• Title/Summary/Keyword: Confidence Value

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Lack of Assocation of Glutathione S-transferase T1 Gene Null and Susceptibility to Lung Cancer in China: a Meta-analysis

  • Liu, Hong-Zhou;Peng, Jie;Zheng, Fang;Wang, Chun-Hong;Han, Ming-Jun
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7215-7219
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    • 2013
  • Background: Variation in metabolic genes is regarded as an important factor in processes leading to cancer. However, the effect of GSTT1 null genotype is divergent in the form of lung cancer. Methods: Studies were conducted at different research databases from 1990 to 2013 and the total odds ratio (OR) and 95% confidence interval (CI) were calculated for lung cancer. Review Manager 5.2 and STATE 12 are employed. Results: Total OR value is calculated from 17 articles with 2,118 cases and 2,915 controls. We discovered no significant increase in lung cancer risk among subjects carrying GSTT1 null genotype [OR = 1.15; 95% CI 0.97-1.36] in this meta-analysis. Conclusion: The GSTT1 deletion polymorphism does not have a significant effect on the susceptibility to lung cancer overall in China.

Prediction of the shelf-life of ammunition by time series analysis (시계열분석을 적용한 저장탄약수명 예측 기법 연구 - 추진장약의 안정제함량 변화를 중심으로 -)

  • Lee, Jung-Woo;Kim, Hee-Bo;Kim, Young-In;Hong, Yoon-Gee
    • Journal of the military operations research society of Korea
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    • v.37 no.1
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    • pp.39-48
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    • 2011
  • To predict the shelf-life of ammunition stockpiled in intermediate have practical meaning as a core value of combat support. This research is to Predict the shelf-life of ammunition by applying time series analysis based on report from ASRP of the 155mm, KD541 performed for 6 years. This study applied time series analysis using 'Mini-tab program' to measure the amount of stabilizer as time passes by is different from the other one that uses regression analysis. The average shelf-life of KD541 drawn by time series analysis was 43 years and the lowest shelf-life assessed on the 95% confidence level was 35 years.

Kinetics and Modelling of Cell Growth and Substrate Uptake in Centella asiatica Cell Culture

  • Omar, Rozita;Abdullah, M.A.;Hasan, M.A.;Rosfarizan, M.;Marziah, M.
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.3
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    • pp.223-229
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    • 2006
  • In this study, we have conducted kinetics and modelling studies of Centella asiatica cell growth and substrate uptake, in an attempt to evaluate cell growth for a better understanding and control of the process. In our bioreactor cultivation experiment, we observed a growth rate of 0.18/day, a value only 20% higher than was seen in the shake flask cultivation trial. However, the observed maximum cell dry weight in the shake flask, 10.5g/L, was 14% higher than was achieved in the bioreactor. Ninety seven percentage confidence was achieved via the fitting of three unstructured growth models; the Monod, Logistic, and Gompertz equations, to the cell growth data. The Monod equation adequately described cell growth in both cultures. The specific growth rate, however, was not effectively predicted with the Logistic and Gompertz equations, which resulted in deviations of up to 73 and 393%, respectively. These deviations in the Logistic and Gompertz models may be attributable to the fact that these models were developed for substrate-independent growth and fungi growth, respectively.

The Effect of Using Graphing Calculators on Students' Understanding Functions and Attitudes Towards Mathematics and Graphing Calculators

  • Kwon, Oh-Nam;Kim, Min-Kyeong
    • Research in Mathematical Education
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    • v.4 no.1
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    • pp.1-22
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    • 2000
  • The purpose of this study was to investigate the effects of using graphing calculators on students' understanding of the linear and quadratic function concepts. The populators of this study are tenth graders at high school in Seoul, one class for the treatment group and another class for the comparison group, and experiment period is 14 weeks including two weeks for school regular exams.Function tests used in the study was proposed which described a conceptual knowledge of functions in terms of the following components: a) Conceptual understanding, b) Interpreting a function in terms of a verbal experission, c) Translating between different representations of functions, and d) Mathematical modeling a real-world situation using functions. Even though the group test means of the individual components of conceptual understanding, interpreting, translating, mathematical modeling did not differ significantly, there is evidence that the two groups differed in their performance on conceptual understanding. It was shown that students learned algebra using graphing calculators view graphs more globally. The attitude survey assessed students' attitudes and perceptions about the value of mathematics, the usefulness of graphs in mathematics, mathematical confidence, mathematics anxiety, and their feelings about calculators. The overall t-test was not statistically significant, but the students in the treatment group showed significantly different levels of anxiety toward mathematics.

