• Title/Summary/Keyword: Conformal

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Estimated Risk of Radiation Induced Contra Lateral Breast Cancer Following Chest Wall Irradiation by Conformal Wedge Field and Forward Intensity Modulated Radiotherapy Technique for Post-Mastectomy Breast Cancer Patients

  • Athiyaman, Hemalatha;M, Athiyaman;Chougule, Arun;Kumar, HS
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.12
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    • pp.5107-5111
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    • 2016
  • Background: Epidemiological studies have indicated an increasing incidence of radiation induced secondary cancer (SC) in breast cancer patients after radiotherapy (RT), most commonly in the contra-lateral breast (CLB). The present study was conducted to estimate the SC risk in the CLB following 3D conformal radiotherapy techniques (3DCRT) including wedge field and forward intensity modulated radiotherapy (fIMRT) based on the organ equivalent dose (OED). Material and Methods: RT plans treating the chest wall with conformal wedge field and fIMRT plans were created for 30 breast cancer patients. The risks of radiation induced cancer were estimated for the CLB using dose-response models: a linear model, a linear-plateau model and a bell-shaped model with full dose response accounting for fractionated RT on the basis of OED. Results: The plans were found to be ranked quite differently according to the choice of model; calculations based on a linear dose response model fIMRT predict statistically significant lower risk compared to the enhanced dynamic wedge (EDW) technique (p-0.0089) and a non-significant difference between fIMRT and physical wedge (PW) techniques (p-0.054). The widely used plateau dose response model based estimation showed significantly lower SC risk associated with fIMRT technique compared to both wedge field techniques (fIMRT vs EDW p-0.013, fIMRT vs PW p-0.04). The full dose response model showed a non-significant difference between all three techniques in the view of second CLB cancer. Finally the bell shaped model predicted interestingly that PW is associated with significantly higher risk compared to both fIMRT and EDW techniques (fIMRT vs PW p-0.0003, EDW vs PW p-0.0032). Conclusion: In conclusion, the SC risk estimations of the CLB revealed that there is a clear relation between risk associated with wedge field and fIMRT technique depending on the choice of model selected for risk comparison.

Modeling of Cooling Channels of Injection Mould using Functionally Graded Material (기능성 경사 복합재를 이용한 사출금형의 냉각회로 모델링)

  • Shin, Ki-Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.35 no.12
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    • pp.1647-1653
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    • 2011
  • The cycle time in injection moulding greatly depends on the cooling time of the plastic part that is controlled by cooling channels. Cooling channels are required to facilitate the heat transfer rate from the die to the coolant without reducing the strength of the die. Employing layered manufacturing techniques (LMT), a die embedding conformal cooling channels can be fabricated directly while conventional cooling channels are usually made of straight drilled hole. Meanwhile, H13 tool steel is widely used as the die material because of its high thermal resistance and dimensional stability. However, H13 with a low thermal conductivity is not efficient for certain part geometries. In this context, the use of functionally graded materials (FGMs) between H13 and copper may circumvent a tradeoff between the strength and the heat transfer rate. This paper presents a method for modeling of conformal cooling channels made of FGMs.

Benefit of volumetric-modulated arc therapy over three-dimensional conformal radiotherapy for stage I-II extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue in the stomach: a dosimetric comparison

  • Chung, Joo-Hyun;Na, Kyoungsu;Kim, Il Han
    • Radiation Oncology Journal
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    • v.36 no.4
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    • pp.332-340
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    • 2018
  • Purpose: To retrospectively analyze dosimetric parameters of volumetric-modulated arc therapy (VMAT) and three-dimensional conformal radiotherapy (3D-CRT) delivered to extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue in the stomach (gastric MALT lymphoma) to find out advantages of VMAT and conditions for definite benefits of VMAT. Materials and Methods: Fifty patients with stage I-II gastric MALT lymphoma received VMAT (n = 14) or 3D-CRT (n = 36) between December 2005 and April 2018. Twenty-seven patients were categorized according to whether the planning target volume (PTV) overlaps kidney(s). Dosimetric parameters were analyzed by dose-volume histogram. Results: Radiation dose to the liver was definitely lower with VMAT in terms of mean dose (p = 0.026) and V15 (p = 0.008). The V15 of the left kidney was lower with VMAT (p = 0.065). For those with PTV overlapping kidney(s), the left kidney V15 was significantly lower with VMAT. Furthermore, the closer the distance between the PTV and kidneys, the less the left kidney V15 with VMAT (p = 0.037). Delineation of kidney(s) by integrating all respiratory phases had no additional benefit. Conclusions: VMAT significantly increased monitor units, reduced treatment time and radiation dose to the liver and kidneys. The benefit of VMAT was definite in reducing the left kidney V15, especially in geometrically challenging conditions of overlap or close separation between PTV and kidney(s).

