• Clinics in Orthopedic Surgery
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• 제10권4호
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• pp.455-461
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• 2018

Background: Surgical-site, multimodal drug injection has recently evolved to be a safe and useful method for multimodal pain management even in patients with musculoskeletal trauma. Methods: Fifty consecutive patients who underwent plating for mid-shaft and distal clavicular fractures were included in the study. To evaluate whether surgical-site injections (SIs) have pain management benefits, the patients were divided into two groups (SI and no-SI groups). The injection was administered between the deep and superficial tissues prior to wound closure. The mixture of anesthetics consisted of epinephrine hydrochloride (HCL), morphine sulfate, ropivacaine HCL, and normal saline. The visual analogue scale (VAS) pain scores were measured at 6-hour intervals until postoperative hour (POH) 72; stress biomarkers (dehydroepiandrosterone sulfate [DHEA-S], insulin, and fibrinogen) were measured preoperatively and at POH 24, 48, and 72. In patients who wanted further pain control or had a VAS pain score of 7 points until POH 72, 75 mg of intravenous tramadol was administered, and the intravenous tramadol requirements were also recorded. Other medications were not used for pain management. Results: The SI group showed significantly lower VAS pain scores until POH 24, except for POH 18. Tramadol requirement was significantly lower in the SI group until POH 24, except for POH 12 and 18. The mean DHEA-S level significantly decreased in the no-SI group ($74.2{\pm}47.0{\mu}g/dL$) at POH 72 compared to that in the SI group ($110.1{\pm}87.1{\mu}g/dL$; p = 0.046). There was no significant difference in the insulin and fibrinogen levels between the groups. The correlation values between all the biomarkers and VAS pain scores were not significantly different between the two groups (p > 0.05). Conclusions: After internal fixation of the clavicular fracture, the surgical-site, multimodal drug injection effectively relieved pain on the day of the surgery without any complications. Therefore, we believe that SI is a safe and effective method for pain management after internal fixation of a clavicular fracture.

• 품질경영학회지
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• 제50권3호
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• pp.373-386
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• 2022

Purpose: This study proposes the application of Six Sigma management innovation method for more systematically enhanced execution of Quality by Design (QbD) activities. QbD requires a deeper understanding of the product and process at the design and development stage of the drug, and it is very important to ensure that no fault is fundamentally generated through thorough process control. Methods: Analyzing the background and specific procedures of quality improvement based on the drug design basis, and analyzing the key contents of each step, we have differentated and common points from the 6 Sigma methodology. We propose a new model of Six Sigma management innovation method suitable for pharmaceutical industry. Results: Regulatory agencies are demanding results from statistical analysis as a scientific basis in developing medicines to treat human life through quality improvement activities based on drug design. By utilizing the education system to improve the statistical analysis capacity in the Six Sigma activities and operating the 6 Sigma Belt system in conjunction, it helped systematically strengthen the execution power of quality improvement activities based on pharmaceutical design based on the members of the pharmaceutical industry. Conclusion: By using QbD Six Sigma, which combines quality enhancement based on pharmaceutical design basis and Six Sigma methodology suitable for pharmaceutical industry, it is possible to obtain satisfactory results both by pharmaceutical companies and regulators by using appropriate statistical analysis methods for preparing scientific evidence data required by regulatory.

• 가족자원경영과 정책
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• 제21권4호
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• pp.1-15
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• 2017

The purpose of this study was to identify the effect of satisfaction with the marriage support policy on marriage intention among unmarried employed men and women. The study subjects included 300 unmarried working men and women aged over 30 years residing in the Seoul metropolitan area. First, according to the analysis of the subjects' overall tendency towards satisfaction with the marriage support policy and towards marriage intention, the marriage support policy gained the highest level of support in relation to housing for newlywed couples, which scored 3.29 (sd=.93), followed by improvements in corporate and family culture for the purposes of work-family compatibility at 3.24 (sd=.95), wedding loans at 3.18 (sd=1.01), and the paid leave system for marriage preparation at 3.12 (sd=.88). These variables scored slightly higher than the median 3 points. Conversely, satisfaction with the availability of marriage-related information and the provision of opportunities for dating scored 2.65 (sd=.88) and 2.78 (sd=.80), respectively, both of which were slightly lower than the median of 3. The overall mean score for satisfaction with the marriage support policy was 3.03 (sd=.95), which was slightly higher than the median of 3. In regards to marriage intention, the score was 3.32 (sd=1.15) points out of a perfect score of 5, which was slightly higher than the median. This indicated a slightly higher level in terms of the subjects' intention to marry. Second, a hierarchical regression analysis was performed to identify the effect of satisfaction with the marriage support policy on marriage intention among unmarried employed adults. Sociodemographic variables were entered as control variables in the regression at the first stage, and variables relating to satisfaction in a family-friendly social environment were entered at the second stage. When gender, age, educational level, monthly income, period of employment, working hours, and type of employment were inserted in the first stage of regression as control variables, gender, monthly income, period of employment, and type of employment were found to have a significant effect on marriage intention. Marriage intention was found to be greater in unmarried men with higher monthly incomes and longer periods spent working, and in unmarried working men and women engaged in tenured employment work. When variables relating to satisfaction with the marriage support policy were inserted in the second stage of regression, gender, monthly income, type of employment, and satisfaction with direct marriage support had significant effects on marriage intention. It was found that marriage intention was greater in unmarried men whose monthly income was higher, whose employment type was tenured work, and who showed greater satisfaction with direct marriage support.

