• The Korean Journal of Urological Oncology
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• v.16 no.3
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• pp.110-118
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• 2018

Purpose: The aim of this study is to confirm the detection rate of transperineal biopsy after multiparametric magnetic resonance imaging (mpMRI) and compared it to that of transrectal biopsy. We also examined the role of mpMRI and the rate of complications for each method. Materials and Methods: In a retrospective study, we analyzed 147 patients who underwent mpMRI before prostate biopsy because of elevated serum prostate-specific antigen and/or abnormal digital rectal examination findings at Korea University Hospital, Seoul, Korea from March 2017 to April 2018. Regions on the mpMRI that were suggestive of prostate cancer were categorized according to the Prostate Imaging-Reporting and Data System (PI-RADS v2). For transperineal biopsy, a 20-core saturation biopsy was performed by MRI-TRUS cognitive or fusion techniques and a 12-core biopsy was performed in transrectal biopsy. Results: Sixty-three and 84 patients were enrolled in transperineal group and transrectal group, respectively. The overall detection rate of prostate cancer in transperineal group was 27% higher than that in transrectal group. Classification according to PI-RADS score revealed a significant increase in detection rate in all patients, as the PI-RADS score increased. Frequency of complications using the Clavien-Dindo classifications revealed no significant differences in the total complications rate, but two patients in transrectal group received intensive care unit care due to urosepsis. Conclusions: Our results confirmed that transperineal biopsy is superior to transrectal biopsy for the detection of prostate cancer. From the complication point of view, this study confirmed that there were fewer severe complications in transperineal biopsy.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.80.1-80.1
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• 2017

We present preliminary results of KVN single dish telescope observations of 80 dense cores in the Orion molecular cloud complex which contains the Orion A, B, and ${\lambda}$ Orionis cloud. We investigate the behavior of the different molecular tracers and look for chemical variations of cores in the three clouds in order to systematically investigate the effects of stellar feedback. The most commonly detected molecular lines (with the detection rates higher than 50%) are N2H+, HCO+, H13CO+, C2H, HCN, and H2CO. The detection rates of dense gas tracers, N2H+, HCO+, H13CO+, and C2H show the lowest values in the ${\lambda}$ Orionis cloud. We find difference between molecular D/H ratios and N2H+/H13CO+ abundance ratios towards different clouds, and between protostellar cores and starless cores. Eight starless cores in the Orion A and B clouds exhibit high deuterium fractionations, larger than 0.10, while in the ${\lambda}$ Orionis cloud, no cores reveal the high ratio. These chemical properties could support that cores in the ${\lambda}$ Orionis cloud are affected by the photo-dissociation and external heating from the nearby H II region, which is a hint of negative stellar feedback on core formation. The striking difference between the [N2H+]/[H13CO+] ratios leads us to suggest that there are significant evolutionary differences between the Orion A/B and ${\lambda}$ Orionis clouds. In order to examine whether starless cores can be candidates of pre-stellar cores, we compared the core masses estimated from the 850 um emission to their Virial masses calculated from the N2H+ line data and find that most of them are not gravitationally bound in the three clouds.

• The KIPS Transactions:PartD
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• v.15D no.4
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• pp.557-568
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• 2008

An ontology as the core element of Semantic Web is a formal specification of a conceptualization of shared domain knowledge. The use of well-defined ontologies can increase the quality of interoperable information systems in the area of Semantic Web. However, in practice, it is not easy to develop high-quality ontologies which have no errors. Therefore, with methodologies for ontology design, various methods or tools for ontology analysis supporting for error-detection might be very helpful for ontology developers. In this paper, we propose a novel approach for analyzing the core constructs of ontology based on the Formal Concept Analysis and develop a tool that supports error-checking ontologies. Our approach can serve not only as a guidance to modify the existing ontologies, but also as a valuable tool in developing high-quality ontologies.

