• Archives of Pharmacal Research
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• v.20 no.5
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• pp.459-464
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• 1997

The human liver cDNA clone UDPGTh2, encoding a liver UDP-glucuronosyltransferase (UDPGT) was isolated from a .gamma. gt 11 cDNA library by hybridization to mouse transferase cDNA clone, UDPGTm1. UDPGTh2 encoded a 529 amino acid protein with an amino terminus membrane-insertion signal peptide and a carboxyl terminus membrane-spanning region. There were three potential asparagine-linked glycosylation sites at residues 67, 68, and 315. In order to obtain UDPGTh2 protein encoded from cloned human liver UDP-glucuronosyltransferase cDNA, the clone was inserted into the pSVL vector (pUDPGTh2) and expressed in COS 1 cells. The presence of a transferase with Mr-52,000 in transfected cells cultured in the presence of $[^{35}S]$ methionine was shown by immunocomplexed products with goat antimouse transferase IgG and protein A-Sepharose and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography. The expressed UDPGT was a glycoprotein as indicated by electrophoretic mobility shift in Mr-3,000-4,000 when expressed in the presence of tunicamycin. The extent of glycosylation was difficult to assess, although one could assume that glycosyl structures incorporated at the level of endoplasmic reticulum were always the core oligosaccharides. Thus, it is likely that at least two moieties inserted can account for the shift of Mr-3,000-4,000. This study demonstrates the cDNA and deduced amino acid sequence of human liver UDP-glucuronosyltransferase cDNA, UDPGTh2.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.23 no.1
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• pp.21-31
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• 2016

Purpose: This study is a qualitative research to identify new nurses' adaptation experience to sleep changes. Method: Grounded theory methodology was utilized. Participants were 10 new nurses from one university hospital. The information was collected and analyzed using the grounded theory of Corbin and Strauss'(2008). Results: Through constant comparative analysis, central phenomenon was identified as 'Shaky daily life due to the sleep change'. A core category emerged as 'In the shaky daily life, go grab my position', Causal conditions were 'Heaviness in shift work', 'Not released after getting off work', and 'Body and mind are exhausted'. Context were 'An environment that does not tolerate mistakes' and 'Clogged breathing due to worries'. Intervening factors were 'Support of colleagues', 'Recovery volition in restoration of altered relationships due to sleep'. Action/Interaction Strategies were 'To strive for a good sleep', 'Require a reasonable duty schedule' and 'Find a breakthrough'. Consequences were 'Become the master of shaky daily life' and 'Accepting the life of a nurse'. Conclusion: New nurses experience sleep patterns changes from the hospital shift system. but throughout the process of adaptation, came to accept sleep disorder as part of the life of a nurse.

• Journal of Intelligence and Information Systems
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• v.21 no.1
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• pp.65-82
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• 2015

Recently, there has been a surge of interest in finding core issues and analyzing emerging trends for the future. This represents efforts to devise national strategies and policies based on the selection of promising areas that can create economic and social added value. The existing studies, including those dedicated to the discovery of future promising fields, have mostly been dependent on qualitative research methods such as literature review and expert judgement. Deriving results from large amounts of information under this approach is both costly and time consuming. Efforts have been made to make up for the weaknesses of the conventional qualitative analysis approach designed to select key promising areas through discovery of future core issues and emerging trend analysis in various areas of academic research. There needs to be a paradigm shift in toward implementing qualitative research methods along with quantitative research methods like text mining in a mutually complementary manner. The change is to ensure objective and practical emerging trend analysis results based on large amounts of data. However, even such studies have had shortcoming related to their dependence on simple keywords for analysis, which makes it difficult to derive meaning from data. Besides, no study has been carried out so far to develop core issues and analyze emerging trends in special domains like the aviation industry. The change used to implement recent studies is being witnessed in various areas such as the steel industry, the information and communications technology industry, the construction industry in architectural engineering and so on. This study focused on retrieving aviation-related core issues and emerging trends from overall research papers pertaining to aviation through text mining, which is one of the big data analysis techniques. In this manner, the promising future areas for the air transport industry are selected based on objective data from aviation-related research papers. In order to compensate for the difficulties in grasping the meaning of single words in emerging trend analysis at keyword levels, this study will adopt topic analysis, which is a technique used to find out general themes latent in text document sets. The analysis will lead to the extraction of topics, which represent keyword sets, thereby discovering core issues and conducting emerging trend analysis. Based on the issues, it identified aviation-related research trends and selected the promising areas for the future. Research on core issue retrieval and emerging trend analysis for the aviation industry based on big data analysis is still in its incipient stages. So, the analysis targets for this study are restricted to data from aviation-related research papers. However, it has significance in that it prepared a quantitative analysis model for continuously monitoring the derived core issues and presenting directions regarding the areas with good prospects for the future. In the future, the scope is slated to expand to cover relevant domestic or international news articles and bidding information as well, thus increasing the reliability of analysis results. On the basis of the topic analysis results, core issues for the aviation industry will be determined. Then, emerging trend analysis for the issues will be implemented by year in order to identify the changes they undergo in time series. Through these procedures, this study aims to prepare a system for developing key promising areas for the future aviation industry as well as for ensuring rapid response. Additionally, the promising areas selected based on the aforementioned results and the analysis of pertinent policy research reports will be compared with the areas in which the actual government investments are made. The results from this comparative analysis are expected to make useful reference materials for future policy development and budget establishment.

