The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
권호 표지
DOI QR코드

DOI QR Code

The use of Lycii Fructus and Chrysanthemum Indicum in the Ophthalmology disease from literature and experimental studies review

문헌 연구와 실험 연구의 분석을 통한 구기자와 감국의 안과질환에 대한 활용

  • Kim, Bong-Hyun (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Park, Jung-Gun (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Se Hyun (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Dong-Won (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Nam, Hae Jeong (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
  • 김봉현 (경희대학교 한의과대학 안이비인후피부과) ;
  • 박중군 (경희대학교 한의과대학 안이비인후피부과) ;
  • 강세현 (경희대학교 한의과대학 안이비인후피부과) ;
  • 강동원 (경희대학교 한의과대학 안이비인후피부과) ;
  • 남혜정 (경희대학교 한의과대학 안이비인후피부과)
  • Received : 2018.04.06
  • Accepted : 2018.05.04
  • Published : 2018.05.25
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : To present rough guide for the proper use of Lycii Fructus and Chrysanthemum indicum on ophthalmic patients. Methods : Traditional medical classics(本草綱目, 銀海精微, 秘傳眼科龍木論, 東醫寶鑑) and recent studies for Lycii Fructus and Chrysanthemum indicum were reviewed. Results : The results are as follows. 1. According to traditional medical classics, the efficacy of Lycii Fructus and Chrysanthemum indicum is removing nebula(退?) and improving acuity of vision(明目). 2. According to contemporary studies, Lycii Fructus has strong antioxidant, neuroprotective and anti-inflammatory effect. Chrysanthemum indicum has strong anti-inflammatory effect. Results and Conclusions : The Lycii Fructus is proper to macula or neuro-ophthalmology disease. Chrysanthemum indicum is proper to cornea or conjunctiva disease. Absolutely, It may be changed according to the individual condition. However, this may be a rough guide for usage in Korean medicine ophthalmology.

