• The Korean Journal of Oral and Maxillofacial Pathology
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• v.42 no.5
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• pp.111-118
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• 2018

Nicotine of tobacco component has a controversial impact in the clinical outcome of dental implants. Although numerous nicotine effects on bone healing around implants have been presented, it is rarely reported in vitro study about normal human osteoblast(NHost) from oral and maxillofacial area at the surface of implants. The purpose of the present study was to evaluate the effect of nicotine on the proliferation and differentiation response of NHost to plasmatic and salivary levels of nicotine reported in smokers at the surface of screw-type plasma-sprayed titanium implants. NHosts were seeded on the surface of titanium implants and cultured for 21 days in ${\alpha}-MEM$ supplemented with 10% FBS, 50mg/ml ascorbic acid, 5mM ${\beta}$-glycerophosphate and 100nM dexamethasone. Seeded implants were exposed to various nicotine concentration(0.05-0.5mg/ml) from 1 to 21 days, and characterized for cell morphology, proliferation, differentiation, alkaline phosphatase(ALP) activity and ionized calcium concentration(Cai) of medium. Continuous exposure to higher nicotine concentration(above 0.3mg/ml) induced a dose- and time-dependent vacuolation of the cytoplasm, and a tendency to detach from the implant surface. 0.05mg/ml(lower nicotine concentration) did not cause significant effects in the cell proliferation and ALP activity. 0.1-0.2mg/ml caused evident dose-dependent effects in increased cell proliferation, ALP activity and earlier onset of matrix mineralization at levels up to 0.2mg/ml, while a dose-dependent inhibitory effect at 0.3-0.5mg/ml. Cai concentration of control group was decreased at 14 days. Increased Cai concentration at 0.1-0.2mg/ml, decreased Cai concentration at 0.3mg/ml and no change at 0.5mg/ml during the culture period were seen. It suggested that nicotine concentration could paly an role in modulating NHost activity as a contributing factor associated with proliferation and differentiation of NHost at the surface of implants.

• Journal of the Korean Geotechnical Society
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• v.35 no.3
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• pp.17-24
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• 2019

The purpose of this study is to understand the characteristics of bearing capacity of shallow foundation on the grounds. We made a comparative study of existing bearing capacity theory, based on the three-dimensional finite element analysis with a variety of conditions such as ground condition, foundation scale and foundation shape. In the finite element analysis, the ultimate bearing capacity showed a gradual convergence in the form of exponential function or logarithm function according to the foundation scale. Although the shear strength increased, the bearing capacity tended not to increase but change linearly. In the results of comparative study of existing bearing capacity theory, bearing capacity ratio ($q_{u(FEA)}/q_{u(theory)}$) of pure sand has the outcome closest to those of the Terzaghi method. Pure clay turned out to be about 0.4~0.6 while normal soil was changed in a range of 0.3~1.3. As shear strength is increased, the results turned out to be less than 1.0. Bearing capacity ratio ($q_u/q_{u(1.0)}$), normalized at 1.0m bearing capacity, was about 35%, 15% and 5% of theoretical formula under the condition of ${\phi}=25^{\circ}$, $30^{\circ}$ and $35^{\circ}$ of pure sand; no scale effect was found with pure clay and the normal soil with lower soil strength level showed less than 10% of the theoretical formula of pure sand. Bearing capacity ratio of each case, in accordance with, the shear strength increase, was largely influenced by the internal friction angle. Shape factor of bearing capacity ratios classified by foundation shapes have different results according to the shapes; the shape factor of circular foundation is 1.50, square foundation is 1.30, rectangular and continuous foundations are 1.1~1.0.

