• 대한핵의학회지
• /
• 제23권2호
• /
• pp.195-200
• /
• 1989

The authors studied to evaluate the difference of the diagnostic performance between reading from digital image on the video CRT of PACS (Picture Archiving and Communication System) and from analogue image of conventional film mode. We compared interpretative accuracy of above two reading modes by having two observers read a series of liver scintigrams. Images were read once from film and a second time from video CRT of elementary PACS. The concordance rate of interpretation of the two modes was in the range from 61.0% to 93.2%. The diagnostic accuracies of digital image reading and analogue image reading were 72.9% and 74.6% respectively in one observer, and 72.9% and 76.3% in another one. No significant difference in interpretative accuracy could be found between two modes of reading.

• 한국식생활문화학회지
• /
• 제33권2호
• /
• pp.186-198
• /
• 2018

The Sasang constitution typology was analyzed through SCAT2 and a specialist to examine the correlation between the Sasang constitution and dietary pattern, and the difference in BMI and food preference according to Sasang constitution was determined. The Sasang constitution typology of the subjects was classified by SCAT2 and a specialist. Seventy-four subjects were screened by SCAT2 (SC), and 18 of them were judged by the specialist (SP). The results of SCAT2 and the specialist were consistent in 13 subjects (SS). BMI and food preference among these groups were compared. The concordance rate of SCAT2 and the specialist classification was 72.2%. The BMI in SC was significantly lower in the order of Taeeumin, Soyangin, and Soeumin, but no significant difference was observed between Taeeumin and Soyangin in SP and SS. To analyze the preference of food and the constitutional suitability, the 'Yin-Yang food preference index' was developed and compared with the data classified by constitutional food according to existing ideological medical theory. As a result, there were 33 food items that matched in the SP-SS, which was more than that in the SC-SP (4 items), SC-SS (6 items), and SC-SP-SS (4 items). Twenty-four of the 33 matched food items were consistent with the existing constitutional food data. In conclusion, SCAT2 is a very useful tool for Sasang constitutional research, but for more objective research, it is recommended that subjects who show consistent results by different methods be targeted.

• Journal of Gastric Cancer
• /
• 제10권4호
• /
• pp.175-181
• /
• 2010

Purpose: There is controversy over the treatment for low grade dysplasia, while resection is recommended for high grade dysplasia. But the concordance of the grade of dysplasia between pre- and post-resection is low because of sampling errors with endoscopic biopsy. We attempted to establish a clearer direction for the treatment of dysplasia by clarifying the discrepancy between the pre- and postresection diagnoses. Materials and Methods: We performed a retrospective review of 126 patients who had undergone resection with the diagnosis of dysplasia on biopsy at Bundang CHA Hospital from 1999 to 2009. Results: Seventy patients were diagnosed with low grade dysplasia and 56 patients were diagnosed with high grade dysplasia. Among the 33 patients who received gastrectomy with lymph node dissec-tion, 30 patients were revealed to have invasive cancers and 4 patients showed lymph node metastasis. Discordance between the diagnoses from biopsy and resection occurred in 55 patients (44%). There was no correlation on the comparative analysis between the size, location or gross type of lesion and the grade of dysplasia. Conclusions: The rate of discordance between the diagnoses of endoscopic biopsy and the post resection pathologic report was as high as 44%. Endoscopic mucosal resection was not sufficient for some patients who were diagnosed with dysplasia on biopsy due to the presence of lymph node metastasis. It is necessary to be prudent when determining the follow-up and treatment based solely on the result of the biopsy.

• 한국학교보건학회지
• /
• 제22권1호
• /
• pp.61-65
• /
• 2009

AIMS: Korean National Growth Chart was newly developed at 2007. Prevalence of obesity is expected to be changed according to reference data. This study was performed to compare the prevalence of obesity based on the newly developed growth curve with that of previous data. We also investigate the incidence of obesity, overweight, and normal criteria by two kinds of growth curves. Method: We obtained weight, height from 438 middle school students and 1786 high school students. We divided enrolled students into four groups (middle school boys, middle school girls, high school boys, high school girls). The obese, over weight group was defined as BMI(body mass index) more than 95th, 85th${\sim}$94th percentile respectively for age and sex. Obesity by relative weight was defined more than 20% of ideal body weight. We compare the prevalence of obesity in each group by the newly developed Korean National Growth Chart in 2007 and that in 1998. Result: Prevalence of obesity by BMI based on 2007 Korean National Growth Chart and that in 1998 were 8.2-12.9% and 9.0-20.4% respectively. The concordance rate were 99.0%-100% in obese group and 45.0%-91.9% in overweight group according to two kinds of reference data. Prevalence of obesity by relative weight was 11.7-23.0% that was same between 2007 Korean National Growth Chart and that in 1998 except middle school boys group. Conclusion: We found that there is a decrease in prevalence of Obesity by BMI based on 2007 Korean National Growth Chart. It is necessary to evaluate correlation between criteria for obesity and obesity related comorbid conditions for finding proper BMI or relative weight cut off value to prevent obesity and obesity related complications effectively.

