• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8503-8508
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• 2014

Background: After the WHO recommended HPV vaccination of the general population in 2009, government support of HPV vaccination programs was increased in many countries. However, this policy was not implemented in Korea due to perceived low cost-effectiveness. Thus, the aim of this study was to analyze the cost-utility of HPV vaccination programs targeted to high risk populations as compared to vaccination programs for the general population. Materials and Methods: Each study population was set to 100,000 people in a simulation study to determine the incremental cost-utility ratio (ICUR), then standard prevalence rates, cost, vaccination rates, vaccine efficacy, and the Quality-Adjusted Life-Years (QALYs) were applied to the analysis. In addition, sensitivity analysis was performed by assuming discounted vaccination cost. Results: In the socially vulnerable population, QALYs gained through HPV vaccination were higher than that of the general population (General population: 1,019, Socially vulnerable population: 5,582). The results of ICUR showed that the cost of HPV vaccination was higher for the general population than the socially vulnerable population. (General population: 52,279,255 KRW, Socially vulnerable population: 9,547,347 KRW). Compared with 24 million KRW/QALYs as the social threshold, vaccination of the general population was not cost-effective. In contrast, vaccination of the socially vulnerable population was strongly cost-effective. Conclusions: The results suggest the importance and necessity of government support of HPV vaccination programs targeted to socially vulnerable populations because a targeted approach is much more cost-effective. The implementation of government support for such vaccination programs is a critical strategy for decreasing the burden of HPV infection in Korea.

• Journal of Fisheries and Marine Sciences Education
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• v.21 no.2
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• pp.199-212
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• 2009

The purpose of this study is to analyze the cost-effectiveness analysis on on-line and off-line extra-curricula education(ECE). Based on a review of relevant literature, on-line ECE is defined as internet based learning, and off-line ECE is defined as on-site learning out of school such as private cram schools and private tutoring. The results of this study are as follows: First, sixty nine percent of the subjects were received ECE. Off-line ECE is more dominant than on-line ECE. Second, cost for off-line ECE is more expensive than on-line ECE. Third, off-line ECE is more effective than on-line ECE, when cost is ignored. Fourth, on-line ECE is more cost-effective than off-line ECE.

• Korean Management Science Review
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• v.22 no.1
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• pp.1-13
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• 2005

This paper proposed a quantitative evaluation method to measure the operational effectiveness of the local military manpower administrations. The proposed method compared the relative operational effectiveness level for 12 local military manpower administrations in Korea.. The method used the IDEA (imprecise Data Envelopment Analysis) model which Is able to measure relative operational effectiveness level, and also used two input variables (labor cost, operational cost) and three output variables (number of military applicants, number of civil application approved & processed, management accuracy level). Through the model output analysis, we presented the relative effectiveness scores, the reason for non-effectiveness, and the relationship between non-effective ness level and input/output variables for each local military manpower administration. We also presented a few recommendations how to improve the effectiveness level on particular local military manpower administration.

• Journal of Korean Medical Science
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• v.33 no.46
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• pp.304.1-304.7
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• 2018

Background: The Republic of Korea has a very low prevalence of human immunodeficiency virus (HIV) infection, but the number of new HIV diagnoses has steadily risen, strongly indicating a large number of undetected HIV infections. Thus, it is important for Korean public health authorities to adopt and encourage cost-effective HIV detection tools, such as rapid HIV screening tests. In this study, we aimed to evaluate the cost-effectiveness of enzyme-linked immunosorbent assays (ELISA) and rapid tests in a public health center (PHC) setting. Methods: We developed a decision analytic model to assess the per-examinee cost and the cost-effectiveness of identifying HIV patients in a PHC setting using two HIV testing strategies: conventional HIV screening by ELISA versus rapid HIV testing. Analysis was performed in two scenarios: HIV testing in an average-risk population and in a high-risk population. Results: Compared to the ELISA, the rapid test was cost-saving and cost-effective. The per-examinee cost was USD 1.61 with rapid testing versus USD 3.38 with ELISA in an average-risk population, and USD 4.77 with rapid testing versus USD 7.62 with ELISA in a high-risk population. The cost of identifying a previously undiagnosed HIV case was USD 26,974 with rapid testing versus USD 42,237 with ELISA in an average-risk population, and USD 153 with rapid testing versus USD 183 with ELISA in a high-risk population. Conclusion: Rapid testing would be more cost-effective than using conventional ELISA testing for identifying previously undiagnosed HIV-infected cases in Korea, a country with extremely low HIV prevalence.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.05a
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• pp.966-971
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• 2003

[ $\lceil\;Cost Effectiveness Analysis\;\rfloor$ ] has been widely used to evaluate effectiveness of R&D resources. But, almost of cost effectiveness evaluation systems have some problems, especially estimating method of effect on R&D project is very rough and imprecise. To solve this problem, we have designed new single effect evaluation system, which are able to apply the distribution of order statistics and to transform relative measure into absolute measure for getting single effect.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.11a
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• pp.21-24
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• 2003

