
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    • v.18 no.1
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    • pp.27-35
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    • 2018
  • Objectives: The aim of this study is to investigate the effects of Daecheongryoung-tang (DCR) therapy on body weight, serum total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level and complete blood cell count of obese rats. Methods: 34 rats are divided into 4 groups, the rats in the normal group are 7 and the rats in the other group are 9 per group; Normal group (general fat diet and no medication), Control group (high-fat diet and no medication), DCR_L group (high-fat diet and DCR 250 mg medication) and DCR_H group (high-fat diet and DCR 500 mg medication). DCR is administrated for 6 weeks. Results: There is significant statistical difference between Control group and DCR-H group for the body weight, the total cholesterol, LDL cholesterol, triglyceride, free fatty acid level. Also, there is significant statistical difference among Control group, DCR_L group and DCR_H group for body weight, triglyceride, free fatty acid and phospholipid level. Conclusions: These results suggest that medication of DCR_L and DCR_H is effective for the treatment of obesity.

Relationship Between Lower Extremity Extensor Strength and Wall Squat Performance

  • Jung, Sung-hoon;Hwang, Ui-jae;Kim, Jun-hee;Jeon, In-cheol;Kwon, Oh-yun
    • Physical Therapy Korea
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    • v.26 no.4
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    • pp.20-28
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    • 2019
  • Background: The wall squat exercise has been recommended for strengthening of the lower extremity muscles with maintaining lumbar lordosis. Although squat has been studied to be related to lower extremity extensor strength, the relationship between wall squat and lower extremity extensor strength unclear. Because squat and wall squat are biomechanically different, study on the relationship is needed. Objects: The purpose of this study was to determine the lower extremity extensor strength associated with wall squat performance. Methods: 74 healthy volunteers were recruited to participate in this study. The volunteers were measured hip and knee extensors strength and then performed wall squat exercise for maximum count. Results: We found significant relationships between wall squat performance and hip extensor strength normalized by body weight, knee extensor strength normalized by body weight and the composite value. In a regression analysis, hip extensor strength normalized by body weight explained 29% of the variation in wall squat performance in males and 35% in females. Conclusion: These results demonstrate that hip extensor strength normalized by body weight is critical to wall squat performance in both sexes.

Analysis on Literature Review of Internet of Things Adoption Among the Consumer at the Individual Level

  • Mahmud, Arif;Husin, Mohd Heikal;Yusoff, Mohd Najwadi
    • Journal of Information Science Theory and Practice
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    • v.10 no.2
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    • pp.45-73
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    • 2022
  • The research in the literature review on Internet of Things (IoT) adoption from an individual consumer viewpoint is minimal and has not yet been fully investigated. Therefore, the objectives of this study are to analyze the growth of IoT in recent years and to conduct a weight analysis of the factors that affect acceptance intentions and real usage of IoT-enabled services. For the review, we analyzed 87 publications from 13 conferences and 54 journals published during the period 2014-2020 about consumer adoption of IoT. Following the study, we discovered an unprecedented increase in the number of articles published in the last seven years, which points to an emerging area with an enormous prospect. Furthermore, the weight analysis outcome was associated with the diagrammatic representation in this study. After that, this research developed a generalized consumer IoT adoption model based on the 12 best predictors derived from frequency count and weight analysis, which had the highest predictive power for calculating IoT adoption. This paper further acknowledges the study's theoretical and practical contributions, as well as its shortcomings, and proposes further research directions for future researchers.

