• Journal of Preventive Medicine and Public Health
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• 제49권1호
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• pp.18-22
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• 2016

Ethical considerations are essential in planning for and responding to outbreaks of infectious diseases. During the outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in the Republic of Korea in 2015, serious challenges emerged regarding important ethical issues, such as transparency and the protection of privacy. The development of bioethics in Korea has been influenced by individualistic perspectives applied in clinical contexts, leading to a paucity of ethical perspectives relevant to population-level phenomena such as outbreaks. Alternative theories of public health ethics include the perspectives of relational autonomy and the patient as victim and vector. Public health actions need to incorporate clear and systematic procedures founded upon ethical principles. The MERS-CoV epidemic in Korea created significant public support for more aggressive early interventions in future outbreaks. This trend makes it all the more imperative for ethical principles and procedures to be implemented in future planning and responses to outbreaks in order to promote perceptions of legitimacy and civic participation.

• Advances in Computational Design
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• 제7권4호
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• pp.345-369
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• 2022

Infectious disease emergency hospitals are usually temporarily built during the pneumonia epidemic with higher requirements regarding diagnosis and treatment efficiency, hygiene and safety, and infection control.This study aims to identify how the Building Information Modeling (BIM) + Industrialized Building System (IBS) approach could rapidly deliver an infectious disease hospital and develop site epidemic spreading algorithms. Coronavirus-19 pneumonia construction site spreading algorithm model mind map and block diagram of the construction site epidemic spreading algorithm model were developed. BIM+IBS approach could maximize the repetition of reinforced components and reduce the number of particular components. Huoshenshan Hospital adopted IBS and BIM in the construction, which reduced the workload of on-site operations and avoided later rectification. BIM+IBS integrated information on building materials, building planning, building participants, and construction machinery, and realized construction visualization control and parametric design. The delivery of Huoshenshan Hospital was during the most critical period of the Coronavirus-19 pneumonia epidemic. The development of a construction site epidemic spreading algorithm provided theoretical and numerical support for prevention. The agent-based analysis on hospital evacuation observed "arched" congestion formed at the evacuation exit, indicating behavioral blindness caused by fear in emergencies.

• Journal of Preventive Medicine and Public Health
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• 제53권2호
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• pp.65-66
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• 2020

• 대한수의학회지
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• 제38권3호
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• pp.581-588
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• 1998

Eight monoclonal antibodies(MAbs) against bovine coronavirus(BCV) were produced and characterized. Three MAbs(1G9, 4H12, 5C1) specific to the S glycoprotein and two HE glycoprotein-specific MAbs(2A5, 5G4) were found to neutralize the BCV in fluorescence focus neutralization(FFN) test. Two HE-specific MAbs from the neutralizing MAbs inhibited the hemagglutinating activity of the BCV. None of the N protein-specific MAbs(1C1, 5A12, 6H1) neutralized the virus infectivity. Bovine coronavirus and mouse hepatitis virus, which belong to group II coronaviruses, were differentiated from other groups of coronaviruses(porcine transmissible gastroenteritis virus, porcine epidemic diarrhea virus, canine coronavirus) by all MAbs in fluorescence antibody test(FA), but not in FFN test.

• Journal of Preventive Medicine and Public Health
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• 제48권6호
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• pp.277-279
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• 2015

Contact monitoring is an essential component of the public health response to a Middle East respiratory syndrome coronavirus outbreak, and is required for an effective quarantine to contain the epidemic. The timeliness of a quarantine is associated with its effectiveness. This paper provides a conceptual framework to describe the process of contact monitoring, and proposes a new measure called the "timely quarantined proportion" as a tool to assess the adequacy of a public health response.

• Korean Journal of Radiology
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• 제21권10호
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• pp.1161-1164
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• 2020

The epidemic of 2019 novel coronavirus, later named as coronavirus disease (COVID-19), began in Wuhan, China in December 2019 and has spread rapidly worldwide. Early diagnosis is crucial for the management of the patients with COVID-19, but the gold standard diagnostic test for this infection, the reverse transcriptase polymerase chain reaction, has a low sensitivity and an increased turnaround time. In this scenario, chest computed tomography (CT) could play a key role for an early diagnosis of COVID-19 pneumonia. Here, we have reported a confirmed case of COVID-19 with an atypical CT presentation showing a "double halo sign," which we believe represents the pathological spectrum of this viral pneumonia.

• 정보관리학회지
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• 제32권4호
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• pp.273-287
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• 2015

