• Korean Journal of Social Welfare
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• v.66 no.1
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• pp.221-249
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• 2014

This paper has the objectives to define the concept of 'Good Care' which is the service goal we are aiming essentially for the improvement of long-term care service quality, to find out the components for 'Good Care', and to explore the conditions that create a good care. In addition, we tried to find the answer about what is the best way to measure the service quality. For this, I referred the advanced researches which explored the fundamental properties of care and tried to find the answer from the accumulated wisdom of service field through the 5-year long term care service experience. As a result of research, the good care can be defined as helping someone to be able to maintain his own life as maximum as possible with the goal to assure total quality life. The most important condition for good care is making 'a good care relationship'. Without damaging the relationship between care provider and care receiver, the individualized service focusing on the demand of care receiver based on mutual reliability, mutual respect and smooth communication should be provided. For the evaluation system, it is reasonable to set the standard according to the size of each institution for the core quality of facility service and establish the certification system of absolute standard to carry out the quantitative evaluation rather than the relative evaluation in the whole. For the part over the absolute certification standard, it is reasonable for each institution to characterize its own characteristics autonomously and carry out the qualitative evaluation for this. For the evaluation of home visit care service, it is recommended to contain the evaluation contents such as user satisfaction, satisfaction of care worker, how well the case management system of home care service center is operated etc.

• Nuclear Engineering and Technology
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• v.46 no.4
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• pp.547-556
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• 2014

Korea expects a shortage in storage capacity for spent fuels at reactor sites. Therefore, a need for more metal and/or concrete casks for storage systems is anticipated for either the reactor site or away from the reactor for interim storage. For the purpose of interim storage and transportation, a dual purpose metal cask that can load 21 spent fuel assemblies is being developed by Korea Radioactive Waste Management Corporation (KRMC) in Korea. At first the gamma and neutron flux for the design basis fuel were determined assuming in-core environment (the temperature, pressure, etc. of the moderator, boron, cladding, $UO_2$ pellets) in which the design basis fuel is loaded, as input data. The evaluation simulated burnup up to 45,000 MWD/MTU and decay during ten years of cooling using the SAS2H/OGIGEN-S module of the SCALE5.1 system. The results from the source term evaluation were used as input data for the final shielding evaluation utilizing the MCNP Code, which yielded the effective dose rate. The design of the cask is based on the safety requirements for normal storage conditions under 10 CFR Part 72. A radiation shielding analysis of the metal storage cask optimized for loading 21 design basis fuels was performed for two cases; one for a single cask and the other for a $2{\times}10$ cask array. For the single cask, dose rates at the external surface of the metal cask, 1m and 2m away from the cask surface, were evaluated. For the $2{\times}10$ cask array, dose rates at the center point of the array and at the center of the casks' height were evaluated. The results of the shielding analysis for the single cask show that dose rates were considerably higher at the lower side (from the bottom of the cask to the bottom of the neutron shielding) of the cask, at over 2mSv/hr at the external surface of the cask. However, this is not considered to be a significant issue since additional shielding will be installed at the storage facility. The shielding analysis results for the $2{\times}10$ cask array showed exponential decrease with distance off the sources. The controlled area boundary was calculated to be approximately 280m from the array, with a dose rate of 25mrem/yr. Actual dose rates within the controlled area boundary will be lower than 25mrem/yr, due to the decay of radioactivity of spent fuel in storage.

• The Journal of the Korea Contents Association
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• v.13 no.7
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• pp.238-247
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• 2013

This study aims to examine care workers' role perceptions of their occupation and job satisfaction with their work. They are core human resources in elderly care work practices and their perceptions of their occupation are likely to affect their work performance and job satisfaction. A mail survey is conducted targeting to 400 care workers who are at work in long-term care facilities located in Seoul, Gyeonggi and Pusan. Research findings are as follows: firstly, the perception level of care workers' professionalism is 3.38, and job satisfaction is 3.41. Secondly, the correlation analysis between perception level of professionalism and job satisfaction, coefficient is .553, which shows positive relations between two variables. Thirdly, the study shows that care workers' perceptions of professionalism significantly affects their job satisfaction. This study concludes that it is necessary to take a variety of measures in contribution to improve the quality of service through reinforcement of perception of professionalism higher than present level of care workers who supply direct service in long-term care facilities.