Platelet count and mean platelet volume in low birth weight infants (≤2,000 g) with sepsis (패혈증에 이환된 저출생체중아(≤2,000 g)에서 혈소판수치와 평균혈소판용적의 변화)

  • Lee, Wan-soo;Cho, Jin-young;Yoo, Seung-taek;Lee, Chang-woo;Choi, Doo-young;Kim, Jong-duck;Oh, Yeon-kyun
    • Clinical and Experimental Pediatrics
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    • v.50 no.7
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    • pp.643-648
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    • 2007
  • Purpose : Sepsis is a common complication in Neonatal Intensive Care Units (NICU), seen especially in low birth weight (LBW) infants. A recent study showed that fungal or gram-negative sepsis is associated with a greater degree of thrombocytopenia than is seen with gram-positive sepsis. So, this study was undertaken to examine the platelet counts and platelet indices in LBW infants during episodes of sepsis. Methods : We analyzed 36 cases with culture-proven sepsis on chart review in LBW infants admitted to the NICU at Wonkwang University Hospital from January 2001 to June 2006. Results : Patients were grouped by organism type: gram-positive bacteria ($1,521{\pm}309g$, $31.3{\pm}2.9wk$, 15/36), gram-negative bacteria ($1,467{\pm}290g,\;30.6{\pm}3.6wk$, 17/36), and fungi ($1,287{\pm}205g,\;30.0{\pm}3.9wk$, 4/36). The most common organism was Staphylococcus epidermis and the incidence of thrombocytopenia was 88.9%. When compared with infants with gram-positive sepsis, those with gram-negative sepsis had significantly higher incidences of thrombocytopenia, lower initial platelet count, lower platelet nadir, and greater mean percentage decrease in platelet count from before the onset of sepsis. Those with fungal infections were similar to gram-negative sepsis, but they were not significant because of the small number of patients. And mean platelet volume (MPV) in sepsis was increased more significantly in time of platelet nadir than before the onset of sepsis. Conclusion : We conclude that decrease in platelet count was significantly greater in gram-negative sepsis than gram-positive sepsis, and also greater than fungal sepsis-which was insignificant because of the small number of patients-in LBW infants. And elevation in MPV will be helpful in the diagnosis and treatment of sepsis in LBW infants.

Effects of Erythrosine on Murine Immune Functions and Methemoglobin Formation (식품 첨가물의 면역독성 및 혈액독성 - Erythrosine이 마우스의 면역기능과 Methemoglobin형성에 미치는 영향 -)

  • 황미경;윤혜정;유충규;문창규
    • Journal of Food Hygiene and Safety
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    • v.2 no.4
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    • pp.191-196
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    • 1987
  • Erythrosine used as a colouring agent in drugs, cosmetics and foods in Korea, was examined for its effects on murine immune system and methemoglobin formation. As immunotoxicologic assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathotoxicology, IgM plaque forming cells and arthus reaction for humoral immunity, delayed hypersensitivity reaction of cell mediated immunity and carbon clearacnce for macrophage function. Erythrosine's effects were observed as follows; 1. Ery throsine showed no significant effects on circulating leulocyte counts and relative immunoorgan weight. 2. Erythrosine diminished IgM plaque forming cells. 3. Erythrosine decreased arthus reaction, in the dose dependent manner. 4. Erythrosine had no significant effect on delayed hypersensitivity. 5. Phagocytic and corrected phagocytic index were not affected. 6. Methemoglobin content was similar in the test and control groups.

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Effects of Low Fat Diet and Saturated Fat Supplementation on the Immune Status of BALB/c Mouse (저지방식이와 포화지방 첨가 식이가 BALB/c 마우스의 면역기능에 미치는 영향)

  • 박진순
    • Journal of Nutrition and Health
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    • v.26 no.5
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    • pp.578-585
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    • 1993
  • This study was performed to investigate effects of low fat diet and saturated fat supplementation on the function of the immune system. Forty male BALB/c mice average-weighing 15g were divided into two dietary groups: 0.7% safflower oil group and 4.3% beef tallow & 0.7% safflower oil group. Results are as follows; 1) Food intake, body weight, organ weight, agglutination test, differential white cell count and histological examination of spleen were not different in two dietary groups during the experimental period. 2) Delayed-type hypersensitive test of the mice fed 4.3% beef tallow & 0.7% safflower oil was significantly higher than that of the mice fed 0.7% safflower oil ($\alpha$=0.05). 3) Plaque forming cell was significantly reduced at 10th week compared to 7th week in both groups($\alpha$=0.05). Although there was no significant difference between two groups. 0.7% safflower oil groups showed slightly higher plaque forming cell than 4.3% beef tallow & 0.7% safflower oil group.

