• Proceedings of the Korean Magnestics Society Conference
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• 2013.12a
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• pp.123-123
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• 2013

• Proceedings of the Korean Magnestics Society Conference
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• 2014.11a
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• pp.148-148
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• 2014

• Journal of Korean Neurosurgical Society
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• v.66 no.5
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• pp.605-608
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• 2023

• Journal of applied mathematics & informatics
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• v.22 no.1_2
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• pp.351-360
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• 2006

In this paper, we develop an inexact-Newton method for solving nonsmooth operator equations in infinite-dimensional spaces. The linear convergence and superlinear convergence of inexact-Newton method under some conditions are shown. Then, we characterize the order of convergence in terms of the rate of convergence of the relative residuals. The present inexact-Newton method could be viewed as the extensions of previous ones with same convergent results in finite-dimensional spaces.

• Journal of Industrial and Engineering Chemistry
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• v.68
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• pp.117-123
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• 2018

Recently, aqueous method has attracted lots of attention because it enables the solution-processed metal oxide thin film with high electrical properties in low temperature fabrication condition to various flexible devices. Focusing the development of aqueous route, many researchers are only focused on metal oxide materials. However, for expansive application of the aqueous-based metal oxide films, the systematic study of performance change with process variables for the development of aqueous-based metal oxide insulator film is urgently required. Here, we propose importance of process variables to achieve high electrical-performance metal oxide insulator based on the aqueous method. We found that the significant process variables including precursor solution temperature and humidity during the spincoating process strongly affect chemical, physical, and electrical properties of $AlO_x$ insulators. Through the optimization of significant variables in process, an $AlO_x$ insulator with a leakage current value approximately $10^5$ times smaller and a breakdown voltage value approximately 2-3 times greater than un-optimized $AlO_x$ was realized. Finally, by introducing the optimized $AlO_x$ insulators to solutionprocessed $InO_x$ TFTs, we successfully achieved $InO_x/AlO_x$ TFTs with remarkably high average field-effect mobility of ${\sim}52cm^2V^{-1}\;s^{-1}$ and on/off current ratio of 106 at fabrication temperature of $250^{\circ}C$.

• Journal of Information Science Theory and Practice
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• v.10 no.spc
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• pp.1-11
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• 2022

As data-based research activities and outcomes increase and ontact or non-face-to-face activities become common, the demand for easy utilization of resources, tools, functions, and easily accessible information required for research in the R&D sector has increased accordingly. With the rapid increase in the demand for collaborative research based on online platforms, research support institutions strive to provide venues for research activities that merge various information and functions. ScienceON, an integrated science & technology (S&T) knowledge infrastructure service developed and operated by the Korea Institute of S&T Information (KISTI), supports open collaboration by connecting and merging all the information, functions, and infrastructure required for research activities. This paper describes the online research activity support tool provided by ScienceON and the remarkable results achieved through this activity. Specifically, the excellent creation of the following flow of meta-material research activities in the ontact space is elucidated. First, the papers required for a meta-material analysis are retrieved, virtual simulation is conducted with the experimental data extracted from the papers, and research data are accumulated. ScienceON's tools for supporting ontact research activity will play a role as an important service in the era of digital transformation and open science.

• Journal of Korean Institute of Industrial Engineers
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• v.42 no.1
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• pp.1-19
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• 2016

Recently, the emergence of smartphone foster the technological convergence. This convergence no longer takes place within technologies only. Rather, convergence phenomena happen as a form of embodied services. However, previous research on convergence has been subject to the technology-oriented studies, including suggesting patent-based indexes or analyzing technological characteristics. However, investigating technology-service convergence is critical since most of new smart services are technology-based convergence services. Therefore, we analyze the pattern of technology-service convergence which occurs in the smartphone application services. We divided the smatphone application services into four categories, and employ a network analysis to represent the convergence phenomena of each category. Our study is expected to provide meaningful implication in new service development practice.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.5
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• pp.451-460
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• 2015

