The effect of vitamin E supplementation on plasma ${\alpha}$-tocopherol level, total antioxidant level and reproductive performance in Murrah buffaloes was studied during periparturient period. Twenty-four advance pregnant buffaloes were randomly divided into four equal groups as $T_1$, $T_2$, $T_3$ and $T_4$ and were supplemented with 0, 1,000, 1,500 and 2,000 IU of ${\alpha}$-tocopheryl acetate (Merck) from 60 days prepartum to 30 days postpartum and 0, 500, 750 and 1,000 IU from 30 to 60 days postpartum, respectively. Blood samples were collected at -60, -45, -30, -15, -7, 0, 7, 15, 30 and 60 days of parturition and were analyzed for plasma ${\alpha}$-tocopherol and total antioxidant activity (TAA). The intake of DM, CP and TDN did not vary among different groups. Plasma ${\alpha}$-tocopherol and TAA around parturition (-7 to 15 day) in $T_3$ and $T_4$ were significantly higher than the control group. There was 17% reduction in retention of fetal membranes (RFM) and metritis in $T_4$ than control. The post partum estrus interval averaged 58.00, 55.33, 51.83 and 43.00 days in $T_1$, $T_2$, $T_3$ and $T_4$ respectively. There was significant reduction in days open in both $T_3$ and $T_4$ in comparison to $T_1$ group (127,130 Vs.146). All the vitamin E supplemented groups showed reduction in days open than their previous lactation performance. Supplementation of vitamin E at $1,500IU\;d^{-1}$ from 60 day prepartum to 30 day post partum to buffaloes exhibited beneficial effect on plasma ${\alpha}$-tocopherol level and TAA around parturition and continuation of its supplementation at $1,000IU\;d^{-1}$ from 30 to 60 days of lactation improved post partum reproductive performance of buffaloes.
Journal of the Korean Society of Clothing and Textiles
/
v.34
no.9
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pp.1454-1469
/
2010
Brands have their own life cycles and exert a great influence on the marketing activities of companies. This study examines the marketing activities according to a brand life cycle and measures the scope of their performances. The research divides a fashion brand life cycle into three stages through the analysis of secondary data, and validates the causal relationship between marketing activities, brand equity, and consumer behavior according to the brand life cycle. A total of 573 responses were analyzed through a factor analysis, path analysis, and paired t-test with SPSS 12.0. The results are as follows: According to the analysis of the relationship between marketing mix and brand equity, distribution strategies are effective at the introduction/growth stage and the continuation stage. Advertisement strategies should be a main focus at the maturity stage for brand awareness. Throughout all the stages, product strategies wield the greatest influence on the brand image. Among brand equity components, the brand image has an influence on consumer behavior at every stage of the cycle while the brand awareness has no significant effect on consumer behavior. The marketing mix component that has the greatest impact on consumer behavior is product. Contrary to general expectations, price has a negative or insignificant effect on consumer behavior at every stage of the cycle. The results illustrated in this study help to understand the life cycle of fashion brands and characteristics different from consumer goods. Thus, fashion companies should identify at which stage their brands are positioned and develop different strategies to fit each stage.
Journal of the Korean Applied Science and Technology
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v.41
no.3
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pp.795-812
/
2024
The purpose of this study is to analyze the impact of online education characteristics on education satisfaction and intention to continue education, and to analyze the mediating effect of education satisfaction in the relationship between online education characteristics and education continuation intention. This study targeted adult women who experienced online skincare education and conducted a survey from March 1 to April 30. First, convenience, reliability, learner understanding, promptness of feedback, expertise, and attractiveness had a significant positive (+) effect on educational satisfaction. Second, educational satisfaction was found to have a significant positive (+) influence on the intention to continue education. Third, convenience, promptness of feedback, expertise, and attractiveness had a significant positive (+) effect on the intention to continue education, but learners' understanding appeared to have a negative (-) effect.Lastly, the mediating effect of education satisfaction was found to be significant in the relationship between education quality, instructor quality, and intention to continue education.