• Safety and Health at Work
• /
• 제10권1호
• /
• pp.114-121
• /
• 2019

Background: The photolithography process in the semiconductor industry uses various chemicals with little information on their constitution. This study aimed to identify the chemical constituents of photoresist (PR) products and their by-products and to compare these constituents with material safety data sheets (MSDSs) and analytical results. Methods: A total of 51 PRs with 48 MSDSs were collected. Analysis consisted of two parts: First, the constituents of the chemical products were identified and analyzed using MSDS data; second, for verification of the by-products of PR, volatile organic compounds were analyzed. The chemical constituents were categorized according to hazards. Results: Forty-five of 48 products contained trade secrets in amounts ranging from 1 to 65%. A total of 238 ingredients with multiple counting (35 ingredients without multiple counting) were identified in the MSDS data, and 48.7% of ingredients were labeled as trade secrets under the Korea Occupational Safety and Health Act. The concordance rate between the MSDS data and the analytical result was 41.7%. The by-product analysis identified 129 chemicals classified according to Chemical Abstracts Service No., with 17 chemicals that are carcinogenic, mutagenic, and reprotoxic substances. Formaldehyde was found to be released from 12 of 21 products that use novolak resin. Conclusion: We confirmed that several PRs contain carcinogens, and some were not specified in the toxicological information in the MSDS. Hazardous chemicals, including benzene and formaldehyde, are released from PRs products as by-products. Therefore, it is necessary to establish a systematic management system for chemical compounds and the working environment.

• 한국정보통신학회논문지
• /
• 제23권4호
• /
• pp.357-364
• /
• 2019

전현직 직원에 의한 산업정보 유출 비율이 80%에 이르나 산업정보유출 사고에 대한 뉴스기사나 정보유출 행위의 원인에 대한 연구들에서는 그 원인들을 처우나 인사 불만 등으로 간략하게 설명하고 있다. 본 연구에서는 전현직 직원들이 익명 기업리뷰 웹사이트에 남긴 기업에 대한 평가 텍스트를 분석하여 기업에 대한 불만 내용들을 더욱 구체적으로 확인하였다. 이 중 어떠한 불만사항이 퇴직이나 퇴사, 나아가 산업인력유출의 결과로 이어질 수 있는지 파악하기 위해 불만 분야에 대한 의미사전목록을 제시하고 부분문법그래프(LGG)를 구축하였다. 또한 텍스트 분석 결과에서 나타난 전현직 직원들의 불만사항과 기존 연구들에서 설문을 통해 정리한 인력유출 원인을 서로 비교하였다. 추가적으로 분석된 불만을 바탕으로 기업불만 해소를 통한 인력유출 방지 방안을 간략 제시하였다. 기존 설문 위주의 산업 인력 유출에 대한 분석에 더하여, 웹 크롤링을 통한 자유롭고 솔직한 불만 분석을 제공하는 데 의의가 있다.

• 한국동물위생학회지
• /
• 제45권1호
• /
• pp.19-30
• /
• 2022

In this study, a simple loop-mediated isothermal amplification (LAMP) combined with visual detection method (vLAMP) assay was developed for the rapid and specific detection of African swine fever virus (ASFV), overcoming the shortcomings of previously described LAMP assays that require additional detection steps or pose a cross-contamination risk. The assay results can be directly detected by the naked eye using hydroxynaphthol blue after incubation for 40 min at 62℃. The assay specifically amplified ASFV DNA and no other viral nucleic acids. The limit of detection of the assay was <50 DNA copies/reaction, which was ten times more sensitive than conventional polymerase chain reaction (cPCR) and comparable to real-time PCR (qPCR). For clinical evaluation, the ASFV detection rate of vLAMP was higher than cPCR and comparable to OIE-recommended qPCR, showing 100% concordance, with a κ value (95% confidence interval) of 1 (1.00~1.00). Considering the advantages of high sensitivity and specificity, no possibility for cross-contamination, and being able to be used as low-cost equipment, the developed vLAMP assay will be a valuable tool for detecting ASFV from clinical samples, even in resource-limited laboratories.

