• 제목/요약/키워드: Computer modeling

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The estimation of Draize score by in vitro cytotoxicity using continuous cell lines (In Vitro cytotoxicity에 의한 Draize score 측정 체계 수립)

  • 정민석;최종완
    • Proceedings of the SCSK Conference
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    • 1996.07a
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    • pp.33-51
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    • 1996
  • 화장품의 변질요인은 크게 물리적 또는 화학적 변화에 의한 요인과 미생물오염으로 인한 각종 문제점으로 대별될 수 있다. 이 중에서 미생물 오염문제는 제품의 상품가치에 미치는 영향 뿐만 아니라 지속적인 사용에 의한 피부의 위생적 측면때문에 그 중요성에 대한 인식이 높아지고 있다. 따라서, 제품개발시는 화장품 처방중의 영양성분의 배합, pH, 유화형태, 방부제의 혼합, 분배계수 및 그 안정성을 고려하여야 함은 물론이고 처방중의 모든 원료의 각각에 대한 항균능 및 피부자극여부를 사전에 미리 조사하여 각 제품별로 적당한 방부체계를 선택하는 것은 매우 중요한일이다. 독성실험방법에 있어서 in vivo 실험에 대체할 수 있는 새로운 in vitro 실험방법 수립 즉, 동물실험을 하지 않고 in vitro 실험결과로부터 in vivo 결과를 예측할 수 있도록 새로운 in vitro 실험체계의 가능성을 실험하였다. 4종의 cell line중 transformed mouse fibroblast L929가 본 실험에서 사용하기에 배양상의 용이성과 안정성, 재현성의 관점에서 가장 알맞은 cell line이었다. transformed mouse fibroblast L929를 사용한 NR$_{50}$ assay와 Draize score간의 regression coefficient ${\gamma}$값은 0.91이었다. 혈청은 시험물질의 세포에 대한 민감성에 영향을 주었다. 따라서, modified serum-free method를 이용함으로써 regression coefficient가 증가된 즉, 상관성 및 재현성이 높은 결과를 얻을 수 있었다. 이러한 기술은 독성실험에 실험동물을 사용하지 않고 in vivo test에 대체 할 수 있고, 또한 화학물질에 대한 prescreening으로 이용할 수 있을 것으로 판단된다.원과 섭식장소, 수중생물의 경우는 특히 수온, 수량 영양원등이다.(중략). 본 연구의 접근방법으로는 ASRS의 개념적인 Reference Model을 수립하고 이 Reference Model에 대한 Formal Model로 DEVS(Discrete Event System Specification)을 이용하여 시스템을 Modeling하였다. 이의 Computer Simulation을 위하여 DEVS형식론 환경에서의 Simulation Language인 DEVSim ++ⓒ를 이용하여 시스템을 구현하였다.. 실형 결과로는 먼저 선형 상미분방정식의 예로 mass-damper-spring system, 비선형 상미분방정식의 예로는 van der Pol 방정식, 연립 상미분방정식의 예로는 mixing tank problem 등을 보였으며, 그의 공학에서 일어나는 여러 가지 문제들도 다루었다.화물에 대한 방어력이 증가되어 나타난 결과로 여겨지며, 또한 혈청중의 ALT, ALP 및 LDH활성을 유의성있게 감소시키므로서 감잎 phenolic compounds가 에탄올에 의한 간세포 손상에 대한 해독 및 보호작용이 있는 것으로 사료된다.반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경우는 홍삼으로 가공되면서 발생하는 경우가 있고, 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$ elements)로 가정한다. 즉, [+wh] 의미의 겹의문사는 동일한 구성요 소를 지닌 병렬적 합성어([$[W1]_{XO-}$ $[W1]_{XO}$ ]

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U-Net Cloud Detection for the SPARCS Cloud Dataset from Landsat 8 Images (Landsat 8 기반 SPARCS 데이터셋을 이용한 U-Net 구름탐지)

  • Kang, Jonggu;Kim, Geunah;Jeong, Yemin;Kim, Seoyeon;Youn, Youjeong;Cho, Soobin;Lee, Yangwon
    • Korean Journal of Remote Sensing
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    • v.37 no.5_1
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    • pp.1149-1161
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    • 2021
  • With a trend of the utilization of computer vision for satellite images, cloud detection using deep learning also attracts attention recently. In this study, we conducted a U-Net cloud detection modeling using SPARCS (Spatial Procedures for Automated Removal of Cloud and Shadow) Cloud Dataset with the image data augmentation and carried out 10-fold cross-validation for an objective assessment of the model. Asthe result of the blind test for 1800 datasets with 512 by 512 pixels, relatively high performance with the accuracy of 0.821, the precision of 0.847, the recall of 0.821, the F1-score of 0.831, and the IoU (Intersection over Union) of 0.723. Although 14.5% of actual cloud shadows were misclassified as land, and 19.7% of actual clouds were misidentified as land, this can be overcome by increasing the quality and quantity of label datasets. Moreover, a state-of-the-art DeepLab V3+ model and the NAS (Neural Architecture Search) optimization technique can help the cloud detection for CAS500 (Compact Advanced Satellite 500) in South Korea.