Keywords

References

  1. Kim KW. Lectures-Chinese History of Medicine. Goyang:Daesung medical press. 2016.
  2. Li C, Cao J. Chinese Ophthalmology. 4th ed. Beijing:China press of traditional chinese medicine. 2016.
  3. Kim C-Y, Lee D-J, Seo H-S, Kwon K. The Review on the Ophthalmology related articles published in the Journal of Korean Medical Ophthalmology, Otolaryngology, Dermatology. J Korean Med Ophthalmol Otolaryngol Dermatol. 2014;27(2):14-32. https://doi.org/10.6114/jkood.2014.27.2.014
  4. Ahn JH, Jeong H-A. The Analysis on Annual, Seasonal tendency of Outpatients in ophthalmology & Otolaryngology & Dermatology clinic of Korean Medical hospital from 2012 to 2016. J Korean Med Ophthalmol Otolaryngol Dermatol. 2017;30(2):19-37. https://doi.org/10.6114/JKOOD.2017.30.2.019
  5. Bittner AK, Seger K, Salveson R, Kayser S, Morrison N, Vargas P, et al. Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa. Acta Ophthalmol. 2017.
  6. Xu J, Peng Q. Retinitis Pigmentosa Treatment with Western Medicine and Traditional Chinese Medicine Therapies. J Ophthalmol. 2015;2015:421269.
  7. Chang CM, Chu HT, Wei YH, Chen FP, Wang S, Wu PC, et al. The Core Pattern Analysis on Chinese Herbal Medicine for Sjogren's syndrome: A Nationwide Population-Based Study. Sci Rep. 2015;5:9541. https://doi.org/10.1038/srep09541
  8. Ministry of Food and Drug Safety. The Korean Pharmacopoeia Eleventh Edition. Seoul:Yakup news. 2015.
  9. Ministry of Food and Drug Safety. The Korean Herbal Pharmacopoeia. Seoul:Shinil Books. 2016.
  10. Li S. Compendium of Materia Medica. 2nd ed. Beijing:Beijing Yanshan Press. 2010: 1094-99,2567-75.
  11. Heo J. Donguibogam. Seoul:Bubin publishes. 2007:652-6,2005.
  12. Son SM. Eunhaejungmi. Available from: URL:https://mediclassics.kr/books/112
  13. Baoguangdaoren. Michuanyankelongmulun. Beijing Science and Technology Press. 2013:92-104.
  14. Ma DJ, Yu HG. Nutritional supplement for age-related macular degeneration. J Korean Med Assoc. 2016;59(12):955-62. https://doi.org/10.5124/jkma.2016.59.12.955
  15. Pinazo-Duran MD, Gallego-Pinazo R, Garcia-Medina JJ, Zanon-Moreno V, Nucci C, Dolz-Marco R, et al. Oxidative stress and its downstream signaling in aging eyes. Clin Interv Aging. 2014;9:637-52.
  16. Evans JR, Lawrenson JG. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane Database Syst Rev. 2017;7:CD000254.
  17. Bucheli P, Vidal K, Shen L, Gu Z, Zhang C, Miller LE, et al. Goji berry effects on macular characteristics and plasma antioxidant levels. Optom Vis Sci. 2011;88(2):257-62. https://doi.org/10.1097/OPX.0b013e318205a18f
  18. Wang K, Xiao J, Peng B, Xing F, So K-F, Tipoe GL, et al. Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration. Sci Rep. 2014;4:7601.
  19. Liu L, Lao W, Ji Q-S, Yang Z-H, Yu G-C, Zhong J-X. Lycium barbarum polysaccharides protected human retinal pigment epithelial cells against oxidative stress-induced apoptosis. Int J Ophthalmol. 2015;8(1):11-6. https://doi.org/10.17816/OV2015211-27
  20. Xing X, Liu F, Xiao J, So KF. Neuroprotective Mechanisms of Lycium barbarum. NeuroMolecular Med. 2016;18(3):253-63. https://doi.org/10.1007/s12017-016-8393-y
  21. Vander S, Levkovitch-Verbin H. Regulation of cell death and survival pathways in secondary degeneration of the optic nerve - a long-term study. Curr Eye Res. 2012;37(8):740-8. https://doi.org/10.3109/02713683.2012.673679
  22. Li H, Liang Y, Chiu K, Yuan Q, Lin B, Chang RC-C, et al. Lycium barbarum (wolfberry) reduces secondary degeneration and oxidative stress, and inhibits JNK pathway in retina after partial optic nerve transection. PLoS one. 2013;8(7):e68881. https://doi.org/10.1371/journal.pone.0068881
  23. Yu Y, Wu X, Pu J, Luo P, Ma W, Wang J, et al. Lycium barbarum polysaccharide protects against oxygen glucose deprivation/reoxygenation-induced apoptosis and autophagic cell death via the PI3K/Akt/mTOR signaling pathway in primary cultured hippocampal neurons. Biochem Biophys Res Commun. 2018;495(1):1187-94. https://doi.org/10.1016/j.bbrc.2017.11.165
  24. Sirdah MM. Protective and therapeutic effectiveness of taurine in diabetes mellitus: A rationale for antioxidant supplementation. Diabetes Metab Syndr. 2015;9:55-64. https://doi.org/10.1016/j.dsx.2014.05.001
  25. Behl T, Kotwani A. Chinese herbal drugs for the treatment of diabetic retinopathy. J Pharm Pharmacol. 2017;69(3):223-35. https://doi.org/10.1111/jphp.12683
  26. Nardi G, anuario A de F, Freire C, Megiolaro F, Schneider K, Perazzoli MA, et al. Anti-inflammatory activity of berry fruits in mice model of inflammation is based on oxidative stress modulation. Pharmacognosy Res. 2016;8:S42-9. https://doi.org/10.4103/0974-8490.178642
  27. Zhou S-F, Cheng J, Zhou Z-W, Sheng H-P, He L-J, Fan X-W, et al. An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides. Drug Des Devel and Thera. 2014;9:33-78.
  28. Chen Z, Soo MY, Srinivasan N, Tan BKH, Chan SH. Activation of macrophages by polysaccharide-protein complex from Lycium barbarum L. Phytother Res. 2009;23(8):1116-22. https://doi.org/10.1002/ptr.2757
  29. Song MY, Jung HW, Kang SY, Kim K-H, Park Y-K. Anti-Inflammatory Effect of Lycii radicis in LPS-Stimulated RAW 264.7 Macrophages. Am J Chin Med. 2014;42 (4):891-904. https://doi.org/10.1142/S0192415X14500566
  30. Craig JP, Nelson JD, Azar DT, Belmonte C, Bron AJ, Chauhan SK, et al. TFOS DEWS II Report Executive Summary. Ocul surf. 2017;15(4):802-12. https://doi.org/10.1016/j.jtos.2017.08.003
  31. Chien K, Horng C, Huang Y, Hsieh Y, Wang C, Yang J, et al. Effects of Lycium barbarum (goji berry) on dry eye disease in rats. Mol Med Rep. 2018;17(1):809-18.
  32. Wu X-L, Feng X-X, Li C-W, Zhang X-J, Chen Z-W, Chen J-N, et al. The Protective Effects of the Supercritical-Carbon Dioxide Fluid Extract of Chrysanthemum indicum against Lipopolysaccharide-Induced Acute Lung Injury in Mice via Modulating Toll-Like Receptor 4 Signaling Pathway. Mediators Inflamm. 2014;2014:1-13.
  33. Cheon MS, Yoon T, Lee DY, Choi G, Moon BC, Lee A-Y, et al. Chrysanthemum indicum Linneextract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharideinduced RAW 264.7 macrophages. J ethnopharmacol. 2009;122(3):473-7. https://doi.org/10.1016/j.jep.2009.01.034
  34. Dong M, Yu D, Abdullah Al-Dhabi N, Duraipandiyan V. The Impacts of Chrysanthemum indicum Extract on Oxidative Stress and Inflammatory Responses in Adjuvant-Induced Arthritic Rats. Evid Based Complement Alternat Med. 2017;2017:1-7.
  35. Dong M, Yu D, Duraipandiyan V, Abdullah Al-Dhabi N. The Protective Effect of Chrysanthemum indicum Extract against Ankylosing Spondylitis in Mouse Models. BioMed Research International. 2017;2017:1-7.
  36. Constitutional Court of Korea. 2013.12.26. 2012헌마551 등.
  37. Kubo Y, Akanuma S, Hosoya K. Impact of SLC6A Transporters in Physiological Taurine Transport at the Blood-Retinal Barrier and in the Liver. Biol Pharm Bull. 2016;39(12):1903-11. https://doi.org/10.1248/bpb.b16-00597

Cited by

  1. 밀러-피셔 증후군 환자의 양안 외전신경마비 치험 1례 vol.33, pp.4, 2020, https://doi.org/10.6114/jkood.2020.33.4.133