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The Concept Analysis of Motherhood (간호이론개발을 위한 개념 분석 : 어머니됨)

  • Kim, Young-Hee
    • Women's Health Nursing
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    • v.4 no.2
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    • pp.245-257
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    • 1998
  • The characteristics of health behavior related pregnancy and childbirth have reflected on the cultural belief and value in the society. The efforts for women's health promotion through the current illumination of the traditional health care are the prompting assignment to be in nursing. The process of motherhood already progress before the motherhood actually. The functional state as the expectant mother can be the important predicting factor of the postpartum state, the quality of a married life. Motherhood was analyzed by Walker and Avant's method to clarify the concept 'to be a mother' using the various concepts like Koreans' Taekyo, transition to motherhood, maternal identity, maternal role attainment, maternal fetal attachment, and maternal fetal interaction. Upon the concept analysis, naturalness, responsibility, attachment, readiness, controllability were identified as the defining characteristics of motherhood. The antecedents of motherhood were consist of maternal affection, positive self esteem, pregnancy acceptance, fetus recognition and the consequences of motherhood were consist of positive maternal identity, maternal fetal attachment, confidence about the maternal role, the healthy mother and the healthy baby. The empirical referents of motherhood were consists of recognition of motherhood, expectation about motherhood, fetal recognition with ultrasonography and fetal movement, experience of unification between mother and fetus, expression of affection to the fetus, concern about fetal health, concern and practice about Taekyo, adaptation behavior about physical change and discomfort due to pregnancy. Therefore it is necessary to develop the instruction program of motherhood including the defining attributes identified in this study.

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Data processing of sensor output for correction of pressure measurement value of an anesthesia ventilator (마취기용 인공호흡기의 압력 측정값의 보정을 위한 센서 출력의 데이터 처리)

  • 박영준;이종수;김영길
    • Proceedings of the IEEK Conference
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    • 1999.11a
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    • pp.1067-1070
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    • 1999
  • Anesthesia gas to pour to patients affects the flow and volume as the pressure difference of an oxygen and an anesthesia gas. An anesthesia gas, being injurious and polluting an environment, must control the pressure of an oxygen gas because of being used by closing up tight. But a pressure sensor to use for measuring an oxygen gas appears other pressure as the characteristic and the error difference of elements to use for implementing an system. A medical machine such as an anesthesia ventilator must be accurate because of using for the person's body. So we intend to implement an system for a sensor pressure measurement not to be change regardless of an environment. This papers is the target that a sensor pressrue measurement to be changed in environment is equal to actual sensor pressure measurement. So an implemented system is using analog filter and digital filter to reduce a noise. And we are using auto-zeroing and calibration to correct a sensor pressure which is changed in environment. Through such a process we increase the accuracy and the confidence of an anesthesia ventilator by controlling the flow of an anesthesia gas.

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Driving Behavior Characteristic Analysis of an Older Driver on a Driving Simulator (운전 시뮬레이터를 이용한 고령자의 운전행동 특성 분석)

  • Min, Byung-Chan;Min, Yoon-Ki;Kim, Young-Sun;Lee, Beum-Soo;Kim, Young-Su;Min, Su-Young;Kim, Bo-Seong;Kang, Jin-Kyu
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.32 no.1
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    • pp.67-71
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    • 2009
  • Using driving simulator, we analyzed the driving behavior of an older driver on intersection and measured the pychological load to HRV. As a results, older drivers started to enter the more complex intersection on a great distance and on low velocity for safety driving. On the other hand, the value of HRV would be lower on more complex intersections. It suggested that an older driver allowed for his own losses of physiological and cognitive function and recognized low level of driving confidence relatively.

