• Journal of Applied Biological Chemistry
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• v.55 no.4
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• pp.217-220
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• 2012

The fruits of Acanthopanax sessiliflorus Seeman (Araliaceae) were extracted with 70% aqueous ethanol at room temperature. The concentrated extract was partitioned with ethyl acetate (EtOAc), n-butyl alcohol, and $H_2O$, successively. From the EtOAc fraction, two compounds were isolated through the repeated silica gel, octadecyl silica gel, and Sephadex LH-20 column chromatographies. According to the results of physicochemical and spectroscopic data including NMR, mass spectrometry, and infrared spectroscopy, the chemical structures of the compounds were determined as 3,5-dihydroxycinnamic acid (1) and protocatechuic acid (2). Compound 1 was isolated from the fruits of A. sessiliflirus Seeman for the first time. And the compounds were evaluated for the radical scavenging the antioxidant capacity using 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)diammonium salt, 1,1-diphenyl-2-picrylhydrazy, and oxygen radical absorbance capacity assay.

• Korean journal of communication and information
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• v.20
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• pp.141-176
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• 2003

This paper examined how Korean courts conceptualized and applied public interest defense of Penal Code to the libel cases raised by socially influential persons. For this, this paper analyzed a total of 58 libel cases in which 'public interest' was mentioned by Korean courts between 1981 and 2000. It was found that whereas truth or believed-to-be-true defense is emphasized In libel cases by politicians or public officials, public interest defense was emphasized in the cases by private figures. It was also found that Korean courts tended to think of matters related with 1) national security and social order, 2) prevention of asocial crime, 3) enlightening of public, and 4) protection of consumers' interest as public interest. Conclusively, 'public interest' is not simply applied as an independent legal defense, because Korean courts insistently concentrated on the truth of a story and did not even specifically define what is public interest. Constitution Court recently maintained that the slope of legal defense should be broadened when a story is about public matters. However, Korean courts will not be likely to accept public interest defense as an independent one for the time being.

• Ocean and Polar Research
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• v.39 no.2
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• pp.85-106
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• 2017

The Lago Sofia conglomerate in southern Chile is a deep-marine gravelly deposit, which is hundreds of meters thick and kilometers wide and extends laterally for more than 100 km, filling the foredeep trough of the Cretaceous Magallanes Basin. For understanding the depositional processes and environments of this gigantic deep-sea conglomerate, detailed analyses on sedimentary facies, architecture and paleoflow patterns were carried out, highlighting the differences between the northern (Lago Pehoe and Lago Goic areas) and southern (Lago Sofia area) parts of the study area. The conglomerate bodies in the northern part occur as relatively thin (< 100 m thick), multiple units intervened by thick mudstone-dominated sequences. They show paleoflows toward ENE and S to SW, displaying a converging drainage pattern. In the southern part, the conglomerate bodies are vertically interconnected and form a thick (> 400 m thick) conglomerate sequence with rare intervening fine-grained deposits. Paleoflows are toward SW. The north-to-south variations are also distinct in sedimentary facies. The conglomerate bodies in the southern part are mainly composed of clast-supported conglomerate with sandy matrix, which is interpreted to be deposited from highly concentrated bedload layers under turbidity currents. Those in the northern part are dominated by matrix- to clast-supported conglomerate with muddy matrix, which is interpreted as the products of composite mass flows comprising a turbidity current, a gravelly hyperconcentrated flow and a mud-rich debris flow. All these characteristics suggest that the Lago Sofia conglomerate was formed in centripetally converging submarine channels, not in centrifugally diverging channels of submarine fans. The tributaries in the north were dominated by mass flows, probably affected by channel-bank failures or basin-marginal slope instability processes. In contrast, the trunk channel in the south was mostly filled by tractive processes, which resulted in the vertical and lateral accretion of gravel bars, deposition of gravel dunes and filling of scours and channels, similar to deposits of terrestrial gravel-bed rivers. The trunk channel developed along the axis of foredeep trough and its confinement within the trough is probably responsible for the thick, interconnected channel fills. The large-scale architecture of the trunk-channel fills shows an eastward offset stacking pattern, suggesting that the channel migrated eastwards most likely due to the uplift of the Andean Cordillera.