• 디지털융복합연구
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• 제13권8호
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• pp.245-251
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• 2015

디지털 사이니지 시스템이 윈도우 OS에 장착 된 PC에서 작동 될 경우, 구현 가격이 매우 높다. 이러한 문제점을 해소하고자, 최신 스마트폰에 활용되는 ARM Coretex계열의 멀티코어 프로세서가 탑재된 안드로이드 OS 플랫폼 기반의 저전력 저가격의 디지털 사이니지 시스템과, 원격제어기술을 응용하여 어디서나 광고단말기를 원격제어하고 원격콘텐츠를 관리할 수 있는 융복합형 웹서버 기반의 원격 콘텐츠 관리용 서버프로그램을 개발하였다. 구현된 시스템은 디스플레이를 포함한 일체화된 디지털 사이니지 시스템으로, 저전력 모바일 플랫폼을 최적화한 하드웨어 인터페이스로 설계 구현되었고, 상황정보센서를 이용하여 조도, 온도, 날씨, GPS등의 주변상황 정보를 습득한 서비스 융합형 모델을 구현하는 구조로 설계 구현되었다. 또한 콘텐츠 자동생성 모듈은 컨텐츠 사용자에게 전용 저작 도구와 SMIL 기반의 자동으로 가동되도록 프레임 워크에 의해 규정된 컨텐츠를 제공하고, 사용자 정보 데이터베이스에 저장된 사용자 정보를 참조하여 사용자별 맞춤형 SMIL 컨텐츠를 생성해주는 융복합형 기능이 구현되었다. 개발된 디지털 사이니지 시스템은 기존 윈도우 OS 환경 대비 50% 이상의 소비전력 저감과 16포인트 멀티터치 기능을 구현하였고 상용화를 위한 기본 환경시험성능을 모두 만족하였다.

• 정보처리학회논문지C
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• 제15C권3호
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• pp.205-212
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• 2008

다수의 이종 센서 네트워크가 넓은 지역에 포설된 경우 각 센서 네트워크에서 수집된 데이터를 싱크 (sink)에서 게이트웨이 (GW)로 전송하기 위해 릴레이 포인트 (relay point: RP)들로 구성된 전달망이 이용된다. 전달망 내에서 RP의 위치는 전달망의 에너지 효율을 결정하는 중요한 요인이지만 전달망 내의 싱크의 수가 동적으로 변하고 특히 싱크가 이동하는 경우 이들의 경로를 미리 알지 못한다면 각 RP의 최적 위치를 전달망 포설시에 결정할 수 없게 된다. 이를 해결하기 위해 본 논문에서는 RP를 격자 모양으로 포설한 트리 기반 전달망에서 RP의 운용 비용과 경로 관리 부하 측면에서 효율적인 싱크와 GW 사이의 경로 관리 기법을 제안한다. 제안 기법의 성능은 단일 경로 설정 비용에 대한 수학적 분석과 ns-2를 이용한 모의 실험을 통해 검증되었다. 분석 결과 제안 기법은 싱크과 GW 사이의 데이터 전송 시간, 전달망의 서비스 지속 시간 및 경로 관리 부하 측면에서 AODV보다 우수하였다.

• 생물환경조절학회지
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• 제25권1호
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• pp.1-8
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• 2016

본 연구에서는 새만금 개발구역에서 환경조절 비용이 적게 들 수 있도록 기상환경을 분석하여 조성 적지를 선정하는 연구를 진행하였다. 작성된 10개의 주제도를 도면중첩하여 50~59점 지역을 적지로 도출하였다. 그 중 농업생명용지 계획지역을 중첩하여 최종적인 시설원예단지 조성 적지로 선정하였다. 본 연구는 시설원예의 환경조절 비용을 낮추어 부가가치를 상승 시킬 수 있다. 새만금에서 시설원예의 대규모를 통해 우리 농업의 국제 경쟁력 도움이 될 수 있다.

