• Title/Summary/Keyword: Control Transition

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Effects of Pressure Assisted Freezing on Physicochemical Properties of Pork (Pressure Assisted Freezing이 돈육의 이화학적 특성에 미치는 효과)

  • Hong, Geun-Pyo;Ko, Se-Hee;Choi, Mi-Jung;Min, Sang-Gi
    • Food Science of Animal Resources
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    • v.27 no.2
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    • pp.190-196
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    • 2007
  • This study was carried out to investigate the effects of pressure assisted freezing(PAF) on physicochemical properties of pork meat. Pork meat was frozen under pressure up to 200 MPa at $-60^{\circ}C$, and compared with fresh control. Phase transition temperature decreased with increasing pressure level, while pressure level had no effect on supercooling extent. Increasing pressure level increased pH of meat significantly(p<0.05). Thawing losses of all treatments were significantly higher(p<0.05) than control with the exception of PAF at 200 MPa. Water holding capacity(WHC) was increased significantly(p<0.05) with increasing pressure level up to 100 MPa. Cooking loss tended to decrease with increasing pressure level. In color, CIE $L^*-\;and\;b^*-value$ increased with increasing pressure level, while CIE $a^*-value$ decreased significantly(p<0.05). Increasing pressure level up to 150 MPa increased shear force significantly(p<0.05), however, no significant difference between 150 and 200 MPa in shear force was found(p>0.05). Therefore, the results indicated that excessive pressure level in PAF caused several losses in meat qualities, while PAF at mild pressure level improved meat qualities compared to atmosphere freezing.

Harmony Arrangements using B-Spline Tension Curves (B-스플라인 텐션 곡선을 이용한 음악 편곡)

  • Yoo, Min-Joon;Lee, In-Kwon;Kwon, Dae-Hyun
    • Journal of the HCI Society of Korea
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    • v.1 no.1
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    • pp.1-8
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    • 2006
  • We suggest a graphical representation of the tension flow in tonal music using a piecewise parametric curve, which is a function of time illustrating the changing degree of tension in a corresponding chord progression. The tension curve can be edited by using conventional curve editing techniques to reharmonize the original music with reflecting the user's demand to control the tension of music. We introduce three different methods to measure the tension of a chord in terms of a specific key, which can be used to represent the tension of the chord numerically. Then, by interpolating the series of numerical tension values, a tension curve is constructed. In this paper, we show the tension curve editing method can be effectively used in several interesting applications: enhancing or weakening the overall feeling of tension in a whole song, the local control of tension in a specific region of music, the progressive transition of tension flow from source to target chord progressions, and natural connection of two songs with maintaining the smoothness of the tension flow. Our work shows the possibility of controlling the perceptual factor (tension) in music by using numerical methods. Most of the computations used in this paper are not expensive so they can be calculated in real time. We think that an interesting application of our method is an interactive modification of tension in background music according to the user's emotion or current scenario in the interactive environments such as games.

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Women Leaders: Gender Roles, Trust, and Effects on Organizational Performance in Educational Material Distribution Enterprises (여성 리더의 성 역할과 신뢰가 조직 유효성에 미치는 영향: 교육교재 유통기업을 대상으로)