Analysis of Shielded Microstrip Line with Ground Aperture using Conformal Mapping Method (등각사상 법을 이용한 접지 면에 어퍼처를 갖는 차폐된 마이크로스트립 선로 해석)

  • Chun Dong-Wan;Lee Jin-Taek;Kim Won-Ki;Shin Chull-Chai
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.10 s.89
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    • pp.944-951
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    • 2004
  • In this paper, we proposed the method of the characteristic impedance and effective dielectric constant calculations of the shielded microstrip line with ground aperture using conformal mapping method. This method has advantages that can calculate the transmission parameters without using any other numerical method because present the closed form equations. First of all, we supposed the signal propagate with the microstrip mode(Quasi-TEM) and calculated the capacitance divide by three sections and calculated the characteristic impedance and effective dielectric constant using calculated capacitances. From the HFSS simulation result, calculated result was very similar to the simulation result within the five percent error range.

A Study on Improvement of Wegmann's method by Low Frequency pass Filter (저주파 필터를 이용한 Wegmann 방법의 개량에 관한 연구)

  • Song, Eun-Jee
    • The KIPS Transactions:PartA
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    • v.8A no.4
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    • pp.503-508
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    • 2001
  • Conformal mapping is useful to solve problems in heat conduction, electrostatic potential and fluid flow involving Laplace's equation in two independent variables. Determinations of conformal maps from the unit disk onto a Jordan region eventually requires solving the Theodorsen equation which is in general nonlinear with respect to the boundary correspondence function. H bner's method which has been well known for the efficient method among the many suggestions for the Theodorsen equation, was improved in early study[1, 2]. In this paper Wegmann's method is treated that is more efficient in computation cost rather than H bner's. But we found that a question which is divergent in some difficult problems by numerical experiment of Wegmann's iteration. We analyze theoretically the cause of divergence and propose an improved method by applying a low frequency filter to the Wegmann's method. Numerical experiments by our improved method show convergence for all divergent problems by Wegmann's method.

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A Comparison between Three Dimensional Radiation Therapy and Intensity Modulated Radiation Therapy on Prostate Cancer (전립샘암의 방사선 치료 시 입체조형치료법와 세기조절방사선 치료법의 비교)

  • Kim, YoungJae;Lee, JaeSub;Hong, Seongill;Ko, HyeJin
    • Journal of the Korean Society of Radiology
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    • v.7 no.6
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    • pp.409-414
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    • 2013
  • In this study, we evaluated to the superiority of treatment techniques on prostate cancer, apply to each other treatment techniques-3D conformal therapy versus IMRT-using dose distribution and dose coverages. Obtained 10 patients CT simulation, divided tumor volume and critical organs. Prescription dose was 80 Gy on tumor volume and Each of plans was set by two different plans. As a result, Dose coverage was superior to IMRT. The IMRT's tumor absorbed dose(100.2%) was close to prescription doses. Normal tissue(bladder, rectal, bowel Lt Rt fumoral head) absorbed dose rate was superior. In other words, the radiation therapy of prostate cancer with intensity modulated radiation therapy was better than conformal radiation therapy on dose.

Improvement for Shielding Effectiveness of EMI Shield Layers using Conformal Spray Coating Scheme (콘포멀 스프레이 코팅으로 형성한 EMI 차단막의 차폐효과 개선)

  • Hur, Jung;Lee, Won-Hui
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.18 no.6
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    • pp.107-112
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    • 2018
  • Shielding effectiveness (SE) improvement with EMI shield layers fabricated by conformal spray coating system was studied. Silver or Nickel powder filled acrylic resin were sprayed on the samples. We compared the performance with the viscosity of 400 cPs and 100 cPs cases. The thickness range of the coating layer was 20 to 50 um for the silver, 60 to 120 um for the nickel. The shielding effectiveness was measured by ASTM D4935 using coaxial type TEM-cell. The silver-filled resin showed much better performance than that of the nickel-filled resin. The shielding effectiveness increased almost proportional to the thickness of the coating layers until being saturated around 63 dB for the silver-layer or around 34 dB for the nickel-layer. The best performance measured in this study was the shielding effectiveness of 63 dB with $35{\mu}m-thick$ of silver-layer.

