• 제목/요약/키워드: Concentration gradient

검색결과 579건 처리시간 0.034초

포도당운반체의 분자생물학 (Molecular Biology of Glucose Transporter Families)

  • 안용호
    • 생명과학회지
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    • 제4권4호
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    • pp.170-175
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    • 1994
  • The glucose transport across the mammalian plasma membranes is carried out by members of two distinct gene families, $Na^+$/glucose to transporter (SGLT) and glucose transporters (GLUTs). The energy requiring SGLT utilizes the sodium gradient to transport glucose and galactose against the concentration gradient. The energy independent transport (Facilitative transport) of glucose down the concentration gradient is mediated by the members of GLUTs. The facilitated transport of glucose is saturable, sterospecific and bidirectional across the membrane. To date, 6 kinds of isoforms of facilitative glucose transporters are found. These proteins are expressed in a tissue and cell specific manner, and shows distinct properties that reflect their specific functional roles.

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Characteristics of Propagating Tribrachial Flames in Counterflow

  • Ko, Young-Sung;Chung, Tae-Man;Chung, Suk-Ho
    • Journal of Mechanical Science and Technology
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    • 제16권12호
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    • pp.1710-1718
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    • 2002
  • The effect of fuel concentration gradient on the propagation characteristics of tribrachial (or triple) flames has been investigated experimentally in both two-dimensional and axisymmetric counterflows. The gradient at the stoichiometric location was controlled by the equivalence ratios at the two nozzles; one of which is maintained rich, while the other lean. Results show that the displacement speed of tribrachial flames in the two-dimensional counterflow decreases with fuel concentration gradient and has much larger speed than the maximum speed predicted previously in two-dimensional mixing layers. From an analogy with premixed flame propagation, this excessively large displacement speed can be attributed to the flame propagation with respect to burnt gas. Corresponding maximum speed in the limit of small mixture fraction gradient was estimated and the curvefit of the experimental data substantiates this limiting speed. As mixture fraction gradient approaches zero, a transition occurs, such that the propagation speed of tribrachial flame approaches stoichiometric laminar burning velocity with respect to burnt gas. Similar results have been obtained for tribrachial flames propagating in axisymmetric counterflow.

대향류 유동장에서 삼지 화염 전파 특성에 관한 연구 (Characteristics of Propagating Tribrachial Flames in Counterflow)

  • 정태만;고영성;정석호
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2000년도 춘계학술대회논문집B
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    • pp.422-427
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    • 2000
  • Propagation characteristics of tribrachial flames have been investigated experimentally in both two-dimensional and axisymmetric counterflows. Mixture fraction gradient at stoichiometric location is controlled by varying equivalence ratios at the two nozzles, one of which maintains rich while the other lean premixture. Tribrachial flames propagating through these mixtures are investigated. The propagation speed of tribrachial flames in two-dimensional counterflow decreases with fuel concentration gradient and has much higher speed than the maximum speed predicted previously in two-dimensional mixing layers. From an analogy with premixed flame propagation, this excessively large propagation speed can be attributed to the tribrachial flame propagating with respect to burnt gas. Corresponding maximum speed in the limit of small mixture fraction gradient is estimated and extrapolated experimental results substantiate this limiting speed. As mixture fraction gradient approaches zero, a transition in propagation characteristics occurs, such that the propagation speed of tribrachial flame approaches stoichiometric laminar burning velocity with respect to burnt gas. Similar behavior has been obtained for tribrachial flames propagating in axisymmetric counterflow.

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주화성에 의한 활동성 정자 분리용 마이크로 바이오칩에 관한 연구 (A Study About Microbiochip for Separation of Motile Sperm by Using Chemotaxis)

  • 고용준;맹준호;안유민;황승용
    • 대한기계학회논문집A
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    • 제32권12호
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    • pp.1115-1122
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    • 2008
  • This paper presents a new microchip which can separate motile sperm by chemotaxis. The microchip was developed to create longitudinal concentration gradient in the microchannel due to diffusion. Linearly good concentration gradient of chemoattractant was generated without any fluid control devices. In sperm separation experiment with the developed microchip, mouse sperm was used as sample and acetylcholine was selected as chemoattractant. Human tubal fluid (HTF), buffer solution, was introduced into the microchannel of the microchip and attractants diluted in ratio of 1, 1/2, 1/4, 1/8, 1/16, 1/32 and 1/64 including control (DI water) were dropped in each outlet by $2\;{\mu}l$ volume with micropippet. After 5min, $1\;{\mu}l$ sperm solution was dropped into inlet of the chip. After 10 min, when sperms reached to the outlet by chemotaxis, we counted sperms in each outlet by using microscopy. Consequently, we could separate progressive motile sperm with the new microchip. In the experiment, the most sperms were isolated at the outlet dropped with 1/16 diluted solution. The optimal concentration gradient to induce chemotaxis was about 0.625 mg/ml/mm.