  • Lee, Nam-Gyum;Hwang, Il-Young
    • Journal of Distribution Science
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    • v.13 no.3
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    • pp.93-100
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    • 2015
  • Purpose - Since the early 1990s, it has been observed that the number and substance of studies on female leadership have been increasing. One of the reasons for this development may be concerned with the increasing number of female labor market participants as well as the greater opportunities for them to take higher positions in various organizations. In addition to this, the transition from mechanistic organizational structures that emphasize authority, control, and efficiency toward organic ones that focus on environmental adaptability, equality, and trust has also encouraged research on female leadership. The research tendency is based on the assumption that male and female leaders tend to exhibit different leadership styles according to their gender differences. Recent research has cast doubt on this assumption, by showing that the sociological gender roles of men and women are independent such that some female leaders show authoritative and control-oriented leadership, which were once considered to be male leadership styles. Research design, data, and methodology - This research attempts to carry out an empirical study on the gender-related leadership styles of female leaders and to examine their effect on group performance in the K business organization. This study also focuses on leader attributes such as trust, and it aims to discover whether these attributes should be regarded as independent or as moderating variables between leadership styles and performance. For these purposes, this study generated four hypotheses based on a review of the literature and it tested them using a survey. Female workers in the sales departments of the K Company, all of whom are women, were asked to provide answers to the presented questionnaires. This study hypothesizes that the type of gender roles played by women leaders will affect the job satisfaction and organizational commitment among the members of the sales group, and that the level of trust that is garnered by women leaders will also affect the types of gender roles that they play as well as employee job satisfaction and organizational commitment. Results - The results of this study show that both androgynous and masculine leadership styles are superior to the feminine leadership style in terms of employee job satisfaction and organizational commitment. However, contrary to our expectations, this study fails to show the superiority of the androgynous leadership style over the masculine leadership style. Moreover, there are no significant differences between these two leadership styles with regard to group performance. Conclusions - This study shows that it is important that different attributes of leaders, such as how trusted they are, be treated as moderating variables between leadership and performance rather than as independent variables. Finally, as this is the first attempt to view the role of the gender in a new perspective, the managerial implications of this study for leadership research, as well as its limitations, are presented. Suggestions for future related research are also proposed.

Overexpression of CD44 Standard Isoform Upregulates HIF-1α Signaling in Hypoxic Breast Cancer Cells

  • Ryu, Dayoung;Ryoo, In-geun;Kwak, Mi-Kyoung
    • Biomolecules & Therapeutics
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    • v.26 no.5
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    • pp.487-493
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    • 2018
  • Cluster of differentiation 44 (CD44), a cell surface receptor for hyaluronic acid (HA), is involved in aggressive cancer phenotypes. Herein, we investigated the role of the CD44 standard isoform (CD44s) in hypoxia-inducible $factor-1{\alpha}$ ($HIF-1{\alpha}$) regulation using MCF7 overexpressing CD44s (pCD44s-MCF7). When pCD44s-MCF7 was incubated under hypoxia, levels of $HIF-1{\alpha}$, vascular endothelial growth factor, and the $HIF-1{\alpha}$ response element-derived luciferase activity were significantly increased compared to those in the control MCF7. Incubation of pCD44s-MCF7 cells with HA further increased $HIF-1{\alpha}$ accumulation, and the silencing of CD44s attenuated $HIF-1{\alpha}$ elevation, which verifies the role of CD44s in $HIF-1{\alpha}$ regulation. In addition, the levels of phosphorylated extracellular signal-regulated kinase (ERK) was higher in hypoxic pCD44s-MCF7 cells, and $HIF-1{\alpha}$ accumulation was diminished by the pharmacological inhibitors of ERK. CD44s-mediated $HIF-1{\alpha}$ augmentation resulted in two functional outcomes. First, pCD44s-MCF7 cells showed facilitated cell motility under hypoxia via the upregulation of proteins associated with epithelial-mesenchymal transition, such as SNAIL1 and ZEB1. Second, pCD44s-MCF7 cells exhibited higher levels of glycolytic proteins, such as glucose transporter-1, and produced higher levels of lactate under hypoxa. As a consequence of the enhanced glycolytic adaptation to hypoxia, pCD44s-MCF7 cells exhibited a higher rate of cell survival under hypoxia than that of the control MCF7, and glucose deprivation abolished these differential responses of the two cell lines. Taken together, these results suggest that CD44s activates hypoxia-inducible $HIF-1{\alpha}$ signaling via ERK pathway, and the $CD44s-ERK-HIF-1{\alpha}$ pathway is involved in facilitated cancer cell viability and motility under hypoxic conditions.

