• 한국임상수의학회지
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• 제21권1호
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• pp.62-65
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• 2004

A 13-year-old, male Maltese was refered to Veterinary Teaching Hospital of Konkuk University with inappropriate urination and hematuria. CBC, serum chemistry profile, urinalysis and urine culture were performed. Malignant cells were found in the urine sediment. Thoracic and abdominal radiography, retrograde positive-contrast cystography, retrograde double-contrast cystography, excretory urography, ultrasonography were performed. On the retrograde positive-contrast cystography examination, irregular filling defects were present on the left side of the cranial part of the bladder. Partial cystectomy performed and then medical therapy was conducted. On histopathological examinations, the lesion was confirmed as a transitional cell carcinoma of the urinary bladder.

• 한국방사선학회논문지
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• 제10권1호
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• pp.29-37
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• 2016

CT 조영검사 예약환자의 원활한 검사 진행과 조영검사로 인한 부작용을 줄일 수 있는 전처치 프로세스 시스템을 개발 및 적용하여 CT 조영검사 예약환자의 검사 만족도를 높이고자 하였다. 2014년 1월부터 2014년 2월까지 CT 조영검사를 예약하여 추적검사를 시행했던 2,846명의 환자들 중 예약시간에 검사를 시행하지 못하고 지연된 214명의 환자들을 대상으로 지연사유를 분석한 후 전처치 프로세스 시스템을 구상 및 개발하여 2015년 1월부터 2015년 2월까지 전처치 프로세스 시스템을 이용하여 전처치가 필요한 644명을 대상으로 SMS 전송 시행율, SMS 전송내역, 예약시간 준수율, 예약시간 지연 사유, 예약 시간보다 지연된 시간 등을 분석하였다. 2014년 1~2월 외래 CT 조영검사 예약환자는 2,846명이었고, 그 중 예약시간에 검사를 시행하지 못한 환자는 214건으로, 약 7.52%의 비중을 차지하고 있었다. 예약시간보다 지연된 세부적인 사례는 creatinine 미확인이 98건(46%), creatinine 1.3 이상이 40건(19%), 과거조영제부작용이 34건(16%), 금식 등 전처치 미흡이 25건(11%), 메트포민제제 당뇨약 복용이 4건(2%), 기타 이유가 13건(6%)으로 나타났으며, 평균 지연시간은 creatinine 미확인이 120분, creatinine 1.3이상이 30분, 과거조영제부작용이 40분, 금식 등 전처치 미흡이 120분, 메트포민제제 당뇨약 복용이 30분, 기타 사유가 60분으로 나타났다. 2015년 1월~2 월 전처치 프로세스 시스템을 적용하여 전처치가 필요한 대상자 644명중 SMS 전송시행율은 515건(80%)으로 나타났으며, SMS 전송내역을 분석한 결과 당일 검사가 283건(44%), 진료과 방문이 185건(29%), 전처치 불필요가 47건(7%), 외래과에서 전처치 프로세스 시스템 미확인으로 SMS 전송이 안 된 건수가 129(20%)건으로 나타났다. CT 조영검사 예약시간 준수율은 전체 644건 중 560건(87%)이 예약시간 안에 검사를 시행하였으며, 예약시간보다 지연된 세부적인 사례는 creatinine 미확인이 23건(28%), creatinine 1.3이상이 11건(13%), 과거조영제부작용이 7건(8%), 금식 등 전처치 미흡이 30건(36%), 메트포민제제 당뇨약 복용이 6건(7%), 기타 이유가 7건(8%) 이었다. 예약시간보다 평균 지연된 시간은 creatinine 미확인이 90분, creatinine 1.3이상이 20분, 과거조영제부작용이 30분, 금식 등 전처치 미흡이 120분, 메트포민제제 당뇨약 복용이 30분, 기타 사유가 60분으로 나타났다. 조영제 부작용의 효율적인 관리적 측면과 CT 조영검사 예약시간에 검사가 원활하게 진행될 수 있도록 전처치 프로세스 시스템을 적용해본 결과 적용 전에 비해 전처치 준비 시간이 줄어들고 CT실, 진료실, 채혈실, 주사처치실 등의 방문횟수 및 동선이 줄어들어 CT실을 찾는 고객들의 검사만족도와 의료서비스 향상에 기여가 될 것으로 사료된다.

