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The Retrospective Study on Modified Fasting Therapy in Inpatients (절식요법을 시행한 입원환자의 후향적 연구)

  • Jung, Soon-Kwan;Kim, Dong-Eun;Yu, Deok-Seon;Yeom, Seung-Ryong;Song, Yung-Sun;Kwon, Young-Dal
    • Journal of Korean Medicine Rehabilitation
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    • v.18 no.4
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    • pp.171-187
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    • 2008
  • Objectives : The purpose of this study was to investigate the effects of modified fasting therapy on body composition, blood cell count and blood chemistry in inpatients. Methods : The modified fasting therapy program consists of three phases, a period of reducing food intakes, fasting and refeeding. Body weight, body composition, and the degree of obesity were estimated in before fasting therapy and after refeeding. Blood cell count and blood chemistry were estimated in before fasting therapy, before refeeding and after refeeding. Results : After modified fasting therapy, body weight, body fat mass, percent body fat, body mass index(BMI), body matabolic rate(BMR) and muscle mass was decreased significantly. WBC count and platelet count decreased significantly, RBC count and hemoglobin increased significantly and hematocrit was not changed significantly but within normal limit. AST and ALT increased significantly, especially patients group over BMI 25 within normal liver function. This study was not founded correlation between decreased muscle mass and increased liver function test. ALP, BUN, Total-cholesterol, and triglyceride decreased significantly. Creatinine increased significantly, but within normal limit. Sodium was not changed significantly, potassium decreased significantly but within normal limit. Conclusions : These results suggest that modified fasting therapy will be beneficial if several measures complement.

Weighted zero-inflated Poisson mixed model with an application to Medicaid utilization data

  • Lee, Sang Mee;Karrison, Theodore;Nocon, Robert S.;Huang, Elbert
    • Communications for Statistical Applications and Methods
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    • v.25 no.2
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    • pp.173-184
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    • 2018
  • In medical or public health research, it is common to encounter clustered or longitudinal count data that exhibit excess zeros. For example, health care utilization data often have a multi-modal distribution with excess zeroes as well as a multilevel structure where patients are nested within physicians and hospitals. To analyze this type of data, zero-inflated count models with mixed effects have been developed where a count response variable is assumed to be distributed as a mixture of a Poisson or negative binomial and a distribution with a point mass of zeros that include random effects. However, no study has considered a situation where data are also censored due to the finite nature of the observation period or follow-up. In this paper, we present a weighted version of zero-inflated Poisson model with random effects accounting for variable individual follow-up times. We suggested two different types of weight function. The performance of the proposed model is evaluated and compared to a standard zero-inflated mixed model through simulation studies. This approach is then applied to Medicaid data analysis.

Improving Productive and Reproductive Performance of Holstein Dairy Cows through Dry Period Management

  • Safa, S.;Soleimani, A.;Heravi Moussavi, A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.5
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    • pp.630-637
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    • 2013
  • To determine the effects of dry period (DP) length on milk yield, milk composition, some blood metabolites, complete blood count (CBC), body weight and score and follicular status, twenty five primiparous and multiparous Holstein cows were assigned to a completely randomized design with DP-60 (n = 13) and DP-20 (n = 12) dry period lengths. Cows in the DP-60 produced more milk, protein, SNF, serum non-esterified fatty acids (NEFA) and beta hydroxyl butyrate acid (BHBA) compared with cows in DP-20 ($p{\leq}0.05$). Serum glucose, blood urea nitrogen (BUN), urea, and glutamic oxaloacetic transaminase (GOT) were all similar among the treatments. Body Condition Score (BCS), body weight (BW), complete blood count (CBC) and health problems were similar between the treatments. Diameter of the first dominant follicle and diameter of the dominant follicle on d 14 were different among the treatments. Thus, results of this study showed that reducing the dry period length to DP-20 had a negative effect on milk production, milk composition and reproductive performance in Holstein dairy cows.

