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Effect of diabetes-specific oral nutritional supplements with allulose on weight and glycemic profiles in overweight or obese type 2 diabetic patients

  • Jihye Tak;Minkyung Bok;Hyunkyung Rho;Ju Hyun Park;Yunsook Lim;Suk Chon;Hyunjung Lim
    • Nutrition Research and Practice
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    • v.17 no.2
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    • pp.241-256
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    • 2023
  • BACKGROUND/OBJECTIVES: Diabetes-specific oral nutritional supplements (ONS) have anti-hyperglycemic effects, while D-allulose exerts anti-diabetic and anti-obesity effects. In this study, we investigated the efficacy and safety of diabetes-specific ONS, including allulose, on glycemic and weight changes in overweight or obese patients with type 2 diabetes mellitus (T2DM). SUBJECTS/METHODS: A single-arm, historical-control pilot clinical trial was conducted on 26 overweight or obese patients with T2DM (age range: 30-70 yrs). The participants were administered 2 packs of diabetes-specific ONS, including allulose (200 kcal/200 mL), every morning for 8 weeks. The glycemic profiles, obesity-related parameters, and lipid profiles were assessed to evaluate the efficacy of ONS. RESULTS: After 8 weeks, fasting blood glucose (FBG) level significantly decreased from 139.00 ± 29.66 mg/dL to 126.08 ± 32.00 mg/dL (P = 0.007) and glycosylated hemoglobin (HbA1c) improved (7.23 ± 0.82% vs. 7.03 ± 0.69%, P = 0.041). Moreover, the fasting insulin (δ: -1.81 ± 3.61 μU/mL, P = 0.017) and homeostasis model assessment for insulin resistance (HOMA-IR) (δ: -0.87 ± 1.57, P = 0.009) levels decreased at 8 weeks, and body weight significantly decreased from 67.20 ± 8.29 kg to 66.43 ± 8.12 kg (P = 0.008). Body mass index (BMI) also decreased in accordance with this (from 25.59 ± 1.82 kg/m2 to 25.30 ± 1.86 kg/m2, P = 0.009), as did waist circumference (δ: -1.31 ± 2.04 cm, P = 0.003). CONCLUSIONS: The consumption of diabetes-specific ONS with allulose in overweight or obese patients with T2DM improved glycemic profiles, such as FBG, HbA1c, and HOMA-IR, and reduced body weight and BMI.

Concentration of heavy metals in shellfishes and health risk assessment from Korean coastal areas

  • Ka Jeong Lee;Eun Hye Kang;Minchul Yoon;Mi Ra Jo;Hong Sik Yu;Kwang Tae Son
    • Fisheries and Aquatic Sciences
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    • v.25 no.12
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    • pp.626-636
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    • 2022
  • Shellfish are exoskeleton-bearing aquatic invertebrates that consume various organic and inorganic substances floating in seawater through filter feeding. Heavy metals are known as absorbed and accumulated in seawater. Some of the toxic heavy metals are highly accumulated in seawater, and exposure to them can cause a variety of risks to the human body. Since Koreans like to eat seafood, they are more likely to be exposed to contaminated seafood with heavy metals. In this study, nine types of heavy metals were analyzed on ten different shellfish species in the coastal area of South Korea. The risk assessment was also done on shellfish in which heavy metals were detected. Zinc (Zn) and copper (Cu) were identified at an average of 56.7 mg/kg (6.70 to 466 mg/kg) and 13.2 mg/kg (0.064 to 143 mg/kg), respectively. Lead (Pb) average of 0.208 mg/kg (0.000750 to 1.02 mg/kg), cadmium (Cd) average of 0.454 mg/kg (0.0388 to 1.56 mg/kg) and mercury (Hg) average of 0.0266 mg/kg (0.00548 to 0.174 mg/kg) were identified. Additionally, arsenic (As), chromium (Cr), nickel (Ni), and silver (Ag) were also identified as average concentrations of 4.02 (0.460 to 15.0 mg/kg), 0.167 (< limit of quantification [LOQ] to 0.820 mg/kg), 0.281 (< LOQ to 1.46 mg/kg), and 0.158 mg/kg (< LOQ to 1.15 mg/kg). The result indicates that the monitoring results of heavy metals in most shellfish satisfied the Korean standard. However, Pb and Cd have exceeded some foreign standards, such as the United States and the EU. The permissible human exposure calculated using the heavy metal intake and detection amount was lower than the Joint FAO/WHO Expert Committee on Food Additives human safety standard, and the risk of heavy metals from shellfish consumption was at an acceptable level.