• Journal of Electrical Engineering and Technology
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• v.12 no.1
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• pp.173-181
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• 2017

In this paper, the bifurcation criteria for inductive power transfer (IPT) systems is suggested considering the inductive power pad losses. The bifurcation criteria for series-series (SS) and series-parallel (SP) topologies are derived in terms of the main parameters of the IPT system. For deriving precise criteria, power pad resistance is obtained by copper loss calculation and core loss analysis. Utilizing the suggested criteria, possibility of bifurcation occurrence can be predicted in the design process. In order to verify the proposed criteria, 50 W IPT laboratory prototype is fabricated and the feasibilities of the switching frequency and AC load resistance shift to escape from bifurcation are identified.

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05a
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• pp.169-174
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• 1998

An 1200-day time-dependent fuel-management for the transition from 37-element fuel to CANFLEX-NU fuel in a CANDU 6 reactor has been simulated to show the compatibility of the CANFLEX-NU fuel with the reactor operation. The simulation calculation were carried out with the RFSP code, provided by cell averaged hel properties obtained from the POWDERPUFS-V code. The refueling scheme for both fuels was an eight bundle shift art a time. The simulation results show that the maximum channel and bundle powers were maintained below the licence limit of the CANDU 6. This indicates that the CANFLEX-NU fuel bundle is compatible with the CANDU 6 reactor operation during the transition period.

• The Korean Journal of Franchise Management
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• v.3 no.2
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• pp.55-78
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• 2012

The purpose of this study is to devise successful strategies for launching of new brands in franchise companies based on cases of 'Gamarogangjung' of Masedarin Inc. The results of case analysis shaw following successful strategies. First, Masedarin Inc. has used its core competence; Masedarin Inc., which managed chicken franchises for many years, launched the new brand, 'Gamarogangjung' based on its differentiated technologies and infrastructure. Second, the brand, 'Gamarogangjung' has used market oriented strategy actively; the brand has reflected customers' needs to its adminstration immediately by understanding and sharing of customers' needs at the corporate level. Third, Masedarin Inc. has differentiated a business model from other companies; by using 'take out' purchasing system instead of 'delivery to doors' or 'purchasing by visiting', the company has saved huge management cost. Fourth, Masedarin Inc. developed a new kind of business which is differentiated from existing chicken franchise brands or take-out restaurants. Fifth, Masedarin Inc. has appealed its sincerity to franchisees; its business information session, which explains about the business openly without exaggeration, has drawn a high rate of franchise agreement. Sixth, Masedarin Inc. changed its way of thinking about conditions of a location for member stores. The company has selected 'A' level locations for their member stores which enables 'quick sales at small profits' while other take-out stores are usually located at 'B' level location. Lastly, Masedarin Inc. has given thorough instructions to the staff of member stores. And immediately after opening of the stores, franchisees were able to operate the stores comfortably because the company educated the staff repeatedly over a long period to make them master skills before the opening of the store.