Batch Column에서의 슬러지농도변화에 대한 연구 (Study on Sludge Concentration Change in Batch Column)

  • 박석균;강선홍;김동하
    • 상하수도학회지
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    • 제20권3호
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    • pp.443-450
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    • 2006
  • For understanding sludge concentration profile as a function of time, sludge was sampled at each sampling port. When sludge concentration was 3g/L, the vertical sludge concentration distribution was similar to that of 2g/L of sludge concentration. During the early stage of sludge settling, sludge concentration increased remarkably as the sludge interface height in batch column became lower. The higher sludge concentration became, the worse sludge setteability became. Also, the type of sludge settling was influenced with sludge concentration gradient in batch column. In the same concentration, the greater sludge concentration gradient was, the faster sludge interface settled down. And the changing sludge concentrations in a batch settling or a continuous settling were simulated by using the equation of sludge interface height change model.

대청호 Chl-a 예측을 위한 random forest와 gradient boosting 알고리즘 적용 연구 (A study on applying random forest and gradient boosting algorithm for Chl-a prediction of Daecheong lake)

  • 이상민;김일규
    • 상하수도학회지
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    • 제35권6호
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    • pp.507-516
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    • 2021
  • In this study, the machine learning which has been widely used in prediction algorithms recently was used. the research point was the CD(chudong) point which was a representative point of Daecheong Lake. Chlorophyll-a(Chl-a) concentration was used as a target variable for algae prediction. to predict the Chl-a concentration, a data set of water quality and quantity factors was consisted. we performed algorithms about random forest and gradient boosting with Python. to perform the algorithms, at first the correlation analysis between Chl-a and water quality and quantity data was studied. we extracted ten factors of high importance for water quality and quantity data. as a result of the algorithm performance index, the gradient boosting showed that RMSE was 2.72 mg/m3 and MSE was 7.40 mg/m3 and R2 was 0.66. as a result of the residual analysis, the analysis result of gradient boosting was excellent. as a result of the algorithm execution, the gradient boosting algorithm was excellent. the gradient boosting algorithm was also excellent with 2.44 mg/m3 of RMSE in the machine learning hyperparameter adjustment result.

복합대류가 이원용액의 응고과정에 미치는 영향에 관한 수치적 연구 (A Numerical Study on the Solidification of Binary Mixture with Double-diffusive Convection in the Liquid)

  • 유재석
    • 설비공학논문집
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    • 제5권2호
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    • pp.111-121
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    • 1993
  • Double-diffusive convection during solidification process of the binary mixture was studied numerically. Enthalpy method and finite element method were implemented in the analysis. Calculation carried out for $R{\alpha}_T=10^3-10^4$ and $R{\alpha}_T=0-10^5$. The results show that the variation of thermal Rayleigh number changes the fields of velocity, temperature and concentration, but the variation of solutal Rayleigh number gives little effects on those. In conclusion, concentration gradient can be negligible compared with temperature gradient in macroscopic point of view, although concentration gradient plays a role in forming dendrite.

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연료희석이단면확대채널에형성된삼지화염의전파속도에미치는영향에관한실험적연구 (An Experimental Study on the Effect of Fuel Dilution on the Propagation Velocity of Triple Flames in a Diverging Channel)

