• Parasites, Hosts and Diseases
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• 제61권3호
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• pp.263-271
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• 2023

The present study aimed to survey the prevalence of chigger mites and Orientia tsutsugamushi (O. tsutsugamushi) infection in the northern regions of Gangwon-do, Korea. From early February to early June 2015, a total of 17,050 chiggers were collected from striped field mice, Apodemus agrarius, in Cheorwon-gun, Hwacheon-gun, Yanggu-gun, and Goseong-gun, which are well-known endemic areas of scrub typhus in Korea. The chiggers were analyzed using molecular genomic methods, as previously described. Among the 7,964 identified chiggers, the predominant species was Leptotrombidium pallidum (76.9%), followed by L. zetum (16.4%), L. orientale (4.3%), L. palpale (0.3%), L. tectum (0.2%), and Neotrombicula tamiyai (1.8%). The chigger index (CI) was highest in Hwacheon (115.58), followed by Cheorwon (97.02), Yanggu (76.88), and Goseong (54.68). Out of the 79 O. tsutsugamushi-positive chigger pools, 67 (84.8%) were identified as the Boryong strain, 10 (12.7%) as the Youngworl strain, and only 2 were the Jecheon strain. Based on the high infestation of chiggers in striped field rodents and the high rate of O. tsutsugamushi infection in chigger mites, Hwacheon-gun and Cheorwon-gun are presumed to be high-risk areas for scrub typhus. Furthermore, L. pallidum, a major vector of scrub typhus, and the dominant O. tsutsugamushi serotype, the Boryong strain, were found in the northern regions of Gangwon-do, Korea.

• 대한의생명과학회지
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• 제29권2호
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• pp.66-74
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• 2023

Triglyceride (TG) accumulation can cause monocytic death and suppress innate immunity. However, the signaling pathways involved in this phenomenon are not fully understood. This study aimed to examine whether inducible nitric oxide synthase (iNOS) is involved in the TG-induced death of THP-1 monocytes. Results showed that iNOS was upregulated in TG-treated THP-1 monocytes, and iNOS inhibition blocked TG-induced monocytic death. In addition, TG-induced poly (ADP-ribose) polymerase (PARP) cleavage and caspase-3 and -7 activation were suppressed by iNOS inhibition. Furthermore, the expression of X-linked inhibitor of apoptosis protein (XIAP) and survivin, which inhibit caspase-3 and -7, was reduced in TG-treated THP-1 monocytes, but iNOS inhibition recovered the TG-induced downregulation of XIAP and survivin expression. Considering that TG-induced monocytic death is triggered by caspase2 and -8, we investigated whether caspase-2 and -8 are linked to the TG-induced expression of iNOS in THP-1 monocytes. When the activities of caspase-2 and -8 were inhibited by specific inhibitors, the TG-induced upregulation of iNOS and downregulation of XIAP and survivin were restored in THP-1 monocytes. These results suggest that TG-induced monocytic death is mediated by the caspase-2/caspase-8/iNOS/XIAP and survivin/executioner caspase/PARP pathways.

• Journal of information and communication convergence engineering
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• 제9권2호
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• pp.235-243
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• 2011

With the recent trends and the adaptation of further advancement in personal healthcare system leads to develop some application which can work independent and user can operate that application without much interference of physician or any specialist user. To meet these needs, this paper proposes and implements a progressive architecture for the personal healthcare information system. This new architecture will not only play the role of middleware but also provide a analysis tool to process that different sensor data which is collected from different sensors implemented on patient body and environment. After collecting that data, with the help of various developed applications this data can be convert into useful information which will be stored in application server for further use and research. These features can be enabled by simple and effortless interactions of normal users and act autonomously to support their activities. This proposed personal healthcare architecture will also provide analysis report to the doctors and patient or various users for further instructions. The analysis report consists of healthcare data analysis results and history of patients. We are considering healthcare data like ECG, which is an important aspect for basic healthcare need.

• Journal of Multimedia Information System
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• 제2권2호
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• pp.241-248
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• 2015

The safety-critical software in healthcare systems needs more and more perceptive excess among human observation and computer support. It is a challenging conversion that we are fronting in confirming security in healthcare systems. Held in the center are the patients-the most important receivers of care. Patient injuries and fatalities connected to health information technologies commonly show up in the news, contrasted with tales of how health experts are being provided financial motivation to approve the products that may be generating damage. Those events are unbelievable and terrifying, however they emphasize on a crucial issue and understanding that we have to be more careful for the safety and protection of our patients.

• Journal of information and communication convergence engineering
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• 제10권4호
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• pp.337-342
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• 2012

The medical industries are integrated with information technology with mobile devices and wireless communication. The advent of mobile healthcare systems can benefit patients and hospitals, by not only providing better quality of patient care, but also by reducing administrative and medical costs for both patients and hospitals. Security issues present an interesting research topic in wireless and pervasive healthcare networks. As information technology is developed, many organizations such as government agencies, public institutions, and corporations have employed an information system to enhance the efficiency of their work processes. For the past few years, healthcare organizations throughout the world have been adopting health information systems (HIS) based on the wireless network infrastructure. As a part of the wireless network, a mobile agent has been employed at a large scale in hospitals due to its outstanding mobility. Several vulnerabilities and security requirements related to mobile devices should be considered in implementing mobile services in the hospital environment. Secure authentication and protocols with a mobile agent for applying ubiquitous sensor networks in a healthcare system environment is proposed and analyzed in this paper.