Impact of Population Growth on Labor Force and Employment in Korea; Transition and Prospect (장기인구성장과 노동력 수급 전망)

  • 박래영
    • Korea journal of population studies
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    • v.8 no.1
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    • pp.47-65
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    • 1985
  • Three stages of population growth during last forty years affected differently to the labor force and employment in Korea. The first impact of rapid population growth on the labor force occured after the end of World War II. Sudden growth of population due to repartriation and refugees directly increased the labor force. Deteriorating labor market conditions were caused not only by the explosive labor supply but also by the shortage of employment opportunities due to a lack of productive facilities. This severe excess supply of labor continued until the early 196Os. Population growth in the second stage which caused by high fertility during the post Korean War baby boom period induced an eventual increase in the labor supply with time lag of more than fifteen years. Younger persons born during baby boom period were flooded the labor market. Fortunately, job opportunities were expanded more rapidly than the labor force supply because high rates of economic growth and speedy industrialization were continued until the later half of 1970s. Unemployment, therefore, decreased dramatically during this period. The effect of third stage which is characterized as mitigated population growth due to birth control has appeared in the labor market since late 1970s. The growth rate of labor force has been going down and the proportion of younger workers was also been decreasing. From the early 1980s, furthermore, partial disharmony between supply of and demand for the younger workers is closing up. Less educated younger workers who works at low wage are lacking while more educated youngers who want to work at high wage are being excess, because a lot of younger prefer higher education rather than productive job. It is expected that the structural inharmony will be diversified in the future in Korea. The labor force will be changed to middleaged, highly educated and womenized till year 2000, and, after then, to old-aged. On the demand side, industries and jobs will transferred to be labor-saving and soft. These structural changes of labor supply and demand will not matching in time. Aggregate supply of labor force will be steadily increasing more rapidly than aggregate demand for labor until year 2000, and this trend will continue to the first one or two decades of the 2lth century because the persons born dufing the baby boom pariod are being eligible couples in recent. Therefore, conclusion is that appropriate manpower development policy as well as sustained birth control policy is necessary for harmonizing the structural unbalance and the disequilibrium between aggregate labor supply and demand in the future.

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Development and Application of Cognitive Scaffolding Tools for Enhancing the Integrated Science Process Skills of High School Students (고등학생들의 통합 탐구 기능 향상을 위한 인지적 스캐폴딩 도구 개발 및 적용)

  • Lee, Kiyoung;Heo, Junhyuk;Park, Jaeyong
    • Journal of The Korean Association For Science Education
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    • v.39 no.4
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    • pp.545-562
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    • 2019
  • The purpose of this study is to develop cognitive scaffolding tools and to explore their effects on integrated science process skills of high school students. For this purpose, we developed cognitive scaffolding tools including one kind of classroom instruction for training integrated process skills and two kinds of individual learning materials that students can selectively study according to their level of inquiry ability. In addition, we developed hypothetico-deductive inquiry tasks as a tool to investigate the level of students on the integrated process skills for pre-test and post-test respectively. In order to verify the effectiveness of the cognitive scaffolding tools, we conducted inferential statistics on the pre-and post-tests of the experimental group and control group to examine statistical significance of students' inquiry level change depending on the usage of the cognitive scaffolding tools. We also produced Wrightmaps based on Rasch model to compare the change of inquiry ability depending on usage of the cognitive scaffolding tools. As a result, the experimental group using the cognitive scaffolding tools showed a significantly higher scores in all the components of integrated process skills namely, designing inquiry, collecting data, analyzing data, and forming conclusion than the control group. In addition, students who used cognitive scaffolding tools improved their inquiry ability and showed a distinct transition to higher level in each component of the integrated process skills. The results of this study suggest that high school students need cognitive scaffolding to alleviate or eliminate the functional barriers they face in conducting scientific inquiries.

mRNA Expression of the Regulatory Factors for the Early Folliculogenesis in vitro (체외배양 중인 생쥐 난소에서 초기난포 조절인자의 발현)

