• Journal of Electrical Engineering and Technology
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• 제10권5호
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• pp.1930-1939
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• 2015

Wind power planning aims to locate and size wind farms optimally. Traditionally, wind power planners tend to choose the wind farms with the richest wind resources to maximize the energy benefit. However, the capacity benefit of wind power should also be considered in large-scale clustered wind farm planning because the correlation among the wind farms exerts an obvious influence on the capacity benefit brought about by the combined wind power. This paper proposes a planning model considering both the energy and the capacity benefit of the wind farms. The capacity benefit is evaluated by the wind power capacity credit. The Ordinal Optimization (OO) Theory, capable of handling problems with non-analytical forms, is applied to address the model. To verify the feasibility and advantages of the model, the proposed model is compared with a widely used genetic algorithm (GA) via a modified IEEE RTS-79 system and the real world case of Ningxia, China. The results show that the diversity of the wind farm enhances the capacity credit of wind power.

• 대한의용생체공학회:의공학회지
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• 제38권3호
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• pp.123-128
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• 2017

Background and aims: The KCNQ1 S140G mutation involved in $I_{ks}$ channel is a typical gene mutation affecting atrial fibrillation. However, despite the possibility that the S140G gene mutation may affect not only atrial but also ventricular action potential shape and ventricular responses, there is a lack of research on the relationship between this mutation and ventricular fibrillation. Therefore, in this study, we analyzed the correlation and the influence of the KCNQ1 S140G mutant gene on ventricular fibrillation through computer simulation studies. Method: This study simulated a 3-dimensional ventricular model of the wild type(WT) and the S140G mutant conditions. It was performed by dividing into normal sinus rhythm simulation and reentrant wave propagation simulation. For the sinus rhythm, a ventricular model with Purkinje fiber was used. For the reentrant propagation simulation, a ventricular model was used to confirm the occurrence of spiral wave using S1-S2 protocol. Results: The result showed that 41% shortening of action potential duration(APD) was observed due to augmented $I_{ks}$ current in S140G mutation group. The shortened APD contributed to reduce wavelength 39% in sinus rhythm simulation. The shortened wavelength in cardiac tissue allowed re-entrant circuits to form and increased the probability of sustaining ventricular fibrillation, while ventricular electrical propagation with normal wavelength(20.8 cm in wild type) are unlikely to initiate re-entry. Conclusion: In conclusion, KCNQ1 S140G mutation can reduce the threshold of the re-entrant wave substrate in ventricular cells, increasing the spatial vulnerability of tissue and the sensitivity of the fibrillation. That is, S140G mutation can induce ventricular fibrillation easily. It means that S140G mutant can increase the risk of arrhythmias such as cardiac arrest due to heart failure.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제35권1호
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• pp.1-12
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• 2013

Purpose: Vascular endothelial growth factor (VEGF)-C and its tyrosine kinase receptor, VEGF receptor (VEGFR)-3 are recently known to have lymphangiogenic activities in various tumor types. In this study, we determined whether the expression of lymphangiogenic factors correlate with nodal metastasis or survival in a nude mouse model of oral squamous cell carcinoma (OSCC). Methods: Three OSCC cells (KB, SCC4, SCC9) were xenografted into the right mandibular gland of athymic nude mice. The mice were followed for tumor development and growth, and the mice were sacrificed when they had lost more than 20% of their initial body weight, or the diameter of the induced tumor exceeds 20 mm. After necropsy, the murine tumors were examined histologically and radiologically (micro-positron emission tomography computed tomography) for regional or distant metastasis. We performed immunohistochemical assays with anti-VEGF-C, VEGFR-3, CD105, and D2-40 antibodies. Immunofluorescence double staining for LYVE-1/CD31 was also performed. To quantify the VEGF-C and VEGFR-3 level in the cancer tissue, Western blotting was performed. Finally, we determined the correlation between the degree of expression of VEGF-C/VEGFR-3 and the mean survival time. Results: OSCC tumor cells into the mandibular gland of the nude mice successfully resulted in the formation of recapitulating orthotopic tumor. Tumor cells of the induced tumor did not express VEGF-C. VEGF-C/VEGFR-3 expression was mainly distributed in the endothelial cells of the stromal area. There were no correlation between the degree of expression of VEGF-C/VEGFR-3 and the mean survival time of mice injected with different OSCC cell lines. Conclusion: An recapitulating orthotopic model of OSCC in nude mice was established, which copies the cervical nodal metastasis of human OSCC. Overexpression of lymphangiogenic factors seems to have no effect on survival of hosts in this in vivo experiment.

