• Title/Summary/Keyword: Coronary arteries

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Vascular health late after Kawasaki disease: implications for accelerated atherosclerosis

  • Cheung, Yiu-Fai
    • Clinical and Experimental Pediatrics
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    • v.57 no.11
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    • pp.472-478
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    • 2014
  • Kawasaki disease (KD), an acute vasculitis that primarily affects young children, is the most common acquired paediatric cardiovascular disease in developed countries. While sequelae of arterial inflammation in the acute phase of KD are well documented, its late effects on vascular health are increasingly unveiled. Late vascular dysfunction is characterized by structural alterations and functional impairment in term of arterial stiffening and endothelial dysfunction and shown to involve both coronary and systemic arteries. Further evidence suggests that continuous low grade inflammation and ongoing active remodeling of coronary arterial lesions occur late after acute illness and may play a role in structural and functional alterations of the arteries. Potential importance of genetic modulation on vascular health late after KD is implicated by associations between mannose binding lectin and inflammatory gene polymorphisms with severity of peripheral arterial stiffening and carotid intima-media thickening. The changes in cholesterol and lipoproteins levels late after KD further appear similar to those proposed to be atherogenic. While data on adverse vascular health are less controversial in patients with persistent or regressed coronary arterial aneurysms, data appear conflicting in individuals with no coronary arterial involvements or only transient coronary ectasia. Notwithstanding, concerns have been raised with regard to predisposition of KD in childhood to accelerated atherosclerosis in adulthood. Until further evidence-based data are available, however, it remains important to assess and monitor cardiovascular risk factors and to promote cardiovascular health in children with a history of KD in the long term.

Acute Limb Ischemia and Coronary Artery Disease in a Case of Kimura's Disease

  • Heo, Woon;Jun, Hee Jae;Kang, Do Kyun;Min, Ho-Ki;Hwang, Youn-Ho;Kim, Ji Yong;Nam, Kyung Han
    • Journal of Chest Surgery
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    • v.50 no.2
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    • pp.114-118
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    • 2017
  • Kimura disease (KD) is an immune-mediated chronic inflammatory disease of unknown etiology. KD has many complications associated with hypereosinophilia, including various forms of allergic reactions and eosinophilic lung disease. Additionally, hypereosinophilia is associated with hypercoagulability, which may lead to thromboembolic events. A 36-year-old man with KD presented with acute limb ischemia and coronary artery occlusion. He underwent thrombectomy, partial endarterectomy of both popliteal arteries, and coronary artery stent insertion. KD is a systemic disease that affects many organs and presents with thromboembolism and vasculitis. In a patient with KD, physicians should evaluate the vascular system, including the coronary arteries.

Conduits for Coronary Bypass: Arteries Other Than the Internal Thoracic Artery's

  • Barner, Hendrick B.
    • Journal of Chest Surgery
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    • v.46 no.3
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    • pp.165-177
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    • 2013
  • This is the third in a series on coronary artery bypass which reviews three alternative arterial conduits. The radial artery has become the most widely used of the three and accumulating experience demonstrates better patency at 10 years versus saphenous vein. Drawbacks are a long incision on the forearm, the propensity for spasm and persistent sensory disturbance in about 10%. The first is answered by endoscopic harvest which may yield a shorter conduit but reduces sensory nerve injury. Spasm is managed pharmacologically and by less harvest trauma. The gastroepiploic artery is used in situ and free and although the abdominal cavity is entered complications are minimal and patency compares favorably with the radial artery. Use of the inferior epigastric artery remains minimal and its similar length often requires composite use but limited patency data are supportive. Other arteries have had rare use and this is unlikely to change because the three presented here have significant advantages and acceptance.

Intractable Coronary Spasm Requiring Percutaneous Coronary Intervention after Coronary Artery Bypass Grafting in a Patient with Moyamoya Disease

  • Kim, Hyeon A;Kim, Young Su;Kim, Wook Sung
    • Journal of Chest Surgery
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    • v.54 no.2
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    • pp.150-153
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    • 2021
  • Moyamoya disease (MMD) is characterized by progressive steno-occlusive lesions of the distal or proximal branch of the internal carotid arteries, and cerebrovascular symptoms are its major complications. Extracranial vascular involvement including the coronary artery has been reported, and some case reports have described variant angina or myocardial infarction. However, no report has yet described a case of myocardial infarction after coronary artery bypass grafting (CABG). Here, we present a patient with MMD who suffered cardiac arrest caused by myocardial infarction due to a coronary spasm after offpump CABG and who was discharged successfully after treatment with a veno-arterial extracorporeal membrane oxygenator and percutaneous coronary intervention.

Surgical Treatment of an Aneurysmal Coronary Artery Fistula between the Left Coronary Artery and Right Atrium: A Case Report

  • Jae Hoon Kim;Jae Suk Yoo
    • Journal of Chest Surgery
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    • v.57 no.2
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    • pp.220-224
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    • 2024
  • A coronary artery fistula (CAF) is an abnormal vascular connection between the coronary arteries and the cardiac chambers or major vessels. Although rare, CAFs can lead to substantial coronary morbidity and mortality. This study outlines the surgical management of a CAF originating from the left coronary artery and connecting to the right atrium, in a patient experiencing angina with a marked left-to-right shunt. The surgical approach involved ligation of the coronary artery and reduction of the aneurysmal portion, resulting in the patient's uneventful recovery.

