• 사상체질의학회지
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• 제21권1호
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• pp.227-236
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• 2009

1. Objectives As a basic trial for identification of Sasang constitutional gene marker, we genotyped and analysed statistical relationships of STR(short tandem repeat) alleles and its distribution in each constitution. 2. Methods After obtaining basic constitutional data with questionnaire (QSCC II), decision of constitution was made by 3 different constitution specialists' diagnosis, and only the samples of specialists' agreement of each constitution by discussion were taken into this research. Using multiplex PCR kit, total 146 constitutional samples were amplified in 16 autosomal STR marker, genotyped, and analysed statistically. Among 16 markers, 15 were analysed in this study excluding the amelogenin marker is used for in gender identification. 3. Results and Conclusions It is difficult to determine the relationship between constitution and STR marker as the sample size is small, however, Penta D and vWA were shown to be related statistically with constitution. It has been know that STRs has no genetic informations, however there are some recent research results showing STRs as a regulatory element, relationship between microsatellite instability and repeat number and size, and post-transcriptional sigualing. STRs which is not known about its function currently, are proposed to have function and/or regulatory activities anyhow with Sasang constitution. It is believed that the results of this study can halp determine and deatify the markers related to Sasang Constitutional Medicien.

• 사상체질의학회지
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• 제20권3호
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• pp.133-141
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• 2008

l. Objectives This study aims to know the coefficient of five Sasang constitution diagnosis factors' concordance in and among Oriental Medical Clinics, which are important to diagnose Sasang constitution, 2. Methods We collected 701 subjects in Oriental Medical Clinics, who were diagnosed by experts, and they marked the priority order of Sasang constitutional factors in paper. 3. Results 1) The concordance of priority order about Sasang constitutional factors was significantly associated within Oriental Medical Clinics. 2) The concordance of priority order of Sasang constitutional factors was not significantly associated among 12 Oriental Medical Clinics, so we find out that each medical clinics has a different point of view of deciding the rank of diagnosis factors. 3) We show that the factor of Sasang constitutional drug response was the most important one to confirm Sasang constitution and factors have a different order according to clinic type and qualification of experts 4. Conclusions Sasang constitution expect has their own view in diagnosis priority order and that was different among them.

• 사상체질의학회지
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• 제21권3호
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• pp.76-88
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• 2009

1. Objectives: We would know what kind of symptom are different according to Cold and Heat characteristics and health state. We also tried to suggest the development of Sasang Constitution diagnosis model considering of them. 2. Methods: We recruited 1,523 subjects between 10 and 80, excluding individuals who have physically or psychologically serious disease or women in pregnancy in the 21 Oriental Medical Clinics. We seperated group according to Cold and Heat characteristics and health state in CRF(Case Report Form, C-2009-002439) questionnaire and we also developed Sasang constitution diagnosis program to compare agreement according to sex and age group with Cold/Heat and health state one. 3. Results: The number of discordance items are much more than that of accordance items in group seperated according to Cold and Heat, and Health state Sasang constitution agreement rate of Cold/Heat and health state group is higher than that of total group through program. When we diagnosed Sasang constitution with different group characteristics to know the group differences, the disparity rate of the group according to Heat/Cold and Health state is lower than that of the group according to sex and age. 4. Conclusions: As Sasang constitution characteristics are different according to Cold/Heat group and Health state classification, we can upgrade Sasang constitution agreement rate with questionnaire considered of Heat/Cold and health state.

