• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.311-311
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• 2000

We propose a DP-based formulation for matching line patterns by defining a robust and stable geometric representation that is based on the conceptual organizations. Usually, the endpoint proximity and collinearity of image lines, as two main conceptual organization groups, are useful cues to match the model shape in the scene. As the endpoint proximity, we detect junctions from image lines. We then search for junction groups by using geometric constraint between the junctions. A junction chain similar to the model chain is searched in the scene, based on a local comparison. A Dynamic Programming-based search algorithm reduces the time complexity for the search of the model chain in the scene. Our system can find a reasonable matching, although there exist severely distorted objects in the scene. We demonstrate the feasibility of the DP-based matching method using both synthetic and real images.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2002.05a
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• pp.205-208
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• 2002

The vericut is one of the best CAM application for manufacturing data verification system. It is much applied in most manufacturing company for checking the manufacturing work. Using it a off-line manufacturing system is connected for on-line working on local area network. First, we choose the serial communication to chain an off-line manufacturing system and a personal computer which link with the server running the vericut.

• The KIPS Transactions:PartB
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• v.14B no.6
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• pp.453-460
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• 2007

In this paper, we present a method to extract the text lines in poorly structured documents. The text lines may have different orientations, considerably curved shapes, and there are possibly a few wide inter-word gaps in a text line. Those text lines can be found in posters, blocks of addresses, artistic documents. Our method based on the traditional perceptual grouping but we develop novel solutions to overcome the problems of insufficient seed points and vaned orientations un a single line. In this paper, we assume that text lines contained tone connected components, in which each connected components is a set of black pixels within a letter, or some touched letters. In our scheme, the connected components closer than an iteratively incremented threshold will make together a chain. Elongate chains are identified as the seed chains of lines. Then the seed chains are extended to the left and the right regarding the local orientations. The local orientations will be reevaluated at each side of the chains when it is extended. By this process, all text lines are finally constructed. The proposed method is good for extraction of the considerably curved text lines from logos and slogans in our experiment; 98% and 94% for the straight-line extraction and the curved-line extraction, respectively.

• Journal of Institute of Control, Robotics and Systems
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• v.21 no.3
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• pp.250-256
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• 2015

We present a novel method to model the body posture of a worm for vision-based automatic monitoring and analysis. The worm considered in this study is a Caenorhabditis elegans (C. elegans), which is popularly used for research in biological science and engineering. We model the posture by an open chain of a few curved or rigid line segments, in contrast to previously published approaches wherein a large number of small rigid elements are connected for the modeling. Each link segment is represented by only two parameters: an arc angle and an arc length for a curved segment, or an orientation angle and a link length for a straight line segment. Links in the proposed method can be readily related using the Denavit-Hartenberg convention due to similarities to the kinematics of an articulated manipulator. Our method was tested with real worm images, and accurate results were obtained.

• CELLMED
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• v.6 no.3
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• pp.16.1-16.5
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• 2016

Thymic stromal lymphopoietin (TSLP) is a novel interleukin (IL)-7-like cytokine and was originally discovered in the supernatant of a murine thymic stromal cell line. TSLP signal initiates via complex of the TSLP receptor and the IL-7 receptor α chain. TSLP expression is closely connected with many diseases such as atopic dermatitis, allergic rhinitis, asthma, inflammatory arthritis, eosinophilic esophagitis, rheumatoid arthritis, inflammatory bowel diseases, and cancer. In this review, I discussed biological roles of TSLP on mast cell-mediated allergic responses. In addition, this review summarizes the effective drugs in allergic-inflammatory reactions induced by TSLP on mast cells.

