• Title/Summary/Keyword: Cost-effective Benefits

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Effects of Autotransfusion Using Cell Saver in Cardiovascular Surgery (심혈관수술에서 cell saver를 이용한 자가수혈)

  • 구자홍
    • Journal of Chest Surgery
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    • v.26 no.4
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    • pp.255-259
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    • 1993
  • The efficacy of the autotransfusion system is a reducing the need of intraoperative and postoperative transfusion in cardiovascular surgery. Between January 1990 and December 1991, we experienced 23 cases of autotransfusion using Haemonetic Cell Saver in cardiovascular surgery [Experimental group]. Another 13 cases which were taken similiar operations without Cell Saver during same period [Control group]. The amounts of blood transfused are 4.23 1.84 units in Control group, 2.82 1.84 units in Experimental group. Postoperatively, both groups showed decreased platelet counts, mild prolongation of prothrombin and partial thromboplastin time compred to preoperative value [P<0.001], but there were no significant differences between two group [P=NS]. Plasma hemoglobin was markedly increased in Experimental group compared with Control group [p<0.05]. In Experimental group, amount of average processed blood by Cell Saver was 700ml of which composition was hemoglobin 17mg/dl, hematocrit 50.0%, RBC 5,590,000/ml, WBC 7500/ml, and platelet 40,000/ml. The culture of the processed blood revealed no growth of the organisms. Conclusively, Cell Saver autotransfusion system is a simple, safe, and cost effective method especially in the cases associated with massive bleeding. However, it requires familiarity with system, gentle manipulation of suction tip, and careful selection of candidates to obtain maximal benefits .

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Metabolic evaluation of children with global developmental delay

  • Eun, So-Hee;Hahn, Si Houn
    • Clinical and Experimental Pediatrics
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    • v.58 no.4
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    • pp.117-122
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    • 2015
  • Global developmental delay (GDD) is a relatively common early-onset chronic neurological condition, which may have prenatal, perinatal, postnatal, or undetermined causes. Family history, physical and neurological examinations, and detailed history of environmental risk factors might suggest a specific disease. However, diagnostic laboratory tests, brain imaging, and other evidence-based evaluations are necessary in most cases to elucidate the causes. Diagnosis of GDD has recently improved because of remarkable advances in genetic technology, but this is an exhaustive and expensive evaluation that may not lead to therapeutic benefits in the majority of GDD patients. Inborn metabolic errors are one of the main targets for the treatment of GDD, although only a small proportion of GDD patients have this type of error. Nevertheless, diagnosis is often challenging because the phenotypes of many genetic or metabolic diseases often overlap, and their clinical spectra are much broader than currently known. Appropriate and cost-effective strategies including up-to-date information for the early identification of the "treatable" causes of GDD are needed for the development of well-timed therapeutic applications with the potential to improve neurodevelopmental outcomes.

Development of the Mammalian Expression Vector System that can be Induced by IPTG and/or Lactose

  • Myung, Seung-Hyun;Park, Junghee;Han, Ji-Hye;Kim, Tae-Hyoung
    • Journal of Microbiology and Biotechnology
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    • v.30 no.8
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    • pp.1124-1131
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    • 2020
  • Techniques used for the regulation of gene expression facilitate studies of gene function and treatment of diseases via gene therapy. Many tools have been developed for the regulation of gene expression in mammalian cells. The Lac operon system induced with isopropyl β-D-1-thiogalactopyranoside (IPTG) is one of the employed inducible systems. IPTG mimics the molecular structure of allolactose and has a strong affinity for the corresponding repressor. IPTG is known to rapidly penetrate into mammalian cells and exhibits low toxicity. In the present study, we developed a new inducible expression system that could regulate the expression of genes in mammalian cells using IPTG. Here we confirm that unlike other vector systems based on the Lac operon, this expression system allows regulation of gene expression with lactose in the mammalian cells upon transfection. The co-treatment with IPTG and lactose could improve the regulatory efficiency of the specific target gene expression. The regulation of gene expression with lactose has several benefits. Lactose is safe in humans as compared to other chemical substances and is easily available, making this technique very cost-effective.