• 한국산학기술학회논문지
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• 제14권11호
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• pp.5771-5777
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• 2013

최근 만성질환의 증대로 질병의 지속적인 관리에 대한 필요성이 대두되고 있으나 개인 맞춤형 식품섭취와 관련한 분석 연구는 미비하다. 본 연구에서 제시한 당뇨병 발생 위험도 분석 모델은 기존 상품 선호도 연구를 통해 검증된 유사도평가 방법인 피어슨 상관계수 산출을 이용하여 식품 선호도를 산출하고, 유병율 분석 연구 등에 활용된 로지스틱 회귀분석 방법을 이용하여 당뇨병발생 위험도를 제시하였다. 모델의 유의성 평가를 위해 당뇨 진단을 받은 환자 52명(남자: 22명, 여자: 30, 평균연령: 57(${\pm}13.2$)세)과 비교군과 비슷한 연령을 조건으로 무작위 추출된 52명(남자: 17명, 여자: 35, 평균연령: 58(${\pm}9.4$)세)의 t-검정을 통해 0.05 수준에서 유의함을 검증하였다. 이를 통해 식품섭취빈도에 따른 당뇨병 발생 위험도에 차이가 있음(p=0.046)을 확인할 수 있었다. 이 모델을 기반으로 분석된 정보는 스마트폰이나 웹을 이용한 개인 건강관리 시스템에 적용을 통해 새로운 개인 맞춤형 건강관리 방법으로 제시될 수 있다.

• Journal of Welding and Joining
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• 제17권4호
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• pp.85-92
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• 1999

In GMAW, the spatter is generated because of the variation of the arc state. If the arc state is quantitatively assessed, the control method to make the spatter be reduced is able to develop. This study was attempted to develop the optimal model that could estimate the arc state quantitatively. To do this, the generated spatters was captured under the limited welding conditions, and the waveforms of the arc voltage and of the welding current were collected. From the collected waveforms, the waveform factors and their standard deviations were produced, and the linear and non-linear regression models constituted using the factors and their standard deviations are proposed to estimate the arc state. the performance test to the proposed models was practiced. Obtained results are as follow. From the results of correlation analysis between the factors and the amount of the generated spatters, the standard deviations of the waveform factors have more the multiple regression coefficients than the waveform factors. Because the correlation coefficient between T and {TEX}$T_{a}${/TEX}, and s[T] and s[{TEX}$T_{a}${/TEX}] was nearly one, it was found that these factors have the same effect to the spatter generation. In the regression models to estimate the arc state, it was fond that the linear and the non linear models were also consisted of similar factors. In addition, the linear regression model was assessed the optimal model for estimating the arc state because the variance of data was narrow and multiple regression coefficient was highest among the models. But in the welding conditions which the amount of the generated spatters were small, it was found that the non linear regression model had better the estimation performance for the spatter generation than the linear.

• 환경영향평가
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• 제12권2호
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• pp.87-98
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• 2003

The main purpose of this study is to propose the integrated assessment model for the rational and effective selection of proposed sites in National Trust (NT) and conserve the ruined natural environment by excessive land development. The results of this study are as follows; 1) The specialists thought that rare and endangered species were very important in plant and animal, in case of landscape and environment, naturality and water quality were too important. 2) In the result of the correlation measure on the indicator of assessment, 'erosion of soil'and 'air pollutant'was highly correlative. Secondly, 'suspended solids' and 'erosion of soil'was high correlation. 3) In the result of forming the factors into the integrated indicators, they were classified into conditional, stable, valuable and potential factors and the purpose of this formation is to evaluate proposed sites in NT objectively and rationally with organic assessment. 4) In the integrated assessment model, the degree of explanation was observed approximately 36.4% and the important factor was the conditional factor, but we have to consider all factors for the effective and objective assessment. Therefore we organically have to apply and use them for the assessment of proposed sites in NT. It turns out to offer raw data on the land conservation and carry out the role of the instrument of measurement. As for future directions, the follow are proposed: 1) adaptation of real proposed site, 2) verification of effect and problem, 3) practical survey for diverse types as mountain, coast and inland.

• 산업경영시스템학회지
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• 제41권1호
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• pp.84-93
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• 2018

In this paper, we propose an Elman recurrent neural network to predict and analyze a time series of power energy consumption. To this end, we consider the volatility of the time series and apply the sample variance and the detrended fluctuation analyses to the volatilities. We demonstrate that there exists a correlation in the time series of the volatilities, which suggests that the power consumption time series contain a non-negligible amount of the non-linear correlation. Based on this finding, we adopt the Elman recurrent neural network as the model for the prediction of the power consumption. As the simplest form of the recurrent network, the Elman network is designed to learn sequential or time-varying pattern and could predict learned series of values. The Elman network has a layer of "context units" in addition to a standard feedforward network. By adjusting two parameters in the model and performing the cross validation, we demonstrated that the proposed model predicts the power consumption with the relative errors and the average errors in the range of 2%~5% and 3kWh~8kWh, respectively. To further confirm the experimental results, we performed two types of the cross validations designed for the time series data. We also support the validity of the model by analyzing the multi-step forecasting. We found that the prediction errors tend to be saturated although they increase as the prediction time step increases. The results of this study can be used to the energy management system in terms of the effective control of the cross usage of the electric and the gas energies.