• IMMUNE NETWORK
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• v.12 no.1
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• pp.33-39
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• 2012

Background: Therapeutic approaches using monoclonal antibodies (mAbs) against complement regulatory proteins (CRPs:i.e.,CD46,CD55 and CD59) have been reported for adjuvant cancer therapy. In this study, we generated a recombinant 1E8 single-chain anti-CD59 antibody (scFv-Fc) and tested anti-cancer effect.by using complement dependent cytotoxicity (CDC). Methods: We isolated mRNA from 1E8 hybridoma cells and amplified the variable regions of the heavy chain (VH) and light chain (VL) genes using reversetranscriptase polymerase chain reaction (RT-PCR). Using a linker, the amplified sequences for the heavy and light chains were each connected to the sequence for a single polypeptide chain that was designed to be expressed. The VL and VH fragments were cloned into the pOptiVEC-TOPO vector that contained the human CH2-CH3 fragment. Then, 293T cells were transfected with the 1E8 single-chain Fv-Fc (scFv-Fc) constructs. CD59 expression was evaluated in the prostate cancer cell lines using flow cytometry. The enhancement of CDC effect by mouse 1E8 and 1E8 scFv-Fc were evaluated using a cytotoxicity assay. Results: The scFv-Fc constructs were expressed by the transfected 293T cells and secreted into the culture medium. The immunoreactivity of the secreted scFv-Fc construct was similar to that of the mouse 1E8 for CCRF-CEM cells. The molecular masses of 1E8 scFv-Fc were about 120 kDa and 55 kDa under reducing and non-reducing conditions, respectively. The DNA sequence of 1E8 scFv-Fc was obtained and presented. CD59 was highly expressed by the prostate cancer cell line. The recombinant 1E8 scFv-Fc mAb revealed significantly enhanced CDC effect similar with mouse 1E8 for prostate cancer cells. Conclusion: A 1E8 scFv-Fc construct for adjuvant cancer therapy was developed.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.4
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• pp.27-34
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• 2016

In the train system, railway vehicles are connected in a line. Therefore, this feature should be considered in composing network topology in a train system. Besides, inter-car communication should be distinguished from in-car communication. As for the inter-car communication, the hybrid topology was proposed to use rather than the conventional ring, star, daisy-chain, and bus topologies. In the hybrid topology, a number of cars are bound to be a group. Then star topology is used for the communication in a group and daisy-chain topology is used for the communication between groups. Hybrid topology takes the virtue of both star and daisy-chain topologies. Hence it maintains communication speed with reducing the number of connecting cables between cars. Therefore, it is important to choose the number of cars in a group to obtain higher performance. In this paper, we focus on the optimization of hybrid topology for railway cars. We first assume that the size of data and the frequency of data production for each car is identical. We also assume that the importance for the maximum number of cables to connect cars is variable as well as the importance of the communication speed. Separated weights are granted to both importance and we derive the optimum number of cars in a group for various number of cars and weights.

• Korean Chemical Engineering Research
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• v.45 no.5
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• pp.466-472
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• 2007

A technology platform for wafer-level three-dimensional integration circuits (3D-ICs) is presented, and that uses wafer bonding with low-k polymeric adhesives and Cu damascene inter-wafer interconnects. In this work, one of such technical platforms is explained and characterized using a test vehicle of inter-wafer 3D via-chain structures. Electrical and mechanical characterizations of the structure are performed using continuously connected 3D via-chains. Evaluation results of the wafer bonding, which is a necessary process for stacking the wafers and uses low-k dielectrics as polymeric adhesive, are also presented through the wafer bonding between a glass wafer and a silicon wafer. After wafer bonding, three evaluations are conducted; (1) the fraction of bonded area is measured through the optical inspection, (2) the qualitative bond strength test to inspect the separation of the bonded wafers is taken by a razor blade, and (3) the quantitative bond strength is measured by a four point bending. To date, benzocyclobutene (BCB), $Flare^{TM}$, methylsilsesquioxane (MSSQ) and parylene-N were considered as bonding adhesives. Of the candidates, BCB and $Flare^{TM}$ were determined as adhesives after screening tests. By comparing BCB and $Flare^{TM}$, it was deduced that BCB is better as a baseline adhesive. It was because although wafer pairs bonded using $Flare^{TM}$ has a higher bond strength than those using BCB, wafer pairs bonded using BCB is still higher than that at the interface between Cu and porous low-k interlevel dielectrics (ILD), indicating almost 100% of bonded area routinely.