• Journal of IKEEE
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• v.21 no.4
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• pp.358-367
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• 2017

Advanced Driver Assistance Systems(ADAS), such as Front Collision Warning System (FCWS) are currently being developed. FCWS require high processing speed because it must operate in real time while driving. In addition, a low-power system is required to operate in an automobile embedded system. In this paper, FCWS is implemented in CPU-FPGA architecture in embedded system to enable real-time processing. The lane detection enabled the use of the Inverse Transform Perspective (IPM) and sliding window methods to operate at fast speed. To detect the vehicle, a Convolutional Neural Network (CNN) with high recognition rate and accelerated by parallel processing in FPGA is used. The proposed architecture was verified using Intel FPGA Cyclone V SoC(System on Chip) with ARM-Core A9 which operates in low power and on-board FPGA. The performance of FCWS in HD resolution is 44FPS, which is real time, and energy efficiency is about 3.33 times higher than that of high performance PC enviroment.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.3
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• pp.499-505
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• 2018

Shipping and logistics safety, security system is strengthening worldwide, the development of shipping and logistics safety security core technology for national security logistics system construction has been carried out. In addition, it is necessary to localize the Array Detection System, which is a core component of the container search machine, to cope with the 100% pre-inspection of the container scheduled for 2018 in the United States. In this research, we propose a test software program developed by using TI-RTOS (Texas Instruments - Real Time Operating System) with a test digital signal processing board which is developed self development. We have developed a program that can test GPIO, SRAM, TCP/IP, and SDcard using M4 MCU. Also we propose a study on a self-developed Digital Signal Processing Board among the array detection systems that replace foreign products. We have developed a test board that can test M4 MCU and developed an X-Ray Detector Digital Signal Processing Board that combines MCU and FPGA.

• Journal of Internet Computing and Services
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• v.11 no.1
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• pp.1-13
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• 2010

It is not easy to set RED(Random Early Detection) parameter according to environment in managing Network Device. Especially, it is more difficult to set parameter in the case of maintaining the constant service rate according to the change of environment. In this paper, we hypothesize the router that has Multi-core CPU in output queue and propose AI RED(Artificial Intelligence RED), which directly induces Genetic Algorithm of Artificial Intelligence in the output queue that is appropriate to the optimization of parameter according to RED environment, which is automatically adaptive to workload. As a result, AI RED Is simpler and finer than FuRED(Fuzzy-Logic-based RED), and RED parameter that AI RED searches through simulations is more adaptive to environment than standard RED parameter, providing the effective service. Consequently, the automation of management of RED parameter can provide a manager with the enhancement of efficiency in Network management.

• Journal of Platform Technology
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• v.11 no.6
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• pp.106-115
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• 2023

In this paper, we propose a sensor data sharing system for the safe and smooth operation of autonomous vehicles on two-way single lanes in traffic-isolated areas and implement the core module, the situational awareness technology. Two-way single lanes pose challenges for autonomous vehicles, particularly when encountering parked vehicles or oncoming traffic, leading to reversing issues. We introduce a system using infrastructure cameras to detect vehicles' approach, enter, and leave on twoway single lanes in real-time, transmitting this information to autonomous vehicles via V2N communication, thereby expanding the sensing range of the autonomous vehicles. The core part of the proposed system is the situational awareness of the two-way single lane using infrastructure cameras. In this paper, we implement this using object detection and tracking technology. Finally, we validate the implemented situational awareness technology using data collected from actual two-way single lanes.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5171-5174
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• 2014

Background: The increase in breast cancer awareness and widespread use of mammographic screening has led to an increased detection of (non-palpable) breast cancers that cannot be discovered through physical examination. One of the methods used in the diagnosis of these cancers is vacuum-assisted core biopsy, which prevents a considerable number of patients from undergoing surgical procedures. The aim of this study was to present the results of stereotactic vacuum-assisted core biopsy for suspicious breast lesions. Materials and Methods: Files were retrospectively scanned and data on demographic, radiological and pathological findings were recorded for patients who underwent stereotactic vacuum-assisted core biopsy due to suspicious mammographic findings at the Interventional Radiology Centre of the Florence Nightingale Hospital between January 2010, and April 2013. Statistical analysis was carried out using Pearson's Chi-square, continuity correction, and Fisher's exact tests. Results: The mean age of the patients was 47 years (range: 36-70). Biopsies were performed due to BIRADS 3 lesions in 8 patients, BIRADS 4 lesions in 77 patients, and BIRADS 5 lesions in 3 patients. Mammography elucidated clusters of microcalcifications in 73 patients (83%) and focal lesions (asymmetrical density, distortion) in 15 patients (17%). In terms of complications, 1 patient had a hematoma, and 2 patients had ecchymoses (3/88; 3.3%). The histopathologic results revealed benign lesions in 63 patients (71.6%) and malignant lesions in 25 patients (28.4%). The mean duration of the procedure was 37 minutes (range: 18-55). Although all of the BIRADS 3 lesions were benign, 22 (28.6%) of the BIRADS 4 lesions and all of the BIRADS 5 lesions were malignant. Among the malignant cases, 80% were in situ, and 20% were invasive carcinomas. These patients underwent surgery. Conclusions: In cases where non-palpable breast lesions are considered to be suspicious in mammography scans, the vacuum-assisted core biopsy method provides an accurate histopathologic diagnosis thus preventing a significant number of patients undergoing unnecessary surgical procedures.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9335-9339
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• 2014

