• Clinical and Experimental Pediatrics
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• v.57 no.6
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• pp.271-277
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• 2014

Purpose: A nationwide outbreak of Mycoplasma pneumoniae pneumonia (MP) refractory to macrolide antibiotics occurred in Korea during 2011. Steroid therapy has been reported to be both efficacious and well tolerated in pediatric patients with refractory MP. We compared clinical features and laboratory characteristics between children with refractory MP requiring steroid treatment and those with macrolide-responsive MP and evaluated the risk factors associated with refractory MP. Methods: We investigated 203 children who were admitted to our institution with MP from June to November 2011. Refractory MP was defined by persistent fever over $38.3^{\circ}C$ with progressive pulmonary consolidation or pleural effusion despite administration of appropriate macrolide antibiotics for 5 days or longer after admission. Steroid therapy was initiated on the fifth day after admission for refractory cases. Results: There were 26 patients with refractory MP requiring steroid therapy. The mean duration of steroid therapy was 5.4 days and most of the patients were afebrile within 24 hours after initiation of steroid therapy. The prevalence of refractory MP was higher in patients with pleural effusion, lobar pneumonia affecting more than 2 lobes, higher levels of serum lactate dehydrogenase, increased oxygen requirements, and longer duration of hospitalization. Atopic sensitization and history of asthma were also associated with refractory MP after adjusting for age and gender. Conclusion: Children with refractory MP had more severe pneumonia. Atopic sensitization and history of asthma may be risk factors for refractory MP requiring steroid therapy in Korean children.

• Journal of Veterinary Clinics
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• v.26 no.1
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• pp.72-75
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• 2009

Pulmonary bullae are air-filled spaces within the lung parenchyma that result from the destruction, dilatation and confluence of adjacent alveoli. Pulmonary bullae are found most often in healthy, middle aged, large breed or deep-chested dogs that have no previous history of lung disease and bulla may occur as a result of emphysema, inflammation or trauma. Clinical signs include respiratory distress, anorexia, depression and tachypnea. In this study, a dog with respiratory distress by traffic accident was diagnosed as pulmonary bullae with pneumothorax using radiography at Veterinary Medical Teaching Hospital, GNU. In radiographs, various sized, smooth margin, well defined, oval shaped, gas or fluid filled multiple bullae are shown in the left cranial, left caudal and right accessory lobes. At the initial stage of observation, there were indications of four bullae, two of which were not found in the following radiograph. At the same time, there were serious indications of lung consolidation that caused respiratory distress of patient. Ultimately, the patient was expired after ten hours.

• Proceedings of the Korean Geotechical Society Conference
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• 2000.11a
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• pp.561-568
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• 2000

본 연구의 목적은 Piezocone 관입시험을 이용한 연약지반의 OCR 평가에 있어 기존의 여러 가지 해석방법들과 최근에 새롭게 제안된 방법들을 실내 모형토조에서 실측된 피에조콘 관입 실험치에 적용하여 각 해석방법들의 차이와 장단점들을 비교 분석하는데 있다. 본 연구의 연구실험방법으로는, Piezocone 관입을 위한 연약 모형지반 조성을 위하여 초대형 Slurry Consolidometer에 Free Stress 상태의 Slurry를 45일간 압밀시킨후 Automatic Computer Control Calibration Chamber (LSU/CALCHAS; Louisiana Slate University Calibration Chamber System)에 옮긴후 다시한번 압밀시키는 Two-Stage Consolidation Method를 사용하였다. 모형지반은 여러 가지 Boundary Condition들과 Stress Condition 그리고 Stress History등을 달리하여 총 5개의 지반을 조성하였다. 관입시험은 총 25개의 Piezocone 관입이 수행되어졌고, 그중 4개는 Standard 10 cm2 Piezocone이고, 나머지 21개는 Miniature Piezocone이 사용되었다. Piezocone 실험치들에 대한 여러 가지 OCR 해석방법 적용결과, Schmertmann방법은 5개 모형지반 모두에서 과다한 OCR평가를 보였으며, $B_{q}$ 방법은 일부모형지반에서 음의 OCR값으로 계산되어졌다. 그러나, Critical-Stale Soil Mechanics 와 Cavity Expansion 이론에 근거하여 Mayne(1991), Kurup(1993), Tumay et al (1995) 들이 제안한 OCR 평가방법들은 실험치와 잘맞는 경향을 보여주었다. 이와같은 이론 모델값들의 차이는 응력조건(Stress Condition)과 경계조건(Boundary Condition)들에 대한 각 해석방법들의 고려정도에 따른 결과로 판단된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.7 no.1
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• pp.102-107
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• 2004