Analysis of Abnormal Path Loss in Jeju Coastal Area Using Duct Map (덕트맵을 이용한 제주해안지역 이상 전파특성 분석)

  • Wang, Sungsik;Lim, Tae-Heung;Chong, Young Jun;Go, Minho;Park, Yong Bae;Choo, Hosung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.30 no.3
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    • pp.223-228
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    • 2019
  • This study analyzes the propagation of the path losses between Jeju-do and Jin-do transceivers located in the coastal areas of Korea using the Advanced Refractive Prediction System(AREPS) simulation software based on the actual coastal weather database. The simulated data is used to construct a duct map according to the altitude and thickness of the trap. The duct map is then divided into several regions depending on the altitude parameters of Tx and Rx, which can be used to effectively estimate the abnormal wave propagation characteristics due to duct occurrence in the Jeju-do coastal area. To validate the proposed duct map, two representative atmospheric index samples of the weather database in May 2018 are selected, and the simulated path losses using these atmospheric indices are compared with the measured data. The simulated path losses for abnormal conditions at the Rx point at Jeju-do are 167.7 dB and 192.3 dB, respectively, which are in good agreement with the measured data of 164.4 dB and 194.9 dB, respectively.

Development of KBIMS Architectural and Structural Element Library and IFC Property Name Conversion Methodology (KBIMS 건축 및 구조 부재 라이브러리 및 IFC 속성명 변환 방법 개발)

  • Kim, Seonwoo;Kim, Sunjung;Kim, Honghyun;Bae, Kiwoo
    • Journal of the Korea Institute of Building Construction
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    • v.20 no.6
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    • pp.505-514
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    • 2020
  • This research introduces the method of developing Korea BIM standard (KBIMS) architectural and structural element library and the methodology of converting KBIMS IFC property names with special characters. Diverse BIM tools are utilizing in project, however BIM library researches lack diversity on BIM tool selection. This research described the method to generate twelve categories and seven hundred and ninety-three elements library containing geometrical and numerical data in CATIA V6. KBIMS has its special property data naming systems which was the challenge inputting to ENOVIA IFC database. Three mapping methods for special naming characters had been developed and the ASCII code method was applied. In addition, the convertor prototype had been developed for searching and replacing the ASCII codes into the original KBIMS IFC property names. The methodology was verified by exporting 2,443 entities without data loss in the sample model conversion test. This research would provide a wider choice of BIM tool selection for applying KBIMS. Furthermore, the research would help on the reduction of data interoperability issues in projects. The developed library would be open to the public, however the continuous update and maintenance would be necessary.

Detection of Marine Oil Spills from PlanetScope Images Using DeepLabV3+ Model (DeepLabV3+ 모델을 이용한 PlanetScope 영상의 해상 유출유 탐지)

  • Kang, Jonggu;Youn, Youjeong;Kim, Geunah;Park, Ganghyun;Choi, Soyeon;Yang, Chan-Su;Yi, Jonghyuk;Lee, Yangwon
    • Korean Journal of Remote Sensing
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    • v.38 no.6_2
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    • pp.1623-1631
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    • 2022
  • Since oil spills can be a significant threat to the marine ecosystem, it is necessary to obtain information on the current contamination status quickly to minimize the damage. Satellite-based detection of marine oil spills has the advantage of spatiotemporal coverage because it can monitor a wide area compared to aircraft. Due to the recent development of computer vision and deep learning, marine oil spill detection can also be facilitated by deep learning. Unlike the existing studies based on Synthetic Aperture Radar (SAR) images, we conducted a deep learning modeling using PlanetScope optical satellite images. The blind test of the DeepLabV3+ model for oil spill detection showed the performance statistics with an accuracy of 0.885, a precision of 0.888, a recall of 0.886, an F1-score of 0.883, and a Mean Intersection over Union (mIOU) of 0.793.

Design and Implementation of Interface System for Swarm USVs Simulation Based on Hybrid Mission Planning (하이브리드형 임무계획을 고려한 군집 무인수상정 시뮬레이션 시스템의 연동 인터페이스 설계 및 구현)

  • Park, Hee-Mun;Joo, Hak-Jong;Seo, Kyung-Min;Choi, Young Kyu
    • Journal of the Korea Society for Simulation
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    • v.31 no.3
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    • pp.1-10
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    • 2022
  • Defense fields widely operate unmanned systems to lower vulnerability and enhance combat effectiveness. In the navy, swarm unmanned surface vehicles(USVs) form a cluster within communication range, share situational awareness information among the USVs, and cooperate with them to conduct military missions. This paper proposes an interface system, i.e., Interface Adapter System(IAS), to achieve inter-USV and intra-USV interoperability. We focus on the mission planning subsystem(MPS) for interoperability, which is the core subsystem of the USV to decide courses of action such as automatic path generation and weapon assignments. The central role of the proposed system is to exchange interface data between MPSs and other subsystems in real-time. To this end, we analyzed the operational requirements of the MPS and identified interface messages. Then we developed the IAS using the distributed real-time middleware. As experiments, we conducted several integration tests at swarm USVs simulation environment and measured delay time and loss ratio of interface messages. We expect that the proposed IAS successfully provides bridge roles between the mission planning system and other subsystems.

