• Title/Summary/Keyword: Constituent

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Hopatoprotective Effects of Extracts form Artemisia iwayomogi (한인진 추출물의 간질환모델에 대한 활성)

  • Lee, Soon-Bok;Jeong, Cheol;Jeong, Seong-Hak;Lee, Sun-Mee;Shim, Sung-Bo;Cho, Tai-Soon
    • Biomolecules & Therapeutics
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    • v.5 no.2
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    • pp.194-201
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    • 1997
  • The hepatoprotective activity of six extracts (BE, EE, HH, PS-1, PS-2, KP) from Artimisia iwayomogi was investigated against experimentally produced hepatic damages. Silymarin, DDB and UDCA were used as reference compounds. Treatment with PS-1 extract reduced hepatic demages induced by $CCl_4$, acetaminophen and ANIT but it did not alter ethionine-induced hepatotoxicity In addition, PS-1 extract showed a protective effect against chronic $CCl_4$-induced hepatotoxicity as well as liver regeneration. PS-2 and KP extracts exhibited significant antihepatotoxic effects on D-galactosamine-induced hepatitis. Treatment with EE extract inhibited ethionine-induced fatty liver. These data indicate that the PS-1 extract is the roost hepato-protective constituent and rationalize the traditional use of this plant in hepatobiliary disorders.

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Development of a Continuous High-Speed Single-Kernel Brown Rice Sorting Machine Based on Rice Protein Content

  • Natsuga, Motoyasu;Nakamura, Akitoshi;Kawano, Sumio
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1616-1616
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    • 2001
  • To select kernels for breeding that have required constituent content from either naturally distributed samples or artificially mutated ones, it is necessary to process batch samples in a short time. The constituent content of single-kernel grains such as wheat and rice has been determined using conventional bench type NIR instruments; however, it takes a lot of time and effort. Shizuoka Seiki (Fukuroi-city, Japan) and NFRI (National Food Research Institute) of MAFF (Ministry of Agriculture, forestry and Fisheries of Japan) have jointly developed a continuous high-speed single-kernel brown rice sorting machine based on rice protein content. It consists of several sections such as a feeding mechanism, measuring unit, sorting mechanism and controlling PC. The feeding mechanism picks up single-kernel brown rice from the hopper (maximum of 5kg storage capacity) and sends it to the measuring unit. A spectrum of the brown rice is obtained in the measuring unit, which consists of a near-infrared array sensor. The brown rice is then sorted in the sorting mechanism based on its protein content estimated by the controlling PC. In the present study, measuring speed was approximately 500ms for the full spectrum range and overall sorting speed was approximately 2.8s for one kernel. Accuracy of estimation was approximately SEP=0.5% of dry matter protein content for nonglutinous rice.

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Subjective Hand and Sensibility of Knit Fabrics According to Preference Segmentation (니트 소재의 선호도 세분화에 따른 주관적 태와 감성 비교)

  • Ro, Eui-Kyung;Kim, Seong-Hung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.34 no.10
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    • pp.1611-1620
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    • 2010
  • This research compares the difference of each preference segments' subjective hands and sensibilities in order to analyze the correlations among preference, subjective hands, and sensibilities. Preference segments were classified into wool, acrylic, and long stitch length-preferred clusters in previous research. To evaluate the subjective hands and sensibilities of knit fabrics, the 20's and 30's women rated twelve knit fabrics by touching, using a questionnaire with a seven-point semantic differential scale. These twelve knit fabrics were differentiated by controlling the mixture ratio and stitch length using a computer-controlled automatic flat knit machine. The difference of each preference segments' subjective hands and sensibilities was determined using the conjoint analysis. The clusters perceived the subjective hands and sensibilities differently according to preferred constituent characteristics. There was no correlation between surface unevenness and preference in wool-preferred cluster, while there were negative correlations in other clusters. The acrylic-preferred cluster had a preference in coolness compared to other clusters; in addition, the long stitch-preferred cluster preferred flexibility/bulkiness and extensibility than the others. All clusters preferred modem and natural sensibilities that were caused by different constituent characteristics of knit fabrics.

