• International Journal of Computer Science & Network Security
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• 제21권1호
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• pp.192-200
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• 2021

In the mid of the December 2019, the virus has been started to spread from China namely Corona virus. It causes fatalities globally and WHO has been declared as pandemic in the whole world. There are different methods which can fit such types of values which obtain peak and get flattened by the time. The main aim of the paper is to find the best or nearly appropriate modeling of such data. The three different models has been deployed for the fitting of the data of Coronavirus confirmed patients in Pakistan till the date of 20^th November 2020. In this paper, we have conducted analysis based on data obtained from National Institute of Health (NIH) Islamabad and produced a forecast of COVID-19 confirmed cases as well as the number of deaths and recoveries in Pakistan using the Logistic model, Gompertz model and Auto-Regressive Integrated Moving Average Model (ARIMA) model. The fitted models revealed high exponential growth in the number of confirmed cases, deaths and recoveries in Pakistan.

• 수면정신생리
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• 제29권2호
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• pp.29-34
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• 2022

Coronavirus disease 2019 (COVID-19), which was a global pandemic caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), is still a serious public health problem. COVID-19 causes various symptoms not only in the respiratory system but also in various parts of the body and has a significant effect on sleep. Insomnia and poor sleep quality were observed at high rates in patients with COVID-19 as well as in the uninfected general population. Obstructive sleep apnea is also considered a risk factor in patients with severe COVID-19. Virus-induced central nervous system damage is likely to be the cause of many sleep disorders in COVID-19, but psychosocial influences also seem to have played a significant role. Sleep problems persisted at high rates for a considerable period after the infection phase was over. More attention and research on the effect of COVID-19 on sleep is needed in the future.

• Journal of Yeungnam Medical Science
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• 제30권2호
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• pp.95-100
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• 2013

Background: This study was performed to investigate the epidemiologic and clinical features of acute respiratory viral infection in hospitalized children. Methods: From 2010 to 2012, we tested nasopharyngeal swab specimen in 1,584 hospitalized children with multiple real-time polymerase chain reactions to identify 10 kinds of respiratory viruses (including influenza virus A, B (FluA, FluB), respiratory syncytial virus (RSV), human metapneumovirus (MPV), adenovirus (AdV), human coronavirus (CoronaV), human enterovirus (HEV), human bocavirus (HBoV), parainfluenza virus (PIV), and human rhinovirus (Rhinovirus)). We analyzed the positive rate, annual and seasonal variations, and clinical features (respiratory tract and non-respiratory tract) according to the retrospective review of medical records. Results: Respiratory viruses were detected from 678 (42.8%) of 1,584 patients. The most common detected virus was RSV (35.0%), and then AdV (19.0%), HEV (18.1%). The critical period of the respiratory viral infection was during the first 12 months of a child's life. PIV increased by 8.4%, 12.1%, and 21.1% annually. Bronchiolitis was most frequently caused by RSV, and croup was frequently caused by PIV. The most common cause of meningitis was HEV. Hepatitis-associated respiratory virus was developed 111 in 678 cases. Conclusion: Although this study was confined to a single medical center for three years, we identified the epidemiology and clinical feature of respiratory viruses in Daegu from 2010 to 2012. Future surveillance will be necessary for annual and seasonal variations.

• 대기
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• 제32권1호
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• pp.51-60
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• 2022

Corona Virus Disease 19 pandemic (COVID-19) causes many deaths worldwide, and has enormous impacts on society and economy. The COVID-19 was caused by a new type of coronavirus (Severe Acute Respiratory Syndrome Cornonavirus 2; SARS-CoV-2), which has been found that these viruses can be effectively inactivated by ultraviolet (UV) radiation of 290~315 nm. In this study, 90% inactivation time of the SARS-CoV-2 virus was analyzed using ground observation data from Brewer spectrophotometer at Yonsei University, Seoul and simulation data from UVSPEC for the period of 2015~2017 and 2020. Based on 12:00-13:00 noon time, the shortest virus inactivation time were estimated as 13.5 minutes in June and 4.8 minutes in July/August, respectively, under all sky and clear sky conditions. In the diurnal and seasonal variations, SARS-CoV-2 could be inactivated by 90% when exposed to UV radiation within 60 minutes from 10:00 to 14:00, for the period of spring to autumn. However, in winter season, the natural prevention effect was meaningless because the intensity of UV radiation weakened, and the time required for virus inactivation increased. The spread of infectious diseases such as COVID-19 is related to various and complex interactions of several variables, but the natural inactivation of viruses by UV radiation presented in this study, especially seasonal differences, need to be considered as major variables.