• The Journal of Internal Korean Medicine
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• v.43 no.4
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• pp.542-558
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• 2022

Objectives: The purpose of this study was to assess the effect of Yigong-san on anorexia in children by conducting a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: Eleven electronic databases were searched on May 30, 2022 to collect relevant studies. All studies published up to the search date were considered. RCTs reporting the effect of Yigong-san on the treatment of anorexia in children were included. The primary outcome was an improvement in clinical anorexia symptoms after treatment. In this meta-analysis, continuous and binary outcomes were assessed, and the data were presented as the mean difference and risk ratio with their 95% confidence intervals. The risk of bias was assessed using the Cochrane Collaboration's risk of bias tool. Results: A total of nine studies were included in this systematic review. The treatment group (Yigong-san only or Yigong-san plus conventional treatment) showed a statistically significant effect compared to the control group (conventional treatment only) in total effective rate (Yigong-san only: RR 1.26, 95% CI 1.17, 1.36, I²=0%; Yigong-san plus conventional treatment: RR 1.32, 95% CI 1.18, 1.47, I²=0%), clinical symptoms, some of the anthropometric outcomes, and biological markers related to appetite and growth in children with anorexia. No serious adverse events related to Yigong-san were reported. Conclusions: Yigong-san showed statistically significant effects as a treatment for anorexia in children. However, the number of studies included in the meta-analysis was insufficient, and the herbs contained in the Yigong-san used in the included studies were not standardized. Future research should focus on the implementation of methodologically robust clinical research.

• Journal of Korea Entertainment Industry Association
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• v.14 no.5
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• pp.255-266
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• 2020

This study conducted a systematic literature review on nursing students to find out the types and composition of patient safety-related education programs. The research was conducted systematically using PRISMA. The patient was a nursing college student, and the intervention was patient safety education. The outcome was either numerical or descriptive reports of the results measured using the tool. The types of research were carried out including randomized design, quasi-experimental design, one-group design, survey and qualitative research. The paper was searched through Medline, Embases, CINAHL, DBpia, Riss and KISS. A total of 2,468 papers were searched in the search results, and nine papers were used for analysis as a result of extracting data according to PICO. The characteristics of patient safety education of nursing college students were classified according to the teaching method, period, result variables and measurement tools. As a result, patient safety education consisted of a variety of subjects, and was being taught through lectures, clinical practice, laboratories, and simulations. The period of education also varied. The resulting variables were mainly checked for knowledge, attitude, and skill, and the tools used to measure them varied. Patient safety education for nursing college students was conducted through various topics, methods and periods at home and abroad. Therefore, continuous research is needed to establish consistent and integrated patient safety education in educational institutions and working institutions to produce nursing personnel with patient safety capabilities.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1247-1248
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• 2022

Due to rapid urbanization and population growth, it has become crucial to analyze the various volumes and characteristics of pedestrian pathways to understand the capacity and level of service (LOS) for pathways to promote a better walking environment. Different indicators have been developed to measure pedestrian volume. The pedestrian level of service (PLOS), tailored to analyze pedestrian pathways based on the concept of the LOS in transportation in the Highway Capacity Manual, has been widely used. PLOS is a measurement concept used to assess the quality of pedestrian facilities, from grade A (best condition) to grade F (worst condition), based on the flow rate, average speed, occupied space, and other parameters. Since the original PLOS approach has been criticized for producing idealistic results, several modified versions of PLOS have also been developed. One of these modified versions is perceived PLOS, which measures the LOS for pathways by considering pedestrians' awareness levels. However, this method relies on survey-based measurements, making it difficult to continuously deploy the technique to all the pathways. To measure PLOS more quantitatively and continuously, researchers have adopted computer vision technologies to automatically assess pedestrian flows and PLOS from CCTV videos. However, there are drawbacks even with this method because CCTVs cannot be installed everywhere, e.g., in alleyways. Recently, a technique to monitor bio-signals, such as electrodermal activity (EDA), through wearable sensors that can measure physiological responses to external stimuli (e.g., when another pedestrian passes), has gained popularity. It has the potential to continuously measure perceived PLOS. In their previous experiment, the authors of this study found that there were many significant EDA responses in crowded places when other pedestrians acting as external stimuli passed by. Therefore, we hypothesized that the EDA responses would be significantly higher in places where relatively more dynamic objects pass, i.e., in crowded areas with low PLOS levels (e.g., level F). To this end, the authors conducted an experiment to confirm the validity of EDA in inferring the perceived PLOS. The EDA of the subjects was measured and analyzed while watching both the real-world and virtually created videos with different pedestrian volumes in a laboratory environment. The results showed the possibility of inferring the amount of pedestrian volume on the pathways by measuring the physiological reactions of pedestrians. Through further validation, the research outcome is expected to be used for EDA-based continuous measurement of perceived PLOS at the alley level, which will facilitate modifying the existing walking environments, e.g., constructing pathways with appropriate effective width based on pedestrian volume. Future research will examine the validity of the integrated use of EDA and acceleration signals to increase the accuracy of inferring the perceived PLOS by capturing both physiological and behavioral reactions when walking in a crowded area.

