• Title/Summary/Keyword: Controversies

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A Critical Review on Setting up the Concept, Timing and Mechanism of Tertiary Tilted Flexural Mode of the Korean Peninsula: A new hypothesis derived from plate tectonics ('신생대 제3기 경동성 요곡운동'의 개념, 시기, 기작에 관한 비판적 고찰: 판구조운동 기원의 새로운 가설)

  • Shin, Jaeryul;Hwang, Sangill
    • Journal of the Korean Geographical Society
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    • v.49 no.2
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    • pp.200-220
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    • 2014
  • This study reexamines the old concept and reviews prevalent statements on Cenozoic vertical motions of the peninsula that have been uncritically repeated in our academia. The contents of this paper are redefinition of the notion, tilted flexure or warping, and a suggestion for a new time set and properties of the deformation, followed by a new model on its influencing factors and processes. In conclusion, the Cenozoic vertical motion of the Korean peninsula can be reified further with an epeirogenic movement of uplift in the east side-subsidence in the west side of the peninsula since the Neogene (23 Ma). However, the regional boundary for areas of uplift and subsidence is not likely in the Korean peninsula but broader farther to East China and the southern part of Russia. It can be best understood that mantle convection produced by subducting activities in the Western Pacific Subduction Zone causes the uplift and subsidence of earth surface around NE Asia. In addition, faultings in the upper lithosphere induced by in-situ plate boundary stresses accelerate regional uplift in the peninsula since the Quaternary. Controversies that are still standing such as current uplift movements along the western coast of the peninsula during the late Quaternary could be precisely discussed with future research providing detailed information on it.

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Prognostic Factors and Survival Rates of Stage III Gastric Cancer Patients after a Gastrectomy (3기 위암 환자의 술 후 생존율 및 예후 인자 분석)

  • Jang Seok-Won;Kim Chi-Ho;Kim Sang-Woon;Song Sun-Kyo
    • Journal of Gastric Cancer
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    • v.4 no.3
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    • pp.137-142
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    • 2004
  • Purpose: There have been some controversies over the therapeutic principles of advanced gastric cancer, and the results of treatment have been variable, especially for stage III disease. This study was conducted to define the prognostic factors of stage III gastric cancer. Materials and Methods: This retrospective study was based on the medical records of 179 patients with stage III disease who received a gastrectomy from January 1990 to December 1994. The 5-year survival rate was analyzed according to the age, sex, tumor location, tumor size, Borrmann's type, depth of invasion, lymph-node metastasis, ratio of metastatic lymph nodes, type of surgical resection, extent of lymphnode dissection, curability of resection, postoperative chemotherapy, and pathological stage. The statistical analysis was done by using the Kaplan-Meier method, the log-rank test, and the Cox proportional hazards model. Results: The overall 5-year survival rate was $61.6\%$ the 5-year survival rates according to subgroup were $69.7\%$ for stage IIIa ($100\%$ for $T_{2}N_{2}$, $70.0\%$ for $T_{3}N_{1}$, $68.6\%$ for $T_{4}N_{0}$), and $54.1\%$ for stage IIIb ($T_{3}N_{2}$) (P<0.05). Among various clinicopathologic factors of stage III gastric cancer, the age of the patient, the tumor location, the gross type of tumor, the type of gastric resection, the extent of lymph-node dissection, the curability of resection, and the subgroups of stage III were statistically significant in the univariate survival analysis. The multivariate analysis defined the curability of resection, the extent of lymph-node dissection, the type of operation, the stage of disease, and the age of the patient as independent prognostic factors. Conclusion: A curative surgical resection and an extended lymph-node dissection are thought to be most important for improving the survival rate in stage III gastric cancer patients.

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Clinicopathological Significance of p53 and HSP27 in Gastric-cancer Patients (위암 환자에서 p53과 HSP27의 임상병리학적 의의)