A Cluster Based Energy Efficient Tree Routing Protocol in Wireless Sensor Networks (광역 WSN 을 위한 클러스팅 트리 라우팅 프로토콜)

  • Nurhayati, Nurhayati;Choi, Sung-Hee;Lee, Kyung-Oh
    • Proceedings of the Korea Information Processing Society Conference
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    • 2011.04a
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    • pp.576-579
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    • 2011
  • Wireless sensor network are widely all over different fields. Because of its distinguished characteristics, we must take account of the factor of energy consumed when designing routing protocol. Wireless sensor networks consist of small battery powered devices with limited energy resources. Once deployed, the small sensor nodes are usually inaccessible to the user, and thus replacement of the energy source is not feasible. Hence, energy efficiency is a key design issue that needs to be enhanced in order to improve the life span of the network. In BCDCP, all sensors sends data from the CH (Cluster Head) and then to the BS (Base Station). BCDCP works well in a smallscale network however is not preferred in a large scale network since it uses much energy for long distance wireless communication. TBRP can be used for large scale network, but it weakness lies on the fact that the nodedry out of energy easily since it uses multi-hops transmission data to the Base Station. Here, we proposed a routing protocol. A Cluster Based Energy Efficient Tree Routing Protocol (CETRP) in Wireless Sensor Networks (WSNs) to prolong network life time through the balanced energy consumption. CETRP selects Cluster Head of cluster tree shape and uses maximum two hops data transmission to the Cluster Head in every level. We show CETRP outperforms BCDCP and TBRP with several experiments.

Firms' Switching Intention to Cloud Based Digital Trade: Perspective of the Push-Pull-Mooring Model

  • In-Seong Lee;Sok-Tae Kim
    • Journal of Korea Trade
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    • v.26 no.6
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    • pp.20-40
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    • 2022
  • Purpose - In recent times, the international trade environment has been changing rapidly, centering on the online market. In the post-COVID-19 era, small and medium-sized trading companies are facing the problem of not being properly provided with overseas market research, market trend analysis, and trade-related information. Cloud-based digital trade is being sought as an alternative to solve these problems; however, there is a lack of research on the intention to switch to digital trade among small and medium-sized trading companies. Therefore, this study empirically analyzes the intention to switch to digital trade based on the migration theory, and through this, attempts to identify each factor that affects the intention to switch to digital trade. Design/methodology - In this study, in order to identify factors influencing intention to switch to digital trade and innovation resistance of small and medium-sized trading companies, through previous research on migration theory and the PPM (Push, Pull, Mooring) model, each variable was selected for the purpose of the study. Based on this, a research model was established for the factors affecting switching to digital trade of small and medium-sized trading companies and empirically analyzed. In addition, considering the differences in the innovation propensity and maturity of information infrastructure of trading companies as the recipients of innovation, this study analyzes the moderating effect of the mooring effect and seeks ways to establish specific strategies according to the degree. Findings - As a result of empirical analysis, the pull effect was found to have the greatest influence on intention to switch to digital trade. However, the pull factor was found to have an effect on user resistance, and it was confirmed that it was a factor simultaneously inducing positive and negative consumption behaviors among users. In addition, it was found that the higher the company's innovation propensity, the higher the pull effect's influence on the intention to switch, and analysis showed that the push effect had no influence. In addition, companies with high information infrastructure maturity were expected to have a relatively high level of intention to switch compared to companies with low information infrastructure maturity, and the difference between the two groups was found not to be statistically significant. Originality/value - This study is a timely study in that it demonstrated the effect on the switching to cloud-based digital trade for small and medium-sized trading companies and that the cloud system related to digital trade is in full swing. There are academic implications in that it revealed that the pull effect is an important factor in the intention to switch to cloud service. Practical implications were presented in that small and medium-sized trading companies suggested ways to increase the value of the cloud system for switching to digital trade and a way to increase the switching ratio by minimizing the mooring effect. In addition, the study argues that active institutional support from the government is needed to activate cloud service.