Road safety audit is the preventive enhancement strategy for safety. : it gets rid of beforehand the potential factor of a traffic accident in the stage of road planning and design and it evaluates the appropriation for road geometric structure or safety facility to prevent traffic accident in the stage of operation after the construction. Since this strategy is introduced to our country in the early 2000s, various projects have been processed and it was legislated recently. And now, the evaluation of past project for its continuation is needed. Therefore, in this study the evaluation of road safety audit on existing freeway is performed. The spatial extent of this study is Yong-dong line on which the safety treatment was executed in 2005 and 2006. And, the temporal range of this study is each 2-year of before and after from 2005 and 2006. The empirical bayes method of observational evaluation studies is applied to analyze. As a result, there is an effect of improvement on most of treated sections. But there is ineffective or negligible on some sections. Compared with the detail of treatment on each section, the effect of multiple or various treatments is good for that section. On the other hand, the section on which effect doesn't appear is the result of single or unimportant treatments. Throughout these results, the concrete analysis can be performed and the countermeasures designed for the section on which effect doesn't appear. Also it is used as reference to the future plan and direction of road safety audit on existing freeway.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
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v.46
no.1
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pp.78-83
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2020
Objectives: The discontinuation of bisphosphonate (BP) treatment before tooth extraction may induce medication-related osteonecrosis of the jaw (MRONJ). Whether the long-term discontinuation of BP treatment before tooth extraction affects the risk of developing MRONJ after tooth extraction or whether extended drug holidays induce systemic side effects remains unclear. The present study assessed the incidence of MRONJ among patients who underwent tooth extraction and did not discontinue BP therapy prior to the procedure. Materials and Methods: Patients were classified according to whether or not they discontinued BP therapy before tooth extraction. Differences in the incidence of MRONJ after tooth extraction were compared between the two groups using the chi-squared test. Results: The BP-continuation (BPC) and BP-discontinuation (BPDC) groups included 179 and 286 patients, respectively. One patient in the BPC group and no patients in the BPDC group developed MRONJ (P=0.385). The patients in the BPDC group stopped receiving BP therapy at a mean of 39.0±35.5 months prior to tooth extraction. Conclusion: The possibility of pre-existing MRONJ in the extraction area must be considered during the extraction procedure. Routine discontinuation of BP medications for several months before the extraction procedure should be carefully considered, as evidence of its efficacy in reducing the development of post-extraction MRONJ is limited.
There have been tremendous needs and requirements of special education for the gifted to the level of country development and for developing their talents. Even though a lot of research has been done on special education for the gifted supported by the government, lack of educational materials and material development has been a main concern. Some trails using the web with the help of information technology have been made on distance education and resulted good effect on education. No application using a web-based educational method has been made on special education for the gifted so far. This paper describes about the web-based special education for the gifted on mathematics. The discussed topics are development of educational materials, compliments of the current educational materials in mathematics being used at the KIGES(Kyungnam Institute of the Gifted Education in Science), and the continuation of special education for the gifted. Furthermore, a better and more efficient way is suggested for special education for the gifted that has been limited by geographic and locational restrictions.
Journal of Korea Technical Association of The Pulp and Paper Industry
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v.32
no.2
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pp.8-15
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2000
This study is a continuation of the previous experimental analysis and is mostly focused on handsheet strength properties. Four completely different fibers, which were Hw-BKP, SW-BKP, White ledger, and OCC, were selected to investigate the effect of mechanical pre-treatment by Hobart mixer on handsheet strehgth properties. After equal time mechanical pre-treatment, the fibers were refined with laboratory valley beater for 10, 20 and 30 minutes, and handsheets were prepared from the fibers for physical strength comparison. Handsheets from SW-BKP and OCC showed 5-30% increase of breaking length, burst index, tear index, and compression index while handsheets from HW-BKP and White ledger no increase except tear index. In Hobart mixer pre-treatment, HW-BKP and White ledger fibers were easily attached to the wall of the mixer bowl and mechanical action was not effectively applied. The fiber length of Hw-BKP and White ledger were 0.837 mm and 1.591 mm, respectively, while SW-BKP and OCC were 2.744 mm and 2.033 mm, respectively, in weight weighted length. The effective mechanical pre-treatment seems to be related to the fiber length. Tear indexes of the pre-treated furnish were much higher than no pre-treatment at the same breaking length level.