About 20% of intestinal tuberculosis have active pulmonary tuberculosis. Intestinal tuberculosis can develop by swallowing sputum which have active pulmonary tuberculosis and by ingestion of contagious milk. We report a case of intestinal tuberculosis complicated with pulmonary tuberculosis in a 15-year old aldelescent who could not cough out sputum because of known cerebral palsy. He was admitted because of 3 day history of fever and bloody stool. Chest PA showed both upper lobe consolidation. AFB stain and AFB PCR was positive for tuberculosis. Colon study showed abscence of haustral marking and lead pipe appearance due to stenosis of ascending colon and mucosal edema. Abdominal CT scan showed mild wall thickening in ascending colon. Despite the anti-tuberculosis therapy with first line drugs, fever accompanying pleural effusion developed. Second line drug with Isoniazid and Rifampin improved clinical manifestation. After the report on sensitivity, we readjusted the regimen, and clinical manifestations improved gradually.

• Parasites, Hosts and Diseases
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• v.49 no.1
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• pp.69-72
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• 2011

Pulmonary paragonimiasis is a relatively rare cause of lung disease revealing a wide variety of radiologic findings, such as air-space consolidation, nodules, and cysts. We describe here a case of pulmonary paragonimiasis in a 27-year-old woman who presented with a 2-month history of cough and sputum. Based on chest computed tomography (CT) scans and fluorodeoxyglucose positron emission tomography (FDG-PET) findings, the patient was suspected to have a metastatic lung tumor. However, she was diagnosed as having Paragonimus westermani infection by an immunoserological examination using ELISA. Follow-up chest X-ray and CT scans after chemotherapy with praziquantel showed an obvious improvement. There have been several reported cases of pulmonary paragonimiasis mimicking lung tumors on FDG-PET. However, all of them were suspected as primary lung tumors. To our knowledge, this patient represents the first case of paragonimiasis mimicking metastatic lung disease on FDG-PET CT imaging.

• Proceedings of the KSR Conference
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• 2009.05a
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• pp.1542-1549
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• 2009

The function of subgrade in the railway is to support track load on the subgrade as well as train load. Unlike the traditional railway, the uppermost subgrade layer in the Gyeongbu high speed railway was constructed as the reinforced road bed. The reinforced road bed comprises sub-ballast in the upper part and grade ballast in the lower part. The filling material such as soil and rocks in the subgrade can be settled by consolidation of original ground, compression due to self weight, plastic displacement due to train operation, and unequal settlement due to embankment material or improper compaction, therefore many efforts have been given for sufficient compaction and use of proper filling materials in the construction stage. The purpose of this study is to investigate the deformation state of subgrade in the Gyeongbu high speed railway. The investigation on the subgrade settlement was performed by choosing representative sections suspected to be settled based on the previous GPR test results and track maintenance history, measuring the settlement for some time period after installing settlement measuring instruments on and under the reinforced road bed. and analyzing the long-term subgrade settlement data from monitoring system which was installed at the construction stage of the high speed railway.

• Tuberculosis and Respiratory Diseases
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• v.72 no.1
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• pp.55-58
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• 2012

Mycobacterium szulgai is a rare nontuberculous mycobacterium found in Korea. It is an opportunistic pathogen and is usually isolated from patients with a history of alcoholism, chronic pulmonary disease, or an immunocompromising condition. We present here a case of M. szulgai isolated from a patient with a history of pulmonary tuberculosis. A 54-year-old man was admitted with dyspnea and febrile sensation. He had a history of pulmonary tuberculosis which occurred 30 years earlier and treatment with anti-tuberculosis medication. His chest computed tomography scan showed cavitary consolidation in both upper lungs. A sputum acid-fast bacilli (AFB) smear was positive and anti-tuberculous medication was started. However, a polymerase chain reaction for mycobacterium tuberculosis was negative and anti-tuberculous medication was stopped. M. szulgai was isolated on 3 separate sputum and bronchial wash fluid AFB cultures. He was treated with clarithromycin, rifampicin, and ethambutol. After 1 month, a sputum AFB smear and culture became negative and no additional M. szulgai were isolated during a 16-month treatment.