• Journal of Venture Innovation
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• v.6 no.4
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• pp.83-97
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• 2023

The growth of the live commerce market allows you to conveniently and simply start live commerce anytime, anywhere with a smartphone. The use of smartphone services provides continuous communication and is used while feeling psychological attachment, and it leads to psychological attachment, self-consistency with consumers themselves, and self-identity. This study focuses on the motives and perceptions of consumers using live commerce. In other words, we will examine the relationship with service attachment through the moderating effect of self-efficacy and control focus tendency as consumers' personal and psychological characteristics. In other words, the tendency of regulatory focus, which determines the direction of behavior of consumers according to their motives and goals, affects the service attachment of live commerce. We believe that self-efficacy, which is personal confidence and belief that you can plan and execute on your own for the desired outcome in a given situation or task, will control this relationship. As a result of this research, consumers who highly perceive prevention focus were more likely to avoid negative consequences and pursue safety and obligations. Their attachment to live commerce services was stronger, offsetting their confidence and self-efficacy. When using live commerce services, the more they perceive that information acquisition is beneficial, the higher their belief, and self-efficacy, so service attachment, which is an emotional experience as well as a cognitive experience, is strongly formed for consumers with a preventive focus to avoid safety-seeking and negative consequences. Through the present research results, we believe that it will be helpful in operating strategies and management for companies and small business owners who want to understand the psychological behavior of consumers in using live commerce services.

• Management & Information Systems Review
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• v.36 no.1
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• pp.115-141
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• 2017

This study is to find the key factors of the Internet of Things for development in public sector. In previous studies, it is said that Internet of Things can work digital system without human operation and gives a lot of outputs(information) users. Generally, people are a subject of operating digital system in traditional way, while people are an object on the internet of things. In other words, it is possible to work digital system with only networking from things to things. After all, it is reported that these advantages of the Internet of Things make possible to reduce social costs significantly in public sector. However, despite the strengths of the Internet of Things, there is a specific user acceptance of the technology factor for the Internet of Things rarely. It means that developing of the Internet of Things only focuses on the final purpose. If the focus on development meet this purpose, the user is ignored for the specific reason that using a technique. As a result of this, many users gradually decrease the continuous using of the Internet of Things. Thus, in this study, we need to find what critical factors should reflect to the Internet of Things in public sector. To find this result, there is no choice to use Technology Acceptance Model(TAM). Many researchers have proved that Technology Acceptance Model is valid through the four process in model introduction, confirmation, expansion and refinement from 1986 to 2003. The results of this study showed that the result explanatory power of Internet of Things in public sector is the most important factor affecting only perceived social usefulness and ease of use. Finally, it can be seen that the user has a positive attitude toward use, which has a positive effect on the intention to use continuously. The implications of this study are summarized as follows: When the public Internet of Things service is provided, it means that the user can easily understand the result, and when the person and the object communicate the result to each other, they should be able to communicate with each other. This means that a lot of user effort is needed to understand the outcome of the public Internet of Things being provided.