Comparison of Production Structure of Purse Seine Fishery in Korea and Norway (우리나라와 노르웨이의 선망어업 현황 및 생산구조 비교)

  • Kim, Dae-Young
    • Journal of Fisheries and Marine Sciences Education
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    • v.27 no.1
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    • pp.308-318
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    • 2015
  • In order to improve the competitiveness of Korean large purse seine fishery, the purpose of this study is to find out the problems and present the improvement of the production structure of Korean large purse seine fishery by comparing to the production structure of Norwegian purse seine fishery. Norwegian purse seine fishery has been operating labor and energy-saving systems through a single wire operation and avoiding fishing competition through the introduction of IVQ system with different types of fishing vessel and obtaining benefits from Leading fishery management integrated with fish pumps and cooling water systems. In contrast, our country has a large purse seine fishery issues such as high cost and low efficiency of production structures, the volatility of mackerel resources, the lack of leading fishery management after catching fishes, the reduction of fishing ground in accordance with the North East Asia EEZ system. To solve these problems, initiatives to improve the structure of our large purse seine fishery are as follows: First, Implementing the promotion of the effective immature fishes management and establishing Korea-China-Japan resource management system. Second, the promotion of reduction of fleet size, the review of possible single fishing operation, leading out to strengthen its competitiveness by switching to energy-efficient production systems through enhanced efforts at fisheries catches steps. Third, it is necessary to realize corporate through the diversification of business areas and the large-scale commercialization of production structure.

Type and Settlement System of Disputes in Electronic Commerce (전자상거래 분쟁의 유형과 해결제도)

  • 이강빈
    • Journal of Arbitration Studies
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    • v.11 no.1
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    • pp.217-245
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    • 2001
  • Like traditional commerce, disputes are bound to arise in the course of conducting an e-commerce transaction. At present of June 30, 2001, 259 cases of dispute on e-commerce have been applied for the mediation of Electronic Transaction Dispute Mediation Committee, types of them are 170 cases of delayed delivery of commodity, 21 cases of contract cancellation and refund, 16 cases of personal information protection, 16 cases of false and exaggerated advertisement, 14 cases of commodity defect. The settlement systems of e-commerce dispute are litigation and Alternative Dispute Resolution(ADR). ADR encompasses mediation, arbitration, and similar private tools for resolving disputes. ADR offers many perceived advantages. Speed of resolution and low cost are often cited as the primary benefits. Therfore e-commerce disputes may be settled more effectively by litigation. The settlement systems of e-commerce dispute by ADR are the mediation of Electronic Transaction Dispute Mediation Committee, the mediation of Consumer Dispute Mediation Commercial Arbitration Board, and the arbitration of Korean Commerical Arbitration Board. E-commerce sets up the probability that its merchants and customers will not exist in the same legal jurisdictions. The confusing application of laws and wide geographical dispersion of these parties will necessitate a faster and cheaper dispute resolution methodology. Therefore, online ADR may be effective for e-commerce dispute resolution. The examples of online ADR opetation are the cyber mediation of Electronic Transaction Dispute Resolution Committee, the cyber mediation of Korean Commercial Arbitration Board, the cyber mediation of Click N Settle, the online ADR of BBB online, and the cyber arbitration of virtual Magistrate.

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Awareness Regarding Risk Factors, Symptoms and Treatment Facilities for Cancer in Selected States of India

  • Raj, Sherin;Piang, Lam Khan;Nair, K.S.;Tiwari, V.K.;Kaur, Harneet;Singh, Bacchu
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.4057-4062
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    • 2012
  • Objective: To study the level of awareness and knowledge about cancers and associated risk factors among households in selected states of India. Methods: In the study 3070 households were interviewed from six states viz, West Bengal, Kerala, Madhya Pradesh, Rajasthan and Mizoram. Results: Knowledge of cancers other than those related to tobacco was very low (prostate 8%, colon 11% ) among the communities, with a poor awareness of warning signs and symptoms. The knowledge varied from state to state. It is found that the major source of information related to cancers was television (38%) followed by friends and relatives (36%). Only about 15 % of respondents had knowledge about cancer awareness camps organized in their districts but they did not have knowledge about the organizers of the camp. Findings suggested a strong need for strengthening of DCCP. Conclusion: It is important to create awareness among community through educational programs on cancer prevention, preventable cancer risk factors, benefits of early diagnosis, and availability of screening facilities. Integration of District Cancer Control activities with NRHM could be the most cost-effective strategy to prevent cancers and rural population.