• Journal of the Korean Association of Geographic Information Studies
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• v.10 no.2
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• pp.11-22
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• 2007

This paper is to discuss analytical techniques to estimate demand sizes and volumes that determine optimal locations for multiple facilities for a given services. While demand size estimation is a core part of location modeling to enhance solution quality and practical applicability, the estimation method has been used in limited and restrict parts such as a single population centroid in a given larger census boundary area or small theoretical application experiments(e.s. census track and enumeration district). Therefore, this paper strives to develop an analytical estimation method of demand size that converts area based demand data to point based population weighted centroids. This method is free to spatial boundary units and more robust to estimate accurate demand volumes regardless of geographic boundaries. To improve the estimation accuracy, this paper uses house weighted value to the population centroid calculation process. Then the population weighted centroids are converted to individual demand points on a grid formated surface area. In turn, the population weighted centroids, demand points and network distance measures are operated into location-allocation models to examine their roles to enhance solution quality and applicability of GIS location models. Finally, this paper demonstrates the robustness of the weighted estimation method with the application of location-allocation models.

• Journal of the Society of Disaster Information
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• v.17 no.4
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• pp.684-693
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• 2021

Purpose: The purpose is to establish a safe facility environment from abnormal voltages such as lightning by developing a smart land resistance measuring device that can acquire real-time land resistance data using Arduino. Method: This paper studied design models and application cases by developing a land resistance acquisition and analysis system with Arduino and a power line communication (PLC) system. Some sites in the wind power generation complex in Gyeongsangnam-do were selected as test beds, and real-time land resistance data applied with new technologies were obtained. The electrode arrangement adopted a smart electrode arrangement using a combination of a Wenner four electrode arrangement and a Schlumberger electrode arrangement. Result: First, the characteristic of this technology is that the depth of smart multi-electrodes is organized differently to reduce the error range of the acquired data even in the stratigraphic structure with specificity between floors. Second, IT convergence technology was applied to enable real-time transmission and reception of information on land resistance data acquired from smart ground electrodes through the Internet of Things. Finally, it is possible to establish a regular management system and analyze big data accumulated in the server to check the trend of changes in various elements, and to model the optimal ground algorithm and ground system design for the IT convergence environment. Conclusion: This technology will reduce surge damage caused by lightning on urban infrastructure underlying the 4th industrial era and design an optimized ground system model to protect the safety and life of users. It is also expected to secure intellectual property rights of pure domestic technology to create jobs and revitalize our industry, which has been stagnant as a pandemic in the post-COVID-19 era.

• BMB Reports
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• v.52 no.7
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• pp.463-468
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• 2019

Autosomal dominant polycystic kidney disease (ADPKD), one of the most common human monogenic diseases (frequency of 1/1000-1/400), is characterized by numerous fluid-filled renal cysts (RCs). Inactivation of the PKD1 or PKD2 gene by germline and somatic mutations is necessary for cyst formation in ADPKD. To mechanistically understand cyst formation and growth, we isolated RCs from Korean patients with ADPKD and immortalized them with human telomerase reverse transcriptase (hTERT). Three hTERT-immortalized RC cell lines were characterized as proximal epithelial cells with germline and somatic PKD1 mutations. Thus, we first established hTERT-immortalized proximal cyst cells with somatic PKD1 mutations. Through transcriptome sequencing and Gene Ontology (GO) analysis, we found that upregulated genes were related to cell division and that downregulated genes were related to cell differentiation. We wondered whether the upregulated gene for the chemokine CXCL12 is related to the mTOR signaling pathway in cyst growth in ADPKD. CXCL12 mRNA expression and secretion were increased in RC cell lines. We then examined CXCL12 levels in RC fluids from patients with ADPKD and found increased CXCL12 levels. The CXCL12 receptor CXC chemokine receptor 4 (CXCR4) was upregulated, and the mTOR signaling pathway, which is downstream of the CXCL12/CXCR4 axis, was activated in ADPKD kidney tissue. To confirm activation of the mTOR signaling pathway by CXCL12 via CXCR4, we treated the RC cell lines with recombinant CXCL12 and the CXCR4 antagonist AMD3100; CXCL12 induced the mTOR signaling pathway, but the CXCR4 antagonist AMD3100 blocked the mTOR signaling pathway. Taken together, these results suggest that enhanced CXCL12 in RC fluids activates the mTOR signaling pathway via CXCR4 in ADPKD cyst growth.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.30 no.6
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• pp.467-478
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• 2019

This paper describes the development and measurement results of a wide-band planar active phase array antenna system for an electronic warfare jamming transmitter. The system is designed as an $8{\times}8$ triangular lattice array using a $45^{\circ}$ slant wide-band antenna. The 64-element transmission channel is composed of a wide-band gallium nitride(GaN) solid state power amplifier and a gallium arsenide(GaAs) multi-function core chip(MFC). Each GaAs MFC includes a true-time delay circuit to avoid a wide-band beam squint, a digital attenuator, and a GaAs drive amplifier to electronically steer the transmitted beam over a ${\pm}45^{\circ}$ azimuth angle and ${\pm}25^{\circ}$ elevation angle scan. Measurement of the transmitted beam pattern is conducted using a near-field measurement facility. The EIRP of the designed system, which is 9.8 dB more than the target EIRP performance(P), and the ${\pm}45^{\circ}$ azimuth and ${\pm}25^{\circ}$ elevation beam steering fulfill the desired specifications.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.221-234
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• 2019