Experimental Study of Naesosan(內消散) on the Effects of Anti-Cancer (內消散의 抗癌效果에 관한 實驗的 硏究)

  • Park, Su-Yeon;Choe, Jeong-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.14 no.1
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    • pp.154-166
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    • 2001
  • Naesosan(NSS) has been used in Oriental Medicine as a drug that treated carbuncle and cellulitis. So, the purpose of this Study was to investigate effects of NSS on the cytotoxicity of cancer cell lines and lymphocytes in vitro, proliferation of Ll210 cells and lymphocytes in L1210 cells transplanted mice, improvement of blood count in Ll210 cells transplanted mice, tumor weight and body weight in sarcoma-180 cells transplanted mice, survival prolongation in sarcoma-180 cells transplanted mice. We used NSS extract with freeze-dried, 8wks-old male mice(balb/c and ICR mouse $18{\pm}2g$). Ll210 cell lines, and sarcoma-180 cell lines for this Study, The proliferation of cells was tested using a colorimetric tetrazoliun assay(MTT assay). The results of this Study were obtained as follows ; 1. NSS showed significantly cytotoxicitic effects of cancer cell lines, did not show cytotoxicitic effects of lymphocytes. 2, Proliferation of lymphocytes in L1210 cells transplanted mice did not effects by NSS. 3. NSS inhibited significantly the proliferation of L1210 cells in L1210 cells transplanted mice. 4. NSS improved significantly the blood count in Ll210 cells transplanted mice. 5. NSS increased significantly th body weight in sarcoma-180 cells transplanted mice. 6. NSS dereased significantly the tumor weight in sarcoma-180 cells transplanted mice. 7. NSS prolonged significantly the survival time in sarcoma-180 cells transplanted mice.

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Neoplastic and Hematological Effects of Endosulfan and Bleomycin in the Swiss Albino Mice Mus musculus

  • Sharmin, Tanjina;Ferdousi, Zennat;Islam, M. Saiful;Khan, M.Z.H.;Rahman, Atiqur
    • Applied Biological Chemistry
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    • v.51 no.4
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    • pp.294-298
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    • 2008
  • Effects of endosulfan (EN), an insecticide, and bleomycin (BL), an antibiotic, on the body weight in the normal mice, and the in vivo cell growth, tumor weight, and hematological parameters of the Ehrlich ascites carcinoma (EAC) cell-bearing Swiss albino mice Mus musculus were evaluated. EN and BL were respectively administered orally and intraperitoneally to the experimental mice; the control group consisted of EAC cell-bearing untreated mice only. EN reduced the body weight in normal mice, whereas BL resulted in a steady body weight compared to the control. EN increased the EAC cell count significantly by reducing the growth of normal viable cells. In contrast, BL reduced the cell count by increasing the proportion of viable cells in the body. The tumor weights induced by EN were significantly higher than those of the EAC control and the BL-treated animals. In comparisons with the control and the BL mice, hematological parameters such as hemoglobin (%) and the number of RBC and lymphocytes were lowered, while counts of WBC, neutrophils, and monocytes were elevated after EN treatments. These results show that BL is capable of reducing the EN-induced neoplastic and haematological alterations in the mice under laboratory conditions.

Effects of Probiotic and Prebiotic on Average Daily Gain, Fecal Shedding of Escherichia Coli, and Immune System Status in Newborn Female Calves

  • Roodposhti, Pezhman Mohamadi;Dabiri, Najafgholi
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.9
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    • pp.1255-1261
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    • 2012
  • Thirty two Holstein female calves (initial body weight = $40{\pm}3.0$ kg) were used to investigate the effects of probiotic and prebiotic on average daily gain (ADG), fecal E. coli count, white blood cell count, plasma IgG1 level and cell-mediated immune response to injection of phytohemagglutinin in suckling female calves. Calves were assigned randomly to one of the four treatments, including whole milk without additives (control), whole milk containing probiotic, whole milk containing prebiotic and whole milk containing probiotic and prebiotic (synbiotic). Average daily gain was greater in calves fed probiotic, prebiotic and synbiotic at weeks 6, 7 and 8 (p<0.05). E. coli count was significantly lower in calves fed probiotic, prebiotic and synbiotic on d 56 (p<0.05). There was no significant difference between treatments in blood samples and cell-mediated response. This study showed that addition of probiotic, prebiotic and combination of these additives to milk enhanced ADG and reduced fecal E. coli count in preruminant calves.