Load Transferring Mechanism and Design Method of Effective Detailings for Steel Tube-Core Concrete Interaction in CFT Columns with Large-Section

  • Li, Yuanqi;Luo, Jinhui;Fu, Xueyi
    • International Journal of High-Rise Buildings
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    • v.7 no.3
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    • pp.223-232
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    • 2018
  • Two novel types of construction detailings, including using the distributive beam and the inner ring diaphragm in the joint between large-section CFT columns and outrigger truss to enhance the transferring efficiency of huge vertical load, and using the T-shaped stiffeners in the steel tube of large-section CFT columns to promote the local buckling capacity of steel tubes, were tested to investigate their working mechanism and design methods. Experimental results show that the co-working performance between steel tube and inner concrete could be significantly improved by setting the distributive beam and the inner ring diaphragm which can transfer the vertical load directly in the large-section CFT columns. Meanwhile, the T-shaped stiffeners are very helpful to improve the local bulking performance of steel tubes in the column components by the composite action of T-shaped stiffeners together with the core concrete under the range of flange of T-shaped stiffeners. These two approaches can result in a lower steel cost in comparison to normal steel reinforced concrete columns. Finally, a practical engineering case was introduced to illustrate the economy benefits achieved by using the two typical detailings.

Diagnostic Laparoscopy and Laparoscopic Diverting Sigmoid Loop Colostomy in Penetrating Extraperitoneal Rectal Injury: A Case Report

  • Jo, Young Goun;Park, Yun Chul;Kang, Wu Seong;Kim, Jung Chul;Park, Chan Yong
    • Journal of Trauma and Injury
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    • v.30 no.4
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    • pp.216-219
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    • 2017
  • Laparoscopy has been one of the most effective modalities in various surgical situations, although its use in trauma patients has some limitations. The benefits of laparoscopy include cost-effectiveness, shorter length of hospital stay, and less postoperative pain. This report describes diagnostic laparoscopy and laparoscopic diverting sigmoid loop colostomy in penetrating extraperitoneal rectal injury. A 41-year-old male presented with perineal pain following penetrating trauma caused by a tree limb. Computed tomography showed air density in the perirectal space and retroperitoneum. As his vital signs were stable, we performed diagnostic laparoscopy and confirmed no intraperitoneal perforation. Therefore, laparoscopic diverting sigmoid loop colostomy was performed. He was discharged without any complications despite underlying hepatitis C-related cirrhosis. Colostomy closure was performed 3 months later.

Customer Loyalty and Logistics Service Performance in Maritime Transport : A Literature Review and Conceptual Model

  • Jang, Hyun Mi;Kim, Sang Youl
    • Journal of Navigation and Port Research
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    • v.36 no.9
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    • pp.753-761
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    • 2012
  • To achieve a differential advantage over competitors and protect their long-term interest, shipping lines have striven to find ways to maintain an ongoing relationship with shippers which can be achieved by attaining their loyalty. The benefits of loyal shippers are potentially huge in that they generate long-term revenue streams as well as provide cost savings as compared with attracting new shippers. Logistics service provided by shipping lines is identified as one of the effective tools for building customer loyalty. However, in a review of the literature none of the studies examine how logistics service creates customer loyalty, particularly between shipping lines and shippers. Consequently, the overarching purpose of this paper is to extend knowledge on logistics service performance and its relationship with customer loyalty in the unique context of maritime transport by proposing a new conceptual model based on an extensive literature review. The major contribution is to offer a new insight into the complex relationships between those 'soft' concepts in the context of maritime transport.

Fabrication and Characterization of Electro-photonic Performance of Nanopatterned Organic Optoelectronics

  • Nil, Ri-Swi;Han, Ji-Yeong;Gwon, Hyeon-Geun;Lee, Gyu-Tae;Go, Du-Hyeon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.134.2-134.2
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    • 2014
  • Photonic crystal solar cells have the potential for addressing the disparate length scales in polymer photovoltaic materials, thereby confronting the major challenge in solar cell technology: efficiency. One must achieve simultaneously an efficient absorption of photons with effective carrier extraction. Unfortunately the two processes have opposing requirements. Efficient absorption of light calls for thicker PV active layers whereas carrier transport always benefits from thinner ones, and this dichotomy is at the heart of an efficiency/cost conundrum that has kept solar energy expensive relative to fossil fuels. This dichotomy persists over the entire solar spectrum but increasingly so near a semiconductor's band edge where absorption is weak. We report a 2-D, photonic crystal morphology that enhances the efficiency of organic photovoltaic cells relative to conventional planar cells. The morphology is developed by patterning an organic photoactive bulk heterojunction blend of Poly(3-(2-methyl-2-hexylcarboxylate) thiophene-co-thiophene) and PCBM via PRINT, a nano-embossing method that lends itself to large area fabrication of nanostructures. The photonic crystal cell morphology increases photocurrents generally, and particularly through the excitation of resonant modes near the band edge of the organic PV material. The device performance of the photonic crystal cell showed a nearly doubled increase in efficiency relative to conventional planar cell designs. Photonic crystals can also enhance performance of other optoelectronic devices including organic laser.

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