• Korean journal of communication and information
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• v.46
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• pp.485-510
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• 2009

Since the inception of Internet Protocol TV's real-time service on January, 2009, technological challenges and lack of content diversity of IPTV have been cited as problem areas. While past researches focused on IPTV's technological, industrial and policy facets, this research surveyed the viewers' viewing and usage patterns, and the level of service satisfaction among actual audiences of MegaTV, SKBroadband, and LGTV since January. The results show that subscription fee and content types were the two dominant determinants in audience's choice of a particular IPTV company. The high users of IPTV were on average aged between 30-39, and women tended to be heavier users than men. The surveyed audience also regarded IPTV to be more similar to the Internet than any other medium such as Cable TV and Satellite TV. IPTV audience cited 'lifestyle service' and 'additional service' offerings to be highly relevant to their usage and satisfaction; interactive service and educational service also showed high correlation to usage and satisfaction. The most watched contents on IPTV were domestic TV series, followed by foreign movies and variety shows. 'Fees for additional features,' 'lack of real-time terrestrial TV service', and 'lack of content variety' were the major areas of concern for IPTV viewers. They answered that the monthly fee was the most important factor in the selection of IPTV. Use of pay-per-view contents and add-on interactive service fees were also seen as problematic. With regards to future usage, the IPTV audience revealed that they were very sensitive and reluctant to pay for additional services. While existing researches concentrated on IPTV's technological problems and lack of content diversity, this study illuminated the more pragmatical side of the viewers, namely, the importance of price in audience's selection of an IPTV service provider. From these results, it is recommended that, before doing anything else, the service providers try to meet the audience's expected price points in order to garner the full potential of IPTV and the attendant mass audience.

• Journal of the Society of Naval Architects of Korea
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• v.32 no.3
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• pp.116-125
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• 1995

In ship and of offshore structures, there exist many local panels of various shapes having many kinds of attachments reducible to damped spring-mass systems. For the vibration analysis of panels, analytical methods such as Rayleight-Ritz method or the assumed mode method can be efficiently applied. There have been many studies on the vibration analysis of rectangular panels using the analytical methods but relatively few for arbitrary shape panels. An efficient formulation based on the assumed mode method is presented for the vibration analysis of an arbitrary quadrangular plate having concentrated masses, supporting springs such as pillars and spring-mass systems. In the formulation, the natural coordinate system is used for the efficient treatment of an arbitrary quadrangular shape. Through some numerical calculations, accuracy and efficiency of the presented method are shown.

• Journal of fish pathology
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• v.26 no.3
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• pp.193-206
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• 2013

The ark shell, Scapharca broughtonii is a marine bivalve mollusks belonging to the family Arcidae and important seafood for Korean and Japanese, and southern coast is brisk bays for the ark shell aquaculture. However, productivity of ark shell from these regions were rapidly reduced during the last decade due to mass mortality. The reason of this great damage has not yet been identified. To overcome this economic loss, diverse investigations were focused on environmental factors that affects in the physiology of S. broughtonii, but microbiological researches were performed insufficiently. Hemoglobin is one of the major blood component of ark shell and is damaged by some species of bacterial toxins. We concentrated on this red pigment because hemolysis could be the cause of ark shell mortality. In this study, we analyzed microbial diversity of underwater sediments in coastal regions and also existences in the body of S. broughtonii. We investigate about 4,200 isolates collected from June to September for microbial diversity of sediments and ark shell. We screened all of culturable microorganisms, and identified 25 genera 118 species, 24 genera 89 species, 30 genera 109 species and 39 genera 141 species, and selected 140 unique colonies for identification and challenge assay.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.2
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• pp.28-48
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• 2019

This research is aimed at identifying the perception associated with urban regeneration and predicting policy implications of future directions by analyzing the trend of urban regeneration depicted in the mass media by utilizing SNA (Semantic-Network Analysis) techniques. As the number of articles has increased, it is noted through analysis that the interrelationships between social phenomena and issues have combined to form the meaning of urban regeneration. Overall, 'urban' and 'regeneration' keywords also appeared at different periods, with 'urban' closely related to 'regeneration' starting in 1970 when urbanization was becoming more prevalent. It was analyzed that the frequency of 'urban' appeared more frequently in the early 1990s, while the frequency of 'rural' decreased sharply. Until the 1990s, the slums and the recession that appeared as side effects of urban problem-solving policies were mostly concentrated in cities. Policy discussions were conducted with the goal of improving the physical environment of cities rather than concentrating on the surrounding rural areas. The distributions of the keywords 'development' and 'regeneration' have increased quantitatively since the 1970s, and urban polarization has exploded due to the development of the external growth of cities, mirroring the trend of accelerated environmental threats. In particular, the keywords for 'regeneration' emerged mainly related to environmental problems, which led to the need for urban regeneration, and environmentally and ecologically friendly development. The emergence of "urban," "regeneration" and "environment" as keywords having to do with urban regeneration grew in the 1990s. This suggests that urban regeneration is now linked to "environment", as that has become a social issue.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.35 no.2
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• pp.93-100
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• 2022