$\ulcorner$Cost Effectiveness Analysis$\lrcorner$ has been widely used to evaluate the effectiveness of R＆D resources. But, almost of cost effectiveness evaluation systems have some problems, especially the cross effect among R＆D projects has not been considered. To solve this problem, we have designed a new $\ulcorner$Cross Effect Evaluation System(CEES)$\lrcorner$, which are able to estimate multi-effects and cross effects by completion time among several projects.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.6857-6862
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• 2015

Background: To identify the optimal cost effective strategy for the management of women having ASC-US who attended at King Chulalongkorn Memorial Hospital (KMCH). Design: An Economical Analysis based on a retrospective study. Subject: The women who were referred to the gynecological department due to screening result of ASC-US at King Chulalongkorn Memorial Hospital, a general and tertiary referral center in Bangkok Thailand, from Jan 2008 - Dec 2012. Materials and Methods: A decision tree-based was constructed to evaluate the cost effectiveness of three follow up strategies in the management of ASC-US results: repeat cytology, triage with HPV testing and immediate colposcopy. Each ASC-US woman made the decision of each strategy after receiving all details about this algorithm, advantages and disadvantages of each strategy from a doctor. The model compared the incremental costs per case of high-grade cervical intraepithelial neoplasia (CIN2+) detected as measured by incremental cost-effectiveness ratio (ICER). Results: From the provider's perspective, immediate colposcopy is the least costly strategy and also the most effective option among the three follow up strategies. Compared with HPV triage, repeat cytology triage is less costly than HPV triage, whereas the latter provides a more effective option at an incremental cost-effectiveness ratio (ICER) of 56,048 Baht per additional case of CIN 2+ detected. From the patient's perspective, the least costly and least effective is repeat cytology triage. Repeat colposcopy has an incremental cost-effectiveness (ICER) of 2,500 Baht per additional case of CIN2+ detected when compared to colposcopy. From the sensitivity analysis, immediate colposcopy triage is no longer cost effective when the cost exceeds 2,250 Baht or the cost of cytology is less than 50 Baht (1USD = 31.58 THB). Conclusions: In women with ASC-US cytology, colposcopy is more cost-effective than repeat cytology or triage with HPV testing for both provider and patient perspectives.

• Pediatric Infection and Vaccine
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• v.15 no.1
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• pp.20-29
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• 2008

The basis of the economic evaluation of vaccination is the balance between the use of the resources (input) and the improvements that result from the vaccination (output). Techniques used for economic evaluation of vaccination are cost analysis, cost-minimization analysis, cost-effectiveness analysis, cost-utility analysis and cost-benefit analysis. Cost analysis seeks to characterize the costs of a given vaccination program. Cost-effective analysis is to helps policy-makers decide on the best use of allocated resources, whether cost-benefit analysis is to helps policy-makers decide on the overall allocation of resources. Cost-utility analysis is a specific form of cost-effective analysis in which outcomes are reduced to a common denominator such as the quality-adjusted life year (QALY) or disability-adjusted life year (DALY). Many economic analyses have been conducted on vaccines in the world, but there have been a little studies on economic evaluation on vaccines in Korea. This paper reviewed the methodology used to economic evaluation on vaccines and immunizations and addressed some examples of the methods.

• Journal of the Korea Institute of Military Science and Technology
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• v.13 no.1
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• pp.84-90
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• 2010

Korean army currently considers the development of the new generation MLRS(Multiple Launcher Rocket System) as a new alternative, which responses on the renovation of the artillery and future battlefield environment. This study suggests that it presents cost-effectiveness of MLRS based on the Analytic Hierarchy Process and Parametric Estimating(PRICE H). According to this study, the cost-effectiveness of new generation MLRS presented that alternative A is 2.30 times and alternative B is 1.70 times, which are better than currently operating M270A1. Therefore, The best acquisition is alternative A that launcher is carried on currently operating 10ton standard truck but final acquisition alternative should be politically decided to consider viability of operator, performance and the latest of equipment.

• YAKHAK HOEJI
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• v.50 no.2
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• pp.70-77
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• 2006

A cost effective analysis was performed for comparing leflunomide+methotrexate, etanercept monotherapy and etanercept+methotrexate for 6 months. For the patients with methotrexate-resistant RA, ACR20 data were extracted from the published clinical trials searched from Pubmed. The direct medical cost was estimated based on ACR guideline and Korean National Health Insurance reimbursement. Combination therapy of etanercept+methotrexate was found to be more cost-effective than etanercept monotherapy, which meant it was a better therapeutic strategy for methotrexate- resistant RA.