Behavioral responses and tolerance limits of wild goldeye rockfish Sebastes thompsoni to high temperature exposure (고 수온 노출에 따른 자연산 불볼락 Sebastes thompsoni의 행동반응 및 내성 한계)

  • Sung-Jin Yoon;Jin-Hyeok Park
    • Korean Journal of Environmental Biology
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    • v.40 no.3
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    • pp.247-254
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    • 2022
  • To investigate the tolerance limit and critical thermal maximum (CTM), behavioral responses of wild goldeye rockfish Sebastes thompsoni according to exposure to high water temperature were observed using a continuous behavior tracking system. As a result, behavioral index (BI) of S. thompsoni in each temperature (20.0, 25.0, and 30.0℃) showed a significant difference (p<0.05) when compared with the value measured in a stable condition of 15.0℃. The activity level of S. thompsoni exposed to 25.0℃ decreased sharply after 20 hours. Their rest time at the bottom of experiment chamber increased, and their normal swimming and metabolic activities were disturbed. In addition, at a high water temperature of 30.0℃, S. thompsoni reached the limit of resistance and showed a sub-lethal reaction of swimming behavior, with energy consumption in the body increased and all test organisms died. In conclusion, the eco-physiological response of S. thompsoni to water temperature varied greatly depending on the fluctuation range of the exposed temperature and the exposure time. In addition, the tolerance limit of S. thompsoni to high water temperature was predicted to be 25.0-30.0℃. The maximum critical thermal that had a great influence on the survival of this species was found to be around 30.0℃.

An Interactive Method between HSE System and Wearable Components through Analysis on Risk Scenarios (위험 시나리오 분석을 통한 스마트 HSE 시스템 및 웨어러블 컴포넌트 연동방안)

  • Shon, DongKoo;Lim, Dong-Sun;Im, Kichang;Park, Jeong-Ho;Kim, Jong-Myon
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.5
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    • pp.407-416
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    • 2018
  • The development of modern technology has rapidly grown the field of wearable devices. Wearable equipments should satisfy low power consumption and small/lightweight because of characteristics of body wearing. In this paper, an overview of wearable equipments is explained, and wearable device market is investigated. In addition, we investigate developed technology of wearable components, which is divided into component and communication technology. Meanwhile, a smart HSE system is required to meet the demand of the society for the serious industrial accident. To address this issue, we propose an interactive method between the wearable component and the HSE system, which are expected to be effective in safety management. As a detailed case study, a risk scenario is made with risk factors in welding workshop, and then we propose an interactive method between a wearable component and an HSE system that can reduce the risk. This proposed method is useful to achieve high level of worker's safety.

A Study of Activation Approaches by the on the Analysis Problems and Success Cases of Traditional Markets (재래시장의 문제점과 사례 분석을 통한 활성화 방안)

  • Lee, Jae-Han;Kim, Kyu-Won;Yu, Jong-Pil
    • The Korean Journal of Franchise Management
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    • v.1 no.1
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    • pp.19-42
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    • 2010
  • Since circulation market whole surface opening, traditional market is real condition that is looked away more gradually to consumer as reasons of international retail firms and domestic enterprise firms to enter distribution industry, internet mail order rapid increase by information-oriented society, the pursuit of upgradation and normalization by elevation of income level and consumption pattern change that consideration convenience with young consumers as the central figure. Therefore, the purpose of this study is to analyze stagnation cause of traditional market and problem within a change of new distribution environment, and to develop new approaches for dealing with domestic traditional market relationship prompting competition through activation example analysis of foreign traditional market and domestic traditional market. The result of the study indicated that there are a lot of cases that are begun by a few's merchant with leadership that has been will which is strong in activation in beginning in market's occasion that succeed in activation. In particular, software side such as operational efficiency or marketing expertise strengthening of management is that effect is high relatively than hardware side market activation. Also essential to the settlement of credit transactions using credit cards is important for expanding the effort, for the expansion of credit card merchant credit card advantage and raise awareness among traders about the expected effects is needed. Though these study finding submits plan that create market ecosystem so that many consumers may become place that could visit naturally and create pleasure and convenience, and time, monetary, psychological value of shopping to traditional market, there is sense.