Sirtuin 1 (SIRT1) is a mammalian $NAD^+$-dependent protein deacetylase that regulates cellular metabolism and inflammatory response. The organ-specific deletion of SIRT1 induces local inflammation and insulin resistance in dietary and genetic obesity. Macrophage-mediated inflammation contributes to insulin resistance and metabolic syndrome, however, the macrophage-specific SIRT1 function in the context of obesity is largely unknown. C57/BL6 wild type (WT) or myeloid-specific SIRT1 knockout (KO) mice were fed a high-fat diet (HFD) or normal diet (ND) for 12 weeks. Metabolic parameters and markers of hepatic steatosis and inflammation in liver were compared in WT and KO mice. SIRT1 deletion enhanced HFD-induced changes on body and liver weight gain, and increased glucose and insulin resistance. In liver, SIRT1 deletion increased the acetylation, and enhanced HFD-induced nuclear translocation of nuclear factor kappa B (NF-${\kappa}B$), hepatic inflammation and macrophage infiltration. HFD-fed KO mice showed severe hepatic steatosis by activating lipogenic pathway through sterol regulatory element-binding protein 1 (SREBP-1), and hepatic fibrogenesis, as indicated by induction of connective tissue growth factor (CTGF), alpha-smooth muscle actin (${\alpha}$-SMA), and collagen secretion. Myeloid-specific deletion of SIRT1 stimulates obesity-induced inflammation and increases the risk of hepatic fibrosis. Targeted induction of macrophage SIRT1 may be a good therapy for alleviating inflammation-associated metabolic syndrome.

• Korean Journal of Agricultural Science
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• v.43 no.4
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• pp.612-622
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• 2016

The purpose of this study was to evaluate the effects of sex, birth year, birth season, and parity of sows on their progeny using the following on-farm test records: Backfat Thickness (BF), Fresh Meat Percent (FMP), Loin depth (LD), Age at 90kg (90D), and Average Daily Gain (ADG). Statistical analysis was performed using data collected from 1,178 Yorkshire and 13,395 Landrace progenies, which were born from 119 Yorkshire and 1,191 Landrace sows, respectively between 2011 and 2015. All results of the analysis were statistically significant (P < 0.05) except the birth season effect on LD. For Landrace, the highest ratings were found to be at the $5^{th}$ parity (BF), at the $3^{rd}$ parity (FMP and LD), at the $2^{nd}$ parity (90D and ADG). For Yorkshire, the highest ratings were at the $2^{nd}$ parity (BF and FMP), at the $3^{rd}$ parity (LD), and at the $4^{th}$ parity (90D and ADG). Although the ratings of carcass traits of progeny appear to be higher between the maternal sow's $2^{nd}$ and $4^{th}$ progenitor, no significant relations to parity were found. Based on these results, we concluded that maternal parity is not significantly affect carcass traits of progeny and thus that the best slaughtering age of sows should not be determined solely based on maternal parity but also in consideration of other factors such as unit costs of production. The results of this study would provide fundamental information to future studies on the effect of economical parity on sows and swine breeding.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.317-328
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• 2018

Cognitive impairment responses are important research topics in the study of degenerative brain diseases as well as in understanding of human mental activities. To compare response to scopolamine (SPL)-induced cognitive impairment, we measured altered parameters for learning and memory ability, inflammatory response, oxidative stress, cholinergic dysfunction and neuronal cell damages, in Korl:ICR stock and two commercial breeder stocks (A:ICR and B:ICR) after relevant SPL exposure. In the water maze test, Korl:ICR showed no significant difference in SPL-induced learning and memory impairment compared to the two different ICRs, although escape latency was increased after SPL exposure. Although behavioral assessment using the manual avoidance test revealed reduced latency in all ICR mice after SPL treatment as compared to Vehicle, no differences were observed between the three ICR stocks. To determine cholinergic dysfunction induction by SPL exposure, activity of acetylcholinesterase (AChE) assessed in the three ICR stocks revealed no difference of acetylcholinesterase activity. Furthermore, low levels of superoxide dismutase (SOD) activity and high levels of inflammatory cytokines in SPL-treated group were maintained in all three ICR stocks, although some variations were observed between the SPL-treated groups. Neuronal cell damages induced by SPL showed similar response in all three ICR stocks, as assessed by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay, Nissl staining analysis and expression analyses of apoptosis-related proteins. Thus, the results of this study provide strong evidence that Korl:ICR is similar to the other two ICR. Stocks in response to learning and memory capacity.