• 융합보안논문지
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• 제14권7호
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• pp.75-84
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• 2014

예방 의료에서 유비쿼터스 헬스케어는 노인 환자들의 수명연장에 대한 연구로 발전되고 있다. 이와 같은 연구들은 수명 연장 및 불의의 사고를 예방하기 위하여 모바일과 무선센서 기술을 사용하여 삶의 질을 향상 시켜 수명을 연장시키고 있다. 그러나 인터넷을 통해 유비쿼터스 헬스케어 응용프로그램이 모바일화 및 보급이 용이해짐에 따라 u-헬스정보 보호와 보안에 대한 위협이 증가하고 관심을 받고 있다. 따라서 본 논문에서는 보안 헬스 정보 교환 기술을 적용한 온톨로지를 이용하는 유헬스 케어 어플리케이션의 지식기반 상황인식 서비스 프레임워크를 제안한다. 본 연구에서는 유비쿼터스 컴퓨팅 환경에서 상황 영역의 보안 헬스 정보 교환 기술을 적용한 온톨로지를 위한 보편적인 어플리케이션 영역에서 상황 추론, 상황 모델링, 지식 기반 지원을 적용하는 것이다. 본 논문에서는 예방 서비스 질 변화를 위한 모바일 웹서비스, 상황 기술, 지식베이스에 대하여 논의한다.

• Journal of Multimedia Information System
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• 제4권4호
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• pp.205-210
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• 2017

This paper presents a verification watermarking applied to healthcare information management. The proposed method uses the whole region based on the public-key cryptograph, which is transformed by the DWT transform to integrity verification. Furthermore, the public-key cryptograph algorithm is used for the embedded watermark image. We adaptively select the upper bit-plane including the LSB parts of each block when the watermark is inserted.

• 한국의류산업학회지
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• 제22권5호
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• pp.607-616
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• 2020

Health care wearables are devices that are attached to or combined with the human body to improve the health care capabilities of the human body that can be safely and adjustable according to preference. This study provided direction for future research on healthcare wearables in the field of clothing science, considering trends observed in this field from 2010 to 2019. Over the last 10 years, 812 studies have been conducted on healthcare wearables in Korea. Research has increased significantly since 2015, with a large number of articles published in this field. The research for this study was broken down into the following categories: technology development, marketing analysis, and technology analysis. The results according to the research method demonstrated that development and production methods were used most frequently, followed by trend analysis, experiment and evaluation, and survey. An analysis of keywords in the articles studied revealed that device, healthcare, big data (biometric data and database), and healthcare convergence technologies were trending. Similarly, detailed research on healthcare wearable devices and related technologies was actively being conducted. However, focusing on fiber, textiles, design, and clothing articles, in relation to the field of clothing in healthcare wearables, only 81 articles were found on this topic (10.0%), which was low compared to other studies. Therefore, it was determined that more research on healthcare wearables is necessary in the field of clothing.

• 한국융합학회논문지
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• 제7권4호
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• pp.19-24
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• 2016

정보를 공유하기 위해 사용되어온 인터넷은 사용자들이 유일하게 정보를 송, 수신하는 매개체로 인식되어 왔다. 또한 꾸준한 정보통신 기술의 발전으로 다양한 디바이스들이 개발되어 이용되고 있으며, 이들 디바이스들은 사용자들이 이용하고 있는 형태를 넘어 디바이스들간에도 정보를 주고 받는 환경으로 변화되어 가고 있다. 사물 인터넷 기술은 인터넷을 통해 서로 연결되어 있으면서 사람과 사람뿐만이 아닌 다양한 디바이스들간에도 인터넷을 이용하여 필요한 정보들을 공유하면서 시간과 장소에 구분되지 않으면서, 소통 가능하게 하고 있다. 본 연구에서는 사물인터넷을 이용한 스마트 헬스케어 산업현장의 사례들에 대해 살펴보았으며 각 제품들의 개발 배경 및 서비스 이용 과정 및 절차등을 감안한 앞으로의 발전 가능성에 대해 연구하였다.

• The Journal of Korean Physical Therapy
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• 제33권4호
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• pp.187-192
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• 2021

Purpose: The purpose of the current study was to determine the intra- and inter-rater reliability of muscle thickness measurement of the TA using ultrasonography (US) conducted at different inward pressures of approximately 0.5 kg, 1.0 kg, and no pressure control. Methods: Twenty healthy subjects were recruited for this study. Two different examiners measured the thicknesses of the dominant TA of each subject randomly to assess the intra- and inter-rater reliability. The measurement values were analyzed using the intra-class correlation coefficient (ICC) with a 95% confidence interval, standard error of measurement, minimal detectable change, and coefficient of variance. Results: All intra-rater reliability ICC values showed high reliability above 0.9. Inter-rater reliability ICC values showed high reliability above 0.9 with 0.5 and 1.0 kg of inward pressure. In contrast, Inter-rater reliability ICC values showed poor reliability (0.23) with no pressure control of inward pressure. Conclusion: The findings showed that maintaining consistent inward pressure is essential for reliable results when the muscle thickness of the TA is measured by different examiners in a clinical setting.