  • Yoon, Se-Jin;Kim, Ki-Ryeong;Chung, Hyung-Min;Yoon, Tae-Ki;Cha, Kwang-Yul;Lee, Kyung-Ah
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.3
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    • pp.207-216
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    • 2005
  • Objective: To understand the crucial requirement for the normal early folliculogenesis, we evaluated molecular as well as physiological differences during in vitro ovarian culture. Among the important regulators for follicle development, anti-Müllerian hormone (AMH) and FSH Receptor (FSHR) have been known to be expressed in the cuboidal granulosa cells. Meanwhile, it is known that c-kit is germ cell-specific and GDF-9 is also oocyte-specific regulator. To evaluate the functional requirement for the competence of normal follicular development, we investigated the differential mRNA expression of several factors secreted from granulosa cells and oocytes between in vivo and in vitro developed ovaries. Materials and Methods: Ovaries from ICR neonates (the day of birth) were cultured for 4 days (for primordial to primary transition) or 8 days (for secondary follicle formation) in ${\alpha}$-MEM glutamax supplemented with 3 mg/ml BSA without serum or growth factors. The mRNA levels of the several factors were investigated by quantitative real-time PCR analysis. Freshly isolated 0-, 4-, and 8-day-old ovaries were used as control. Results: The mRNA of AMH and FSHR as granulosa cell factors was highly increased according to the ovarian development in both of 4- and 8-day-old control. However, the mRNA expression was not induced in both of 4- and 8-day in vitro cultured ovaries. The mRNA expression of GDF-9 known to regulate follicle growth as an oocyte factor was different between in vivo and in vitro developed ovaries. In addition, the transcript of GDF-9 was expressed in the primordial follicles of mouse ovaries. The mRNA expression of c-kit was not significantly different during the early folliculogenesis in vitro. Conclusion: This is the first report regarding endogenous AMH and FSHR expression during the early folliculogenesis in vitro. In conclusion, it will be very valuable to evaluate cuboidal granulosa cell factors as functional marker(s) for normal early folliculogenesis in vitro.

Studies on the Characteristics of Rubber Vulcanization Exotherm by Differential Scanning Calorimetry. (Differential Scanning Calorimetry에 의(依)한 고무의 가황발열특성(加黃發熱特性)에 관(關)한 연구(硏究))

  • Choi, Sei-Young;Paik, Nam-Chul
    • Elastomers and Composites
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    • v.19 no.1
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    • pp.13-31
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    • 1984
  • The purposes of this dissertation are to demonstrate that DSC theromoanaytical methods of vulcanization can provide useful informations on the vulcanization characteristics of industrial formulations and also provides the potential basis for a rapid and complete method of sulfur and vulcanizing accelerator analysis for quality control. The influences of those factors such as heating rate, scan temperature, vucanizing accelerator's type and concentration upon vulcanization exotherm in NR and NBR compounds in the presence of vulcanizing accelerators such as TMTD,MBTS,DPG,TMTM,CBS, and MBT were evaluated by means of DSC. In order to examine the credibility in the DSC method, the same samples which were used for DSC method were studied to compare the DSC results with the ODR (Oscillating Disk Rheometer) data. The results obtained were as follows 1. In the DSC dynamic experiments, the observed enthalpy results from vulcanization depends upon the heating rate; In the range of 2 to $20^{\circ}C/min$ of heating rate, as the heating rate was increased the enthalpy change was also increased. However, over the heating rate of $30^{\circ}C/min$ it was observed that the enthalpy change was decreased as the heating rate was further increased. Without regard to the change of enthalpy, tremendous instantaneous heat evolving was observed in the range of high heating rates. 2. For the samples which are added with various vulcanizing accelerators, the activation energies of vulcanization were as follows; 3. Regarding to the influences of vulcanizining accelerator's types upon the characteristics of vulcanization exotherm, NR and NBR compounds in the presence of thiuramsulphide compounds type accelerators such as TMTD, TMTM, were exhibited sharper and higher vulclanization exotherm than others. From the resuts of DSC thermograms which was distributed in even shape in the broad temperature range, it was clearly shown that the guanidine compounds type accelerator such as DPG acts as a delayed acting accelerator. 4. In the comparison of DSC and ODR results, the dependency of temperature in the cure rate and the observed conversions show good agreements between two results. 5. In the same curatives, by the comparison of glass transition temperatures, it was possible to predict relative values of maximum torques. Consequently, from the present studies, it is shown that the DSC thermoanalytical method can provide an alternate new method for rapid and complete quality control analysis of rubber industry.