• 동아시아식생활학회지
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• 제24권6호
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• pp.862-874
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• 2014

Salt-fermented fish and fish sauce are very important materials to make Kimchi. They provide good taste and plenty of nutrition to Kimchi during fermentation. However, it is difficult to purchase Korean salt-fermented fish or fish sauce out of Korea. Therefore, to generalize Kimchi for other countries, this research carefully compared the quality differences between Kimchi made with South East Asian fish sauce, which is fairly similar to traditional Korean salt-fermented anchovy extract (Aekjeot) in terms of taste and ingredients, and that made with traditional Korean salt-fermented anchovy extract. To determine quality differences among traditional Korean Kimchies made with different sauces, Korean-made salt-fermented shrimp, salt-fermented shrimp extract, salt-fermented anchovy and salt-fermented anchovy extract were used. Of the four Kimchis, the one made with salt-fermented anchovy extract was chosen as a control sample and compared with those made with three different South-East Asian fish sauces. In the sensory evaluation for acceptance of fish sauces, characteristics of taste, texture and overall acceptance showed significant differences. In the sensory evaluation for differences, characteristics of fish odor and crunchiness showed visible differences. For umami taste, all fish sauces received higher points than Korean salt-fermented anchovy extract (control sample), although the difference was not significant. Sensory evaluation and research results show that Kimchi can become a highly likable food overseas and Kimchi can substitute easily bought South-East Asian fish sauces for Korean salt-fermented fish sauces (Jeotkal).

• 정보관리학회지
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• 제28권3호
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• pp.65-82
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• 2011

서지레코드의 기술에 있어서 책임표시는 저작의 지적 책임 소재를 밝혀 주고 접근점을 구성하는 바탕이 된다. 그런데 목록규칙에서는 책임표시를 주된 역할과 부차적 역할로 나누고, 이에 따라 기술방법을 달리 하는데 치중하는 문제점이 있다. 역할의 중요도를 판단하여 순서를 매기기보다는 역할 자체를 구조화시키는 것이 우선이기 때문이다. 또한 목록에서 주저자를 선정한 것은 책임성에 따른 것보다는 저록의 작성이나 배열과 관련된 실무적 결정이었다. 이에 본 연구에서는 역할 자체를 구조화함으로써 책임표시 기술방식을 개선하고자 하였다. 즉, 역할어를 체계적으로 기술하여 서지레코드에서 분산되거나 접근점에서 제외된 책임표시를 집중시키는 것이다. 나아가 이를 통해 책임표시 정보의 품질을 제고하고, 역할어를 검색의 패싯이나 전거레코드의 추가적인 식별 정보로도 활용할 수 있음을 제안하였다.

• 한국환경과학회지
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• 제19권1호
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• pp.39-45
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• 2010

When the Juam multipurpose dam which is connected with existing large water supply facilities is finished, water environment is changed from stream to lake. The changed quality of water should be examined. In this study, the result of water quality forecasting is analysed and an effective management plan of water quality is presented. Tn this study, the WASPS model that is a dynamic water quality simulation model was selected to forecast the water quality. This model forecasts movement of change of pollutants. For an application of the model, the subject areas were divided into seventeen sub-areas by considering change temperature depending measuring points and on depth of water. Meteorological data collected by the meteorological observatory and data about quality measured by the Korea Water Resources Development Corporation were used for an operation of the model. As a result of quality examination through quality data and estimated pollutant loading, the water quality environment criterion was grade II and the nutritive condition was measured as meso-graphic grade. In this study, an effective management was planned to improve water quality by reducing pollution load. According to the result of examination, when more than 30% of BOD was reduced it was recorded that the environment standard of water quality was improved to the second grade.

• Journal of Communications and Networks
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• 제10권4호
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• pp.455-464
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• 2008

To provide network services consistently under various network failures, enterprise networks increasingly utilize path diversity through multi-homing. As a result, multi-homed non-transit autonomous systems become to surpass single-homed networks in number. In this paper, we address an inevitable problem that occurs when networks with multiple entry points deploy firewalls in their borders. The majority of today's firewalls use stateful inspection that exploits connection state for fine-grained control. However, stateful inspection has a topological restriction such that outgoing and incoming traffic of a connection should pass through a single firewall to execute desired packet filtering operation. Multi-homed networking environments suffer from this restriction and BGP policies provide only coarse control over communication paths. Due to these features and the characteristics of datagram routing, there exists a real possibility of asymmetric routing. This mismatch between the exit and entry firewalls for a connection causes connection establishment failures. In this paper, we formulate this phenomenon into a state-sharing problem among multiple fire walls under asymmetric routing condition. To solve this problem, we propose a stateful inspection protocol that requires very low processing and messaging overhead. Our protocol consists of the following two phases: 1) Generation of a TCP SYN cookie marked with the firewall identification number upon a SYN packet arrival, and 2) state sharing triggered by a SYN/ACK packet arrival in the absence of the trail of its initial SYN packet. We demonstrate that our protocol is scalable, robust, and simple enough to be deployed for high speed networks. It also transparently works under any client-server configurations. Last but not least, we present experimental results through a prototype implementation.