• Title/Summary/Keyword: Core cell

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Co-author network for convergent research pattern analysis in stem cell sector (줄기세포분야 융합연구형태 분석을 위한 공저자 네트워크)

  • Jang, Hae-Lan
    • Journal of the Korea Convergence Society
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    • v.8 no.9
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    • pp.199-209
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    • 2017
  • This study was carried out to confirm a convergent research pattern and researchers' role in stem cell sector by social network analysis. Articles were extracted from 1996 to 2012 in PubMed, 515 authors of 270 embryonic stem cell and induced pluripotent stem cell articles and 1,515 authors of 580 adult stem cell and mesenchymal stem cell articles. Degree(D) and betweenness(B) centrality was measured and co-author network was generated for researcher's role. As a result, Core researcher and Intermediary researcher was identified in co-author network. Core researcher had high D. centrality, otherwise high B. centrality or not. Intermediary researcher for convergent research had high B. centrality and low D. centrality. Conclusively, co-author network will be used as objective data not only to find core researchers in subject area for improving achievement but also to select experts for research project evaluation.

A Generalized Model for Homogenized Reflectors

  • Pogosbekyan, Leonid;Kim, Yeong-Il;Kim, Young-Jin;Joo, Hyung-Kook
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05a
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    • pp.40-45
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    • 1996
  • A new concept of equivalent homogenization is proposed. The concept employs new set of homogenized parameters: homogenized cross sections (XS) and interface matrix (IM), which relates partial currents at the celt interfaces. The idea of interface matrix generalizes the idea of discontinuity factors (DFs), proposed and developed by K.Koebke and K.Smith. The method of K.Smith can be simulated within framework of new method, while the new method approximates heterogeneous cell better in case of the steep flux gradients at the cell interfaces. The attractive shapes of new concept are: improved accuracy, simplicity of incorporation in the existing codes, equal numerical expenses in comparison to the K.Smith's approach. The new concept is useful for: (a) explicit reflector/baffle simulation; (b) control blades simulation; (c) mixed UO2/MOX core simulation, The offered model has been incorporated in the finite difference code and in the nodal code PANBOX. The numerical results show good accuracy of core calculations and insensitivity of homogenized parameters with respect to in- core conditions.

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Analyses of on-the-fly generation of spectral superhomogenization factors for multigroup whole core calculation employing pin-wise slowing-down solutions

  • Seungug Jae;Han Gyu Joo
    • Nuclear Engineering and Technology
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    • v.55 no.3
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    • pp.1084-1096
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    • 2023
  • On-the-fly(OTF) generation of Spectral Superhomogenization(SSPH) factors is analyzed in the multigroup(MG) whole core calculation employing pin-wise continuous energy(CE) slowing-down solutions. The motivation for the work is to avoid the huge computing time required for the generation of a parametrized SSPH factor library(PSSL) which is used to resolve the angular dependency of MG resonance cross sections, and also to exploit the advantage of flexible choice of a MG structure by using CE slowing-down solutions. Two pin-wise CE slowing-down methods, the equivalent Dancoff cell method and the shadowing effect correction method, are evaluated with the OTF SSPH method. The effectiveness of the OTF SSPH method is examined for various simplified and realistic core problems with various MG structures. It is demonstrated that the computing time overhead of this method is negligible whereas the solution accuracy is considerably enhanced.

Development of High Efficiency Gas Turbine/Fuel Cell Hybrid Power Generation System (가스터빈/연료전지 혼합형 고효율 발전시스템 개발)

  • Kim Jae Hwan;Park Poo Min;Yang Soo Seok;Lee Dae Sung
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.06a
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    • pp.243-247
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    • 2005
  • This paper describes an on-going national R&D program for the development of a gas turbine/fuel cell hybrid power generation system and related R&D activities. The final goal of this program is to develop a 200kW-c1ass gas turbine/fuel cell hybrid power generation system and achieve high efficiency over $60\%$ (AC/LHV). In the first phase of the development, a sub-scaled 60kW-class hybrid system based on the 50kW-class microturbine and the 5kW SOFC will be developed for the purpose of concept proof of the hybrid system. Core components such as the microturbine and the SOFC system are being developed and parallel preparation for system integration is being carried out. Before the core components are assembled in the final system. operating characteristics of a hybrid system are investigated from a simulated system where a turbocharger (microturbine simulator) and a modified fuel cell burner test facility (fuel cell simulator) are employed. The 60kW demonstration unit will be built up and operated to provide the valuable information for the preparation of the final full scale 200kW hybrid system.

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The Sex Determination Mechanisms in Maize: Cell Death, Cell Protection and Cell Cycle Arrest (옥수수 성 결정 메커니즘: 세포 사멸, 세포 방어, 세포주기 멈춤)

  • Kim, Jong-Cheol;Lee, Kyun-Oh
    • Journal of Life Science
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    • v.16 no.4
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    • pp.699-703
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    • 2006
  • Maize (Zea mays L.) is a monoecious plant, which separates male (tassel) and female (ear) floret that evolved into increasing heterogeneity. In each floret, male or female, bears both one pistil and three stamens primodia before diverged to unisexual state. When diverged to tassel, pistil cell death occurs in the pistil primodium, which is mediated by TASSELSEED genes. In contrast, cell protection occurs in the ear pistil from TASSELSEED-mediated cell death, which is mediated by SILKLESS1 gene. On the other hand, cell cycle arrest occurred for a long time in the ear stamens and then the stamens eventually dye. The cell cycle regulating genes such as CYCLIN B and WEE1 are involved in this process. Furthermore, the temporal and spatial regulation of gibberellin biosynthesis may cause cell cycle block in arresting stamen cells. This review describes the cell death, cell protection, and cell cycle arrest mechanism during maize sex determination process at the molecular, cellular and developmental biology, and genetic levels.