• Journal of Adhesion and Interface
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• v.13 no.4
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• pp.188-192
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• 2012

Herein, CdS-coated PMMA nanoparticles were prepared by in-situ surfactant-free emulsion copolymerization and subsequent CdS coating process. As-prepared CdS/PMMA hybrid particles had 201.7 nm in diameter. The amount of CdS nanocrystals in the hybrid particles was 10.37 wt% determined by TGA and elemental analysis. The size of CdS crystals was 3.55 nm preferentially grown in (111) plane. UV-vis spectrum of PMMA/CdS nanoparticles showed the significant blue-shift in optical illumination. The reason was found because the synthesized CdS nanocrystals on PMMA particles had a different band gap energy of 2.70 eV which was significantly higher than that of known-value of bulk CdS (2.41 eV) due to a quantum confinement effect.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.4
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• pp.201-211
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• 2018

The paper suggests making a policy and strategies for a way of exporting Korean ICT product effectively in the EU and Eastern area, and an effective preparation of 4^th industrial revolution through analysis of preparation status of 4^th industrial revolution of the Visegrad group. Analyze policy, status, what they want for 4^th preparation in the Visegrad group from comparing characteristics analysis of each country's official data, publication data, portal, paper, and etc. They have been preparing for 4^th industrial revolution long time ago as basic research and business before 4^th wave word. With these basic results, they are trying to apply such as, AI, S/W, security, ICT, etc. of 4^th wave core technology. For the development of new export market in EU, the Korean team should research with university and research center or venture company. Through these cooperation, they should understand their personal characteristic, lifestyle, and what consumers want to purchase in EU. And this results can be used in South Asia and India that give a big effect to all over the world ICT market. The external impact of the 4^th wave must have a long-term shift in manpower, and production policy is related to the EU's strategic role, or the preparation of the 4^th wave to the V4 country in the short term.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.1
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• pp.506-514
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• 2014

Recently the interest about the vortex intakes are rapidly increased because of its performance to drain a plenty of collected storm water at a time. The tangential intake a kind of vortex intakes is very applicable because this type is very simple and little against other types, but it has a big weakness that the vortex flow is not been rarely created below the design discharge. In this study, the characteristics of a tangential intake and two kinds of a newly suggested compound section type intake are analyzed by the 3D numerical modeling based on theories about the control shift and free drainage condition. The analysis focused on the flow condition, flow surface formation, depth-discharge relation, area ratio of air core. Based on this study, the mild-sloped compound section type intake is the optimal, but steep-sloped compound section type is also the optional for the small design discharge.

• Journal of Microbiology and Biotechnology
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• v.15 no.6
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• pp.1330-1336
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• 2005

Polyhydroxyalkanoic acid (PHA) inclusion bodies were analyzed in situ by $^{13}C$-nuclear magnetic resonance ($^{13}C$-NMR) spectroscopy. The PHA inclusion bodies studied were composed of poly(3-hydroxybutyrate) or poly(3hydroxybutyrate-co-4-hydroxybutyrate), which was accumulated in Hydrogenophaga pseudoflava, and medium-chain-length PHA (MCL-PHA), which was accumulated in Pseudomonas fluorescens BM07 from octanoic acid or 11-phenoxyundecanoic acid (11-POU). The quantification of the $^{13}C$-NMR signals was conducted against a standard compound, sodium 2,2-dimethyl-2-silapentane-5-sulfonate (DSS). The chemical shift values for the in vivo NMR spectral peaks agreed well with those for the corresponding purified PHA polymers. The intracellular degradation of the PHA inclusions by intracellular PHA depolymerase(s) was monitored by in vivo NMR spectroscopy and analyzed in terms of first-order reaction kinetics. The H. pseudoflava cells were washed for the degradation experiment, transferred to a degradation medium without a carbon source, but containing 1.0 g/l ammonium sulfate, and cultivated at $35^{\circ}C$ for 72 h. The in vivo NMR spectra were obtained at $70^{\circ}C$ for the short-chain-length PHA cells whereas the spectra for the aliphatic and aromatic MCL-PHA cells were obtained at $50^{\circ}C\;and\;80^{\circ}C$, respectively. For the H. pseudoflava cells, the in vivo NMR kinetics analysis of the PHA degradation resulted in a first-order degradation rate constant of 0.075/h ($r^{2}$=0.94) for the initial 24 h of degradation, which was close to the 0.050/h determined when using a gas chromatographic analysis of chloroform extracts of sulfuric acid/methanol reaction mixtures of dried whole cells. Accordingly, it is suggested that in vivo $^{13}C$-NMR spectroscopy is an important tool for studying intracellular PHA degradation in terms of kinetics.