• Title/Summary/Keyword: Cornea

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The use of Lycii Fructus and Chrysanthemum Indicum in the Ophthalmology disease from literature and experimental studies review (문헌 연구와 실험 연구의 분석을 통한 구기자와 감국의 안과질환에 대한 활용)

  • Kim, Bong-Hyun;Park, Jung-Gun;Kang, Se Hyun;Kang, Dong-Won;Nam, Hae Jeong
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.2
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    • pp.1-10
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    • 2018
  • Objectives : To present rough guide for the proper use of Lycii Fructus and Chrysanthemum indicum on ophthalmic patients. Methods : Traditional medical classics(本草綱目, 銀海精微, 秘傳眼科龍木論, 東醫寶鑑) and recent studies for Lycii Fructus and Chrysanthemum indicum were reviewed. Results : The results are as follows. 1. According to traditional medical classics, the efficacy of Lycii Fructus and Chrysanthemum indicum is removing nebula(退?) and improving acuity of vision(明目). 2. According to contemporary studies, Lycii Fructus has strong antioxidant, neuroprotective and anti-inflammatory effect. Chrysanthemum indicum has strong anti-inflammatory effect. Results and Conclusions : The Lycii Fructus is proper to macula or neuro-ophthalmology disease. Chrysanthemum indicum is proper to cornea or conjunctiva disease. Absolutely, It may be changed according to the individual condition. However, this may be a rough guide for usage in Korean medicine ophthalmology.

THE REVIEW OF TRANSMISSION OF INFECTIOUS DISEASE IN HUMAN TISSUE TRANSPLANTATION: PART I ALLOGENIC BONE (동종조직이식술 시 전염성질환의 이환가능성에 대한 고찰 I : 동종골조직)

  • Lee, Eun-Young;Kim, Kyoung-Won;Um, In-Woong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.4
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    • pp.365-370
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    • 2006
  • Viral, bacterial and fungal infections can be transmitted via allografts such as bone, skin, cornea and cardiovascular tissues. Allogenic bone grafts have possibility of transmission of hepatitis C, human immunodeficiency virus (HIV-1), human T-Cell leukaemia virus (HTLV), tuberculosis and other bacterias. The tissue bank should have a policy for obtaining information from the patient's medical report as to whether the donor had risk factors for infectious diseases. Over the past several years, improvements in donor screening criteria, such as excluding potential donor with "high risk" for HIV-1 and hepatitis infection, and donor blood testing result in the reduction of transmission of these diseases. During tissue processing, many allografts are exposed to antibiotics, disinfectants and terminal sterilization such as irradiation, which further reduce or remove the risk of transmitting diseases. Because the effectiveness of some tissue grafts such as, fresh frozen osteochondral grafts, depends on cellular viability, not all can be subjected to sterilization and processing steps and, therefore, the risk of transmission of infectious disease remains. This article is review of the transmission of considering infectious disease in allogenic bone transplantation and the processing steps of reducing the risk. The risk of viral transmission in allografts can be reduced in several standards. The most important are donor-screening tests and the removal of blood and soft tissues by processing steps under the aseptic environment. In conclusion, final sterilizations including the irradiation, can be establish the safety of allografts.

A Convergence Study on Wearing Contact Lenses after Corneal Refractive Surgery (각막굴절수술 후 콘택트렌즈 착용에 대한 융복합적 연구)

  • Park, Hye-Won
    • Journal of the Korea Convergence Society
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    • v.9 no.8
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    • pp.117-125
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    • 2018
  • Aims of this study was to investigate on the actual condition of contact lens wearing after corneal refractive surgery, base curves and diameters of lenses on sale, and to confirm movement of lens and wear patterns when wearing of lenses in the modified cornea. After surgery, 16.5% of the respondents had experience wearing contact lenses. Also, the mostly distributed contact lenses had B.C. 8.6mm and DIA.14.0mm. The corneas of 24 eye after corneal refractive surgery were flat, the lenses moved towards inferior and temporal when wearing the lens. After corneal refractive surgery, contact lens wear may feel uncomfortable may require the detailed description and sophisticated fitting due to the limited type of contact lens. It is thought that convergence will be necessary in the industry and clinical study of contact lenses.