Development of VHF-Band Conformal Antenna for UAV Mounting (무인기 탑재용 VHF 대역 형상적응형 안테나 개발)

  • Euntae Jung;Juhyun Lee;Jinwoo Park;Byunggil Yu;Kichul Kim;Jaesoo Jung
    • Journal of the Korea Institute of Military Science and Technology
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    • v.26 no.1
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    • pp.54-63
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    • 2023
  • In this paper, a VHF band conformal antenna for UAV mounting was developed. The proposed antenna was designed as an shape-adaptive structure by minimizing the antenna height to be advantageous in RCS reduction performance. As for the antenna radiator, the outer radiator was arranged around the inner radiator to apply the CRLH zeroth-order resonance structure. With this structure, the height of the antenna was minimized, and it was reduced by about 70 % compared to the existing blade antenna. In addition, for impedance matching, the intermediate frequency bandwidth of the VHF band was improved through the sleeve pin of the inner radiator, and the low frequency bandwidth of the VHF band was improved by applying an EMI shielding gasket to the shorting pin of the outer radiator. The proposed antenna was manufactured and measured to verify the performance of the device and the performance after UAV mounting. As a result, the standard was satisfied for the operating frequency.

Study on Tumor Control Probability and Normal Tissue Complication Probability in 3D Conformal Radiotherapy (방사선 입체조형치료에 대한 종양치유확율과 정상조직손상확율에 관한 연구)

  • 추성실
    • Progress in Medical Physics
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    • v.9 no.4
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    • pp.227-245
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    • 1998
  • A most appropriate model of 3-D conformal radiotherapy has been induced by clinical evaluation and animal study, and therapeutic gains were evaluated by numerical equation of tumor control probability(TCP) and normal tissue complication probability (NTCP). The radiation dose to the tumor and the adjacent normal organs was accurately evaluated and compared using the dose volume histogram(DVH). The TCP and NTCP was derived from the distribution of given dosage and irradiated volume, and these numbers were used as the biological index for the assessment of the treatment effects. Ten patients with liver disease have been evaluated and 3 dogs were sacrificed for this study. Based on the 3-D images of the tumor and adjacent organs, the optimum radiation dose and the projection direction which could maximize the radiation effect while minimizing the effects to the adjacent organs could be decided. 3). The most effective collimation for the normal adjacent organs was made through the beams eye view with the use of multileaf collimator. When the dose was increased from 50Gy to 70Gy, the TCP for the conventional 2-port radiation and the 5-port multidimensional therapy was 0.982 and 0.995 respectively, while the NTCP was 0.725 and 0.142 respectively, suggesting that the 3-D conformal radiotherapy might be the appropriate therapy to apply sufficient radiation dose to the tumor while minimizing the damages to the normal areas of the liver. Positive correlation was observed between the NTCP and the actual complication of the normal liver in the animal study. The present study suggest that the use of 3-D conformal radiotherapy and the application of the mathematical models of TCP and NTCP may provide the improvements in the treatment of hepatoma with enhanced results.

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Clinical Application of 3-D Conformal Radiotherapy for Carcinoma of the Ethmoid Sinus : I. Comparative Analysis Between Conventional 2-D and 3-D Conformal Plans (사골동 종양의 3-차원 입체조형치료 : I. 2차원 치료계획과 3차원 치료계획의 비교분석)

  • Lee Sangwook;Kim Gwi Eon;Keum Ki Chang;Park Hee Chul;Cho Jae Ho;Han Soung Uk;Lee Kang Kyu;Suh Chang Ok;Hong Won Pyo;Park In Yong
    • Radiation Oncology Journal
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    • v.15 no.4
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    • pp.287-296
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    • 1997
  • Purpose : This is study of whether 3-D conformal radiotherapy for carcino-mas of the ethmoid sinus were better than those treated with conventional 2-D plan, Materials and Methods : The 3-D conformal treatment Plans were compared with conventional 2-D plans in 4 patients with malignancy of the ethmoid sinus. Isodose distribution, dose statistics, and dose volume histogram of the planning target volume were used to evaluate differences between 2-D and 3-D plans. In addition. the risk of radiation exposure of surrounding normal critical organs are evaluated by means of point dose calculation and dose volume histogram. Results : 3-D conformal treatment plans for each patient that the better tumor coverages by the planning target volume with improved dose homo-geneity, compared to 2-D conventional treatment Plans in the same Patient. On the other hand, the radiation dose distributions to the surrounding nor-mal tissue organs, such as the orbit and optic nerves are not significantly reduced with our technique, but a substantial sparing in the brain stem and optic chiasm for each patient. Conclusion : Our findings represented the potential advantage of 3-D treatment planning for dose homogeniety as well as sparing of the normal tissue surrounding the tumor. However, further investigational studies are required to define the clinical benefit.

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