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Analysis of Impulse Force and Kinematic Factors of the Limbs during Stefan Holm's Take-off Phase and Penultimate Stride of High Jump (Stefan Holm의 높이뛰기 발구름 동작에서의 충격력과 상지와 하지 분절의 운동학적 분석)

  • Lee, Jin-Taek
    • Korean Journal of Applied Biomechanics
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    • v.21 no.1
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    • pp.97-105
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    • 2011
  • The purpose of this study was to investigate the kinetic factors of Stefan holm's take-off motion and provide the technical data. Collected data of the subject(height: 181 cm, weight: 71 kg, record: 230 cm) were used for the last two strides and take-off phase. The results were as follows: The vertical impulse force was 2044.8 N which was 2.49 times and the anterior-posterior impulse force was -1306.4 N which was 1.88 times of the subject's weight. The take-off leg angular velocities($\omega_x,\;\omega_y$) were switched drastically from clockwise to count clockwise direction between two-step touchdown and take-off. The highest jerk of the take-off foot was 368.97 m/s3 during the two step take-off and the take-off foot made an impact to the ground with 1225.07 m/s3 during the one step touchdown.

Regulation of Growth and Metabolic Activities of Chlorella fusca by Release Products of Some Aquatic Fungi (수생균의 분비물질에 의한 Chlorella fusca의 성장 및 대사조절)

  • Hassan, S.K.M.;Fadl-Allah, E.M.;Kobbia, I.A.;Shoulkamy, M.A.
    • The Korean Journal of Mycology
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    • v.18 no.4
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    • pp.181-190
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    • 1990
  • The growth and biochemical activities of Chlorella fusca were studied in the presence of different concentrations of either filtrates or mycelial mats of Saprolegnia ferax and Pythium graminicola. Low concentrations of both fungal filtrates exerted increase in total count, dry weight and in the biosynthesis of photosynthetic pigments, carbohydrates and nitrogen content. High concentrations showed inhibitory effect on both growth and biochemical activities of Chlorella fusca. Supplementation with different concentrations of dry mycelial mats of either fungi the culture of Chlorella showed elevation in biomass, dry weight, and biosynthesis of carbohydrates and nitrogen content especially at low concentrations. The contents of photosynthetic pigment were inhibited only at low concentrations. Neither the culture filtrate of Pythium nor Saprolegnia had cellulolytic activity, although polygalacturonase enzymes were detected, whereas chloroform-extract of both fungal filtrates showed blue spots under long wave light (366 nm).

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Characterization for Applying to Optimized Model of Flatform System Step Parts Material for Low-High Platform Railroad Vehicle (저상고상 철도차량용 승강시스템 스텝 부품 소재의 최적화 모델 적용을 위한 특성 평가)

  • Kwak, Hee-Man;Choi, Jung-Muk;Kim, Hyun-Dong;Park, Min-Heung;Kim, Chul-Su
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.1381-1388
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    • 2011
  • Recently, Because of weight lighting and tighten safety regulations of the railway vehicle railroad weight lighting and safety improvement technology is internationally required. Slide step for moving the passenger to high flatform in the railroad vehicle is recognized of important parts. However, Due to high price and weight, it is limited. In this research, In order to apply for railroad, it was redesigned to optimize part count and reduce the price and weight. By choosing honeycombcore as a part for enduring high weight and weight lighting, We produce honeycombpanel of sandwich structure which a different kind connected by using existing stainless(STS304)steel and thermo plasticity glue. Finally, we can find that honeycombpanel is suitable for weight lighting and high weight. As well as, with test result, we can prove that low-high platform railway system will be optimized, if steps are applied to honeycombpanel.

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