• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.18.1-18.7
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• 2015

Background: The aim of this study is to develop a rat model of bisphosphonates-related osteonecrosis of the jaw (BRONJ) that would be verified with clinical, radiological and histological examination, and to confirm the influence of concurrent bisphosphonates and steroids use upon the occurrence and aggravation of BRONJ. Methods: Twenty seven rats were divided into 3 groups; Saline group (I), Zoledronate group (II), Zoledronate and Dexamethasone group (III). Rats got weekly intraperitoneal injection for 4 times and extraction of left maxillary and mandibular 1st, 2nd molars were followed. Consecutive injections were performed, and blood sampling for measurements of C-terminal crosslinked telopeptide of type I collagen and tartrate-resistant acid phosphate 5b rats were performed at the time of 2, 4 and 8 weeks. And then, rats were sacrificed and evaluated clinically, radiologically and histologically. Results: 12/18 (66.6 %) of experimental group were diagnosed as BRONJ. There was no significant difference in incidence between zoledronate alone group (ll) and concurrent use of zoledronate and dexamethasone group (lll). Conclusions: Concurrent use of bisphosphonates and steroids increase incidence of BRONJ compared to saline group (l). Zoledronate alone group (ll) and concurrent use of zoledronate and dexamethasone group (lll) shows same incidence of BRONJ. Based on this study, the rat treated with bisphosphonates and steroids can be considered a novel, reliable and reproducible model to understand pathology of BRONJ.

• 한국산학기술학회논문지
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• 제14권4호
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• pp.1555-1560
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• 2013

칼럼 타입의 전동조향장치(MDPS) 시스템은 차량 안전성과 연료 효율 향상을 보장하기에 승용차에 보편적으로 장착하고 있다. 시스템 해석과 제어기 개발을 위해서는 보통 Mechanical Simulation사에서 제작한 CarSim 프로그램과 매트랩 시뮬링크의 두 프로그램을 이용하여 제어 알고리즘과 차량 모델이 결합되어 하나의 시스템처럼 동시에 동작하도록 시뮬레이션을 수행한다. 매트랩 시뮬링크의 MDPS 제어 시스템과 완전 차량 모델의 동시시뮬레이션 기술개발에 대한 구체적이 방법이 소개된 적이 없기에 본 연구에서 상세히 소개하기로 한다. 본 연구에서는 사인 파형의 조향핸들입력을 이용한 시뮬레이션 결과가 보여 지고 실험결과와 잘 비교되었다. 이러한 동시시뮬레이션 기술은 차량의 핸들링 성능 평가나 CMDPS 평가 수행 및 로직 튜닝을 위해 효과적으로 사용될 수 있다.

• Journal of Biosystems Engineering
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• 제31권4호
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• pp.349-354
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• 2006

This study was performed to evaluate the performances for a concurrent flow rice dryer of pilot scale with devices for circulating rice. The pilot scale dryer with the capacity of 700 kg was developed to obtain design informations for the development of actual scale dryer of holding capacity of 10 tons. Three drying tests were conducted at two temperature levels of $100^{\circ}C\;and\;120^{\circ}C$, and two air flow rates levels of $28.5cmm/m^2\;and\;57.1cmm/m^2$. Drying conditions for Test-1, Test-2 and Test-3 were $100^{\circ}C\;-28.5cmm/m^2,\;120^{\circ}C-28.5cmm/m^2\;and\;120^{\circ}-57.1cmm/m^2}$ respectively. Drying rates were 0.73%(w.b./h) for Test-1, 0.90%(w.b./h) for Test-2 and 1.46%(w.b./h) for Test-3. The crack ratios of brown rice after drying ranged from 2.4% to 8.4%, and increased with the increase of drying rate and airflow rate. The energy consumptions were from 6,225 kJ/kg to 6,993 kJ/kg which was higher than that of conventional cross-flow rice circulating type dryer used in Korea. This results were due to the lower ambient air temperatures of $4.5^{\circ}C\;to\;13.4^{\circ}C$ during drying tests.

• 한국콘텐츠학회논문지
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• 제18권5호
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• pp.1-10
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• 2018

본 연구는 비즈니스용 웹 사이트 개발에 있어 비용효과적인 사용성 테스트 모델을 제시할 목적으로 수행되었다. 본 연구에서는 실시간 발성사고법(Concurrent Think Aloud), 성능 측정, 코칭 방법, 원격 테스트 방법을 혼합한 사용성 테스트 모델을 제시하였다. 테스트 대상은 연구진이 운영하는 전자정보 공동구매 컨소시엄 웹 사이트로 하였다. 테스트 참가자는 실제 사용자로 하였으며 업무 역할과 숙련도별로 차이를 두어 구성하였다. 사용성 테스트 분석 결과를 반영하여 시스템을 개선하였고, 동일한 태스크를 수행하여 소요시간과 마우스 궤적 복잡도를 비교한 결과 모든 참가자의 사용성이 개선된 것을 확인하였다. 본 연구에서 제시한 사용성 테스트 모델을 활용하여 비즈니스용 웹 사이트를 비용 효과적으로 평가하여 분석하는데 도움이 될 것으로 기대한다. 웹 사이트들은 목적별, 분야별로 특성이 있으므로 향후에는 특성화된 사용성 테스트 모델 연구가 필요하다고 본다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7371-7375
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• 2014