Cancer is genetically, metabolically and infectiously induced life threatening disorder showing aggressive growing pattern with invasive tendency. In order to prevent this global menace from jeopardizing human life, enormous studies on carcinogenesis and treatment for chemotherapy resistance have been intensively researched. Hinokitiol (${\beta}$-thujaplicin) extracted from heart wood of cupressaceous is a well-known bioactive compound demonstrating anti-inflammation, anti-bacteria and anti-cancer effects on several cancer types via apoptosis and autophagy. This study proposed that hinokitiol activates transcription factor EB (TFEB) nuclear translocation for autophagy and lysosomal biogenesis regardless of nutrient condition in cancer cells. Mitophagy and ${\beta}$-catenin translocation into the nucleus under treatment of hinokitiol on non-small cell lung cancer (NSCLC) cells and HeLa cells were investigated. Hinokitiol exerted cytotoxicity on HeLa and HCC827 cells; moreover, artificially induced autophagy by overexpression of TFEB granted imperfect sustainability onto HeLa cells. Taken together, hinokitiol is the prominent autophagy inducer and activator of TFEB nuclear translocation. Alternative cancer therapy via autophagy is pros and cons since the autophagy in cancer cells is related to prevention and survival mechanism depending on nutrition. To avoid paradox of autophagy in cancer therapy, fine-tuned regulation and application of hinokitiol in due course for successful suppressing cancer cells are recommended.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.125-133
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• 2019

A microscope is the fundamental research and diagnostic apparatus for clinical investigation of signaling transduction, morphological changes and physiological tracking of cells and intact tissues from patients in the biomedical laboratory science. Proper use, care and maintenance of microscope with comprehensive understanding in mechanism are fully requested for reliable image data and accurate interpretation for diagnosis in the clinical laboratory. The standard operating procedure (SOP) for light microscopes includes performance procedure, brief information of all mechanical parts of microscopes with systematic troubleshooting mechanism depending on the laboratory capacity. Maintenance program encompasses cleaning objective, ocular lenses and inner optics; replacement and calibration of light source; XY sample stage management; point spread function (PSF) measurement for confocal laser scanning microscope (CLSM); quality control (QC) program in fluorescent microscopy; and systematic troubleshooting. Laser safety is one of the concern for medical technologists engaged in CLSM laboratory. Laser safety guideline based on the laser classification and risk level, and advisory lab wear for CLSM users are also expatiated in this overview. Since acquired image data presents a wide range of information at the moment of acquisition, well-maintained microscopes with proper microscopic maintenance program are impulsive for its interpretation and diagnosis in the clinical laboratory.

• Journal of KIBIM
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• v.10 no.1
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• pp.9-22
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• 2020

Recently, BIM has been extended to infrastructures such as roads and bridges, and the demand for BIM standard development for ports is increasing internationally. Due to the low level of utilization of classification system and drawing standards compared to other infrastructures, and the closed nature of national security facilities, ports have insufficient level of connection and sharing environment among external systems or users. In addition, since the standardization of data for port facilities is not made, it is still necessary to establish an independent DB for each system and to ensure interoperability of data between these systems since it does not have a shared environment among similar data. Therefore, the purpose of this study is to develop and verify IFC, the international standard for BIM, in order to cope with the BIM environment and to be commonly used in the design, construction, and maintenance of port facilities. To this end, we build a standard schema with port-specific Express Notation according to buildingSMART International's standard development methodology. First, domestic and international reference model standards were analyzed to derive components such as space and facilities of port facilities. Based on this, the components of the port facility were derived through the codification, categorization, and normalization process developed by the research team. This was extended based on the port BIM object classification system developed by the research team. Normalization results were verified by designers and associations. Then, IFC schema construction was based on Express-G data modeling based on IFC 4 * 2 Candidate, which is a bridge candidate standard based on IFC4 (ISO16739), and IFC 4 * 3 Draft, which is developed by buildingSMART International. The final schema was validated using the commercialized validation tool. In addition, in order to verify the structural verification of the port IFC schema, the transformation process was verified by converting the caisson model into a Part21 file. In the future, this result will not only be used as a delivery standard for port BIM products, but will also be applied as a linkage standard between systems and a common data format for port BIM platforms when BIM is used in the maintenance phase. In particular, it is expected to be used as a core standard for data exchange in the port maintenance stage.