  • 서정일;신현동;김남일
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2007년도 제34회 KOSCO SYMPOSIUM 논문집
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    • pp.13-18
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    • 2007
  • When triple flames propagated in a diverging channel, the effects of fuel dilution on the lift-off characteristics of triple flames were investigated. A multi-slot burner was used to stabilize the lift-off flame especially at weak fuel concentration gradients. It was reported that there is a maximum propagation velocity at a critical concentration gradient in an open jet regardless of fuel dilution. The enhancement of a diffusion flame affected to increase the propagation velocity around critical concentration gradients. However, the influence of a confined channel on the structure of triple flames according to fuel dilution needs to be investigated compared with an open jet case. This study aimed to examine the effect of a confined channel on the structure and the propagation velocity of the triple flames according to fuel dilution. Lift-off height and propagation velocity of triple flames were investigated by employing three kinds of fuel compositions diluted by nitrogen (0%, 25%, 50% $N_2$), Fuel dilution reduced the propagation velocity of triple flame in a confined channel mainly due to the decrease of flame temperature in premixed branch. Despite the difference in fuel dilution, the propagation velocity has a maximum value at a specific fuel concentration gradient even though the critical concentration gradient increases with fuel dilution. And the critical concentration gradient in a confined channel is larger than that in an open jet due to enhancement of convective diffusion.

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X-정자와 Y-정자의 분류에 관한 연구 IV. Sephadex Gel여과법과 Percoll중층원심분류법의 병용에 의한 우 정자의 분류 (Separation of X-and Y-Bearing Spermatozoa IV. Separtion of bull spermatozoa by the combination of density Gradient Centrifugation and Sephadex Gel filtration)

  • 이주영;정길생;김종배
    • 한국가축번식학회지
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    • 제12권3호
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    • pp.141-147
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    • 1988
  • These experiments were carried out to develop new techniques for in vitro separation of x-and Y-bearing spermatozoa. The results obtained in these experiments were summarized as follows: 1. Following centrifugation of discontinuous percoll density gradient, populatin of spermatozoa increased progressively from low to high density. The highest concentration of spermatozoa was observed at the 4th fraction which included 36.6% of spermatozoa. 2. As increasing percoll concentration, the higher motility index was obtained and the highest motility index(74.2) was obtained at the 5th fraction. 3. The percentage of B-body bearing spermatozoa following percoll density gradient centrifugation was decreased from 39.7% to 25.6%. 4. The sperm population following chromatography by sephadex gel and percoll density gradient centrifugation was decreased in 1st, 5th and 6th fractions but the reverse was turn for 2nd, 3rd and 7th fractions, and the highest sperm concentration was observed at the 7th fraction which included 37.4% of spermatozoa. 5. Motility index of spermatozoa was increased from 77.6 to 79.4 after the sephadex gel filtration, however it was decreased at all fractions after percoll density gradient centrifugation. The lowest motility index(33.2) was obtained from the 7th fraction. 6. The rate of B-body bearing spermatozoa was shown the trend to decrease by the sephadex gel filtration and the trend was accelerated by the percoll density gradient centrifugation. The lowest percentage of B-body bearing spermatozoa, 12.0% was obtained from the 5th fraction.

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Real-time Monitoring of Colloidal Nanoparticles using Light Sheet Dark-field Microscopy Combined with Microfluidic Concentration Gradient Generator (μFCGG-LSDFM)

  • Choe, Hyeokmin;Nho, Hyun Woo;Park, Jonghoon;Kim, Jin Bae;Yoon, Tae Hyun
    • Bulletin of the Korean Chemical Society
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    • 제35권2호
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    • pp.365-370
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    • 2014
  • For real-time monitoring of colloidal nanoparticles (NPs) in aqueous media, a light sheet type dark-field microscopy system combined with a microfluidic concentration gradient generator (${\mu}FCGG$-LSDFM) was developed. Various concentrations of colloidal Au NPs were simultaneously generated with the iFCGG and characterized with the LSDFM setup. The number concentrations and hydrodynamic size distributions were measured via particle counting and tracking analysis (PCA and PTA, respectively) approaches. For the 30 nm Au NPs used in this study, the lower detection limit of the LSDFM setup was 3.6 ng/mL, which is about 400 times better than that of optical density measurements under the same ${\mu}FCGG$ system. Additionally, the hydrodynamic diameter distribution of Au NPs was estimated as $39.7{\pm}12.2nm$ with the PTA approach, which agrees well with DLS measurement as well as the manufacturer's specification. We propose this ${\mu}FCGG$-LSDFM setup with features of automatic generation of NP concentration gradient and real-time monitoring of their physicochemical characteristics (e.g., number concentration, and hydrodynamic size distribution) as an important component of future high-throughput screening or high-content analysis platforms of nanotoxicity.