• The Journal of Industrial Distribution & Business
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• v.1 no.1
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• pp.5-12
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• 2010

The retail business of drugstore was introduced to Korea for the first time 10 years ago. Since Olive Young introduced a retail store in the name of drugstore in 1999 for the first time in Korea, new distribution channel combining drugstore, cosmetic products and dairy products, etc has been made. At initial stage, the new distribution channel grew up slowly because of low specialty and economic stagnation. However, the three big distribution channels, that is to say, Olive Young (CJ), Watsons (GS) and W Store (Kolon Well Care), etc, were established to produce new distribution system following large-scaled discount stores as well as convenience stores. The purpose of the study is to investigate ways making Korean style drugstore be new retail business in addition to traditional markets, department stores, E-Mart and other general super markets and to examine problems preventing the drugstore from being promoted and to find out solutions. The speciality retailers that is called a category killer attacking department stores as well as marts is expanding market quickly. New consumption trend that gives priority to wellbeing is being expanded in accordance with high level of standards of living life: The drugstore is thought to be new alternative of distribution because it keeps special products. Young ladies who are main customers of drugstores respond to the trend sensitively to have more buying power that is thought to be promising. And, consumers' desire has become concrete and special. This is because consumers want not only convenient shopping but also special shopping system that is current trend. These days, so called Multi-shop and Total shop and other special shops have been recently opened. Special multi-shop has been concentrated on fashion product and miscellaneous goods so far: Health total wellbeing shop shall be popular in accordance with wellbeing trends. Drugstores can play an important role. Drugstores were opened for the first time ten years ago. In particular, Olive Young succeeded in going into the black after making efforts for a long time by many persons. Drugstores could succeed in the business owing to many persons in the past as well as customers who liked drugstores. However, drugstores once lost ways and recorded poor business results. The three drugstores, that is to say, Olive Young, Watsons making efforts to go into the black and W-Store pursuing traditional drugstore shall compete each other and make effort to satisfy customers' desire. In that way, the three drugstores can be assured of present business as well as future business. The consumers' demand trend has become special at sub-division so that drugstores that can satisfy the demand can succeed in the business. Large businesses may be more interested in the 4th generation retail business to produce good income and to have bright future. Drugstore business and market are likely to expand and develop owing to large business' participation in drugstore business. Drugstores expanded shop at Seoul and Gyeonggi-do until middle of 2000. Drugstore business at station sphere in Seoul and Gyeonggi-do that have high ratio of temporary population has low customer loyalty to have limitation on continuous growth. Since 2009, drugstores have opened new shops at local towns: From the year of 2010, drugstores need to establish multiple shop strategy by accelerating business speed and to allow customers to drop in the shop anywhere in the nation and to enter consumers' life deeply, so that they can strengthen business base definitely. Drugstores need to have price competitiveness to have multiple shop opening strategy and to satisfy consumers and to supply high quality services that is future subject to solve. And, Olive Young and Watsons that are Korean style drugstore need to keep system in order and to strengthen substance as Korean style drugstore and to expand marketing, so that they can get business outcome within 5 years that was done 10 years before and they become the 4th generation retail business. The study had difficulties at collecting material from the three drugstore because of poor cooperation. And, the author had great difficulty at collecting statistical material that was made in disorder. Further effort is needed considering such problems.