  • Lee, Ha-Gyoon;Kwon, Sung-Joon;Baek, Seung-Sam
    • Journal of Gastric Cancer
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    • v.4 no.3
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    • pp.169-175
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    • 2004
  • Purpose: The tumor suppressor gene p53 has been shown to be a factor in the carcinogenesis or progression of gastric cancer. The mutant p53 has been reported to cause a higher risk of lymph-node metastasis. Futhermore, mutation of the p53 has been linked to a poor prognosis for gastric cancer. The heat shock protein-27 (HSP27), a stress protein, has also been reported to be a poor prognostic factor in ovarian and breast cancers. However, in gastric-cancer patients, controversies exist as to its influence on the prognosis. In the present study, we used an immunohistochemical stain to observe the effects of p53 and HSP27 on the clinicopathological factors and on the prognosis for gastric-cancer patients. Materials and Methods: To evaluate the significance of p53 and HSP27 in gastric cancer patients, we analyzed 212 cases of gastric cancer (stage I.IV). Tissue samples of 212 patients were stained immunohistochemically for the mutant p53 protein and for HSP27. The correlations between protein expression and the clinicopathological factors were investigated. Results: The overall expression rates for p53 and HSP27 were $36.9\%\;and\;27.8\%$, respectively. p53 and HSP27 were correlated to each other because the HSP27 expression rate was higher in the p53-positive group (P=0.046). Statistically, the p53 and the HSP27 expression rates were significantly increased in the case of tumor invasiveness, lymphatic metastasis and vessel involvement. Therefore, they play a role in cancer progression. The 5-year survival rates of the p53-positive and the p53-negative groups were $62.8\%\;and\;60.1\%$, respectively (P=0.793) while the 5-year survival rates for the HSP27-positive and HSP27-negative groups were $54.2\%\;and\;63.1\%$, respectively (P=0.090). Conclusion: p53 and HSP27 were correlated to each other in our immunohistochemical study of gastric carcinomas and they were not independent prognostic factors in gastric- cancer patients. However, further studies are needed to determine their prognostic values for gastric-cancer patients.

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THE EXPERIMENTAL STUDY ON THE CHANGES OF CONDYLAR HEAD FOLLOWING UNILATERAL DISCECTOMY IN RABBIT (가토 편측 악관절원판 제거 후 하악 과두 변화에 관한 실험적 연구)

  • Park, Kwang-Jin;Kim, Kyung-Wook
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.4
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    • pp.758-770
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    • 1996
  • Discectomy is the oldest and most commonly performed operation for the painful temporomandibular joint with internal derangement. It is the one operation for which there are longest follow-up study, with Eriksson, Silver, and Tolvanen et al reporting good results in patients about 30 years after discectomy. About 80% to 90% of patients clinically experience relief from pain and dysfunction after discectomy, and interestingly, the results may improve with time. However such as Myrhaug found headache and Poswillo supposed pain and limitation of movement as postoperative complications, even though this operation had the longest follow-up term, several aspects of discectomy remain unclear. The controversies to discectomy for TMJ with pain and dysfunction have laid emphasis only upon clinical results, and then the histomorphological study was planned to evaluate the morphologic change of TMJ after discectomy. To clarify the nature of the change through an observation on the morphologic changes of articular cartilage and subchondral bone of the condyle resulting from experimental unilateral discectomy in rabbit, the author excised the left articular discs of 12 male rabbits(control 4 rabbits), weighing about 3kg, and at 1, 3, 6, 9 weeks following surgery, harvested both(left surgical site and right nonsurgical sits) TMJ. The specimens were examined with light microscope after H-E and MT stain and the obtained results were as follows. 1. Histopathological features showed thickening of articular zone and active proliferation of fibrocartilaginous zone associated with slight proliferative zone in surgical site than control group. Also replacement of chondrocytes in calcified cartilaginous zone into bone cells was observed. 2. There were thinning of thickness of each zone of articular cartilage except calcified cartilagnous zone was observed in nonsurgical site. 3. In MT stain of condylar trabeculae, there was increased calcification in nonsurgical site than control and surgical site and the degree of calcification was similar in surgical site and control group. 4. In both site of experimental group no features of degenerative changes were observed. From the above results, it is presumed that the morphologic changes of surgical site discectomy are compensatory remodeling process characterized by an hyperplastic reaction of the articular zone and fibrocartilaginous zone filling the void created by removing the disc, and the bone changes are secondary to changes in the cartilage. Increased degree of calcification seen in condylar trabeculae of nonsurgical site results from the excessive use of condyle of that site.

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A COMPARATIVE STUDY ABOUT THE POSITION OF UPPER AND LOWER JAWS, AND FIRST MOLARS IN NORMAL OCCLUSION AND ANGLE'S CLASS $I{\cdot}II{\cdot}III$ MALOCCLUSIONS (정상교합과 부정교합에서의 상${\cdot}$하악골과 제 1 대구치 위치에 관한 비교연구)

