• BMB Reports
• /
• v.50 no.9
• /
• pp.437-444
• /
• 2017

Different types of eukaryotic cells may adopt seemingly distinct modes of directional cell migration. However, several core aspects are regarded common whether the movement is either ameoboidal or mesenchymal. The region of cells facing the attractive signal is often termed leading edge where lamellipodial structures dominates and the other end of the cell called rear end is often mediating cytoskeletal F-actin contraction involving Myosin-II. Dynamic remodeling of cell-to-matrix adhesion involving integrin is also evident in many types of migrating cells. All these three aspects of cell migration are significantly affected by signaling networks of TorC2, TorC1, and PP2A/B56. Here we review the current views of the mechanistic understanding of these regulatory signaling networks and how these networks affect eukaryotic cell migration.

• 한국가시화정보학회:학술대회논문집
• /
• 2004.11a
• /
• pp.44-47
• /
• 2004

Vortexing might occur during draining from tanks which reduces the rate of outflow. This phenomenon has practical relevance in the fuel feed system in space vehicles and rockets. Due to environmental disturbances rotational motion can be generated in the liquid-propellant tank, which in turn can affect the rate of outflow to the engines. The phenomenon is initialized by rotating the fluid In the experimental tank. The dip quickly develops into a vortex with an air core, which extends to the bottom port, reducing the effective cross-sectional area of the drain outlet and consequently the flow rate. Flow characteristics are investigated using SPIV(Stereoscopic Particle Image Velocimetry) method.

• Smart Structures and Systems
• /
• v.4 no.4
• /
• pp.439-448
• /
• 2008

Optical fiber sensors are by now broadly accepted as an innovative and reliable device for structural health monitoring, to be used either embedded into or bonded on structures. The accuracy of the strain measurement achievable by optical fiber sensors is critically dependent on the characteristics of the bonding of the various interface layers involved in the sensor bonding/embedding (structure material and gluing agent, fiber coating and gluing agent, fiber coating and fiber core). In fact, the signal of the bonded/embedded optical fiber sensor must correspond to the strain experienced by the monitored structure, but the quality of each involved interface can affect the strain transfer. This paper faces the characterization, carried on by both mechanical tests and morphological analysis, of the strain transfer function resulting with epoxidic and vinylester gluing agent on polyimide and acrylate coated optical fibers.

• Proceedings of the KSR Conference
• /
• 2007.11a
• /
• pp.1951-1966
• /
• 2007

This research attempts to examine the effects of import penetration in an industry on the firms' decision of business diversification and provide an integrative framework including the determinants and results of the business diversification. The research results are as follows. First, the import penetration doesn't affect the degree of business diversification. Second, the more profitable their core business industry, the lower the degree of business diversification against the import penetration. In addition, both technology-related assets and marketing-related assets are necessary for business diversification when faced with the import penetration. Finally, the inverted U-shaped relationship is supported between the degree of business diversification and firm performance.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.25 no.4
• /
• pp.54-60
• /
• 2002

In the Supply chain, The ATP(Available to Promise) function doesn't only give customers to conformation of delivery. It can be used by the core function with ATP rule that can reconcile supplies and demands on the supply chain. Therefore We can be acquire the conformation about on the due date of supplier by using the ATP function of management about real and concurrent access on the supply chain, also decide the affect about product availability due to forecasting or customer's orders through the ATP. In this paper, It consolidates the necessity on a ATP and analyzes data which is concerned of ATP. tinder the these environments, defines the ATP nile that can improve the customer value and data flow related the eCRM and builds on a algorithm.

• Korea Journal of Hospital Management
• /
• v.19 no.2
• /
• pp.55-65
• /
• 2014

The objective of this study is to identify the effect of brand evidence on customer satisfaction, and the effect of customer satisfaction on brand verdict in case of hospital management. To achieve this objective, 250 hospital customers were surveyed in Busan and Gyeongnam province. Of these, 220 respondents were used for the analysis. The research results show that brand name, employee service, core service and feelings have a positive effect on customer satisfaction. However, services cape failed to affect customer satisfaction.

• Geomechanics and Engineering
• /
• v.16 no.2
• /
• pp.151-157
• /
• 2018

The constrained conditions of roof and floor for the coal pillar affect the strength of coal pillar very seriously. To analyze the influence of rock mass for the roof and floor on the stability of coal pillar comprehensively, one method based on the mechanical method for the composite rock mass was proposed. In this method, the three rock layers of roof, floor and coal pillar are taken as the bedded composite rock mass. And the influence of rock mass for the roof and floor on the elastic core of coal pillar has been analyzed. This method can obtain not only the derived stress by the cohesive constraining forces for the coal pillar, but also the derived stress for the rock mass of the roof and floor. Moreover, the effect of different mechanical parameters for the roof and floor on the stability of coal pillar have been analyzed systematically. This method can not only analyze the stability of strip coal pillar, but also analyze the stability of other mining pillars whose stress distribution is similar with that of the strip coal pillar.

• Korean Journal of Cognitive Science
• /
• v.18 no.3
• /
• pp.245-254
• /
• 2007

It is an orthodox in epistemology that only those things that affect the truth conduciveness of a belief are relevant to the epistemic rationality of the belief. I criticize this orthodox. In this paper, 1 claim that the epistemic worth of a subject affects the epistemic rationality of inquiries and resulting beliefs. More specifically, I argue that it is epistemically irrational to conduct an inquiry when it is about something unworthy of knowing, and that the epistemic irrationality of an inquiry in this sense makes the resulting beliefs epistemically irrational. After presenting my argument, I defend it from various possible criticisms. Then I explicate the implications of my argument that opposes the core assumptions of contemporary epistemology.

• International Commerce and Information Review
• /
• v.10 no.2
• /
• pp.63-87
• /
• 2008

This study investigates the relationship between perceived system characteristics of Internet shopping mall and loyalty, and examines how perceived website attractiveness and flow play mediating roles between perceived system characteristics of Internet shopping mall and affective commitment in the context of Internet clothing shopping mall. For these purposes, the author developed a structural model which consists of several variables. In this model, perceived system characteristics of Internet shopping mall that consist of such as familiarity, reputation, uniqueness, positive emotion, self-efficacy, and interactivity were proposed to affect the website attractiveness and flow, and in turn, result in higher affective commitment. Thus, perceived website attractiveness and flow were proposed as core mediating variables between perceived mobile service characteristics and affective commitment. To test unidimensionality and nomological validity of the measures of each construct, the author employed scale refinement procedure. The results of reliability test with Cronbach's, and confirmatory factor analysis warranted unidimensionality of the measures for each construct. In addition, nomological validity of the measures was warranted from the result of correlation analysis.

• Journal of ILASS-Korea
• /
• v.6 no.2
• /
• pp.9-15
• /
• 2001

The internal flow characteristics of a gasoline direct injector have been studied to improve fuel economy and reduce exhaust emissions. Computational Fluid Dynamics (CFD) is used to examine the internal flow of the GDI with the purpose of designing the optimum geometry of the injector. This study tests orifice length, cone angle, swirl angle, orifice diameter and needle lift. The results show that optimum sizes of the orifice length, cone angle, swirl angle, orifice diameter and needle lift are 0.8mm, $140^{\circ},\;120^{\circ},\;80mm\;and\;70{\mu}m$, respectively. The size of the lift does not affect the formation of the air core signficantly near the tip of the needle compared to the ball-type needle. The vena contracta phenomenon near the orifice inlet can be released by smoothing the edge.