• Title/Summary/Keyword: Cordyceps Sinensis Sacc

Search Result 2, Processing Time 0.015 seconds

Benefical Effect of Cordyceps Sinensis Sacc. Extract (CSS) on Oxidant-Induced Membrane Tpransport Dysfunction in Rabbit Renal Cortical Slices (동충하초약침액(冬蟲夏草藥鍼液)이 가토(家兎) 신피질절편(腎皮質切片)에서 세포막물질이동계(細胞膜物質移動系)의 기능장애(機能障碍)에 미치는 영향(影響))

  • Cheon, Kap-Sool;Seo, Jung-Chul;Youn, Hyoun-Min;Song, Choon-Ho;Ahn, Chang-Beohm;Jang, Kyung-Jeon
    • Journal of Acupuncture Research
    • /
    • v.18 no.3
    • /
    • pp.123-133
    • /
    • 2001
  • Objective : This study was undertaken to determine whether Cordyceps sinensis Sacc. (CSS) extract exerts the protective effect against oxidant-induced alterations in membrane transport function in renal tubules. Methods : Membrane transport fucntion was estimated by examining alterations in p-aminohippurate (PAH) uptake in rabbit renal cortical slices. For induction oxidative stress, slices were treated with an organic peroxide cumene hydroperoxide for 60 min at $37^{\circ}C$. Cumene hydroperoxide inhibited PAH uptake in a time dependent manner. Results : CSS at 0.5-5% concentrations prevented cumene hydroperoxide-induced inhibition of PAH uptake. CSS at 1% also attenuated LDH release and lipid peroxidation induced by cumene hydroperoxide. When slices were treated with 0.2 mM mercury chloride, PAH uptake was inhibited and lipid peroxidation was increased. These changes by mercury were significantly prevented by CSS. Conclusion : These results suggest that CSS prevents oxidant-induced alterations in membrane transport function in rabbit renal cortical slices. Such protective effect of CSS may be attributed to inhibition of peroxidation of membrane lipid.

  • PDF

Status, Distribution, Conservation and Use Value of Medicinal and Aromatic Plants (MAPs) in Sagarmatha National Park, Nepal

  • Gaire, Damodar
    • Journal of Forest and Environmental Science
    • /
    • v.30 no.3
    • /
    • pp.253-258
    • /
    • 2014
  • The study attempts to assess the status, distribution, conservation and use value of Medicinal and Aromatic Plant (MAPs) in the Sagarmatha National Park. Altogether 62 species of MAPs belonging to 47 genera and 33 families have been recorded in the study area. 10 species, belonging to 9 families are categorized as the potential species. Out of the these species, most potential in local but threatened species are Allium hypsistum Stearn, Cordyceps sinensis Sacc, Dactylorhiza hatagirea Soo, Nardostachys grandiflora DC, Aconitum orochryseum, Ephedra gerardiana Wall. Ex. Stapf, Swertia multicaulis D. Don, Picrorhiza scrophulariflora Penne, Rheum australe. D. Don, Malva verticillataL and Swertia pedicallata Benerji. By analysis of data using Simpson's diversity index (SI) and Shannon weaver function (H'), there was high diversity (more heterogeneous) MAPs species composition in the Manjo Gate to Large Dobhan. (0.98349). Less diversity (less heterogeneous) MAPs species composition was in Tyanboche to Pangoche (0.90419). Similarly, the Shannon weaver function shows that in plots laying out in Mongla to Phorche are evenly distributed than others However, higher MAPs species (i.e., 31) was found in the way of Manjo Gate to Larja Dobhan than others.