Effect of Each Constituent-Herb of Sagoonja-Tang on the Change of Corticosterone Level induced by Heat Stress in Mice (Heat Stress로 유발된 생쥐의 혈중 corticosterone 농도변화에 대한 사군자탕(四君子湯) 구성약물의 효능)

  • Jo Yong-Kook;Lee Tae-Hee
    • Herbal Formula Science
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    • v.11 no.2
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    • pp.147-158
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    • 2003
  • This study aimed to investigate the effect of each constituent-herb of Sagoonja-Tang on the plasma corticosterone level in mice exposed to heat stress. Each formula(0.5g/kg, 1.0g/kg) was injected intragastrically to mice exposed to forced hot water swimming(42$^{\circ}C$, 3min) before measuring the change of plasma corticosterone level of mice. The results were as follows: 1. At 15 minutes after the heat stress for 3 minutes the most significant increase of corticosterone level was shown. 2. Ginseng group didn't show significant changes. 3. Atractylodis group showed significant decrease at 0.5g/kg dose(P<0.05). But it showed slightly increase at 1.0g/kg dose. 4. Poria group didn't show significant changes. 5. Glycyrrhizae group showed slightly increase, but insignificant. These data revealed that Atractylodis macrocephalae Rhizoma might have the anti-stress effect through the control of plasma corticosterone level in mice exposed to heat stress.

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Effect of Each Constituent-Herb of Sagoonja-Tang on the Change of Corticosterone Level induced by Cold Stress in Mice (Cold Stress로 유발된 생쥐의 혈중 corticosterone 농도변화에 대한 사군자탕(四君子湯) 구성약물의 효능)

  • Kwon Yong-Uk;Lee Tae-Hee
    • Herbal Formula Science
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    • v.11 no.2
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    • pp.83-94
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    • 2003
  • This study aimed to investigate the effects of each constituent-herb of Sagoonja- Tang on the plasma corticosterone level in mice exposed to cold stress. Sagoonja-Tang is composed of Ginseng Radix, Atractylodis Radix, Poria, and Glycyrrhizae Radix. Each constisuent-herb(0.5g/kg, 1.0g/kg) was administered intragastrically to mice 1hr prior to expose to forced cold water swimming($4{\circ}C$, 3min) before measuring the change of plasma corticosterone level of mice. The results were as follows: 1. At 30 minutes after the cold stress for 3 minutes the most significant increase of corticosterone level was shown. 2. Ginseng group(PGR group) didn't show any significant changes. 3. Atractylodis group(AR group) showed significant decrease at 0.5g/kg dose (P<0.01). But it didn't show significant changes at 1.0g/kg dose. 4. Poria group(P group) didn't show significant changes. But it showed slightly increase at 1.0g/kg dose. 5. Glycyrrhizae group(GR group) didn't show significant changes. These data revealed that Atractylodis macrocephalae Rhizoma might have the anti-stress effect through the control of plasma corticosterone level and the dose of herbs had a different effect on the plasma corticosterone level in mice exposed to cold stress.

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Effects of Banhaonpaetang(半夏溫肺湯) extract and its Constituent herbs on the Contraction of Isolated Guinea Pig Trachea Smooth Muscle (반하온폐탕(半夏溫肺湯) 및 그 구성약물(構成藥物)이 실험(實驗) 동물(動物)에 미치는 영향(影響))

  • Song, Jin-Oh;Han, Sang-Hwan
    • The Journal of Internal Korean Medicine
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    • v.13 no.2
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    • pp.1-15
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    • 1992
  • This study has been carried out to investigate the effects of Banhaonpaetang extract and its constituent herbs on the contractile force of Isolated Guinea pig trachea smooth muscle and to elucidate its mechanism. The results were as follows; 1. Banhaonpaetang significanly inhibitd the contractile force of isolated guinea pig trachea smooth muscle pretreated by histamine. 2. Banhaonpaetang significantly inhibited the contractile force of isolated guinea pig trachea smooth muscle pretreated by acetylcholine. 3. Radix Asari(細辛), Flos Inulae(旋覆花), Pericarpium Citri Nobilis(陳皮) and Radix Ginseng(人蔘) extract significantly inhibited the contractile force of isolated guinea pig trachea smooth muscle pretreated by histamine. 4. Radix Asari(細辛), Cortex Cinnamomi(桂心), Flos Inulae(旋覆花), Pericarpium Citri Nobilis(陳皮) and Radix Ginseng(人蔘) extract significantly inhibited the contractile force of isolated guinea pig trachea smooth muscle pretreated by acetylcholine. 5. The effects of Banhaonpaetang extract on the changes of plasma ACTH in rats were shown to be insignificant. 6. The effects of Banhaonpaetang extract on the changes of serum electrolytes were shown to be significant in $K^+$ and $Ca^{2+}$.