• 한국시뮬레이션학회논문지
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• 제20권3호
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• pp.59-67
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• 2011

본 논문에서는 오류 검출을 위해 소프트웨어 오류 추정 기법을 활용하여 항공무장 시스템인 공대지 사격의 오류 요인을 분석하기 위한 모델을 제시하고 모델을 기반으로 오류 요인 영향을 분석하였다. 선행 연구에서는 공대지 무기체계의 정확도에 영향을 미치는 오류 요소를 분석하고 결함위치추정 기법인 FBEL(Factor-based Error Localization) 기법을 제안하였으며 실사격 자료에 적용하여 오류 요소를 분석하였다. 그러나 다양한 요인 중 하나의 요인인 정확도를 고정하여 적용하므로 다양한 사격 정확도 변화에 따른 사격 오류 발생 요소와의 상관관계는 밝히지 못하였다. 본 연구에서는 사격 오류 요소의 상관관계 분석을 통하여 보다 세밀한 오류 분석 모델을 제시하고 시간과 비용이 제한적이거나 테스트 케이스가 적은 상태에서 오류 발생 가능 요소를 추정하는 방법을 제안한다. 제안된 방법은 실사격 자료를 이용한 시뮬레이션을 통해 그 효용성을 입증하였으며, 무기체계 공대지 시험평가에서 어떤 요소들이 정확도에 영향을 미치는 지를 분석하는데 성공적으로 활용될 수 있음을 보였다.

• Journal of the Korean Data and Information Science Society
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• 제25권5호
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• pp.1025-1038
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• 2014

가족 자료를 활용한 연속형 표현형의 전장유전체분석 (genome-wide association analysis)은 주로 선형혼합모형을 이용하며, 분산공분산행렬은 가족 구성원간의 유전적 거리를 고려하여 결정된다. 그러나 가족 구성원들의 표현형의 유사성은 유전적 요인과 환경적 요인에 의하여 발생함에도 불구하고, 표현형의 유사성은 단지 유전적 요인에 의해서 발생한다고 가정한다. 예를 들어 키의 경우 부부 사이에 양의 상관관계가 존재하나 유전적 요인만 고려하여 독립으로 가정한다. 선형혼합 모형에서 분산공분산 구조를 잘못 가정하는 경우, 검정통계량의 1종 혹은 2종의 오류를 적절히 관리할 수 없다. 본 논문에서는 다양한 유형의 분산공분산구조를 가정할 수 있는 선형혼합모형과 이를 기반으로 한 검정통계량을 제안하였다. 모의실험을 통하여 제안한 방법이 기존의 모형보다 통계적 검정력이 우수함을 확인하였다. 또한 체질량지수 (body mass index; BMI)의 전장유전체 분석에 적용하여 기존에 알려지지 않은 새로운 원인 유전자를 규명하였다.

• 한국정보전자통신기술학회논문지
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• 제12권3호
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• pp.192-200
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• 2019

본 연구에서는 해외직접구매와 해외직접판매와 거시경제변수 간의 인과관계를 도출하고 공적분 검정, 충격반응을 이용하여 인과관계를 실증분석하였다. 실증분석에 이용된 모형은 벡터오차수정모형(vector error correlation model)이고, 거시경제변수인 소비자물가지수, GDP를 이용하였고, 전자상거래변수로는 해외직접구매, 해외직접판매, 온라인쇼핑액을 이용하였다. 실증분석결과에 따르면, 해외직접구매는 소비자물가지수와 인과관계가 있고, GDP는 해외직접판매, 온라인쇼핑액과 각각 인과관계가 있는 것으로 나타났다. VECM의 충격반응분석 결과에 따르면, 해외직접구매는 소비자물가지수와 GDP에는 긍정적인 영향을 미치지만, 해외직접판매는 소비자물가지수와 GDP에 부정적인 영향을 미치는 것으로 나타났다. 그리고 해외직접구매와 해외직접판매 모두 온라인쇼핑액에 부정적인 영향을 미치지만, 해외직접구매가 온라인쇼핑액에 더 큰 부정적인 영향을 미치는 것으로 나타났다.