Background: To determine the frequency of primary circulating prostate cells (CPC) detection according to age and serum PSA levels in a cohort of men undergoing screening for prostate cancer and to determine the diagnostic yield in those men complying with the criteria for prostate biopsy. Materials and Methods: A prospective study was carried out to analyze all men evaluated in a hospital prostate cancer screening program. Primary CPCs were obtained by differential gel centrifugation and detected using standard immunocytochemistry using anti-PSA, positive samples undergoing a second process with anti-P504S. A malignant primary CPC was defined as PSA+ P504S+, and a test positive if 1 cell/4ml was detected. The frequency of primary CPC detection was compared with age and serum PSA levels. Men with a PSA >4.0ng/ml and/or abnormal rectal examination underwent 12 core prostate biopsy, and the results were registered as cancer/no-cancer and compared with the presence/absence of primary CPCs to calculate the diagnostic yield. Results: A total of 1,117 men participated; there was an association of primary CPC detection with increasing age and increasing serum PSA. Some 559 men underwent initial prostate biopsy of whom 207/559 (37.0%) were positive for primary CPCs and 183/559 (32.0%) had prostate cancer detected. The diagnostic yield of primary CPCs had a sensitivity of 88.5%, a specificity of 88.0%, and positive and negative predictive values of 78.3% and 94.9%, respectively. Conclusions: The use of primary CPCs for testing is recommended, since its high negative predictive value could be used to avoid prostate biopsy in men with an elevated PSA and/or abnormal DRE. Men positive for primary CPCs should undergo prostate biopsy. It is a test that could be implemented in the routine immunocytochemical laboratory.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3385-3390
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• 2016

Background: Sequential use of circulating prostate cell (CPC) detection has been reported to potentially decrease the number of unnecessary prostate biopsies in men suspected of prostate cancer. In order to determine the real world effectiveness of the test, we present a prospective study of men referred to two hospitals from primary care physicians, one using CPC detection to determine the necessity of prostate biopsy the other not doing so. Materials and Methods: Men with a suspicion of prostate cancer because of elevated PSA >4.0ng/ml or abnormal DRE were referred to Hospitals A or B. In Hospital A all underwent 12 core TRUS biopsy, in Hospital B only men CPC (+), with mononuclear cells obtained by differential gel centrifugation identified using double immunomarking with anti-PSA and anti-P504S, were recommended to undergo TRUS biopsy. Biopsies were classifed as cancer or no-cancer. Diagnostic yields were calculated, including the number of posible biopsies that could be avoided and the number of clinically significant cancers that would be missed. Results: Totals of 649 men attended Hospital A, and 552 men attended Hospital B; there were no significant differences in age or serum PSA levels. In Hospital A, 228 (35.1%) men had prostate cancer detected, CPC detection had a sensitivity of 80.7%, a specificity of 88.6%, and a negative predictive value of 89.5%. Some 39/44 men CPC negative with a positive biopsy had low grade small volume tumors. In Hospital B, 316 (57.2%) underwent biopsy. There were no significant differences between populations in terms of CPC and biopsy results. The reduction in the number of biopsies was 40%. Conclusions: The use of sequential CPC testing in the real world gives a clear decision structure for patient management and can reduce the number of biopsies considerably.