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Umbilical Cord Blood Transplantation

  • Ahn, Hyo Seop;Shin, Hee Young
    • IMMUNE NETWORK
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    • v.3 no.2
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    • pp.83-88
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    • 2003
  • The number of umbilical cord blood transplantation is increasing worldwide as it has expanded the ability of the transplantaion community to meet the growing needs of their patients. Clinical data over the last decade show promising results in transplantation using both related as well as unrelated cord bloods. Cord blood banks are essential for the clinical use for transplantation and are now established around the world with the major efforts to standardize banking in collection, processing and distribution of cord blood for providing the highest quality stem cells for the patients. In Korea, Medipost, Histostem and some regional cord blood banks were established some years ago and collected thousands of cord blood for public but it had some limitations and was not expanded as the cord blood transplantation was not covered by medical insurance. Recently with the change in the policy of medical insurance to cover the cord blood transplantation, several venture companies are showing great interests in cord blood banking and trying to establish private cord blood banks in Korea. This review article discusses the current status of cord blood transplantaion and also the clincial use of stem cells from cord blood.

Knowledge and Attitude Regard to Cord Blood of Early Postpartum Women after Donating Cord Blood or Storing Cord Blood (제대혈 기증.보관한 산부의 제대혈 관련 지식 및 태도)

  • Kim, Mi-Ok;Yoo, Ji-Soo;Park, Chang-Gi;Ahn, Hyun-Mi
    • Women's Health Nursing
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    • v.15 no.1
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    • pp.13-23
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    • 2009
  • Purpose: There is increasing necessity of using cord blood cell worldwide. In order to improve the effectiveness of cord blood's usage in Korea, the study of knowledge and attitude regarding cord blood is needed. Method: As descriptive correlation study, data was collected from 212 early postpartum women who stored or donated cord blood from 2007 April to July. Data was analyzed using $X^2$-test, t-test, ANOVA, and logistic regression. Result: Total score of knowledge and attitude of early postpartum women who donated cord blood was higher than who stored. According to the source of education and the source of influence toward decision of using cord blood, early postpartum women who educated or influenced by mass media showed difference in attitude. Job status and income, and attitude of cord blood were the predictor of cord blood donation. Conclusion: Attitude regard to cord blood affect to usage of cord blood, and the attitude and knowledge of cord blood in early postpartum women who donated it higher than who stored.

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Comparison of Tension According to the Type of Sling Cord during the Bridging Exercise with Sling in Stroke Patients (뇌졸중 환자의 교각 운동 시 슬링 줄의 종류에 따른 장력 비교)

  • Jang, Gwonuk;Chang, Jongsung
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.2
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    • pp.189-194
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    • 2019
  • Objectives The purpose of this study was to examine comparison of tension according to the type of sling cord during the bridging exercise with sling in stroke patients. Methods Twenty six stroke patients were recruited for this study. Subjects were randomly performed sling bridging exercise with three types of sling cords such as nonelastic cord with affected side-nonelastic cord with non affected side (NC-NC), nonelastic cord with affected side-elastic cord with non affected side (NC-EC), and elastic cord with affected side-nonelastic cord with non affected side (EC-NC). They were measured tension with a tensiometer of sling cord during the bridging exercise with sling. Results The tension of sling cord was significantly different in affected side, non affected side, and tension ratio of affected side/non affected side. There were significant differences tension in NC-EC from NC-NC and EC-NC and the NC-EC method was increased tension of affected side and decreased tension of non affected side. Conclusions These results showed that the NC-EC method was improved the symmetry of affected side and non affected side. Sling exercise with appropriate type of sling cord should be increased activities of affected side and improved recovery in stroke patients.

Nerve-Muscle Pedicle Reinnervation in Bilateral Vocal Cord Palsy (양측성 성대마비에서의 신경-근 이식 수술)

  • 우훈영;김영기;정현수
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.6 no.1
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    • pp.5-8
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    • 1995
  • Bilateral vocal cord palsy is uncommon but is serious because of airway obstruction. Treatments of bilateral vocal cord palsy are initially tracheotomy, vocal cord lateralization and vocal cord reinnervation. Recently, we experienced nerve-muscle pedicle reinnervation in 3 cases of bilateral vocal cord palsy, so reported it with a review of literature.