Ovarian Activity of Dromedary (Single Humped) Camel (Camelus dromedarius) in North-Eastern Nigeria

  • Yahaya, M.S.;Takahashi, J.;Matsuoka, S.;Alaku, O.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.6
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    • pp.868-870
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    • 1999
  • A total of 69 ovaries were collected from 345 camels slaughtered in Maiduguri abattoir, North-Eastern part of Nigeria, to study the influence of season on ovary weight and corpus luteum count in the dromedary (single humped) camel (Camelus dromedaries). Right ovary was significantly heavier (p<0.01) and had more follicular fluid than the left. Although corpus luteum count increased gradually throughout the study period, no camel had 3 active corpora lutea and only 53 out of the total number had two. Ovarian activity seem to be higher in the cold dry harmattan season, November/December, than during the warmer post rainy season, September/October. These periods can be exploited by farmers, especially peasants who rely heavily on natural mating, to obtain greater conception rates and reduce the chance of failure during mating.

Effect of Fermented Milk Products on the Growth and Blood Composition of Rats (발효유(醱酵乳) 제품(製品)이 흰쥐의 성장(成長) 및 혈액성분(血液成分)에 미치는 영향(影響))

  • Jang, Jung-Ok;Lee, Young-Soon
    • Journal of Nutrition and Health
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    • v.15 no.2
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    • pp.91-97
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    • 1982
  • In order to study the effects of commercial fermented milk and Lactobacillus juice on the growth and on blood composition of albino rats, these beverages were administered orally everyday and compared with the control rats. Experimental rats gained weight significantly compare with the control rats within the first week, but the body weights were comparable with the control during the next three weeks. WBC count was increased slightly in the experimental groups, but RBC count, hemoglobin and total serum protein contents were almost the same as that of the control group during the period. Fermented milk was effective in food efficiency ratio and fermented milk and lactobacillus juice were not influenced on any of internal organs weight.

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Estimation of Weight Distribution of Rockfall Block by Joint Measurement And Study on Its Application to Rockfall Simulation (절리조사결과에 의한 현장 낙석무게분포추정 및 추정결과의 낙석시뮬레이션 적용성 검토)

  • Kim, Dong-Hee;Ryu, Dong-Woo;Kim, Su-Chul;Yoon, Sang-Kil;Lee, Woo-Jin
    • Journal of the Korean Geotechnical Society
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    • v.23 no.11
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    • pp.67-76
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    • 2007
  • The characteristics of rockfall are determined by virtually all factors and conditions e.g. the physical figure of the slope such as inclination, height, roughness, the elemental figure of the slope such as vegetation and material deposited, and the shape and weight of the rockfall itself. Although it is one of the major factors to be considered in rockfall simulation, little attention has been given to the weight of the rockfall. And, since the size of the rockfall is dominated by joint spacing, the distribution of the rockfall block weight can be predicted as a function of the joint spacing. In this study, the weight distribution of rockfall was estimated by using the method of volumetric joint count, $J_{\nu}$, based on joint spacing, and $RQD-J_{\nu}$. The results indicate that the weight distributions were analogous in two methods, and the distribution was to be $75.3{\sim}76.7%$ for 200 kilograms or lesser, $15.0{\sim}16.6%$ for $200{\sim}400$ kilograms, and $6.7{\sim}9.7%$ for 400 kilograms or more, which show good matches with the actual on-site weight distribution. Therefore, the weight distribution of rockfall suggested in this paper is able to be considered as appropriate data for rockfall simulation.

A Study on a Algorithm of Gait Analysis and Step Count with Pressure Sensors (보행수 측정 및 보행패턴 분류 알고리즘)

  • Do, Ju-pyo;Choi, Dae-yeong;Kim, Dong-jun;Kim, Kyung-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.12
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    • pp.1810-1814
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    • 2017
  • This paper develops an approach to the algorithm of Gait pattern Analysis and step measurement with Multi-Pressure Sensors. The process of gait consists of 8 steps including stance and swing phase. As 3 parts of foot is supporting most of human weight, multiple pressure sensors are attached on the parts of foot: forefoot, big toe, heel. As 3 parts of foot is supporting most of human weight, multiple pressure sensors are attached on the parts of foot: forefoot, big toe, heel. normal gait proceed from heel, forefoot and big toe over time. While normal gait proceeds, values of heel, forefoot and big toe can be changed over time. So Each values of pressure sensors over time could discriminate whether it is normal or abnormal gait. Measuring Device consists of non-inverting amplifiers and low pass filter. Through timetable of values, normal gait pattern can be analyzed, because of supported weight of foot. Also, the peak value of pressure can judge whether it is walking or running. While people are running, insole of shoes is floating in the air on moment. Using this algorithm, gait analysis and step count can be measured.