Early Onset of Minimal change Nephrotic Syndrome during Treatment with D-penicillamine in a Patient with Wilson's Disease (월슨병 환아에서 D-penicillamine 사용 중 조기 발병한 미세변화형 신증후군 1례)

  • Kim Ki-Soo;Lim Jae-Woo;Ko Kyong-Og;Kim Yoon-Mee;Cheon Eun-Jung
    • Childhood Kidney Diseases
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    • v.8 no.2
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    • pp.250-255
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    • 2004
  • Wilson's disease is an autosomal recessive disorder characterized by degenerative changes in the brain, liver, and cornea. Treatment includes D-penicillamine, trientine, and zinc sulfate. D-penicillamine has been used frequently as first line therapy for Wilson's disease. However, nephrotoxicity can occur after D-penlcillamlne treatment. Among them membranous glomerulopathy is the most common histological abnormality but minimal change lesions have also been reported. Nephrotic syndrome is a late complication of D-penicillamine treatment but very rarely can occur within 2 months after treatment of D-penicillamine. We report the early development of minimal change nephrotic syn,frome in a 3-year-old'girl with Wilson's disease 3 weeks after initiation of D-penicillamine.

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Damped Oscill ations of the (Hard)Contact Lenses Posterior to the Blink (순목 후 콘택트(하드)렌즈의 감쇄 진동)

  • Kim, Dae-Soo
    • Journal of Korean Ophthalmic Optics Society
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    • v.10 no.3
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    • pp.173-184
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    • 2005
  • A capillary action-induced tension develops in the tear layer between the contact lens and cornea, which leads to the restoring force due to difference in the layer thickness between either upper and lower or left and right side of the lens when it is displaced off the equilibrium position as a result of blinking. Suppose the lens was displaced a certain distance from the equilibrium position, lens starts to oscillate toward the equilibrium position with the decreasing amplitude due to the restoring force as well as the velocity dependent viscous damping force in the tear layer. A mathematical model which consists of the differential equations and their numerical solution was proposed to analyze the damped oscillations of lenses. The model predicts the time dependence of lenses after the blink varying the various parameters such as Be, diameters, masses and positions displaced from equilibrium. As the Be and mass of lens increases the rate of amplitude reduction decreases, which requires a more time for the lens to return to the equilibrium position. It seems that varying the lens' displacement and diameters affect the lens' motion very little.

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Seaweed Community of the Subtidal Rocky Habitats along the Coast of Geumo Archipelago in the Central South Sea of Korea (한국 남해중부 금오열도 연안 암반 조하대 해조군집의 구조)

  • Kang, Rae-Seon;Kim, Jong-Man
    • ALGAE
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    • v.19 no.4
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    • pp.339-347
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    • 2004
  • Seaweed community of the sub tidal rocky habitats along the coast of Geumo Archipelago in the central South Sea of Korea is described. This area is characterized by archipelago in which islets are separated by shallow bottom sediments (primary, muddy sand), and turbidity is generally high due to the resuspension of bottom sediments. The hard substrata available for algal attachment are limited to less than 10 m in depth. Thirty sites were randomly chosen along the coast from August 2003 to September 2003 and a 50 m long transect was established at each site. The transect began at a depth of 1 m and ended at the depth of 9 m. The percent cover of all species other than crustose coralline algae was estimated at 2 m depth intervals along the transect using a 0.25 m$^2$ PVC quadrat with 25 squares. Thirty-six species were identified including 6 Chlorophyta, 10 Phaeophyta and 20 Rhodophyta. Species with more than 5% mean bottom cover were Gelidium amansii, Corallina pilulifera, Amphiroa dilatata and Carpopeltis cornea, which formed dense turf-forming algal assemblages at 1-5 m depth. At all sites except S11-S15 located in the western coast of Sorido, bottom covers of seaweed species at the depth deeper than 7 m were less than 6%. The lower limit of algal assemblages was 9 m in depth. We speculate that the limited water clarity and vertical extent of hard substrata available for the settlement of seaweed species are the direct cause of reducing the diversity, abundance and distributional extent of algal assemblages in the area.

Elastic Behavior of Contact Lense(I) : Effect of Vibration (콘택트 렌즈의 탄성에 관한 연구(I) : 진동에 의한 영향)

  • Kim, Dase-Soo
    • Journal of Korean Ophthalmic Optics Society
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    • v.4 no.2
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    • pp.1-16
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    • 1999
  • Differential equations and its numerical solution program using Turbo-C were formulated to describe the radical distribution and average displacement amplitude of vibrating dehydrated contact lens(HEMA) driven by sinusoidal or rectangular pressure. The natural resonant frequency of the lens diaphram(thickness 0.08mm, diameter 14mm, curvature radius 8mm) was measured to be 5730 Hz from the extrapolation of frequency vs addedmass to the diaphram curve. The Young's modulus of the lens was measured to be $4{\times}10^9$ Pa with altering the original shape. The effect of parameters such as thickness, effective radius, damping coeff., amplitude of driving pressure on the vibration characteristics was illustrated by the computer simulation of the derived program. When the frequency of driving pressure coincides with the integral multiple of fundamental resonance frequency of the lens the wave pattern changes from arc to bell-shape along the radial position of the diaphram. If this happens to the contact lens on the cornea in vivo, it might create the feel of pull of the lens due to the increased rise of central part of the lens.