• 한국동물위생학회지
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• 제40권2호
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• pp.143-147
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• 2017

A Korean domestic short hair (1-year-old, male) presented with 2 to 3 weeks of seizures, aggressive behavior, vomiting, anorexia, and lethargy. The frequency of seizure had gradually increased from once a week to once every 3 hours. Physical and neurologic examination, diagnostic screening tests, including complete blood count (CBC), serum chemistry, electrolyte, coagulation test, X-ray, ultrasonography, and urinalysis were performed. Feline Leukemia Virus (FeLV), Feline Immunodeficiency Virus (FIV) and Toxoplasma spp. All tested negative, but the Feline Corona Virus (FCoV) kit revealed a positive result. To determine the exact diagnosis, magnetic resonance imaging (MRI) was performed but yielded no specific findings. The patient was then diagnosed with idiopathic epilepsy and treatment of phenobarbital was initiated. A month's treatment with phenobarbital proved ineffective as symptoms worsened. Zonisamide was then selected as an additional anticonvulsant. After adding zonisamide, symptoms improved, and seizures abated for 15 months. This is the first case report in South Korea describing the use of phenobarbital and zonisamide in the treatment of a cat with idiopathic epilepsy.

• 디지털융복합연구
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• 제18권6호
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• pp.479-493
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• 2020

중국 우한 시에서 최초로 발병한 코로나바이러스감염증(이하 COVID-19)으로 인한 인명 피해 및 사회·경제적 손실은 매우 크며 현재 세계 주요 각국에서는 COVID-19와 같은 감염병의 확산을 막기 위해서는 발생 추이를 초기에 정확히 예측하는 것이 중요하다고 보고 감염병 대응 체계 구축 시 인공지능을 적극 활용하고 있다. 이에 본 연구에서는 감염병 확산에 대응하기 위한 해외 각국의 인공지능 활용 현황을 파악, 국내 현황과 비교·분석했으며 몇 가지 시사점을 도출할 수 있었다. 연구 결과 보다 효율적으로 인공지능을 활용해 감염병에 대응하기 위해서는 원 헬스(One Health) 기반의 국가 컨트롤타워 구축이 필요하다는 결론이 도출되었으며 이에 컨트롤타워가 갖춰야 할 요건을 살펴보았다. 또한 국가 안보 차원에서의 감염병 대응을 위해 상위 기관인 의료 빅데이터 거버넌스를 설립할 것을 제안하였다. 향후 본 연구에서 도출된 결론 및 시사점을 정책적으로 활용하기 위한 연구가 필요할 것으로 보이며 본 연구가 제안하는 바를 반영해 제도적 미비점을 보완한다면 감염병 확산 방지 및 의료 빅데이터를 유용하게 활용하는데 긍정적으로 작용할 것으로 전망된다.

• 생명과학회지
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• 제31권6호
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• pp.581-586
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• 2021

COVID-19 (Corona Virus Disease 2019) 감염증에 의한 주요 사망원인은 급성폐렴과 신체 전체에 나타나는 혈전증이며, 증가된 면역반응에 의한 사이토카인 폭풍(cytokine storm)은 고염증 상태와 함께 비정상적인 혈전생성을 더욱 활성화시키는 것으로 알려져 있다. 최근 혈전 생성을 억제하는 low molecular weight heparins의 사용이 사망률을 감소시키며, 대마 추출물이 COVID-19 증상의 완화 및 치료에 효과적임이 보고되었다. 본 연구에서는 대마 성분이 항혈전 활성에 기여하는지를 확인하고자, 대마 잎, 줄기, 뿌리, 미성숙 꽃 및 종실 추출물을 각각 조제하고 이를 대상으로 혈전 생성 억제활성을 평가한 결과, 모든 부위 추출물에서 우수한 항혈전 활성을 확인하였으며, 특히 대마 꽃 추출물에서 강력한 혈액응고인자 저해에 의한 혈전 생성 억제활성을 확인하였다. 그러나 대마꽃 추출물은 적혈구 용혈활성도 강력하여 향후 항혈전 활성물질의 분리가 필요하였다. 본 연구는 대마 부위별 추출물의 항응고 활성에 대한 최초 보고이며, 향후 국내에서 연구 및 사용이 제한된 대마를 이용한 고부가가치 생물소재 개발이 필요함을 제시하고 있다.