• Journal of Trauma and Injury
• /
• 제36권4호
• /
• pp.337-342
• /
• 2023

Purpose: This study aimed to compare the resting energy expenditure (REE) measured using indirect calorimetry with that estimated using predictive equations in severe trauma patients to determine the appropriate caloric requirements. Methods: Patients admitted to the surgical intensive care unit between January 2020 and March 2023 were included in this study. Indirect calorimetry was used to measure the patients' REE values. These values were subsequently compared with those estimated using predictive equations: the weight-based equation (rule of thumb, 25 kcal/kg/day), Harris-Benedict, Ireton-Jones, and the Penn State 2003 equations. Results: A total of 27 severe trauma patients were included in this study, and 47 indirect calorimetric measurements were conducted. The weight-based equation (mean difference [MD], -28.96±303.58 kcal) and the Penn State 2003 equation (MD, - 3.56±270.39 kcal) showed the closest results to REE measured by indirect calorimetry. However, the REE values estimated using the Harris-Benedict equation (MD, 156.64±276.54 kcal) and Ireton-Jones equation (MD, 250.87±332.54 kcal) displayed significant differences from those measured using indirect calorimetry. The concordance rate, which the predictive REE differs from the measured REE value within 10%, was up to 36.2%. Conclusions: The REE values estimated using predictive equations exhibited substantial differences from those measured via indirect calorimetry. Therefore, it is necessary to measure the REE value through indirect calorimetry in severe trauma patients.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제17권1호
• /
• pp.27-31
• /
• 2006

연구목적 : Streptococcus 감염에 취약한 생물학적 지표라고 알려진 D8/17 항체가 PANDAS로 의심되는 뚜렛장애 환자에서 높은지를 알아보고, 뚜렛장애군 중 D8/17 양성반응 여부에 따라 임상경과에 차이가 있는지를 알아보고자 본 연구를 시행하였다. 방 법 : PANDAS가 의심되는 뚜렛장애 소아환자 9명과 비교 대상으로 틱증상이 없이 일관되게 지속적으로 주의력결핍 과잉 행동장애를 보이는 2명의 소아를 택하여 B 임파구 D8/17 항원 양성반응 비율과 혈청 ASO 농도를 비교분석하였다. 결 과 : PANDAS가 의심되는 9명의 뚜렛장애 소아의 경우 평균 77.9%($50.9{\sim}100%$) D8/17 B임파구 양성 비율을 보여 비교대상인 2명의 ADHD(24.8%, 53.7%) 보다 의미 있게 높았다. 뚜렛장애 중 90% 이상의 높은 양성비율을 보이는 경우가 4예 (44..4%)였다. 특히 모녀 뚜렛장애인 경우 각각 98.4%, 99.0%라는 높은 수치를 보였다. 뚜렛장애의 심한 정도와 D8/17 양성 임파구 비율간에 의미있는 상관관계는 없었다. ASO titer와D8/17양성 임파구 비율간에 통계적으로 의미 있는 상관관계는 없었지만 뚜렛장애 66.7%에서 100IU/ml 이상을 보였다. 결 론 : 상기결과를 종합하여 볼 때 일부 뚜렛장애 환자의 경우 streptocooccus 감염과 연관된 PANDAS일 가능성이 충분히 있다고 판단되었다.

• Journal of Preventive Medicine and Public Health
• /
• 제40권4호
• /
• pp.285-290
• /
• 2007

Objectives : Cases of human brucellosis in Korea have recently increased due to the increasing incidence of bovine brucellosis. The authors conducted this study to elucidate the status of brucellosis through seroepidemiologic study. Methods : We selected our study population from a high risk group. We conducted a questionnaire survey and obtained blood samples to determine the seroprevalence of brucellosis antibodies for 10 days in February, 2005. The titers of brucellosis were measured by the combination of standard tube agglutination test (STA) and enzyme-linked immunosorbent assay (ELISA) test. Results : Our study subjects comprised 1,075 cases: 971 livestock workers, 51 veterinarians, and 53 artificial inseminators. In the STA test, 27 cases (2.5%) had titers of greater than or equal to 1:20. Of 1,068 cases (7 cases were excluded due to previous brucellosis), 7 cases of brucellosis were diagnosed with titers of 1:160, giving a seroprevalence of brucellosis of 0.66%. The seroprevalence in the male group was 0.95%, and that of livestock workers, veterinarians, and artificial inseminators was 0.52%, 4.17%, and 0.00%, respectively. The Spearman's correlation coefficient between the positive rate of bovine brucellosis per capita and household and human brucellosis was 0.806 and 0.744, respectively. The concordance rate between the Korea National Institute of Health and the Gyeongsangbuk-do Institute of Health and Environment by the STA and ELISA tests was 94.7% and 100.0%, respectively. Conclusions : The study results indicated in higher seroprevalence rate among veterinarians than among livestock workers and artificial inseminators. Because veterinarians may be exposed to this high risk, effective working guidelines for veterinarians to guard against brucellosis must be developed. Moreover, more extensive epidemiologic research for laboratory workers and meat handlers is needed.