Background: Concurrent chemo-radiotherapy is the recommended standard treatment modality for patients with locally advanced lung cancer. The purpose of three-dimensional conformal radiotherapy (3DCRT) is to minimize normal tissue damage while a high dose can be delivered to the tumor. The most common dose limiting side effect of thoracic RT is radiation pneumonia (RP). In this study we evaluated the relationship between dose-volume histogram parameters and radiation pneumonitis. This study targeted prediction of the possible development of RP and evaluation of the relationship between dose-volume histogram (DVH) parameters and RP in patients undergoing 3DCRT. Materials and Methods: DVHs of 41 lung cancer patients treated with 3DCRT were evaluated with respect to the development of grade ${\geq}2$ RP by excluding gross tumor volume (GTV) and planned target volume (PTV) from total (TL) and ipsilateral (IPSI) lung volume. Results: Were admitted statistically significant for p<0.05. Conclusions: The cut-off values for V5, V13, V20, V30, V45 and the mean dose of TL-GTV; and V13, V20,V30 and the mean dose of TL-PTV were statistically significant for the development of Grade ${\geq}2$ RP. No statistically significant results related to the development of Grade ${\geq}2$ RP were observed for the ipsilateral lung and the evaluation of PTV volume. A controlled and careful evaluation of the dose-volume histograms is important to assess Grade ${\geq}2$ RP development of the lung cancer patients treated with concurrent chemo-radiotherapy. In the light of the obtained data it can be said that RP development may be avoided by the proper analysis of the dose volume histograms and the application of optimal treatment plans.

• 한국CDE학회논문집
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• 제1권3호
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• pp.203-214
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• 1996

An information sharing system, namely World Design View, is developed for browsing product design data on the World Wide Web environment. For the last few years information sharing has been rapidly emerging as an important research issue in the areas of concurrent engineering, product data management, virtual manufacturing, and so on. Since we are mainly concerned with product development, the key information that needs be communicated and shared is product data. The developed system puts the major advantages of STEP, OODB, and VRML together. The STEP standard provides a consistent data exchange format and application interfaces among different CAD/CAM systems. OODB is efficient and effective in dealing with complex data structures often found in engineering applications. Virtual worlds for 3-D product models can be created by VRML which is networked via the global Internet and hyperlinked with WWW. The World Design View system can support for members of virtual design teams, possibly distributed all over the world, to share 3-D shape information quickly and easily.

• 한국전자거래학회지
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• 제1권2호
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• pp.161-173
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• 1996

It Is a typical scenario in concurrent engineering/design that different perspectives of each team members participating In the project exist, and those perspectives lead to conflicting decisions. The model 'resolution network' proposed in this work provides system-mediated resolution for all related team engineers to consider to optimize the manufacture in general. This paper focuses on development of the general architecture of the model and a search engine called Mediator to determine a resolution network from a given constraint network. The Mediator manages the constraint network, determines the most optimistic resolution called optimal point in terms of satisfying overall production goal , and use the optimal point to mediate controversial issues among teams. The biggest merit of our model is that it provides teams with resolution with logical and rational reasoning.

• 소음진동
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• 제7권4호
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• pp.689-700
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• 1997

There are many difficulties in designing the engine structure properly due to the strong conflicts between NVH characteristics and the high performance, light weight and low product cost. Many feasible noise reduction techniques should be carefully incorporated to meet such stringent noise requirements. It is also required that the engine development be carried out by introducing concurrent engineering, in which the analysis and test database are usefully applied to the detail designs from the 1st stage. This paper reviews the significance of the noise characteristics of the structure elements in relation to the combustion pressure. The mechanisms of the crank shaft rumbling, which is the main source having the bad influence on the sound quality, are also explained. The influences of dynamic behavior of engine structure on its noise are investigated, followed by discussions on experimental results of the features necessary for the design of low noise engine concepts.

• 소성∙가공
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• 제24권5호
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• pp.317-322
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• 2015

A process for the concurrent welding and extruding of pipe was designed for continuous production of fin tubes. Unlike a conventional pipe extrusion, the new process is able to extrude a pipe continuously without limit of length by using spring type wire material. The current paper provides the basic research for welding during the extrusion using a spring type wire material. The object of the current study is to investigate the possibility that the spring type wire material could be extrude into a welded pipe. The appropriate extrusion ratio was selected through investigation of loads using computer simulations. As a result, experiments showed that pipe could be welded and simultaneously extruded with spring type wire material of aluminum. The tensile strength of the welded and extruded aluminum pipe can reach 80% of tensile strength of original aluminum feedstock.

• 대한가정학회지
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• 제35권2호
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• pp.187-199
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• 1997

The purposes of this research were to investigate the conditions of family life education and to develop an effective program for single-mother families. to study these objectives, two kinds of questionnaire were used and the data were obtained through 60 officials and 173 single mothers. the most frequently educated topic by organizations was counseling and mental hygiene. Family relationships and women's activity were following important topics, but family relationships was most needed topic by officials and single mothers. Concurrent education type for mother and children was more preferred and its appraisal was relatively high. for effectiveness in education, single mothers and officials both demanded more practical and easy understandable contents. According to above results, the concurrent-type program for strong mother-children relationships that emphasized communication skills, psychological strategies, and the importance of social support system was proposed.