  • Yun, Byoung-Mo;Ahn, Byoung-Keun;Rhee, Geon-Ju;Kim, Sun-Hae;Park, Young-Ju;Han, Ho-Jin
    • The korean journal of orthodontics
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    • v.23 no.4 s.43
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    • pp.633-644
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    • 1993
  • There has been so much controversies about the position of upper and lower jaws, and their first permanent molars in normal occlusion and Angle's class $I{\cdot}II{\cdot}III$ malocclusions. So, the purpose of this study is to compare the position of upper and lower jaws, and their first molars in normal occlusion and Angle's class $I{\cdot}II{\cdot}III$ malocclusions by lateral cephalometric analysis. The sample consisted of one hundred and twenty girls(thirty in each group) who had completed growth. The findings of this study were as follows : 1. In class I malocclusion, both maxilla and mandible were slightly posterior position than normal occlusion, but they showed harmonious relationship. 2. In class II malocclusion, the mandible was greatly retruded, and the maxilla was also slightly retruded to the cranial base as compared with normal occlusion. 3. In class III malocclusion, the maxilla was significantly retruded to the cranial base, but no significant difference was found in mandibular position as compared with normal occlusion. 4. The maxillary first molar was located at posterior position in class II malocclusion, and anterior position in class III malocclusion to the cranium, so that the rotation of mandible was influenced by that. 5. The mandibular first molar showed constant relationship to the mandible in all four groups, but different position to the cranial base in direct proportion to the mandibular position. 6. On the treatment planning of class III malocclusion, it seems to be better to promote the mandibular horizontal growth by inhibiting the vertical growth of maxillary molar area, and on the treatment planning of class III malocclusion, it seems to be better to promote the antero-inferior growth of maxilla mi to promote the mandibular vertical growth by inducing the vertical growth of maxillary molar area.

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Study on Vulnerability of Multi-Culturalism Discourses in Korea A Case Study of JTBC's Entertainment Show (텔레비전 예능 프로그램 속의 다문화주의 JTBC <비정상회담>의 '기미가요' 논란을 통해 본 다문화주의 담론의 취약성 연구)

  • Kim, Taeyoung;Yoon, Tae-Jin
    • Korean journal of communication and information
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    • v.77
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    • pp.255-288
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    • 2016
  • Korean mass media has represented foreigners in their documentaries, entertainment shows, situational comedies, and dramas for long time, while the representations created plenty of controversies. Alleged West-oriented racism found from various televison programs may be one of them. Recently, however, more Korean television shows began to incorporate the ideas of multi-culturalism. This paper is an attempt to explore how television audiences interpret multi-culturalism reflected in the media. More specifically, this is a case study of JTBC's , a show featuring foreigners debating on various topics regarding Korean culture. Particularly, it focuses on disputes over the producers' decision to play 'Kimigayo' (the national anthem of Japan, which is also considered as a symbol of Japanese militaristic past) when introduced a new Japanese panel. Critical discourse analysis was adoped as the main research method, and researchers found that audiences draw certain guidelines in accepting multi-cultural aspects. If and when these aspects overstep the line, they tend to abandon it without hesitance. In the case of 'Kimigayo,' it was ethno-centrism and/or anti-Japanes sentiments which made multi-culturalsim much weaker. It does not mean that multi-culturalism was replaced-or defeated-by nationalism, but show the 'vulnerability' of multi-culturalsim. Multi-culturalism is not as concretely rooted in Korean society as many people have claimed or hoped. The research has its own limitations as a case study, but it is hoped to stimulate other researchers to keep their eyes on media and multi-culturalsim in Korea.

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A History of the Korean Association for Communication & Information Studies (KACIS) for 20 Years (한국언론정보학회 20년, 비판적 학술운동의 고민과 한계)

  • Kim, Suh-Jung;Kim, Eun-Gyoo
    • Korean journal of communication and information
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    • v.43
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    • pp.47-80
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    • 2008
  • KACIS was established in 1988 for critical academic movement in communication area. For 20 years after establishment, KACIS has grown into major academic society. The purpose of this article is reflection on the history of KACIS for 20 years. For this, this article review three areas on KACIS. First, It examine how critical academic movement that was initiated in middle of 1980s was changed in gear with Korean Society's shift. Second, It turn around the activity of 'Korean study group for society and communication', the predecessor of KACIS, which operate during $1988{\sim}1998$. Third, it consider KACIS's activity after convert to association, during $1998{\sim}2008$. When look back to 20 years of KACIS, first of all, the biggest fruit is to extend critical communication in academic area. However, several controversies exist about KACIS's identity. Conclusively, this article emphasize, for further development, organizing organic academic conference about social pending issue, strengthening journal's identity, fostering future academic generation, vitalizing research divisions.

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The Significance of Lymphatic, Venous, and Neural Invasion as Prognostic Factors in Patients with Gastric Cancer (위암 환자의 예후인자로서 림프관 정맥 및 신경 침범의 의의)