• 사상체질의학회지
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• 제22권2호
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• pp.48-59
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• 2010

1. Objectives: Sasang Medicine has been based on different medicine approach because people were different, so, this was a little different concept about health compared to other oriental and western medicine focused on existing Yangsaeng theory. We were announced Constitution health indicators for women, and this was follow-up study designed to identify Constitutional health indicators in men. 2. Methods: We recruited 171 men between 10 and 80, excluding individuals who have physically or psychologically serious disease among Korean population in Traditional Korea Clinics. They were diagnosed by Sasang Constitution specialists and confirmed clinically with Sasang constitution drug response with past medical records. We used CRF(Case Report Form, C-2009-002439) as measurement of physiological and pathological symptoms and SF-36 (Short Form-36) as measurement of health state. We analyzed association between physiological and pathological symptoms and health state with Two-way ANOVA. 3. Results: 23 items of 82 indicators in physiological and pathological symptoms were related to the quality of life, regardless of the constitution. There are 4 different symptoms associated with health state in men, such as regular of feces, hard to fall asleep, no problem in chest, feel heavy in chest according to Sasang Constitution. 4. Conclusions: From these Results, there are different items of physiological and pathological affected the Quality of life according to Sasang Constitution.

• 한국한의학연구원논문집
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• 제15권2호
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• pp.111-117
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• 2009

We intended to identify the health state of Oriental medical students and also to know how many things of health practice are in healthy group and non-healthy group classified by the THI average score, according to sasang constitution. We collected data with self-administered health questionnaires from 297 men and women, in 9 Korea oriental medical colleges. We diagnosed Sasang constitution using QSCC II and also estimated health degree using THI. Non-healthy group practiced much more health behaviors than healthy one, and there were significant difference in Taeeumin and Soeumin. Non-healthy group of Taeeumin, Soeumin and Soyangin all practiced much more constitutional health behaviors than healthy one, and Soeumin non-healthy and healthy one all practiced much less health behaviors than Taeeumin and Soyangin group. Non-healthy group practiced health behavior for health care and maintenance more than healthy-one, and health state was related with sasang constitution health care. Therefore, institutional and systematic environmental condition would be needed in practicing healthy behaviors for improving the quality of health, and especially developed health promotion programs according to Sasang constitution too.

• 사상체질의학회지
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• 제21권3호
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• pp.39-47
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• 2009

1. Objectives: In order to classify an individual into four constitution type, an oriental medical doctor utilizes various information such as face, pulse, voice, and questionnaire. When only one type of information is used, one's constitution may not be decided correctly. 2. Methods: In this paper, we propose a novel four constitution types classifier using facial images which classifies subjects into indecision group as well as Taeumin, Soeumin, and Soyangin. 3. Results: Experimental results show that it increases the classification rate though the decision rate is rather decreased, which is more effective and reliable than conventional classifiers without indecision. 4. Conclusion: For the effective classification, we have found that it is more useful to add an indecision group which requires more information to be properly classified into one constitution type.

• 사상체질의학회지
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• 제30권1호
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• pp.32-42
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• 2018

The purpose of this study aimed to know the association between seven health practices and self rated health by Sasang constitution. We recruited 367 subjects aged from 30 to 59. KS 15 questionnaire was used to classify Sasang constitution and visual analogue scale was used to estimate self rated health. Chi-square test was used to know the difference of occupation distribution by Sasang constitution. Anova test, T-test and Chi-square test also used to analyze the difference of self rated health between the health practice group and non-health group in individual Sasang constitution. SPSS 21.0K was used and significant p was <.05. Regular morning meal, non-snaking, good sleeping and sufficient exercise had higher self rated health score (p<.05). Regular morning meal, good sleeping and sufficient exercise had higher score in Tae-eumin (p<.05). Good sleeping had higher self rated health score in Soeumin and Soyangin (p<.05). These results suggest there is possibility that health practices for health promotion could be different according to Sasang constitution.