• Journal of National Security and Military Science
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• s.9
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• pp.313-340
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• 2011

The National Defense Reformation bill of "National Defense Reformation 2020" which have been constantly disputed and reformed by the government went through various levels of complementary measures after the North Korean sinking on the Republic of Korea (ROK) Naval Vessel "Cheonan". The final outcome of this reform is also known as the 307 Plan and this was announced on the 8th March. The reformed National Defense Reformation is to reduce the number of units and military personnel under the military structure reformation. However, in order for us to undertake successful National Defense Reformation, the use of privatized civilian resources are essential. Therefore according to this theory, the ROK Ministry of National Defense (MND) have selected the usage of privatized resources as one of the main core agenda for the National Defense Reformation management procedures, and under this agenda the MND plans to further expand the usage of private Especially the MND plans to minimize the personnel resources applied in non-combat areas and in turn use these supplemented personnel with optimization. In order to do this, the MND have initiated necessary appropriate analysis over the whole national defense section by understanding various projects and acquisition requests required by each militaries and civilian research institutions. However for efficient management of privatized civilian resources, first of all, those possible efficient private resources which can achieve optimization will need to be identified, and secondly continuous systematic reinforcements will need to be made in private resource usage legislations. Furthermore, we would need to consider the possibility of labor disputes because of privatization expansion. Therefore, full legal and systematic complementary measures are required in all possible issue arising areas which can affect the combat readiness posture. There is another problem of huge increase in operational expenses as reduction of standby forces are only reducing the number of soldiers and filling these numbers with more cost expensive commissioned officers. However, to overcome this problem, we would need to reduce the number of positions available for active officers and fill these positions with military reserve personnel who previously had working experiences with the related positions (thereby guaranteeing active officers re-employment after completing active service). This would in tum maintain the standards of combat readiness posture and reduce necessary financial budgets which may newly arise. The area of maintenance, supply, transportation, training & education duties which are highly efficient when using privatized resources, will need to be transformed from military management based to civilian management based system. For maintenance, this can be processed by integrating National Maintenance Support System. In order for us to undertake this procedure, we would need to develop maintenance units which are possible to be privatized and this will in turn reduce the military personnel executing job duties, improve service quality and prevent duplicate investments etc. For supply area, we will need to establish Integrated Military Logistics Center in-connection with national and civilian logistics system. This will in turn reduce the logistics time frame as well as required personnel and equipments. In terms of transportation, we will need to further expand the renting and leasing system. This will need to be executed by integrating the National Defense Transportation Information System which will in turn reduce the required personnel and financial budgets. Finally for training and education, retired military personnel can be employed as training instructors and at the military academy, further expansion in the number of civilian professors can be employed in-connection with National Defense Reformation. In other words, more active privatized civilian resources will need to be managed and used for National Defense Reformation.

• Neonatal Medicine
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• v.17 no.2
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• pp.239-244
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• 2010

Purpose: To evaluate two different heel lancet device in terms of pain response and success of the procedure in the preterm infants undergoing heel puncture. Methods: 100 preterm infants undergoing capillary blood gas analysis or capillary bilirubin monitoring underwent heel puncture, were randomly allocated to blood sampling from the heel with either a conventional manual lancet or an automatic incision device. Primary outcome measures included the Premature Infants Pain Profile (PIPP) score, total duration of procedure, number of heel puncture and number of bruise. The pain response was evaluated using PIPP score and the effectiveness was evaluated using three criteria: total duration of blood sampling, number of puncture, bruising of the heel or ankle. Statistical analysis was performed using the SPSS ver. 13.0 program. Difference between the groups were analysed with t test (continuous variables) and the Chi square test or Fisher test (categorical variables). Results: The mean PIPP score was 4.91 for the automatic lancet group compared with 5.84 for the conventional manual lancet group (P=0.0255).The number of pain scores above 7 during blood collection did not differ between two groups (P=0.2167). The procedure took less time to perform in the automatic lancet group (mean, 30.69 seconds) than in the conventional lancet group (mean, 48.92 seconds) (P<0.0001). Conclusion: This study demonstrated that the automatic lancet device causes less pain and a shorter procedure time than the conventional manual lancet in preterm infants undergoing heel puncture. On the basis of these results the automatic lancet device is very useful method for blood collection in preterm infants by heel puncture.