The collision behaviors of the tripod and jacket structures, which are considered as support structures for offshore wind towers at the Southwest sea of Korea, were compared by nonlinear dynamic analysis. These structures, designed for the 3 MW capacity of the wind towers, were modeled using shell elements with nonlinear behaviors, and the tower structure including the nacelle, was modeled by beam and mass elements with elastic materials. The mass of the tripod structure was approximately 1.66 times that of the jacket structure. A barge and commercial ship were modeled as the collision vessel. To consider the tidal conditions in the region, the collision levels were varied from -3.5 m to 3.5 m of the mean sea level. In addition, the collision behaviors were evaluated as increasing the minimum collision energy at the collision speed (=2.6 m/s) of each vessel by four times, respectively. Accordingly, the plastic energy dissipation ratios of the vessel were increased as the stiffness of collision region. The deformations in the wind tower occurred from vibration to collapse of conditions. The tripod structure demonstrated more collision resistance than the jacket structure. This is considered to be due to the concentrated centralized rigidity and amount of steel utilized.

• Journal of Life Science
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• v.22 no.11
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• pp.1456-1462
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• 2012

Sorafenib is a multikinase inhibitor and an oral anticancer drug approved for the treatment of patients with advanced renal cell carcinoma and those with unresectable hepatocellular carcinoma. The purpose of this study was to develop an efficient method of the determination of sorafenib in human plasma using tandem mass spectrometry coupled with liquid chromatography (LC/MS/MS) and validate the method by the guidelines of the Korean Food and Drug Administration (KFDA). Plasma samples ($100{\mu}l$) were added with chlorantraniliprole as an internal standard and then mixed with the 0.1% formic acid-containing extraction solution composed of isopropyl alcohol and ethyl acetate (1:4, v/v). After centrifugation, the supernatant was concentrated at $45^{\circ}C$ under negative pressure and centrifugal force. The residue was reconstituted with a mobile phase and injected into the HPLC instrument using a reverse phase Waters XTerra$^{TM}$ C18 column (particle size $3.5{\mu}m$). Liquid chromatography was carried out within the run time of 5 min using a mobile phase composed of buffer (0.1% formic acid and 10 mM ammonium formate), methanol, and acetonitrile (1:6:3, v/v/v). The analytes were monitored by tandem mass spectrometry in the multiple reaction monitoring method programmed to detect sorafenib at 'm/z 465.2 ${\rightarrow}$ 252.5' and chlorantraniliprole at 'm/z 484.4 ${\rightarrow}$ 286.2' with positive electrospray ionization mode ($ES^+$). The result showed the proper linearity ($r^2$ > 0.99) over the range of 2,000-5,000 ng/ml with good accuracy (90.7-103.9%) and precision (less than 10%). The newly developed method using LC/MS/MS was validated by the guideline of KFDA and identified as more sensitive compared to the previous methods.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.2 no.2
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• pp.151-159
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• 1997

Benthic respiration and chemical fluxes were measured at the sediment-water interface underlying the marine fish cages floating on the open coastal waters off Tong-Young, the South Coast of Korea. The effects of cage farming on coastal benthic environment and on mass balance of organic carbon in the benthic boundary layer under the marine fish cages are addressed. In a growing season of caged fishes of June, 1995, benthic chambers and sediment traps were deployed on the sediment-water interfaces of the two sites chosen for this study: 1) Cage Site, directly underlying the fish cages of the farm at 18 m water depth, and 2) Control Site, about 100 m away from the farm at 32 m water depth. Benthic respiration rates and chemical fluxes were calculated from the evolution of dissolved oxygen and chemicals in the chamber water, and mass balance of organic carbon in the benthic boundary layer was constructed based on the vertical flux of particulate organic matter (POM) and chemical fluxes out of the sediment. High organic dumping (6400 mg C $m^{-2}d^{-1}$) and high benthic respiration (230 mmol $O_2\;m^{-2}d^{-1}$) were observed at the Cage Site. Equivalent to 40% of vertical flux of organic carbon into the Cage Site seemed to be decomposed concurrently and released back to overlying waters (2400 mg C $m^{-2}d^{-1}$). Consequently, up to 4000 mg C $m^{-2}d^{-1}$ of organic carbon could be buried into the farm sediment (equivalent to 60% of organic carbon flux into the Cage Site). At the Control Site, relatively less input of organic carbon (4000 mg C $m^{-2}d^{-1}$) and low benthic respiration rate (75 mmol $O_2\;m^{-2}d^{-1}$) were observed despite short distance away from the cages. The influence of cage farming on benthic chemical fluxes might be restricted and concentrated in the sea bottom just below the fish cages in spite of massive organic dumping and high current regime around the fish cage farm.