Anatomically Corrected Malposition of the Great Arteries One Case Report (Anatomically Corrected Malposition of the Great Arteries 1례 보고)

  • 정덕용
    • Journal of Chest Surgery
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    • v.18 no.4
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    • pp.557-562
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    • 1985
  • One case of anatomically corrected malposition of the great arteries was managed at department of cardiothoracic surgery, Chungnam National University Hospital at May, 1984. Anatomically corrected malposition of the great arteries was an extremely rare congenital heart disease. Only 21 cases were reported in English literatures. If there are no associated cardiac disease, the patient will have normal life span. This 39 year old man had suffered from exertional dyspnea for 6 years. He had carried out normal military service as a sergeant for 8 years, and his life was not restricted before this episode. He had operated under diagnosis of mitral stenoinsufficiency & tricuspid regurgitation but died because of lower cardiac output.,br> At autopsy, the great arteries were malpositioned but viscera and lung were normal position and picture. The aortic valve was located left and anterior to the pulmonic valve and there are bilateral conus in this anatomically corrected malposition of the great arteries. The coronary arteries were normal distribution.

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Coronary Artery Fistula, associated with Patent Ductus Arteriosus (동맥관개존증을 동반한 관상동맥루 1례 치험)

  • 김기봉
    • Journal of Chest Surgery
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    • v.20 no.4
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    • pp.793-797
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    • 1987
  • Coronary artery fistula is an uncommon congenital heart defect that is readily amenable to surgical treatment. This fistula usually originates from the right coronary artery, but may arise from the left coronary artery, both coronary arteries, or single coronary artery. And the fistulous communication is most often to right ventricle, right atrium or pulmonary artery. Recently we experienced one case of congenital coronary artery fistula which was associated with patent ductus arteriosus. The fistulous communication, forming aneurysmal dilatation, was noted between the left anterior descending coronary artery and the right ventricular outflow tract. Cardiopulmonary bypass was employed in this case. After an arteriotomy was made on the aneurysmal coronary artery, both the proximal opening and the termination site of the fistulous tract were directly closed with partial aneurysmorrhaphy. The right ventricular chamber was also opened to evaluate the fistulous termination site. Postoperative hospital course of the patient was uneventful and she was discharged without problems.

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Comparison of Polar Maps of Dipyridamole Stress/Rest MIBI Myocardial SPECT and Coronary Angiography in Coronary Artery Disease (관동맥질환에서 디피리다몰부하 $^{99m}Tc$-MIBI 심근 SPECT 극성지도와 관동맥 조영소견의 비교)

  • Lee, Myung-Chul;Lee, Dong-Soo;Lee, Myung-Yong;Choi, Chang-Woon;Sohn, Dae-Won;Chung, June-Key;Lee, Myong-Mook;Park, Young-Bae;Seo, Jung-Don;Lee, Young-Woo;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.27 no.1
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    • pp.51-58
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    • 1993
  • We have anlayzed the polar maps of dipyridamole stress/rest $^{99m}Tc$-MIBI SPECT and compared the quantitated perfusion defects of dipyridamole stress polar map and the findings of coronary angiography in 56 pateints with coronary artery diseases. We performed the same day dipyridamole stress-rest myocardial SPECT, reconstructed the polar maps according to Cedars-Sinai method and quantitated perfusion detects of total myocardium and the territory of each artery, comparing the polar maps of patients with normal files. Stenosis more than 50 percent was considered significant and myocardial ischemic score was calculated as summed score of percents of main coronary arteries. Positive concordance of myocardial SPECT with coronary angiography were 82.6% with left anterior descending artery (LAD), 85.7% with left circumflex artery (LCx) and 78.6% with right coronary artery (RCA). Perfusion defect of SPECT polar map and the stenosis of coronary artery showed the contingency phi of 0.55 (p<0.0001) with total atreries, 0.38 (p = 0.016) with LAD, 0.50 (p<0.0001) with LCx and 0.40 (p = 0.007) with RCA. Dipyridamole stress percent defect of polar map was correlated with myocardial ischemic score with Spearman's rho of 0.47 (p = 0.001) in total arteries, 0.48 (p=0.001) in LAD, 0.56 (p < 0.001) in LCx and 0.38 (p=0.002) in RCA. These findings revealed that defect of the dipyridamole stress myocardial $^{99m}Tc$-MIBI SPECT and the percent extent of this defect were related with significant artery stenosis of individual arteries and the degree of stenosis. We thought that we could use the defects in the polar map of dipyridamole stress $^{99m}Tc$-MIBI SPECT for the quantification of myocardiasl perfusion decrease.

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Analysis of Bypass Grafting Effects in Stenosed Coronary Arteries (협착이 발생된 관상동맥에 대한 이식우회로술의 효과분석)

  • Kim, Hyoung-Ho;Suh, Sang-Ho;Lee, Jeong-Sang
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.2
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    • pp.153-159
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    • 2012
  • Bypass anastomosis is frequently adopted for surgical treatments of stenosed coronary arteries. Optimal coronary bypass grafting should be investigated to improve the patency in arterial bypass techniques. The objective of this study is to analyze the effects of Y-grafting bypasses and T-grafting bypasses for various bifurcation and anastomotic angles. In order to find the optimal geometric configuration, the hemodynamic characteristics are obtained and compared with each other for different geometries. We found that both the left anterior descending artery (LAD) and left circumflex artery (LCX) blood flows were distributed evenly when the bypass grafting angle and bifurcated angle were $30^{\circ}$ and $15^{\circ}$, respectively,.