• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.498-501
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• 2008

Knowledge of airflow characteristics in nasal cavities is essential to understand the physiological and pathological aspects of nasal breathing. Several studies have utilized physical models of the healthy nasal cavity to investigate the relationship between nasal anatomy and airflow. In our laboratory, there have been a series of experimental investigations on the nasal airflow in normal, abnormal, and deformed nasal cavity models cavity models by PIV under both constant and periodic flow conditions. In this time normal and several deformed nasal cavity models, which simulate surgical operation, Turbinectomy, are investigated numerically by the FVM general purpose code and PIV analysis. The comparisons of these results are appreciated. Dense CT data and careful treatment of model surface under the ENT doctor's advice provide more sophisticated cavity models. The Davis (LaVision Co.) code is used for PIV flow analysis. Average and RMS distributions have been obtained for inspirational and expirational nasal airflows in the normal and deformed nasal cavities.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.691-694
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• 2008

Spray characteristics of the APU simplex fuel nozzle are investigated. Four flight conditions such as sea level idle, sea level max power, 20,000 feet idle, 20,000 feet max power are used as spray experimental conditions. Spray visualization was performed by using ND-YAG laser. Droplet size and velocity were measured by using PDPA(Phase Doppler Particle Analyzer) system. From the test result, SMD is 100 ${\mu}$m�� and velocity is 10 m/s at 20,000 ft idle condition. In this condition, flame unstability could be occurred due to the higher drop diameter. Therefore it is necessary to decrease the droplet diameter in the high altitude condition.

• Journal of the Korean Statistical Society
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• 제31권4호
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• pp.519-532
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• 2002

K-means clustering is a well-known partitioning method of multivariate observations. Recently, the method is implemented broadly in data mining softwares due to its computational efficiency in handling large data sets. However, it does not yield a suitable visual display of multivariate observations that is important especially in exploratory stage of data analysis. The aim of this study is to develop a K-means clustering method that enables visual display of multivariate observations in a low-dimensional space, for which the projection pursuit method is adopted. We propose a computationally inexpensive and reliable algorithm and provide two numerical examples.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.135-140
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• 2004

Several studies have utilized physical models of the healthy nasal cavity to investigate the relationship between nasal anatomy and airflow. With our experiences of experimental investigations on nasal airflows in normal and abnormal nasal cavity models, we are going to deal with the topic that may contribute to the diagnosis and treatment of nasal diseases. In this paper, airflows in the normal and artificially deformed models, which simulate surgical treatment, are investigated experimentally by PIV. High-resolution CT data and careful surface rendering of computational model with the help of the ENT doctor provide more sophisticated nasal cavity models. The CBC PIV (Correlation Based Correction PIV) algorithm with window offset is used for PIV flow analysis. Average and RMS distributions in sagittal and coronal sections are obtained for inspiratory and expiratory nasal airflows. Comparisons in nasal airflows for both normal and deformed cases are also appreciated. In case of simulations of surgical operations, velocity and RMS distributions in coronal section changes locally, this may cause some difficulties in physiologic functions of noses and may hurt mucosal surface.

• 진공이야기
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• 제4권4호
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• pp.18-22
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• 2017

Transmission electron microscopy (TEM) is a versatile and powerful technique that enables direct visualization of biological samples of sizes ranging from whole cell to near-atomic resolution details of a protein molecule. Thanks to numerous technical breakthroughs and monumental discoveries, 3D electron microscopy (3DEM) has become an indispensable tool in the field of structural biology. In particular, development of cryo-electron microscopy(cryo-EM) and computational image processing played pivotal role for the determination of 3D structures of complex biological systems at sub-molecular resolution. Here, basis of TEM and 3DEM will be introduced, especially focusing on technical advancements and practical applications. Also, future prospective of constantly evolving 3DEM field will be discussed, with an anticipation of great biological discoveries that were once considered impossible.

• Genomics & Informatics
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• 제8권2호
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• pp.94-96
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• 2010

Integrating various pathway data collections to create new biological knowledge is a challenge, for which novel computational tools play a key role. For this purpose, we developed the Java-based conversion modules KGML2SBML and KGML2BioPAX to translate KGML (KEGG Markup Language) into a couple of common data exchange formats: SBML (Systems Biology Markup Language) and BioPAX (Biological Pathway Exchange). We hope that our work will be beneficial for other Java developers when they extend their bioinformatics system into SBML- or BioPAX-aware analysis tools. This is part of our ongoing effort to develop an ultimate KEGG-based pathway enrichment analysis system.

• Applied Microscopy
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• 제45권3호
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• pp.150-154
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• 2015

Negative staining electron microscopy facilitates the visualization of small bio-materials such as proteins; thus, many electron microscopists have used this conventional method to visualize the morphologies and structures of biological materials. To achieve sufficient contrast of the materials, a number of imaging parameters must be considered. Here, we examined the effects of one of the fundamental imaging parameters, electron beam exposure time, on electron densities generated using transmission electron microscopy. A single site of a negatively stained biological sample was illuminated with the electron beam for different times (1, 2, or 4 seconds) and sets of micrographs were collected. Computational image processing demonstrated that longer exposure times provide better electron densities at the molecular level. This report describes technical procedures for testing parameters that allow enhanced evaluations of the densities of electron microscopy images.

• 한국항공운항학회지
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• 제14권3호
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• pp.51-59
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• 2006

The air purity-sterilizer was developed and the CFD and experimental studies were carried out in order to investigate the performance of a air purity-sterilizer. Overhaul and exchange efficiency were increased by the modularization of the air purity-sterilizer. The good performance was validated by the hot-wire measurements and flow simulations in the room. Mean velocities at the exit of the air purity-sterilizer were 0.91, 1.62, 1.99, and 6.14 m/sec according to the fan mode. And the flow visualization of pured air was shown by using CFD flow simulation in the room of 24, 50 pyeong. The results show that the air purity-sterilizer has a high performance enough to produce air purity-sterilizer on a commercial scale.

• 응용통계연구
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• 제25권6호
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• pp.1009-1018
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• 2012

Persistence homology (a type of methodology in computational algebraic topology) can be used to capture the topological characteristics of functional data. To visualize the characteristics, a persistence diagram is adopted by plotting baseline and the pairs that consist of local minimum and local maximum. We use the bottleneck distance to measure the topological distance between two different functions; in addition, this distance can be applied to multidimensional scaling(MDS) that visualizes the imaginary position based on the distance between functions. In this study, we use handwriting data (which has functional forms) to get persistence diagram and check differences between the observations by using bottleneck distance and the MDS.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2006년도 추계학술대회 논문집
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• pp.145-148
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• 2006

In order to design a micro-thruster which controls the altitude of a space vehicle for a very long lifetime, the flow field should be analyzed considering the nozzle geometry and the difference between stagnation and environmental pressures and so on. This paper describes the axisymmetric non-reacted computational results which were carried out to understand the basic flow phenomena according to the high nozzle pressure ratio. The area ratio is about 56 and the diameter of a nozzle exit is about 0.46 inch. The Mach cell and waves are predicted well.