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A Study on the Water Quality Improvement of Major Tributaries in Seoul, Applying Watershed Evaluation Techniques (총량관리 단위유역 평가기법을 활용한 서울특별시 주요 유입 지천의 수질개선효과에 관한 연구)

  • Shim, Kyuhyun;Kim, Gyeonghoon;Im, Taehyo;Kim, Youngseok;Kim, Seongmin
    • Journal of Korean Society on Water Environment
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    • v.37 no.1
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    • pp.32-46
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    • 2021
  • South Korea has been divided into quantities and water quality, and due to a revision of the Government Organization law in June 2018, the controversial water management system was integrated into the Ministry of Environment. The total Maximum Daily Loads System has been called the flower of water quality control, and since 2004, all three major river systems which have been introduced into the Han River system, despite its various difficult environments, and subsequently leading to all of the four major rivers undergoing obligatory implementation since 2013. Currently, the target TMDL (Han River Phase 1 and Other Water Systems Phase 3) for the 2020 stage has been implemented. The domestic TMDL established a basic plan for calculating the load which complies with the unit watershed's target water quality, as well as an implementation plan for annual load management, both which have been institutionalized in order to evaluate load compliance on a repeated annual basis. Local governments ask external organizations to conduct investigations every year in order to assess the transition, which thereby requires tens of millions of won every year. Therefore, an assessment and management model that can be easily operated at the TMDL personnel level is required. In this study, when the Han river Water System TMDL was implemented in earnest, we confirmed the the water quality improvement effect when TMDL was introduced to major inflow tributaries (TancheonA, JungnangA, AnyangA) under the Seoul City's jurisdiction through the use of the total amount control unit basin evaluation technique. By presenting customized management measures, we propose the guidelines that are necessary for determining more effective water environmental policies.

Superhongmi bran extract improves lipid profile and menopause symptoms: a randomized, placebo-controlled clinical trial (슈퍼홍미 미강 추출물의 폐경 후 여성의 혈중 지질 농도 및 대사성 질환 개선 효과)

  • Chung, Soo Im;Nam, Su Jin;Liang, Jie;Ma, Jing Wen;Kang, Mi Young
    • Korean Journal of Food Science and Technology
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    • v.51 no.2
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    • pp.182-187
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    • 2019
  • Women who undergo natural menopause transition have increased numbers of risk factors relating to metabolic syndrome due to estrogen deficiency. This study was conducted to investigate the effect of Superhongmi bran extract on metabolic syndrome improvement in menopausal women. Thirty women, who participated in a randomized, double-blind, placebo-controlled trial, were assigned to placebo-control (n=15) or Superhongmi bran extract (n=15) groups and were asked to consume two tablets (350 mg per extract per tablet) per day. After 12 weeks, weight, body mass index (BMI), plasma triglyceride (TG) levels, and total cholesterol (TC) levels were significantly decreased, whereas HDL-cholesterol (HDL-C), apolipoprotein A1 (ApoA1), adiponectin, superoxide dismutase 1 (SOD1), and GSH (glutathione) concentrations were significantly increased in the Superhongmi bran extract group. Moreover, $17{\beta}-estradiol$, and progesterone levels in the Superhongmi group were significantly higher than those in the placebo-control group. These results suggest that Superhongmi bran extract alleviates metabolic symptom in menopausal women.