Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
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The Effects of Daecheongryoung-tang on Anti-weight Gain and Anti-hyperlipidemic in Obese Sprague Dawley Rat Induced by High Fat Diet

대청룡탕이 비만 유도 흰쥐의 체중 감량과 혈중지질농도 개선에 미치는 영향

  • Cho, Eun Jin (Namgaram Korean Medicine Clinic) ;
  • Yang, Seung Jeong (Department of Korean Gynecology, College of Oriental Medicine, Dongshin University) ;
  • Cho, Seong Hee (Department of Korean Gynecology, College of Oriental Medicine, Dongshin University)
  • 조은진 (남가람한의원) ;
  • 양승정 (동신대학교 한의과대학 한방부인과학교실) ;
  • 조성희 (동신대학교 한의과대학 한방부인과학교실)
  • Received : 2018.04.30
  • Accepted : 2018.06.25
  • Published : 2018.06.30
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Abstract

Objectives: The aim of this study is to investigate the effects of Daecheongryoung-tang (DCR) therapy on body weight, serum total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level and complete blood cell count of obese rats. Methods: 34 rats are divided into 4 groups, the rats in the normal group are 7 and the rats in the other group are 9 per group; Normal group (general fat diet and no medication), Control group (high-fat diet and no medication), DCR_L group (high-fat diet and DCR 250 mg medication) and DCR_H group (high-fat diet and DCR 500 mg medication). DCR is administrated for 6 weeks. Results: There is significant statistical difference between Control group and DCR-H group for the body weight, the total cholesterol, LDL cholesterol, triglyceride, free fatty acid level. Also, there is significant statistical difference among Control group, DCR_L group and DCR_H group for body weight, triglyceride, free fatty acid and phospholipid level. Conclusions: These results suggest that medication of DCR_L and DCR_H is effective for the treatment of obesity.

Keywords

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