• 사상체질의학회지
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• 제30권1호
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• pp.50-57
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• 2018

Objectives This study was aimed to examine cold hypersensitivity tendency in the hands, feet and abdomen according to Sasang constitution among Koreans. Methods Multi stage stratified sampling was conducted for random selection of 1,100 participants aged ${\geq}19years$, based on sex, age, region in Oct.2010. Cold hypersensitivity was measured using a questionnaire to score the extent of cold hypersensitivity in the hands, feet, abdomen. Subjects' constitution was diagnosed by Korea Sasang Constitutional Diagnostic Questionnaire (KS-15). The cold hypersensitivity scores according to Sasang constitution were analyzed using logistic regression and one way ANOVA. Results On the one way ANOVA, Soeumin group's cold hypersensitivity in the hands and feet scores were significantly higher than those of Taeeumin and Soyangin groups. However, there was no significant difference in the abdominal cold hypersensitivity scores by constitution. The regression analysis, adjusted for age, sex, and sociodemographic variables, showed that Soeumin group had significantly higher cold hypersensitivity effects of the hands (${\beta}=0.105$, p = 0.002) and feet (${\beta}=0.099$, p = 0.003) than Taeeumin group. Conclusions Soeumin group significantly had higher cold hypersensitivity scores in the hands and feet than Taeumin and Soyangin group.

• 사상체질의학회지
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• 제24권1호
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• pp.21-31
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• 2012

1. Objectives : In this study we derived constitutional characteristics both by using questionnaire on character and symptom and by collecting objective measurement data through face, body shape. Furthermore, by developing a program, we intend to help one's diagnosis of Sasang constitution. 2. Methods : Through November 2007 to July 2009, we obtained questionnaire, face, and body shape data of 958 constitution confirmed subjects within the age range of 10-80 from 19 oriental medical facilities in the country. According to sex, we divided the subjects into two groups as real constitution and non-constitution group respectively. We analyzed the questionnaire through chi-square test (p<.01) and facial and body shape data through unpaired T-test (p<.01). By using weight law for questionnaire and euclidean distance for body shape and face data, we expressed constitution possibility to develop a supplementary program. 3. Results : The concordance rates of constitutional diagnosis by using the program for Taeeumin, Soeumin, Soyangin are, 76.7%, 61.5%, 67.4% resulting in 69.6% in male and 64.1%, 64.7%, 65.1%, resulting in 64.7% In female respectively. New cases tested on the program showed concordance rate of 65% in male and 62% in female with real constitution. 4. Conclusion : The constitutional diagnostic program based on the face, body shape and questionnaire, may have significant meaning as a supplementary tool in the constitutional diagnosis for clinical expert.

• 사상체질의학회지
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• 제23권2호
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• pp.218-229
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• 2011

1. Objectives: This study is to investigate the relationship between Intima Media Thickness(IMT) of common carotid artery and Sasang Constitution. 2. Methods: 839 persons, over 40 years old, participated in community-based cohort of Korea Genome and Epiedemiology Study (KOGES) in Wonju City and Pyeongchang City of South Korea from June 2006 to February 2008. The diagnosis of Common carotid Intima Media Thickness was evaluated by B Mode ultrasonography, cardiovascular risk factors were checked using questionnaire and blood samples. Constitution was verified by a Sasang constitution specialist according to the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Multiple regression analysis and logistic regression analysis were performed with SPSS. 3. Results: There were significantly high values in waist circumference, fasting blood sugar, systolic blood pressure, diastolic blood pressure, triglyceride, HOMA-IR and hsCRP in Taeeumin and low in HDL-cholesterol and adiponectin in Taeeumin. There were significantly high value in Common Carotid Intima Media Thickness in Taeeumin. Age was the significant cardiovascular risk factor irrespective of Sasang constitution in all participants. There was a positive correlation between smoking and Soyangin in all participants and men. There were positive correlations between LDL-cholesterol, BMI and Taeeumin in all participants and men. There were positive correlations between hsCRP and Soeumin in all participants and men. There was significantly high odds ratio of Taeeumin over Soeumin in common carotid Intima Media Thickness. 4. Conclusions: Regimens on cardiovascular diseases should be considered according to Sasang constitution. There are more sensitive risk factor in each constitution; smoking in Soyangin, LDL-cholesterol and BMI in Taeeumin, hsCRP in Soeumin.