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Categorization of Middle school students' Math Learning Style Preferences and Comparison of Academic Characteristics (중학생의 수학학습양식 선호유형의 범주화와 학습 특성 비교)

  • Paik, Hee Su
    • School Mathematics
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    • v.15 no.1
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    • pp.15-35
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    • 2013
  • The purpose of the research is to categorize math learners into pattern through those tools that distinguish math learning style for middle school students. On the ground of survey for 976 middle school students, the fact that there are 16 different math learning style at the result of cluster analysis is confirmed and the results are compared and analyzed previous research. Also according to the each constituent of math learning style, dissimilarity of distribution about learner of different sexes and grades are analyzed. It's helpful to understanding the whole characteristics of learners regarding math learning to figure out their cognitive and affective learning styles through the tools to distinguish their math learning styles.

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Multiscale Simulation for a Crack Behavior in Heterogeneous Materials (비균질 재료에서의 균열거동평가를 위한 멀티스케일 수치해석)

  • Fatoni, Nurul Fajriyah;Kwon, Oh Heon
    • Journal of the Korean Society of Safety
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    • v.32 no.4
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    • pp.1-6
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    • 2017
  • Functionally Graded Materials (FGM) as advanced heterogeneous composite materials have a higher performance than a conventional composite or bimaterial composite under some severe environments. As a heterogeneous material, FGM is commonly used in spacecraft, defense, nuclear and automotive industries due to its excellent properties. The purposes of this study are to evaluate the stress distribution and crack behaviors by the multiscale simulation. FGM contains two or more than two materials that the composition is structured continuously. Two types of FGM model are suggested, which are created by arbitrary prediction of the volume fraction and the exponential function. Aluminum as the metal matrix constituent and silicon carbide as the ceramic particle constituent are structured gradually by two types and the three point bending test also estimated. Moreover, two kinds of crack location were introduced in order to get the influences of material property distribution on the stress intensity factor. From the results we found that the stress intensity factors are increased in the case from softer to stiffer material, while vice versa.

Time-dependent and inelastic behaviors of fiber- and particle hybrid composites

  • Kim, Jeong-Sik;Muliana, Anastasia
    • Structural Engineering and Mechanics
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    • v.34 no.4
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    • pp.525-539
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    • 2010
  • Polymer matrix composites are widely used in many engineering applications as they can be customized to meet a desired performance while not only maintaining low cost but also reducing weight. Polymers can experience viscoelastic-viscoplastic response when subjected to external loadings. Various reinforcements and fillers are added to polymers which bring out more complexity in analyzing the timedependent response. This study formulates an integrated micromechanical model and finite element (FE) analysis for predicting effective viscoelastic-viscoplastic response of polymer based hybrid composites. The studied hybrid system consists of unidirectional short-fiber reinforcements and a matrix system which is composed of solid spherical particle fillers dispersed in a homogeneous polymer constituent. The goal is to predict effective performance of hybrid systems having different compositions and properties of the fiber, particle, and matrix constituents. A combined Schapery's viscoelastic integral model and Valanis's endochronic viscoplastic model is used for the polymer constituent. The particle and fiber constituents are assumed linear elastic. A previously developed micromechanical model of particle reinforced composite is first used to obtain effective mechanical properties of the matrix systems. The effective properties of the matrix are then integrated to a unit-cell model of short-fiber reinforced composites, which is generated using the FE. The effective properties of the matrix are implemented using a user material subroutine in the FE framework. Limited experimental data and analytical solutions available in the literatures are used for comparisons.

Quantitative Analysis of Bioconversion Constituents of Insampeadock-san Using Various Fermented Bacteria (다양한 발효균주를 이용한 인삼패독산의 생물 전환 성분의 정량 분석)

  • Lee, Kwang Jin;Gu, Min Jung;Roh, Joo Hwan;Jung, Pil Mun;Ma, Jin Yeul
    • YAKHAK HOEJI
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    • v.57 no.3
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    • pp.167-172
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    • 2013
  • Insampaedoksan (IS) is the decoction of medicinal herbs, which was commonly used for anti-inflammatory and anti-pyretic in the Korean traditional medicine (KTM). Several studies on improving efficiency or searching new efficiency by fermenting traditional herbal medicines are recently in progress. The bioconversion has been conducted on IS using various bacteria. Liquiritin, ferulic acid, hesperidin, liquiritigenin, and glycyrrhizin in IS before and after fermented IS were simultaneously analyzed. These compounds were qualitatively analyzed and quantitatively analyzed using the HPLC-DAD system. The identifications of liquiritin, ferulic acid, hesperidin, liquiritigenin and glycyrrhizin were achieved by comparing the HPLC retention time ($R_t$) and the UV absorption of five pure compounds in the IS. As a result, the increased constituents were identified to be liquiritin, liquiritigenin and glycyrrhizin, while the decreased constituent was ferulic acid and the constituent of hesperidin was similar to before and after fermentation. Insampeadock-san fermented by Lactobacillus plantarum KFRI 144 exhibited the most remarkable changes in all of fermentation.