Recent Research Status of Postharvest Management of Broccoli (브로콜리 수확후 관리의 최근 연구 동향)

  • Choi, Ji-Weon;Lee, Woo-Moon;Kwak, Jung-Ho;Kim, Won-Bae;Kim, Ji-Gang;Lee, Seung-Ku;Cho, Mi-Ae
    • Journal of the Korean Society of International Agriculture
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    • v.23 no.5
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    • pp.497-502
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    • 2011
  • Broccoli is considered as one of the functional foods to offer a hearty supply of the nutrient-rich vegetable in the world. Broccoli contains high level of phytochemicals, and that is selected as one of the top 10 vegetables for human health promotion. Especially, glucosinolates and flavonoids are well known as anti free oxygen radicals in vegetables and fruits. In Korea, broccoli consumption has increased to well known on the health-beneficial vegetables since 2000. However, broccoli has many problems of postharvest management since the quality of harvested heads quickly declines. Major problems are the floret yellowing, wilting, off-odor, and decay. The multiple postharvest applications improve broccoli quality and cold treatment including pre-cooling extends on the shelf-life with circumstance of optimum storage which is 0℃ temperature and a range of 95-100% relative humidity. Controlled atmosphere or modified atmosphere packaging can be used as supplemental treatments to extend postharvest life. 1-2% O2 + 5-10% CO2 is currently recommended for broccoli. Postharvest management is important for broccoli because price fluctuations depend on harvest time and quality. In this study, we tried to review physiological change of broccoli after the harvest, storage method, and various techniques to optimize quality during distribution.

Construction and Operation of Small Solar Plant Using Smart-Off-Grid: Case of Tanzania-Korea Innovative Technology and Energy Center (스마트-독립전력망을 사용한 소규모 태양광 발전소의 건설과 운영: 한국-탄자니아 적정기술 거점센터의 사례)

  • Kim, Jisoo;Jung, Woo-Kyun;Ha, Bo-Ra;Moon, Ji-Hyun;Rhee, Herb;Ahn, Sung-Hoon
    • Journal of Appropriate Technology
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    • v.5 no.2
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    • pp.62-69
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    • 2019
  • Supplying stable electric power is one of the important objectives of the Official Development Assistance (ODA) because it is strongly related with improving living standards and income levels in the region. However, rural areas in many developing countries are not properly connected to national power grids, and even areas connected to national power grids are frequently blacked out due to limitations in power capacity. These lack of electric power is a major obstacle to improving income levels and improving living standards in those areas. The Korea-Tanzania Innovative and Energy Center (iTEC), which was established by Seoul National University in cooperation with the Nelson-Mandela Africa Institute of Science and Technology and Technology (NM-AIST) try to build a small solar power plant using a smart-off grid in rural area of Tanzania, where there is no electricity. 10 kW and 7 kW solar power plants are built in Mkalama Village in Kilimanajaro Region and Ngurdoto Village in Arusha Region to provide power to about 50 households each. In addition, smart monitoring systems were installed to collect data about status of power system and power consumption of each house. iTEC seeks for sustainable improvement the income level and quality of life of rural residents in developing countries through the construction of small solar power plants using smart-off grid, and the implementation of various connected projects.

A Cross-Cultural Study of Value Structure and Environmental Consumerism: The Case of Korean and United States Consumers (가치구조와 환경소비주의에 관한 타 문화간 비교연구: 한국과 미국 소비자사례)

  • Kim, Yeonshin;Choi, Sejung Marina;Nora Rifon
    • Asia Marketing Journal
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    • v.10 no.4
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    • pp.35-64
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    • 2009
  • In an effort to increase our understanding of green buying behavior, the present study proposes and tests a comprehensive model of how values influence attitudes toward the environment and preferences for green products in a cross-cultural setting. Data were collected from a survey with consumers in two cultures, diametrically different on values salient to environmental consumerism, the U.S. and Korea. As a result of model testing both at the national and multi-group levels, a refined, final model is presented. While the core human values were found to relate to environmental attitudes and green buying behavior, the patterns of the relationships among the variables emerged to differ between the two cultures, highlighting the importance of cross-cultural investigations in this area. Results suggest that biospheric values significantly influence environmental attitudes and green consumption in both countries. However, the effects of egoism were significant among American respondents whereas altruism appeared to have a significant influence on attitude and behavior in the Korean sample. Findings of this study should aid international marketers in their understanding of what drives consumers' green buying behavior in different cultural settings.

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