• Cross-Cultural Studies
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• v.44
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• pp.29-58
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• 2016

'Post-memory' is the act of remembering traumatic events in history by subsequent generations who have not had direct experiences or relations with them. For this reason, the narratives of 'post-memory' are considered as re-interpretations of the past deeply influenced by current perspectives and concerns. The Chilean film NO goes back to the Referendum of 1988 in order to examine the "NO campaign" which was opposed to another eight years of continuation of the Pinochet regime. Although this campaign contributed significantly to the Chilean democratization, the filmmaker does not just celebrate it: rather he attempts to cast a critical reflection on its strategies that eventually turned democracy into a "commodity" by deploying commercial language and marketing tools for characterizing and describing it. On the other hand, the Korean movie The Attorney sheds light on the story of an attorney who, during the military regime in the 1980's, became a human rights lawyer when he tried to advocate for university students accused of violating national security law. This film reconstitutes the meaning of democracy built upon the logic of "common-sense" that privileges freedom and fundamental human rights over Statism. Despite the different historical contexts between Chile and South Korea, these two movies retell the history of a dictatorship that ended a couple of decades ago. In doing so, they raise questions about history, memory and democracy in order to deepen the understanding of current social and political circumstances while placing an emphasis on the roles and responsibilities of intellectuals during the transition to democracy and democratic consolidation.

• The Korean Journal of Cytopathology
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• v.10 no.1
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• pp.61-66
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• 1999

Angiosarcomas are rare tumors, seen most commonly in the skin and soft tissue of head and neck legion. But it has been described in numerous body sites including thyroid, breast, liver, spleen, bone, etc.. Their biological behaviors depend on the microscopic grade, site of origin, and multifocality. We report the unique cytological features of an angiosarcoma in pleural fluid. A 61-year-old woman presented with a 6 month history of dyspnea on exertion and chest pain. Chest computerized tomography(CT) revealed multiple subpleural small nodules in the right lung and widespread all space consolidation and pleural effusion in the left lung. CT of liver revealed multiple small low attenuated lesion. The smears obtained from pleural fluid showed hypocellularity with a hemorrhagic background. The tumor cells were highly pleomorphic oval or spindle in shape and presented singly, in loose groups, in knitted syncytial aggregates, and in acinar pattern. Their nuclei had vesicular chromatin with delineated, thick nuclear membranes and occasionally a large eosinophilic, prominent nucleolus. The cytoplasm was plump, thin or protected in spindly fashion. Almost ail tumor cells showed variable sized intracytoplasmic vacuoles and their nuclei were sometimes crescentic by a huge vacuole. Occasional binucleated tumor cells and mitotic figures were present. Cellular debris and streaky materials were identified. Needle biopsy specimen from the pleura revealed anastomosing slit-like spaces lined by pleomorphic tumor cells. The tumor cells showed a strong reactivity for CD31 and vimentin and focal weak reactivity for factor VIII-related antigen.

• Journal of the Korean Geotechnical Society
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• v.21 no.9
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• pp.53-64
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• 2005

For geotechnical design in practice, soils are, in general, assumed to behave as a linear elastic or perfect plastic material. More realistic geotechnical design, however, should take into account various factors that affect soil behavior in the field, such as non-linearity of stress-strain response, stress history, and water content. In this study, a series of laboratory tests including triaxial and resonant column tests were peformed with sands of various silt contents, relative densities, stress states, OCR and water contents. This aims at investigating effects of various factors that affect strength and stiffness of sands. From the results in this study, it is found that the effect of OCR is significant for the intermediate stress-strain range from the initial to failure, while it may be ignored for the initial stiffness and peak strength. For the effect of water content, it is observed that the initial elastic modulus decreases with increasing water content at lower confining stress and relative density At higher confining stresses, the effect of water content Is found to become small.