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Estimation of Incidence Rate and Factors Related to Occurrence of Traumatic Spinal Cord Injury in Seoul (서울지역 외상성 척수손상환자의 발생률 추정 및 발생관련요인)

  • Chung, Nak-Su;Chung, Chee-Kyung;Lee, Won-Chul
    • Physical Therapy Korea
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    • v.6 no.2
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    • pp.1-15
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    • 1999
  • For the purpose of disclosing estimated annual incidence rate and causative factors of traumatic spinal cord injury and obtaining basic data for the establishment of effective measures to prevent this injury, the medical record of 204 cases of Seoul residents with spinal cord injury which admitted in 46 general hospitals and National rehabilitation center located in Seoul, including Sam Yook Rehabilitation Center and Jung Ang Hospital in Kyungi do and occurred in 1995 were analyzed. The results were as follows: 1) The estimated annual incidence rate of traumatic spinal cord injury in 1995 of Seoul residents was 20.5 per million population. This incidence rate was the highest in the 40th years (34.1), followed by in the 50th years (26.5) and in the 20th years (25.6) in descending order. 2) The incidence rate ratio between male and female was 3.5:1. 3) The leading cause of injury was the highest in traffic accidents (42.2%), followed by falls from elevation (29.4%) and falls on the same level (9.8%). 4) Traffic accident mainly occured from 20th years to 40th years and falls from elevation in 50th years. 5) The level of spinal cord injury was the highest in cervical cord (63.2%), followed by the thoracic cord (21.1%) and lumbosacral cord (15.7%). Traffic accidents mainly caused in cervical cord injury whereas thoracic cord injury and lumbosacral cord injury were caused from falls from elevation. Above theconsiderations in mind, it suggested that in order to prevent traumatic spinal cord injuries, safety education of falls from elevation should be focused on the 20th years and 50th years male, moreover safety education of traffic accidents will be needed in the 30th years and 40th years male.

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Folate Levels of Umbilical Cord Blood and Pregnancy Outcomes (한국인 임신 여성의 제대혈 엽산 농도와 임신의 결과)

  • 임현숙
    • Journal of Nutrition and Health
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    • v.31 no.8
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    • pp.1263-1269
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    • 1998
  • The maintenance of adequate folate levels in the umbilical cord blood is esential for supplying tissue requirements of fetal growth. However, there is data on folate levels in the cord blood of Korean infant. The present investigation was undertaken to determine folate levels in cord blood and aassess relationships between folate levels and pregnancy outcomes. Dietary and supplementary folate intake was obtained from thirty subjects who were in the third trimester fo pregancy . The umbilical cord blood was drawn at delivery and pregnancy outcomes for the subjects were collected from their medical records. Erythrocyte and plasma folate levels in the cord blood were analyzed. The subjects were divided into two groups ; high folate (HF, $\geq$654ng/ml) and low folate (LF, <654ng/ml) groups according to erythrocyte folate levels in cord blood. Dietary folate intake and the amount of supplemental folates were not significantly different between the two experimental groups. However, infant birth weight (3540$\pm$295g) and placental weight(910$\pm$85g) for the HF group were significantly higher(p=0.0041 and p=0.109, respectively) than those for the LF group, which were 3127 $\pm$419g and 823$\pm$80g , respectively. Although it was not significant, the gestational weight gain for the HF group was 2.8kg higher than that for the LF group. Thus, the erythrocyte folate level in the cord blood was significantly related to infant birth weight and placental weight. These results confirm that a high erythrocyte folate level in the umbilical cord blood promotes both fetal and placental growth and improves gestational weight gain as well.

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Failure of Tire Belt Cord (타이어 Belt Cord 의 파단)

  • Kim, Seok-Nam;Takashi, Akasaka
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.1394-1400
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    • 2003
  • Tire subjected to inflation pressure and the load of passenger car has a important roll to dynamic performance characteristics of radial tires such as cornering and braking. These performance characteristics are directly related to the belt cord durability of tires. In this paper, we analyze the mechanism of belt cord broken due to cord tension at braking theoretically.

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Unilateral vocal cord paralysis after open heart surgery -A report of 2 cases- (개심술후 발생한 일측성 성대마비 -2례 보고-)

  • 이종욱
    • Journal of Chest Surgery
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    • v.23 no.3
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    • pp.522-526
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    • 1990
  • We have experienced 2 cases vocal cord paralysis after open heart surgery. One was a postoperatively developed right unilateral vocal cord paralysis after prosthetic mitral valve replacement with tricuspid valve annuloplasty. The other was a postoperative left unilateral vocal cord paralysis after prosthetic aortic and mitral valve replacement with tricuspid annuloplasty. They were intubated for forty-eight and seventy-two hours but after extubation complained of hoarseness, aphonia, anxiety, and ineffective coughing Indirect laryngoscopy performed at about postoperative one week, revealed partial paralysis and decreased mobility of the vocal cord. After active phonation therapy, symptoms were improved gradually and in the follow up indirect laryngoscopy, the vocal cord paralysis was improved. The symptoms were recovered completely at about postoperative one month in both. The cause of vocal cord paralysis after open heart surgery may be any retraction or stretching injury to the recurrent laryngeal nerve, especially right side, during median sternotomy retraction and open heart operation procedures. As a result, avoid of excessive spread of median sternotomy retractor and excessive manipulation and retraction of the heart during open heart procedures will reduce the occurrence of the vocal cord paralysis.

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