• 한국콘텐츠학회논문지
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• 제19권11호
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• pp.445-450
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• 2019

본 연구는 자기공명영상 동적검사 시 자동주입기의 사용에 따라 조영제 역류로 인한 생리식염수의 오염 현상을 실험적으로 증명함으로써, 오염된 실린지 재사용 문제의 심각성을 인식시키고자 하였다. 연구방법은 조영제 주입 전 생리식염수와 주입 후 생리식염수를 각각 채취한 다음, T1 강조영상을 획득하여 신호강도를 측정하여 비교하였다. 생리식염수의 주입 후 신호강도가 주입 전에 비해 523.43% 통계적으로 높게 나타났다(p<0.05). 이는 조영제 주입에 따른 압력에 의해 조영제가 관을 통해 역류하여 압력이 낮은 반대쪽 생리식염수를 오염시킨 것으로 분석되었다. 결론적으로 조영제 주입 시 사용하는 실린지는 조영제 역류로 인해 교차오염이 발생하므로 정량적 분석을 위한 검사 시 동일한 환자의 검사라도 검사순서를 변경하거나 실린지를 교체하여 오류를 방지해야 한다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제12권1호
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• pp.202-209
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• 1990

A retrospective study of 498 patients (591 joints) who had diagnosed as having internal derangement of the temporomandibular joint by history, clinical examination, and arthrography were evaluated. 66 patients (70 joints) were diagnosed as having meniscus perforation between the joint compartments. In those patients with pain (11 joints : 15.7%), pain and crepitation (24 joints : 34.3%), pain, crepitation and LOM (31 joints : 44.3%), and painless crepitation with LOM (4 joints : 5.7%) complained clinically. All these patients who had perforation showed irregularity in outline of the contrast material, bone contour-contrast material gaps, flattening of cortical layer of articular eminence. On the 20 joints treated surgically, 17 joints were found to have meniscus perforation at the time of surgery which correlated with their pre-operative radiographic and clinical diagnosis. Three joints could not found perforation of meniscus. This study was designed to examine of the incidences of the meniscus perforation in the above patients and to assess the diagnostic accuracy of arthrography by comparing the results with the finding of direct examination at TMJ surgery.

• 한국임상수의학회지
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• 제21권2호
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• pp.177-180
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• 2004

Lower motor neuron signs of hind limbs, anus and bladder were identified by history taking and physical examination in the 6.8 year-old mongrel dog and 2.6 year-old Cocker spaniel. The Cocker spaniel, also showed gradual cranial migration of neurologic deficit including respiratory paralysis. On plain radiography and myelography, intervertebral disc extrusion between L2 and L3, the infiltration of contrast medium into the spinal cord and cord swelling were found in the mongrel dog, and infiltration of contrast medium like hollowness of cord parenchyma was observed in the Cocker spaniel. On the basis of clinical signs and radiographic findings, they were diagnosed tentatively as acute myelomalacia. The Cocker spaniel died of respiratory paralysis on the following day. Decompressive surgery was performed on the mongrel dog and the extensive necrosis and hemorrhage were found at surgery. It was euthanized with the owner's consent because of the perceived poor prognosis. Histopathologic examination after autopsy confirmed acute diffuse hemorrhagic myelomalacia with the swelling and the inflammation of axon, showing hemorrhagic changes in the white matter and the grey matter.

• 대한수의학회지
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• 제60권3호
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• pp.145-153
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• 2020

This study aimed to evaluate the effects of a bioabsorbable bone hemostatic agent comprising poly (ethylene glycol-propylene glycol) copolymers (PEG-PPG) on hemostasis and osteogenesis. Bilateral 3 mm diameter calvarial defects were created in 99 male Sprague-Dawley rats. The defects were filled with PEG-PPG or bone wax. The defects of control group were left unfilled. Virtual autopsy was performed to evaluate bioabsorption. The calvaria were subjected to x-ray microtomography (microCT) and histological examination. Bone volume fraction (BV/TV) and bone mineral density (BMD) were measured using microCT; furthermore, white blood cell count and histological examination were performed. After application of PEG-PPG and bone wax, immediate hemostasis was achieved. Autopsy revealed that PEG-PPG disappeared within 48 h at the application site; in contrast, bone wax remained until 12 weeks. The PEG-PPG and control groups showed significantly more osteogenesis than the bone wax group with respect to BV/TV and BMD at 3, 6, and 12 weeks (p < 0.05). Histology revealed that the bone wax group exhibited little bone formation with inflammation. In contrast, PEG-PPG and control groups showed significantly more qualitative osteogenesis than the bone wax group (p < 0.01). In conclusion, PEG-PPG showed immediate hemostasis and was absorbed to allow progressive osteogenesis.

• 대한방사선기술학회지:방사선기술과학
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• 제20권2호
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• pp.68-72
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• 1997

Small bowel series using methylcellulose are considered a better technique than using other contrast media considering a significant decrease of transit time of $BaSO_4$ and that of the necessary time for the examination. We investigated the mean transit time of $BaSO_4$, maximum luminal diamenter of small bowel, optical density and flocculation frequency after adminstratting 100 ml of 120% $BaSO_4$ to 20 pts), 150 ml of 70% $BaSO_4$ to 20 pts and 200 ml of $BaSO_4$ with 600 ml of mechylcellulose. It was shown that the technique using 150 ml of 70% $BaSO_4$ had the best result. When we apply a adequate amount of density(w/v%), dosage to pts for small bowel series using MC, we can decrease an examination time and have the better image due to double contrast. It is considered that a more study to lower the density of 70% $BaSO_4$ is necessary.