Background: It has been demonstrated that the expression of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and apoptotic cell death in the dorsal root ganglion (DRG) following spinal nerve constriction injury play a role in the initiation and continuation of hyperalgesia and allodynia. The present study was designed to investigate the effects of ethyl pyruvate (EP) on mechanical and cold allodynia, TNF-${\alpha}$ expression, and apoptosis in DRG after spinal nerve ligation injury. Methods: Rats were divided into 3 groups: control, pre-EP, and post-EP. EP (50 mg/kg) was intraperitoneally injected 30 minutes before (pre-EP) or after (post-EP) surgery. Behavioral tests to determine mechanical and cold allodynia were conducted before surgery and 4 and 7 days after surgery. Seven days after surgery, TNF-${\alpha}$ protein levels in DRG were evaluated by enzyme-linked immunosorbent assay, and DRG apoptosis was determined by immunohistochemical detection of activated caspase-3. Results: Treatment with EP significantly reduced mechanical and cold allodynia following spinal nerve ligation injury. TNF-${\alpha}$ protein levels in the pre-EP ($4.7{\pm}1.2$ pg/200 ${\mu}g$; P < 0.001) and post-EP ($6.4{\pm}1.8$ pg/200 ${\mu}g$; P < 0.001) groups were 2-3 times lower than the control group ($14.4{\pm}1.2$ pg/200 ${\mu}g$). The percentages of neurons and satellite cells that co-localized with caspase-3 were also significantly lower in the pre-EP and post-EP groups than the control group. Conclusions: These results demonstrate that EP has a strong anti-allodynic effect that acts through the inhibition of TNF-${\alpha}$ expression and apoptosis in DRG after spinal nerve ligation injury.
Purpose: This study examined the effects of breastfeeding education among preterm mothers. Methods: A nonequivalent control group, repeated measure, quasi-experimental study design was used. The participants comprised 46 preterm mothers recruited from the neonatal intensive care unit of a university hospital who were divided into two groups: 23 in the control group and 22 in the experimental group. The breastfeeding education program intervention to promote preterm mothers' self-efficacy used was devised based on the self-efficacy theory. The intervention program consisted of individual breastfeeding education with demonstrations and discharge education, and telephone follow-up education within one week after being discharged. The participants were surveyed before and after the intervention, and four weeks after being discharged from the newborn intensive care unit. Results: The intervention group showed a significant increase in breastfeeding self-efficacy compared with the control group (F=6.92, p=.003) and showed a significant increase in their breastfeeding attitude score (F=3.49, p=.039). Four weeks after discharge, the breastmilk volume of the intervention group increased significantly (t=-2.87, p=.006), and the same group continued to breastfeed more compared with the control group (χ2=4.50, p=.049). Conclusion: This study suggests that the preterm breastfeeding program had a positive effect on breastfeeding self-efficacy, breastfeeding attitude, and extending the breastfeeding period among preterm mothers.
Since the mean age of breast cancer in women living in developing countries, compared with those in developed countries, is lower by about 10 years, repetition of mammography can play an important role in reducing morbidity and mortality. Hence, this study aimed to investigate the relationship between family history of breast cancer and risk perception and its impact on repetition of mammography. In this cross-sectional study, 1,507 women aged 50 years and older, referred to the mammography center of Regions 1 and 6 in Tehran, Iran, were enrolled. Data were collected using a self-report questionnaire and analyzed using SPSS and LISREL. According to our findings, knowledge about the time interval of mammography was found to have the highest correlation with repetition of mammography (r=0.4). Among the demographic variables, marital status (${\beta}$= -0.1) and family history of breast cancer (${\beta}$=0.1) had the most direct and significant impact on repetition of mammography (P <0.05). Among the other variables studied, knowledge (${\beta}$=-0.5) had the highest direct and significant impact on repetition of mammography (P <0.05). Family history of breast cancer was one of the predictors of repetition of mammography, but the results did not prove any relationship with risk perception. Further studies are needed to assess the effect of risk perception and knowledge about time interval on the initiation and continuation of mammography.
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