본 연구는 국민들에게 불안감을 야기하고 전반적인 사회활동을 위축시키는 메르스와 같은 질병의 유행이 공공도서관의 이용에 어떠한 영향을 주는지 알아보고자 하였다. 이를 위해 국립세종도서관에 위치하고 있는 "공공도서관 빅데이터 수집 및 분석 플랫폼"을 통해 전국 303개 공공도서관에서 수집된 18,711,453건의 대출기록을 분석하였다. 분석 결과는 다음과 같다. 첫째, 메르스가 유행했던 2015년도는 64,645.05권으로 2014년보다 하루 평균 6,300권 가량 대출책수가 감소하였다. 둘째, 2014년의 경우 7월 5일부터 8월 19일까지의 일평균 대출책수가 4월 4일부터 5월 19일까지와 5월 20일부터 7월 4일까지보다 많은 것으로 나타났다. 이는 학생들의 여름방학이 공공도서관의 대출책수 증가에 영향을 주었을 것으로 파악할 수 있다. 셋째, 메르스가 발생했던 2015년의 경우 메르스 유행 후 기간의 일평균 대출책수가 메르스 유행기간인 5월 20일부터 7월 4일까지보다 많은 것으로 나타났으나 메르스 유행 전 기간과는 유의한 차이가 존재하지 않았다. 넷째, 2014년과 2015년의 메르스 유행 전 기간의 일평균 대출책수와 2014년과 2015년의 메르스 유행 기간의 일평균 대출책수에는 유의한 차이가 없었으나, 2014년과 2015년의 메르스 유행 후 기간의 일평균 대출책수에서는 유의한 차이가 있었다. 연구 결과 국민들에게 불안감을 가져다 준 메르스는 질병의 유행 기간 보다는 오히려 유행 후 기간 동안 공공도서관의 일평균 대출책수에 영향을 주었음을 확인할 수 있었다.

• 대한한방소아과학회지
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• 제35권4호
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• pp.16-33
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• 2021

Objectives This study aims to provide directions for future Korean pediatric medicine treatment and researches by analyzing the characteristics of diseases of Korean pediatric outpatients before and after the COVID-19 epidemic. Methods We analyzed the medical records of 10,868 new patients aged 0-18 who visited the Korean pediatrics at Kyung Hee university hospital from January 1, 2019 to June 30, 2021. All patients were divided into 2 groups; patients who visited from January 1, 2019 to December 31, 2019, before the coronavirus epidemic, and patients who visited from January 1, 2020 to June 30, 2021, after the coronavirus epidemic. Within the two groups, the diagnosis distribution was performed for the entire population, by gender and by age group. Diagnoses were classified as allergy, growth, gastrointestinal, respiratory, general body supplementation, neuropsychiatric, skin, urogenital, musculoskeletal, and other systems. Results According to the comparative analysis results of before and after the COVID epidemic, there was a decreasing trend of diagnoses in relates to allergy, respiratory, urogenital, musculoskeletal system. On the other side, there was an increasing trend in gastrointestinal, general body supplementation, growth, neuropsychiatric, skin and other system. Changes in diagnosis based on gender and age group will be described below. Conclusions This study analyzed the characteristics of diseases of Korean pediatric outpatients before and after the COVID-19 epidemic, and suggested the direction of future Korean medicine treatment and researches for pediatrics. Also, this study aimed to propose proper treatments for children by showing the role of Korean pediatric medicine related to growth and development of children during the epidemic. However, this study has limitations such as failure to track the long-term impact of COVID-19. Thus, long term follow-up studies are needed to show the effect of COVID-19 on Korean pediatric medicine.

• Clinical and Experimental Pediatrics
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• 제63권12호
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• pp.477-482
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• 2020

The childhood obesity pandemic has emerged as an important public health problem in many countries. Obese children are likely to become obese adults, and adult obesity is associated with an increased risk of morbidity. Therefore, controlling the childhood obesity epidemic has become a top public health priority worldwide. The current coronavirus disease 2019 (COVID-19) pandemic may significantly impede this important mission and constitute an unprecedented tragedy in the global battle against childhood obesity. This manuscript presents evidence that the COVID-19 pandemic will aggravate the childhood obesity epidemic and lead to significant weight gain in school children by creating an unprecedented obesogenic environment. Within the last few months, many countries took uncompromising measures in response to the COVID-19 pandemic, including school closures and quarantine. While these steps are often necessary to ensure infection control, they may have a significant negative effect on children's mental and physical health. Physical, nutritional, and psychosocial factors that promote obesity in children during this special situation complementarily contribute to an unprecedented obesogenic environment. Large-scale quarantine and home confinement will impose new and unfamiliar stressors on children, thereby worsening the childhood obesity epidemic. Most importantly, adverse childhood events resulting from a predicted increase in domestic violence within the next few months will significantly contribute to this concern. The scenario presented in this review is of paramount public health importance and must be considered during future pandemic planning. Involved stakeholders, including governments, schools, and families, must make all possible efforts to minimize the impact of the COVID-19 epidemic on childhood obesity.

• 대한수의학회지
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• 제34권2호
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• pp.321-326
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• 1994

돼지 유행성 설사 바이러스(KPEDV-9)주를 이용하여 세포내 증식성을 비롯한 혈청학적 역학조사를 수행하였던 바 다음의 결과를 얻었다. 돼지 유행성 설사바이러스 국내 분리주는 Vero 세포에 연속계대시 증식성이 증가되었으며 90대 계대시 $10^{5.5}TCID_{50}/ml$의 역가를 나타내었다. 조직배양 순화주를 이용하여 간염세포내에서 20Kb 이상의 RNA가 존재함을 확인할수 있었으며 전자현미경 검사시 5~10nm의 외피항원 및 80~300nm크기의 coronavirus특징을 나타내었다. 설사증상을 나타내는 돼지의 장가검재료를 이용하여 유행성 설사 바이러스의 감염실태를 조사하였던 바 18%에 상당하는 감염 양성율을 확인하였으며 ELISA법에 의한 항체검사결과 전국적으로 약 45%의 항체 양성율을 나타내었다.