• 동의생리병리학회지
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• 제34권6호
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• pp.309-318
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• 2020

Besides respiratory infection, COVID-19 has many neurological symptoms not only loss of smell and taste but also fatigue and brain fog. But it is a challenge to treat the neurological symptoms especially of anosmia and ageusia. In order to search for the therapeutic methods, the geographical diversity and pathological mechanisms of the COVID-19 and two symptoms were investigated from the latest clinical studies. Because the environmental conditions of the monsoon climate zone of East Asia and the Mediterranean and Oceanic climate zone of Italy, Britain, United States and tropical Brazil are different, each of diverse etiology and internal milieu should be considered differently in the treatment. SARS-CoV-2 exhibits the dampness-like characteristics and the olfactory and gustatory disorders are particularly more common than other flu or cold. and it tends to show features of damaging the lung qi of olfaction and heart-spleen qi of gustation. The mechanisms of olfactory and gustatory loss are various according to precursory, inflammatory, non-inflammatory and sequelar forms, so the therapeutic method should be designed for each period and pathology. If the process of inflammation arises from nasal and respiratory, olfactory epithelium to the central nervous structure by way of blood brain barrier, the treatment should be corresponded with the stage and depth of pathogen place. And if the olfactory loss is asymptomatic or in the initial stage, it can be applied intranasal topical scent therapy to relieve temporary locking of qi movement, but maybe also used in parallel together with herbs of relieving dampness toxin latent in the lung parenchyma.

• 한국입자에어로졸학회지
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• 제18권1호
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• pp.1-8
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• 2022

Since 2019, the corona virus has been continuously affect human life. In particular, in the indoor space where people live, infection by airborne transmission of viruses is a problem. Among them, the spread in the subway, which is the main mode of transport for humans, can be serious. To solve this problem, our research team developed an ionic wind collector to collect and remove corona virus using an ionic wind collector and ozone. In order to apply the ionic wind collector to the subway, it must operate in two modes. Because large amounts of ozone are harmful to the human body. There is a mode that collects bio-aerosol from the air using ionic wind and a mode that inactivates viruses floating in the air by generating a large amount of ozone. As the applied voltage increased, the cleaning ability of the ionic wind collector increased, and the farther the distance between the discharge electrode and the ground plate, the higher the cleaning ability even at low current. In addition, clean air delivery rate (CADR) of an ionic wind collector was up to 5.5 m³/min. As a result of measuring the amount of ozone generated, it was confirmed that 50 ppb to 250 ppb was generated, and it was confirmed that ozone generation was controllable in the ionic wind dust collector.

• 통합자연과학논문집
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• 제14권1호
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• pp.11-20
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• 2021

2019년 11월 17일, 중국 우한에서 당시 우한 바이러스라는 이름으로 한 폐렴 증상이 나타나는 감염병이 발발했다. 코로나19 (COVID-19)로 공식 명명됐으며 해당 바이러스가 전 세계 곳곳으로 퍼지면서 세계보건기구(WHO)는 감염병 최고 경고 등급인 "팬데믹(Pandemic)"을 선언을 하였다. 코로나19는 대한민국 역시도 큰 혼란에 빠뜨렸다. 이는 큰 감염자들을 낳았는데, 2020년 1월 20일에 첫 확진자가 발생했으며 여러 번의 파동을 겪으면서 감염자가 꾸준히 증가 중이고, 해가 지난 2021년도 역시 많은 코로나 확진자가 발생 중이다. 전 세계가 팬데믹 상황에 접어들면서 사람과 사람 사이에, 기업과 기업 사이에, 나라와 나라 사이에 벽이 생기면서 인간관계, 국내사업 및 산업, 해외산업까지 모든 성장이 멈추거나 하락하는 추세에 들어서면서 전반적인 사회가 많은 침체를 겪는 중이다. 이 중 우리나라의 모든 성장의 기본이 되는 중소기업과 사회에 진입하여 국가 발전에 이바지하려 하는 청년들은 구인 구직활동에 애를 먹고 있다. 코로나가 발생하기 전에도 구인·구직의 어려움이나 중소기업의 전망은 크게 좋지 못했다. 이런 상황에 코로나까지 발생하여 국가의 전반적인 경제상황이 좋지 않으니, 중소기업의 활력도 많이 감소하고, 전망도 좋지 않아 일자리도 줄여가고, 신입사원 채용도 꺼려하여 많은 어려움이 있다. 본 연구에서는 2019년을 코로나 시대 이전, 2020년을 코로나 시대 이후로 두고 코로나 시대 이전과 이후의 중소기업과 전반적 구인·구직 활동에 대해 평균 차이분석을 통해 비교해보고, 상관분석을 통해 영향을 미치고 있는지에 대해 분석한다. 이를 통해 중소기업의 전망을 우선적으로 높인 이후 기업과 정부의 정책을 통해 구인 구직을 늘리는 방향을 제시한다.