  • Kim Chi-Ho;Jang Seok-Won;Kang Su-Hwan;Kim Sang-Woon;Song Sun-Kyo
    • Journal of Gastric Cancer
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    • v.5 no.2
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    • pp.113-119
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    • 2005
  • Purpose: Some controversies exist over the prognostic values of lymphatic, venous, and neural invasion in patients with gastric cancer. This study was conducted to confirm the prognostic values of these histopathologic factors in gastric cancer patients who received a gastrectomy. Materials and Methods: Data for clinicopathologic factors and clinical outcomes were collected retrospectively from the medical records of 1,018 gastric cancer patients who received a gastrectomy at Yeungnam University Medical Center between January 1995 and December 1999. A statistical analysis was done using the SPSS program for Windows (Version 10.0, SPSS Inc., USA). The Kaplan-Meier method was used for the survival analysis. Prognostic factors were analyzed by using a multivariate analysis with Cox proportional hazard regression model. Results: Ages ranged from 21 to 79 (median age, 56). A univariate analysis revealed that age, tumor size, location, gross type, depth of invasion, extent of gastrectomy or lymph node dissection, lymph node metastasis, distant metastasis, lymphatic invasion, venous invasion, neural invasion, pathologic stage, histologic type, and curability of surgery had statistical significance. Among these factors, lymph node metastasis, curability of surgery, neural invasion, lymphatic invasion, and depth of invasion were found to be independent prognostic factors by using a multivariate analysis. Venous invasion showed no prognostic value in the multivariate analysis. Conclusion: Neural invasion and lymphatic invasion are useful parameters in determining a prognosis for gastric cancer patients.

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In vivo 3-dimensional Kinematics of Cubitus Valgus after Non-united Lateral Humeral Condyle Fracture

  • Kim, Eugene;Park, Se-Jin;Lee, Ho-Seok;Park, Jai-Hyung;Park, Jong Kuen;Ha, Sang Hoon;Murase, Tsuyoshi;Sugamoto, Kazuomi
    • Clinics in Shoulder and Elbow
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    • v.21 no.3
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    • pp.151-157
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    • 2018
  • Background: Nonunion of lateral humeral condyle fracture causes cubitus valgus deformity. Although corrective osteotomy or osteosynthesis can be considered, there are controversies regarding its treatment. To evaluate elbow joint biomechanics in non-united lateral humeral condyle fractures, we analyzed the motion of elbow joint and pseudo-joint via in vivo three-dimensional (3D) kinematics, using 3D images obtained by computed tomography (CT) scan. Methods: Eight non-united lateral humeral condyle fractures with cubitus valgus and 8 normal elbows were evaluated in this study. CT scan was performed at 3 different elbow positions (full flexion, $90^{\circ}$ flexion and full extension). With bone surface model, 3D elbow motion was reconstructed. We calculated the axis of rotation in both the normal and non-united joints, as well as the rotational movement of the ulno-humeral joint and pseudo-joint of non-united lateral condyle in 3D space from full extension to full flexion. Results: Ulno-humeral joint moved to the varus on the coronal plane during flexion, $25.45^{\circ}$ in the non-united cubitus valgus group and $-2.03^{\circ}$ in normal group, with statistically significant difference. Moreover, it moved to rotate externally on the axial plane $-26.75^{\circ}$ in the non-united cubitus valgus group and $-3.09^{\circ}$ in the normal group, with statistical significance. Movement of the pseudo-joint of fragment of lateral condyle showed irregular pattern. Conclusions: The non-united cubitus valgus group moved to the varus with external rotation during elbow flexion. The pseudo-joint showed a diverse and irregular motion. In vivo 3D motion analysis for the non-united cubitus valgus could be helpful to evaluate its kinematics.

Prognosis of Bochdalek Hernia in Neonate after Change in Management Principle (치료 원칙 변화에 따른 신생아 Bochdalek 탈장의 예후)

  • Seo, Jin-Young;Nam, So-Hyun;Kim, Dae-Yeon;Kim, Seong-Chul;Kim, Ai-Rhan E.;Kim, Ki-Soo;Pi, Soo-Young;Kim, In-Koo
    • Advances in pediatric surgery
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    • v.12 no.2
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    • pp.192-201
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    • 2006
  • There are considerable controversies in the management of congenital diaphragmatic hernia. By 1997, early operation, routine chest tube on the ipsilateral side and maintainingrespiratory alkalosis by hyperventilation were our principles (period I). With a transition period from 1998 to 1999, delayed operation with sufficient resuscitation, without routine chest tube, and permissive hypercapnia were adopted as our practice. High frequency oscillatory ventilation (HFOV) and nitric oxide (NO) were applied, if necessary, since year 2000(period II). Sixty-seven cases of neonatal Bochdalek hernia from 1989 to 2005 were reviewed retrospectively. There were 33 and 34 cases in period I and II, respectively. The neonatal survival rates were 60.6 % and 73.5 %, respectively, but the difference was not significant. In period I, prematurity, low birth weight, prenatal diagnosis, inborn, and associated anomalies were considered as the significant poor prognostic factors, all of which were converted to nonsignificant in period II. In summary, improved survival was not observed in later period. The factors considered to be significant for poor prognosis were converted to be nonsignificant after change of the management principle. Therefore, we recommend delayed operation after sufficient period of stabilization and the avoidance of the routine insertion of chest tube. The validity of NO and HFOV needs further investigation.

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