Molecular Mechanism of Reactive Oxygen Species-dependent ASK1 Activation in Innate Immunity

  • Yamauchi, Shota;Noguchi, Takuya;Ichijo, Hidenori
    • IMMUNE NETWORK
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    • v.8 no.1
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    • pp.1-6
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    • 2008
  • Apoptosis signal-regulating kinase 1 (ASK1), a mitogen- activated protein kinase kinase kinase, plays pivotal roles in stress responses. In addition, ASK1 has emerged as a key regulator of immune responses elicited by pathogen-associated molecular patterns (PAMPs) and endogenous danger signals. Recent studies have demonstrated that reactive oxygen species (ROS)-dependent activation of ASK1 is required for LPS-stimulated cytokine production as well as extracellular ATP-induced apoptosis in immune cells. The mechanism of ROS-dependent regulation of ASK1 activity by thioredoxin and TRAFs has been well characterized. In this review, we focus on the molecular details of the activation of ASK1 and its involvement in innate immunity.

Neutronic study of utilization of discrete thorium-uranium fuel pins in CANDU-6 reactor

  • Deng, Nianbiao;Yu, Tao;Xie, Jinsen;Chen, Zhenping;Xie, Qin;Zhao, Pengcheng;Liu, Zijing;Zeng, Wenjie
    • Nuclear Engineering and Technology
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    • v.51 no.2
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    • pp.377-383
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    • 2019
  • Targeting at simulating the application of thorium-uranium (TU) fuel in the CANDU-6 reactor, this paper analyzes the process using the code DRAGON/DONJON where the discrete TU fuel pins are applied in the CANDU-6 reactor under the time-average equilibrium refueling. The results show that the coolant void reactivity of the assembly analyzed in this paper is lower than that of 37-element bundle cell with natural uranium and 37-element bundle cell with mixed TU fuel pins; that the max time-average channel/bundle power of the core meets the limits - less than 6700kW/860 kW; that the fuel conversion ratio is higher than that of the CANDU-6 reactor with natural uranium; and that the exit burnup increases to 13400 MWd/tU. Thus, the simulation in this paper with the fuel in the 37-element bundle cell using discrete TU fuel pins can be considered to be applied in CANDU-6 reactor with adequate modifications of the core structure and operating modes.

Energy absorption optimization on a sandwich panel with lattice core under the low-velocity impact

  • Keramat Malekzadeh Fard;Meysam Mahmoudi
    • Steel and Composite Structures
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    • v.46 no.4
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    • pp.525-538
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    • 2023
  • This paper focuses on the energy absorption of lattice core sandwich structures of different configurations. The diamond lattice unit cell, which has been extensively investigated for energy absorption applications, is the starting point for this research. The energy absorption behaviour of sandwich structures with an expanded metal sheet as the core is investigated at low-velocity impact loading. Numerical simulations were carried out using ABAQUS/EXPLICIT and the results were thoroughly compared with the experimental results, which indicated desirable accuracy. A parametric analysis, using a Box-Behnken design (BBD), as a method for the design of experiments (DOE), was performed. The samples fabricated in three levels of parameters include 0.081, 0.145, and 0.562 mm2 Cell sizes, and 0, 45, and 90-degree cell orientation, which were investigated. It was observed from experimental data that the angle of cells orientation had the highest degree of influence on the specific energy absorption. The results showed that the angle of cells orientation has been the most influential parameter to increase the peak forces. The results from using the design expert software showed the optimal specific energy absorption and peak force to be 1786 J/kg and 26314.4 N, respectively. The obtained R2 values and normal probability plots indicated a good agreement between the experimental results and those predicted by the model.

Physcial and Fiber Properties of TMP and CTMP from Kenaf Cultivated at Reclaimed Land of Korea

  • Yoon, Seung-Lak;Kojima, Yasuo;Cho, Dong-Ha;Kim, Nam-Hum;Kim, Min-Joong;Lee, Myoung-Ku
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2006.06b
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    • pp.373-379
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    • 2006
  • Fiber characteristics and fiber distribution of thermomechanical pulp(TMP), bisulfite chemithermomechanical pulp(bisulfite CTMP), neutral sulfite chemithermomechanical pulp(neutral sulfite CTMP) from kenaf(Hibiscus cannabinus L., Malvaceae) cultivar Tainug-2 cultivated in the reclaimed land of Korea were examined to use effectively nonwood fibers as an alternative raw material sources for papermaking. Yields of TMP and CTMP from kenaf were lower than those of TMP from hardwoods and CTMP from softwoods and hardwoods. Bark fibers of kenaf cultivar Tainung-2 ranged 2.04 to 2.30 mm long and $18.7{\sim}19.7{\mu}m$ width. Core fibers averaged 0.63 to 0.80 mm long and $29.5{\sim}31.4{\mu}m$ wide. Coarseness of bark fiber was higher than that of core fiber, and fiber from TMP were higher than those from both bisulfite CTMP and neutral sulfite CTMP. Curl indexes of bark fibers were higher than those of core fibers. However curl indexes were not significantly affected by the pulping conditions. Short fiber distributions were higher in core fibers from TMP and CTMP and long fiber distributions were higher in bark fibers. There was no significant difference in fiber distribution of whole and core fibers obtained from TMP and CTMP, Fibers from neutral sulfite CTMP, however, exhibited a little higher long fiber distribution. Distinct difference in anatomical characteristics was found between core and bast fibers of kenaf plant. Parenchyma cell, pith parenchyma cell and vessel were observed in core fibers and bast fiber in bast sections.

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