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Anatomical and physiological changes in the aging eye (노인성 변화에 따른 안구와 해부생리학적 고찰)

  • Kim, Jai-Min;Seong, Jeong-Sub;Seo, Eun-Sun;Kho, Eun-Kyung;Lee, Seok-Ju;Yoo, Geun-Chang
    • Journal of Korean Ophthalmic Optics Society
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    • v.9 no.1
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    • pp.135-143
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    • 2004
  • The Human body is subject to two patterns of senescence, both of which are represented in the eye and vision. This article discusses the anatomical and physiological changes in anterior and posterior segments which occur with age. The areas covered include the globe, lids, tears, conjunctiva, cornea, sclera, anterior chamber angle, iris, lens, choroid, vitreous and retina. A sample of 219 individuals between the ages of 50 and 79 years was tested with case history, slit lamp examination, palpebral fissure, horizontal visible iris diameter(HVID) and pupil size. The palpebral fissure decreases with age while HVID remains constant in all age classes. This study suggests that an understanding of anatomical and physiological changes which occur with age is helpful to all eye clinicians because the aging process affects all of the ocular tissues.

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Marine Algal Flora and Community Structure in Dokdo, East Sea, Korea (독도의 해조상 및 군집구조)

  • Choi, Chang-Geun;Lee, Hae-Won;Hong, Byung-Kyu
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.5
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    • pp.503-508
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    • 2009
  • We investigated species composition and variation of benthic marine algae between 2003 and 2006 at Dokdo on the East Sea. The total number of benthic algae species identified was 96, which included 15 Chlorophyta, 30 Phaeophyta, 50 Rhodophyta and 1 Spermatophyta species. The representative species in this study were Ulva pertusa, Caulerpa okamurae, Codium adhaerens, C. frgile, Undaria pinnatifida, Ecklonia cava, Eisenia bicyclis, Dictyopteris undulata, Padina arborescens, Sargassum horneri, Hildenbrandtia rubra, Lithophyllum okamurae, Amphiroa dilatata, Corallina officinalis, C. pilulifera, Prionitis cornea, Grateloupia elliptica, Plocamium telgairiae, Chondrus ocellatus, Chondracanthus intermedia, Chondria crassicaulis, Polysiphonia morrowii, Melobesioidean algae and Phyllospadix sp. Wet weight biomass according to various depths ranged between 1,094.8 to $2,595.3\;g\;m^{-2}$ during the study period. Mean biomass at the investigated sites was greater in the 15m depth range than in the 5 and 10m depths. Vertical distribution was characterized by Ulva intestinalis, U. linza, Endarachne binghamiae, Bangia atropurpurea, Gloiopeltis furcata and Chondria crassicaulis at intertidal zone, Amphiroa dilatata, Corallina pilulifera, Gelidium amansii, Eisenia bicyclis and Ecklonia cava at 2m depth, Ecklonia cava, Eisenia bicyclis, Padina arborescens, Undaria pinnatifida and Sargasum horneri at 5m depth, Ecklonia cava, Sargassum horneri and Padina arborescens at 10m depth, Ecklonia cava, Myagropsis myagroides, Padina arborescens and Sargassum horneri at 15m depth. The R/P, C/P and (R+C)/P value were 1.67, 0.50 and 2.17, respectively.

The Effects of Drugs, including Alcohol, on Ocular Health and Contact Lens Wear (약물과 알코올이 눈과 콘택트렌즈에 미치는 영향)

  • Kim, Jae-Min
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.1
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    • pp.73-81
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    • 2000
  • This review on ocular toxicology concentrates on the effects on ocular health and contact lens wear induced by systemically used drugs, including alcohol. Many systemically administered drugs produce ocular adverse effects. Fortunately, relatively few are capable of causing significant, irreversible visual impairment. The visual symptoms of acute intoxication are as follows : Drop in vision/visual acuity, diplopia, poor dark adaptation, increase in time for glare recovery, early cataract, decreased depth perception, blue-yellow or red-green colour defect and visual hallucinations. Blinking pattern, tear production, and discoloration of contact lenses can be affected by some systemic or local ocular medications. The cornea, conjunctiva, or eyelids may react to some systemic medications and to some preservatives used in contact lens solutions. The hydrogel contact lens act as a drug reservoir that emits the drug over time. I discuss management of contact lens-induced infectious and inflammatory conditions.

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