Hot Leg Temperature Uncertainty due to Thermal Stratification

  • Jang, Ho-Cheol;Ju, Kyong-In;Kim, Young-Bo;Sul, Young-Sil;Cheong, Jong-Sik
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05b
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    • pp.29-35
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    • 1996
  • For the Reactor Coolant System(RCS) flow rate measurement by the secondary calorimetric heat balance method, the coolant temperature of the hot leg is needed. Several Resistance Temperature Detectors(RTD) are installed in the hot leg to measure the temperature, but the average value of RTDs does not correctly represent the energy-averaged(bulk) temperature because of the thermal stratification phenomenon. Therefore some correction is introduced to predict the bulk temperature, but the correction inevitably contains uncertainty because the stratification is not defined well quantitatively yet. Therefore a large uncertainty for the correction has been used for the conservative estimation. But unrealistically large uncertainty causes degradation of the measurement method and yields difficulty to meet the acceptance criterion in start-up flow measurement test. In this paper, an analytical estimation is made on the correction and the related uncertainty using the measured hot leg velocity profile of System 80 reactor flow model test and the measured temperatures of YGN 3&4 and PVNGS 1&2 start-up tests. The results reveal that the magnitude of the correction uncertainty is much smaller than that used in the previous design. Therefore, the confidence on the flow rate measurement method can be improved and the difficulty in start-up flow measurement test can be lessened if the smaller correction uncertainty obtained through this estimation is applied.

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Use of Na+/K+ATPase in Maceobrachium nipponnese as a biomaker of lead pollution in aquatic ecosystem (수서생태계 납오염에 대한 생체지표로서 Maceobrachium nipponnese내 Na+/K+ATPase의 활용)

  • Chung, Myung-Kiu;Kim, Hak-Hee
    • Journal of Korean Society on Water Environment
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    • v.18 no.4
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    • pp.395-400
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    • 2002
  • Lead is one of the most toxic metal and is detectable in practically all phases of environment and in all biological system. Transport, industrial and domestic waste products are the main sources of this pollutant. Ingested lead is rapidly absorbed and widely distributed throughout the body, causing extensive tissue damage. In this study, we chose the freshwater decapods Maceobrachium nipponnese as a sensitive indicator organism for environmental pollution. In order to investigate the possibility in use of $Na^+/K^+ATPase$ activity as a biomarker of lead pollution, we tested the acute toxicity of lead to Maceobrachium nipponnese. The $LC_{50}(96hr)$ value for lead in Maceobrachium nipponnese was found to be $446{\mu}g/L$ with the 95% confidence limits. The lead exposure group at $LC_{50}$ showed a significant $Na^+/K^+ATPase$ inhibition, depending on the exposure time. Comparision of several concentrations of lead revealed that the $Na^+/K^+ATPase$ activity in Maceobrachium nipponnese was significantly decreased in a concentration dependent manner. These results suggest that $Na^+/K^+ATPase$ activity in Maceobrachium nipponnese may possibly be used as a biomarker of lead pollution in aquatic ecosystem.

Determination of Proper Probability Distribution for Groundwater Monitoring Stations in Jeju Island (제주도 지하수위 관측지점별 적정 확률분포형의 결정)

  • Chung, Il-Moon;Nam, Woosung;Kim, Min Gyu;Choi, Gian;Kim, Gee-Pyo;Park, Yun-Seok
    • Journal of Soil and Groundwater Environment
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    • v.23 no.1
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    • pp.41-53
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    • 2018
  • Comprehensive statistical analysis for the 127 groundwater monitoring stations in Jeju Island during 2005~2015 was carried out for the re-establishment of management groundwater level. Three probability distribution functions such as normal distibution, GEV (General Extreme Value) distribution, and Gumbel distribution were applied and the maximum likelihood method was used for parameter estimation of each distribution. AIC (Akaike information criterion) was calculated based on the estimated parameters to determine the proper probability distribution for all 127 stations. The results showed that normal distribution and Gumble distribution were found in 11 stations. Whereas GEV distribution were found in 105 stations, which covered most of groundwater monitoring stations. Therefore, confidence levels should be established in accord with the proper probability distribution when groundwater level management is determined.