Model-based Design and Verification of High-lift Control System Using a Performance Analysis Model (성능해석 모델을 활용한 고양력 제어시스템의 모델기반 설계 및 검증)

  • Cho, Hyunjun;Kim, Taeju;Kim, Eunsoo;Kim, Sangbeom;Lee, Joonwon
    • Journal of Aerospace System Engineering
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    • v.16 no.2
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    • pp.49-62
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    • 2022
  • The purpose of this paper was to present a model analysis-based design process and verification results for the high-lift control system of aircraft. For this, we used Matlab/Simulink, one of the most widely-used physical modeling tools. The high-lift control system can be divided into three domains. (i.e., Electronic control domain, Hydraulic actuation domain, and Mechanical power transmission domain) Based on this division, we modeled each of the major domains and sub-components, and integrated them to complete the complicated system model. During the development process, each model block was tuned by referring to the results of pre-test and parts acceptance tests. As a result, the entire performance model and the developed system were completely verified, through unit components and system integrated performance tests. Finally, we summarize the process and results applied to the design process of high-lift control system and present future work.

Line Tracer Modeling for Educational Virtual Experiment (교육용 가상실험 라인 트레이서 모델링)

  • Ki, Jang-Geun;Kwon, Kee-Young
    • Journal of Software Assessment and Valuation
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    • v.17 no.2
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    • pp.109-116
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    • 2021
  • Traditionally, the engineering field has been dominated by face-to-face education focused on experimental practice, but demand for online learning has soared due to the rapid development of IT technology and Internet communication networks and recent changes in the social environment such as COVID-19. In order for efficient online education to be conducted in the engineering field, where the proportion of experimental practice is relatively high compared to other fields, virtual laboratory practice content that can replace actual experimental practice is very necessary. In this study, we developed a line tracer model and a virtual experimental software to simulate it for efficient online learning of microprocessor applications that are essential not only in the electric and electronic field but also in the overall engineering field where IT convergence takes place. In the developed line tracer model, the user can set various hardware parameter values in the desired form and write the software in assembly language or C language to test the operation on the computer. The developed line tracer virtual experimental software has been used in actual classes to verify its operation, and is expected to be an efficient virtual experimental practice tool in online non-face-to-face classes.

High-resolution Urban Flood Modeling using Cellular Automata-based WCA2D in the Oncheon-cheon Catchment in Busan, South Korea (셀룰러 오토마타 기반 WCA2D 모형을 이용한 부산 온천천 유역 고해상도 도시 침수 해석)

  • Choi, Hyeonjin;Lee, Songhee;Woo, Hyuna;Noh, Seong Jin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.43 no.5
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    • pp.587-599
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    • 2023
  • As climate change increasesthe frequency and risk of flooding in major cities around theworld, the importance ofsimulation technology that can quickly and accurately analyze high-resolution 2D flooding information in large-scale areasis emerging. The physically-based approaches based on the Shallow Water Equations (SWE) often requires huge computer resources hindering high-resolution flood prediction. This study investigated the theoretical background of Weighted Cellular Automata 2D (WCA2D), which simulates spatio-temporal changes offlooding using transition rules and weight-based system, and assessed feasibility to simulate pluvial flooding in the urbancatchment, theOncheon-cheon catchmentinBusan, SouthKorea.Inaddition,the computation performancewas compared by applying versions using OpenComputing Language (OpenCL) andOpenMulti-Processing (OpenMP) parallel computing techniques. Simulationresultsshowed that the maximuminundation depthmap by theWCA2Dmodel cansimilarly reproduce historical inundation maps. Also, it can precisely simulate spatio-temporal changes of flooding extent in the urban catchment with complex topographic characteristics. For computation efficiency, parallel computing schemes, theOpenCLandOpenMP, improved the computation by about 8~14 and 5~6 folds respectively, compared to the sequential computation.

Comparative analysis of the digital circuit designing ability of ChatGPT (ChatGPT을 활용한 디지털회로 설계 능력에 대한 비교 분석)

  • Kihun Nam
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.6
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    • pp.967-971
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    • 2023
  • Recently, a variety of AI-based platform services are available, and one of them is ChatGPT that processes a large quantity of data in the natural language and generates an answer after self-learning. ChatGPT can perform various tasks including software programming in the IT sector. Particularly, it may help generate a simple program and correct errors using C Language, which is a major programming language. Accordingly, it is expected that ChatGPT is capable of effectively using Verilog HDL, which is a hardware language created in C Language. Verilog HDL synthesis, however, is to generate imperative sentences in a logical circuit form and thus it needs to be verified whether the products are executed properly. In this paper, we aim to select small-scale logical circuits for ease of experimentation and to verify the results of circuits generated by ChatGPT and human-designed circuits. As to experimental environments, Xilinx ISE 14.7 was used for module modeling, and the xc3s1000 FPGA chip was used for module embodiment. Comparative analysis was performed on the use area and processing time of FPGA to compare the performance of ChatGPT products and Verilog HDL products.