• 대한방사선기술학회지:방사선기술과학
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• 제44권4호
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• pp.295-300
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• 2021

This study aims to present new chest AP examination exposure conditions through a study on the effect on image quality and patient dose by applying high tube voltage and scatter ray post-processing software during chest AP examination in digital radiography equipment. This study was used a human body phantom and in the chest AP position, the dosimeter was placed horizontally at the thoracic spine 6. The experiment was conducted by dividing into a low tube voltage (70 kVp, 400 mA, 3.2 mAs) group and a high tube voltage (100 kVp, 400 mA, 1.2 mAs) group. The collimation size (14″× 17″) and the source to image receptor distance(110 cm) were same applied to both groups. Radiation dose was presented to dose area product and entrance surface dose. Image quality was compared and analyzed by comparing the difference between the signal-to-noise ratio and the contrast-to-noise ratio of the image according to the application of the scatter ray post-processing software under each condition. The average value of the entrance surface dose in the low and high tube voltage conditions was 93.04±0.45 µGy and 94.25±1.51 µGy, which was slightly higher in the high tube voltage condition, but the dose area product was 0.97±0.04 µGy and 0.93±0.01 µGy. There was a statistically significant difference in the group mean value(p<0.01). In terms of image quality, the values of the signal-to-noise ratio and the contrast noise ratio were higher in the high tube voltage than in the low tube voltage, and decreased when the scattering line post-processing function was used, but the contrast resolution was improved. If there is a scatter ray post-processing function during chest AP examination, it is helpful to actively utilize it to improve the image quality. However, when this function is not available, I thought that applying a higher tube voltage state than a low tube voltage state will help to realize images with a large amount of information without changing the dose.

• 핵의학기술
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• 제16권2호
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• pp.57-61
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• 2012

전신 뼈 검사에 이용되는 방사성의약품의 주된 집적부위는 뼈 무기질이며 그 섭취기전은 명백히 밝혀져 있지 않다. 전신 뼈 검사에서 일시적으로 미만성 간 섭취가 나타날 수 있으며, 간내 섭취의 원인은 다양하게 보고되고 있다. 본 연구에서는 전신 뼈 검사에서 $^{99m}Tc$-DPD의 미만성 간 섭취에 MRI 조영제가 미치는 영향을 알아보았다. 2010년 1월부터 12월 사이에 $^{99m}Tc$-DPD 전신 뼈 검사를 시행한 환자 중 982명을 연구의 대상으로 하였다. 982명의 환자는 전신 뼈 검사 이전에 MRI 조영제를 사용한 검사를 시행하였다. 혈액학검사 및 일반화학검사 소견을 조사한 결과 전신 뼈 검사에서 46명의 환자(남:여=39:7)가 미만성 간 섭취를 보였다. 추적 전신 뼈 검사를 시행하였으며, 이전에 보였던 미만성 간 섭취는 모두 소실되어 정상적인 소견을 보였다. 간기능 및 신기능 검사는 모두 정상이었다. 전신 뼈 검사에서 $^{99m}Tc$-DPD의 미만성 간 섭취에 MRI 조영제가 간접적인 영향을 주고 있다. $^{99m}Tc$-DPD의 미만성 간 섭취를 피하기 위해서 전신 뼈 검사는 MRI 조영제를 사용한 검사를 시행하기에 앞서서 먼저 시행하여야 하고, MRI 조영제를 사용한 검사가 있을 경우에는 조영제가 몸에서 제거된 후 검사를 시행하여야 할 것이다.

• Nuclear Medicine and Molecular Imaging
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• 제40권3호
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• pp.186-187
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• 2006

A 64-year-old female with glioblastoma multiforme (GBM) was assigned to our department for whole body PET/CT scan. She ingested 1 liter of pure water as negative oral contrast just before PET/CT examination. FDG-PET/CT images showed a very intense hypermetabolic, focal lesion in the abdominal cavity around descending colon. The SUVmax of the lesion was 17.2. But there was no abnormal lesion corresponded to the area of PET scan in the combined contrast enhanced CT scan. We suggested considering a malignant lesion due to very intense glycolytic activity. Conventional abdominal CT scan & colonoscopy were accomplished within one week after PET/CT evaluation. There was no abnormality in both examinations. We executed follow-up PET/CT evaluation after 1 month and couldn't find any abnormality around the corresponding area. So we concluded the hypermetabolism was colonic physiologic uptake. A colonic physiologic uptake is a well known cause of false positive finding. Nuclear physicians should be considered the possibility of malignancy when interpret focal colonic uptake, especially incidental finding. There are a few reports that using of negative oral contrast is able to reduce gastrointestinal physiologic uptakes. But as we can see in this case, although we used negative oral contrast, intense physiologic uptake is detected and maxSUV is able to up to 17.2. So, it is important to keep a fact in mind. Even though there is a colonic physiologic uptake in PET/CT image, it may be able to show very intense hypermetabolism regardless of using negative oral contrast.